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1. 发明申请

US20110054274A1 DEVICE AND METHOD FOR WITHDRAWING BODY FLUID 有权
标题翻译：用于取出身体液体的装置和方法
公开(公告)号：US20110054274A1
公开(公告)日：2011-03-03
申请号：US12854665
申请日：2010-08-11
申请人： Hans List , Wolfgang Rödel , Christian Hörauf
发明人： Hans List , Wolfgang Rödel , Christian Hörauf
IPC分类号： A61B5/151 , A61B5/157
CPC分类号： A61B5/1411 , A61B5/150022 , A61B5/150198 , A61B5/150358 , A61B5/150419 , A61B5/150503 , A61B5/150748 , A61B5/15103 , A61B5/15113 , A61B5/15115 , A61B5/15117 , A61B5/15123 , A61B5/15128 , A61B5/1519 , A61B5/15194
摘要： The invention relates to a device for removing body fluid with a puncture element that can puncture the skin of a body part. The device includes a housing structure for body fluids obtained from the skin puncture and a puncture drive for a back and forth movement of the puncture element. The duration of withdrawal movement is longer than the duration of the forward movement. The puncture drive is designed to withdraw the puncture element in a first withdrawal phase of the withdrawal movement with a maximum withdrawal speed of more than 0.02 m/s. A second retraction phase follows the first retraction phase. Body fluid is collected during the second retraction phase, which has a duration of between 0.3 and 0.8 seconds and/or a retraction speed of between 0.6 and 2 mm/s.
摘要翻译：本发明涉及一种能够刺穿身体部位皮肤的穿刺元件去除体液的装置。该装置包括从皮肤穿刺获得的体液的外壳结构和用于穿刺元件的往复运动的穿刺驱动器。撤离运动的持续时间长于前进运动的持续时间。穿刺驱动器被设计成在抽出运动的第一撤回阶段以最大撤出速度大于0.02m / s的方式抽出穿刺元件。在第一回缩阶段之后的第二回缩阶段。在第二回缩阶段期间收集体液，其持续时间为0.3至0.8秒和/或0.6至2mm / s之间的收缩速度。

2. 发明授权

US09028426B2 Device and method for withdrawing body fluid 有权
标题翻译：用于抽出体液的装置和方法
公开(公告)号：US09028426B2
公开(公告)日：2015-05-12
申请号：US12854665
申请日：2010-08-11
申请人： Hans List , Wolfgang Rödel , Christian Hörauf
发明人： Hans List , Wolfgang Rödel , Christian Hörauf
IPC分类号： A61B5/15 , A61B5/151
CPC分类号： A61B5/1411 , A61B5/150022 , A61B5/150198 , A61B5/150358 , A61B5/150419 , A61B5/150503 , A61B5/150748 , A61B5/15103 , A61B5/15113 , A61B5/15115 , A61B5/15117 , A61B5/15123 , A61B5/15128 , A61B5/1519 , A61B5/15194
摘要： The invention relates to a device for removing body fluid with a puncture element that can puncture the skin of a body part. The device includes a housing structure for body fluids obtained from the skin puncture and a puncture drive for a back and forth movement of the puncture element. The duration of withdrawal movement is longer than the duration of the forward movement. The puncture drive is designed to withdraw the puncture element in a first withdrawal phase of the withdrawal movement with a maximum withdrawal speed of more than 0.02 m/s. A second retraction phase follows the first retraction phase. Body fluid is collected during the second retraction phase, which has a duration of between 0.3 and 0.8 seconds and/or a retraction speed of between 0.6 and 2 mm/s.
摘要翻译：本发明涉及一种能够刺穿身体部位皮肤的穿刺元件去除体液的装置。该装置包括从皮肤穿刺获得的体液的外壳结构和用于穿刺元件的往复运动的穿刺驱动器。撤离运动的持续时间长于前进运动的持续时间。穿刺驱动器被设计成在抽出运动的第一撤回阶段以最大撤出速度大于0.02m / s的方式抽出穿刺元件。在第一回缩阶段之后的第二回缩阶段。在第二回缩阶段期间收集体液，其持续时间为0.3至0.8秒和/或0.6至2mm / s之间的收缩速度。

3. 发明授权

US08231547B2 Puncturing system for withdrawing a body fluid 有权
标题翻译：用于抽出体液的穿刺系统
公开(公告)号：US08231547B2
公开(公告)日：2012-07-31
申请号：US11849280
申请日：2007-09-01
申请人： Frank Deck , Ortrud Quarder , Thomas Weiss , Christian Hörauf , Michael Keil , Ahmet Konya , Herbert Harttig , Felix Baader , Hans List , Karl-Peter Ebert
发明人： Frank Deck , Ortrud Quarder , Thomas Weiss , Christian Hörauf , Michael Keil , Ahmet Konya , Herbert Harttig , Felix Baader , Hans List , Karl-Peter Ebert
IPC分类号： A61B5/00
CPC分类号： A61B5/15148 , A61B5/150022 , A61B5/15019 , A61B5/150198 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150572 , A61B5/150832 , A61B5/150916 , A61B5/15113 , A61B5/15117 , A61B5/15128 , A61B5/1519 , A61B5/15194 , A61B5/15196
摘要： The present invention provides a puncturing system for withdrawing body fluid. The puncturing system comprises a disposable puncturing unit, which includes a needle element for piercing into skin and a puncturing depth reference element with a skin contact area. The system includes a puncturing instrument which has a puncturing drive, wherein the puncturing drive is coupled by a coupling mechanism to the puncturing unit for driving the needle element to a puncturing depth, the puncturing depth being determined by the distance in the piercing direction between the skin contact area and the position of the tip of the needle at a reversal point of the puncturing movement. The puncturing depth reference element is connected to the needle element such that the puncturing depth reference element moves with the needle element during at least part of the puncturing movement. The puncturing depth reference element has a defined longitudinal position in the piercing direction relative to the needle element at least at the reversal point of the puncturing movement.
摘要翻译：本发明提供一种用于抽出体液的穿刺系统。穿刺系统包括一次性穿刺单元，其包括用于刺入皮肤的针元件和具有皮肤接触区域的穿刺深度参考元件。该系统包括具有穿刺驱动器的穿刺器具，其中穿刺驱动器通过联接机构联接到穿刺单元，用于将针元件驱动到穿刺深度，穿刺深度由穿刺方向上的距离确定皮肤接触区域和针的尖端在穿刺运动的反转点处的位置。穿刺深度参考元件连接到针元件，使得穿刺深度参考元件在穿刺运动的至少一部分期间与针元件一起移动。穿刺深度参考元件至少在穿刺运动的反转点处具有相对于针元件在穿刺方向上的限定的纵向位置。

4. 发明授权

US09883828B2 Test element and test system for examining a body fluid 有权
公开(公告)号：US09883828B2
公开(公告)日：2018-02-06
申请号：US12101971
申请日：2008-04-12
申请人： Hans-Peter Haar , Hans List
发明人： Hans-Peter Haar , Hans List
IPC分类号： A61B5/00 , A61B5/157 , A61B5/145 , A61B5/1459 , G01N21/77 , A61B5/15 , A61B5/151
CPC分类号： A61B5/157 , A61B5/14532 , A61B5/1459 , A61B5/150022 , A61B5/150419 , A61B5/150435 , A61B5/150511 , A61B5/150519 , A61B5/15107 , A61B5/15115 , A61B5/15151 , A61B5/15163 , A61B5/15174 , A61B5/6848 , G01N21/7703 , G01N2021/7773
摘要： The invention relates to a test element as a single-use article for examining a body fluid, comprising a lancing member that can be inserted into a body part, a collecting area configured thereon for body fluid obtained by the lancing and at least one light guide for an optical measurement in the collecting area. The collecting area is formed by a collection recess of the lancing member which extends in the lancing direction and the light guide is integrated into the lancing member such that it is secure against displacement and the distal end thereof is arranged in a proximal measurement zone of the collection recess.

5. 发明授权

US09439591B2 Analysis system and method for determining an analyte in a body fluid 有权
标题翻译：用于测定体液中分析物的分析系统和方法
公开(公告)号：US09439591B2
公开(公告)日：2016-09-13
申请号：US12962000
申请日：2010-12-07
申请人： Stephan-Michael Frey , Hans List , Andrea Rittinghaus , Volker Zimmer , Guenter Ihle , Wolfgang Roedel
发明人： Stephan-Michael Frey , Hans List , Andrea Rittinghaus , Volker Zimmer , Guenter Ihle , Wolfgang Roedel
IPC分类号： A61B5/157 , A61B5/15 , A61B5/145 , A61B5/1455 , A61B5/151
CPC分类号： A61B5/157 , A61B5/1411 , A61B5/14532 , A61B5/1455 , A61B5/150022 , A61B5/150358 , A61B5/150419 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/15113 , A61B5/15123 , A61B5/1513 , A61B5/15146 , A61B5/15151 , A61B5/15163
摘要： A system for determining an analyte in a body fluid includes a magazine comprising two partial magazines, one including chambers containing analysis elements having a sample contact zone and a reagent system containing a reagent, whose reaction with the body fluid results in a change of a variable, and another including chambers containing puncturing elements having a tip having a capillary channel, which forms a fluid connection between the tip and a sample transfer zone of the puncturing element. The system may also include an analysis instrument having a puncturing drive for driving a puncturing element on a movement path, a mounting for receiving the magazine such that one chamber of the magazine at a time is located in a functional position, in which a puncturing element in the chamber can be moved by the puncturing drive, and a measuring and evaluation apparatus for measuring the change of the variable.
摘要翻译：用于确定体液中的分析物的系统包括：包含两个部分杂志的盒，一个包括具有样品接触区的分析元件的腔室和含有试剂的试剂系统，其与体液的反应导致变量，另一个包括具有具有毛细通道的尖端的穿刺元件的腔室，其形成尖端和穿刺元件的样品转移区域之间的流体连接。该系统还可以包括具有用于在移动路径上驱动穿刺元件的穿刺驱动器的分析仪器，用于接收盒子的安装件，使得一次一次的仓库位于功能位置，其中穿刺元件可以通过穿刺驱动器移动腔室，以及用于测量变量的变化的测量和评估装置。

6. 发明授权

US09289162B2 Control device for a medical test system 有权
标题翻译：用于医疗测试系统的控制装置
公开(公告)号：US09289162B2
公开(公告)日：2016-03-22
申请号：US13365404
申请日：2012-02-03
申请人： Hans-Juergen Kuhr , Herbert Harttig , Hans-Peter Haar , Hans List
发明人： Hans-Juergen Kuhr , Herbert Harttig , Hans-Peter Haar , Hans List
IPC分类号： A61B5/00 , A61B5/15 , A61B5/145 , A61B5/1459 , A61B5/151 , A61B5/157
CPC分类号： A61B5/1411 , A61B5/14532 , A61B5/1459 , A61B5/150022 , A61B5/150175 , A61B5/150419 , A61B5/150435 , A61B5/150503 , A61B5/150946 , A61B5/15117 , A61B5/15123 , A61B5/15128 , A61B5/1513 , A61B5/15132 , A61B5/15186 , A61B5/1519 , A61B5/15194 , A61B5/157
摘要： The invention concerns a control device for a medical test system which has a lancing element that can be inserted into body tissue to collect body fluid and a lancing drive for the lancing element. A sensor element for body fluid is arranged on the lancing element and a control unit is coupled to the sensor element for detecting a fault when collecting body fluid. In order to improve the success rate, the control unit actuates the lancing drive for an automatic puncture repetition in less than 1 second when a fault, e.g., inadequate wetting of a detection field, occurs.
摘要翻译：本发明涉及用于医疗测试系统的控制装置，其具有可以插入身体组织以收集体液的穿刺元件和用于穿刺元件的穿刺驱动器。用于体液的传感器元件布置在穿刺元件上，并且控制单元联接到传感器元件，用于在收集体液时检测故障。为了提高成功率，当出现故障（例如，检测场的不充分）时，控制单元在小于1秒钟内启动穿刺驱动以进行自动穿刺重复。

7. 发明授权

US08932313B2 Blood collection system for collecting blood from a body part for diagnostic purposes 有权
标题翻译：用于从身体部位收集血液用于诊断目的的采血系统
公开(公告)号：US08932313B2
公开(公告)日：2015-01-13
申请号：US11743410
申请日：2007-05-02
申请人： Thomas Weiss , Hans List
发明人： Thomas Weiss , Hans List
IPC分类号： A61B17/32 , A61B5/15
CPC分类号： A61B5/1411 , A61B5/150022 , A61B5/15019 , A61B5/150236 , A61B5/150412 , A61B5/150503 , A61B5/15117 , A61B5/1519 , A61B5/15194
摘要： A blood collection system for collecting blood from a body part for diagnostic purposes, comprising a housing with a lancet guide, by which a lancet is guided on a predetermined puncture path, and a lancet drive for driving a puncturing movement of the lancet on the predetermined puncture path. The puncturing movement comprises a forward movement phase in the direction of puncturing and, after reaching a reversal point, a subsequent retraction movement phase in the direction opposite the puncture direction. The lancet drive has a driving spring, which is arranged behind the lancet and is connected to the lancet during the forward movement phase of the puncturing movement so that the lancet is driven in the puncturing direction. The system comprises an oscillation control device for controlling oscillation of the lancet and the driving spring in such a manner that repeated puncturing of the body part by the lancet is prevented.
摘要翻译：一种用于从身体部分收集用于诊断目的的血液的采血系统，包括：具有刺血针引导件的壳体，穿刺针在预定穿刺路径上被引导;以及刺血针驱动器，用于在所述预定的穿刺引导件上驱动刺血针的穿刺运动穿刺路径穿刺动作包括在穿刺方向上的向前移动相位，并且在到达反转点之后，沿与穿刺方向相反的方向的后续的缩回移动相位。刺血针驱动器具有驱动弹簧，该驱动弹簧布置在刺血针后面，并且在穿刺运动的向前运动阶段期间连接到刺血针，使得刺血针沿穿刺方向被驱动。该系统包括用于控制刺血针和驱动弹簧的振动的振荡控制装置，以防止柳叶刀重复穿刺身体部位。

8. 发明授权

US08888715B2 Analysis system and method for determining an analyte in a body fluid with a magazine comprising integrated sample acquisition and analyzing elements 有权
标题翻译：用于使用包含集成样品采集和分析元件的盒子来确定体液中的分析物的分析系统和方法
公开(公告)号：US08888715B2
公开(公告)日：2014-11-18
申请号：US12712236
申请日：2010-02-25
申请人： Hans List , Stephan-Michael Frey , Kai Fluegge
发明人： Hans List , Stephan-Michael Frey , Kai Fluegge
IPC分类号： A61B5/00 , B65D81/00 , A61B5/15 , A61B5/151
CPC分类号： A61B5/1405 , A61B5/150022 , A61B5/150358 , A61B5/150419 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/15115 , A61B5/1513 , A61B5/15146 , A61B5/15151 , A61B5/15174 , A61B5/15176 , A61B5/157
摘要： Analysis system for determining an analyte in a body fluid is presented. The system comprises a reusable analysis instrument and a magazine having a plurality of integrated sample acquisition and analyzing elements. Each element comprises a puncturing element and an analyzing element. A coupling unit couples the integrated sample acquisition and analyzing element to a drive. The magazine comprises a housing having a plurality of elongate neighboring chambers separated by two side walls running in a longitudinal. The chambers contain the integrated sample acquisition and analyzing element. The chambers have an exit opening allowing for the at least partial exiting of the puncturing element. The chambers of the magazine are accessible to a coupling element that can be formfitting coupled to the coupling structure of the puncturing element, when the puncturing element is in the chamber of the magazine and the magazine is located in a holder.
摘要翻译：提出了用于确定体液中分析物的分析系统。该系统包括可重复使用的分析仪器和具有多个集成样品采集和分析元件的杂志。每个元件包括穿刺元件和分析元件。耦合单元将集成的采样和分析元件耦合到驱动器。该杂志包括具有由纵向延伸的两个侧壁隔开的多个细长相邻室的壳体。这些室包含集成的采样和分析元件。腔室具有允许穿刺元件的至少部分离开的出口。当穿刺元件位于钉仓的腔室中并且刀库位于保持器中时，可以将联接元件接近联接元件，该联接元件可被联接到穿刺元件的联接结构上。

9. 发明授权

US08414609B2 Lancet device for generating a puncture wound, and lancet drive assembly 有权
标题翻译：用于产生穿刺伤口的刺血针装置和刺血针驱动组件
公开(公告)号：US08414609B2
公开(公告)日：2013-04-09
申请号：US12717359
申请日：2010-03-04
申请人： Hans List
发明人： Hans List
IPC分类号： A61B17/32 , A61B5/151
CPC分类号： A61B5/150198 , A61B5/150022 , A61B5/150412 , A61B5/150503 , A61B5/150755 , A61B5/15113 , A61B5/15117 , A61B5/15128 , A61B5/1513 , A61B5/15146 , A61B5/1519 , A61B5/15194
摘要： A lancet device for generating a puncture wound in a skin surface, comprising a housing, in which a lancet can be moved on a puncturing path, a lancet drive with a drive rotor that can be driven by a drive spring, a lancet coupling mechanism that transforms a rotational motion of the drive rotor into a puncturing and returning motion of the lancet during a working cycle of the lancet drive, a reference element that is mobile relative to the lancet and relative to the housing and is fixed in a defined position relative to the lancet drive during the puncturing and rests against the surface of the skin with a contact surface thereof such that a puncture wound with a reproducible puncturing depth is generated by the puncturing motion, and a reference element coupling mechanism that is coupled to the lancet drive in order to move the reference element. The invention further relates to a suitable lancet drive assembly for a lancet device of this type.
摘要翻译：一种用于在皮肤表面产生穿刺伤口的刺血针装置，其特征在于，具有可以在穿刺路径上移动刺血针的壳体，能够由驱动弹簧驱动的驱动转子的柳叶刀驱动器，将所述驱动转子的旋转运动变换成在所述柳叶刀驱动器的工作循环期间所述刺血针的穿刺和返回运动，所述参考元件相对于所述刺血针并且相对于所述壳体是可移动的并且相对于所述壳体被固定在限定位置在穿刺期间的刺血针驱动器和其接触表面靠在皮肤表面上，使得通过穿刺运动产生以可再现的穿刺深度缠绕的穿刺，以及参考元件联接机构，其连接到刺血针驱动器命令移动参考元素。本发明还涉及一种用于这种类型的刺血针装置的合适的柳叶刀驱动组件。

10. 发明授权

US08394117B2 Handheld apparatus for creating a puncture wound 有权
标题翻译：用于创建穿刺伤口的手持设备
公开(公告)号：US08394117B2
公开(公告)日：2013-03-12
申请号：US12040905
申请日：2008-03-02
申请人： Heinz-Michael Hein , Irio Calasso , Hans List
发明人： Heinz-Michael Hein , Irio Calasso , Hans List
IPC分类号： A61B17/14 , A61B17/32 , A61B17/34 , B26F1/24
CPC分类号： A61B5/157 , A61B5/150022 , A61B5/150068 , A61B5/150152 , A61B5/150175 , A61B5/150419 , A61B5/150427 , A61B5/150511 , A61B5/15123 , A61B5/1519 , A61B5/15194 , Y10T83/0481
摘要： The invention relates to a method for creating a puncture wound for obtaining a sample of a body fluid from a body part in which a skin opening is created at a puncture site in the epidermis in a skin-opening step. Then, in a sample collection step a sample collection puncture is executed by using a puncture element with which the skin opening is deepened with the puncture element, thereby creating a puncture wound for obtaining the sample. The invention also relates to a handheld apparatus for implementing this method.
摘要翻译：本发明涉及一种创造穿刺伤口的方法，该穿刺伤口从皮肤开放步骤中在表皮的穿刺位置处产生皮肤开口的身体部位获得体液样品。然后，在取样步骤中，通过使用与穿刺元件加深皮肤开口的穿刺元件进行样本采集穿刺，由此形成用于获取样本的穿刺伤口。本发明还涉及一种用于实现该方法的手持设备。

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