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1. 发明授权

US06501990B1 Extendable and retractable lead having a snap-fit terminal connector 有权
标题翻译：具有卡扣式端子连接器的可伸缩的引线
公开(公告)号：US06501990B1
公开(公告)日：2002-12-31
申请号：US09472098
申请日：1999-12-23
申请人： Gregory L. Sundberg , David M. Flynn , Michael Brenzel , Jason Skubitz , Larry L. Hum , Carol Werlein , Christopher Paul Knapp , Gregory R. Ley , Jason Alan Shiroff , Brian David Soltis
发明人： Gregory L. Sundberg , David M. Flynn , Michael Brenzel , Jason Skubitz , Larry L. Hum , Carol Werlein , Christopher Paul Knapp , Gregory R. Ley , Jason Alan Shiroff , Brian David Soltis
IPC分类号： A61N105
CPC分类号： A61N1/0563 , A61N1/056 , A61N1/0573 , A61N1/3752 , Y10T29/49204 , Y10T29/49208 , Y10T29/49217
摘要： A lead having an extendable and retractable fixation mechanism has a rotating terminal pin at the terminal end which rotates the fixation mechanism at the distal end. As the terminal pin is rotated, the fixation mechanism is extended or retracted from the distal end of the lead. A threaded collar allows for the fixation mechanism to smoothly extend and retract from the lead, and allows for a 1:1 turn ratio between the terminal pin and the fixation mechanism. A fluoroscopic ring disposed at the distal end of the lead provides information during the implantation process. The lead includes a terminal assembly having an outer terminal ring, a terminal pin, and an insulative sleeve disposed between the outer terminal ring and the terminal pin. The insulative sleeve is coupled with the outer terminal ring with a snap-fit connection.
摘要翻译：具有可伸缩的固定机构的引线具有在终端处的旋转端子销，其在远端旋转固定机构。当端子销旋转时，固定机构从引线的远端延伸或缩回。螺纹轴环允许固定机构从引线平滑地延伸和缩回，并且允许端子销和固定机构之间的1:1的匝数比。设置在引线远端的荧光镜环在植入过程中提供信息。引线包括具有外端子环，端子引脚和布置在外端子环和端子引脚之间的绝缘套管的端子组件。绝缘套管与外部端子环与卡扣配合连接。

2. 发明授权

US08209035B2 Extendable and retractable lead having a snap-fit terminal connector 有权
标题翻译：具有卡扣式端子连接器的可伸缩的引线
公开(公告)号：US08209035B2
公开(公告)日：2012-06-26
申请号：US12144316
申请日：2008-06-23
申请人： David M. Flynn , Michael Brenzel , Jason Skubitz , Larry L. Hum , Carol Werlein , Christopher Paul Knapp , Gregory R. Ley , Jason Alan Shiroff , Brian David Soltis
发明人： David M. Flynn , Michael Brenzel , Jason Skubitz , Larry L. Hum , Carol Werlein , Christopher Paul Knapp , Gregory R. Ley , Jason Alan Shiroff , Brian David Soltis
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0573 , A61N1/3752 , Y10S439/909
摘要： A lead having an extendable and retractable fixation mechanism has a rotating terminal pin at the terminal end which rotates the fixation mechanism at the distal end. As the terminal pin is rotated, the fixation mechanism is extended or retracted from the distal end of the lead. A threaded collar allows for the fixation mechanism to smoothly extend and retract from the lead, and allows for a 1:1 turn ratio between the terminal pin and the fixation mechanism. A fluoroscopic ring disposed at the distal end of the lead provides information during the implantation process.
摘要翻译：具有可伸缩的固定机构的引线具有在终端处的旋转端子销，其在远端旋转固定机构。当端子销旋转时，固定机构从引线的远端延伸或缩回。螺纹轴环允许固定机构从引线平滑地延伸和缩回，并且允许端子销和固定机构之间的1:1的匝数比。设置在引线远端的荧光镜环在植入过程中提供信息。

3. 发明申请

US20080262587A1 EXTENDABLE AND RETRACTABLE LEAD HAVING A SNAP-FIT TERMINAL CONNECTOR 有权
标题翻译：具有连接端子连接器的可扩展和可退回的引线
公开(公告)号：US20080262587A1
公开(公告)日：2008-10-23
申请号：US12144316
申请日：2008-06-23
申请人： David M. Flynn , Michael Brenzel , Jason Skubitz , Larry L. Hum , Carol Werlein , Christopher Paul Knapp , Gregory R. Ley , Jason Alan Shiroff , Brian David Soltis
发明人： David M. Flynn , Michael Brenzel , Jason Skubitz , Larry L. Hum , Carol Werlein , Christopher Paul Knapp , Gregory R. Ley , Jason Alan Shiroff , Brian David Soltis
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0573 , A61N1/3752 , Y10S439/909
摘要： A lead having an extendable and retractable fixation mechanism has a rotating terminal pin at the terminal end which rotates the fixation mechanism at the distal end. As the terminal pin is rotated, the fixation mechanism is extended or retracted from the distal end of the lead. A threaded collar allows for the fixation mechanism to smoothly extend and retract from the lead, and allows for a 1:1 turn ratio between the terminal pin and the fixation mechanism. A fluoroscopic ring disposed at the distal end of the lead provides information during the implantation process.
摘要翻译：具有可伸缩的固定机构的引线具有在终端处的旋转端子销，其在远端旋转固定机构。当端子销旋转时，固定机构从引线的远端延伸或缩回。螺纹轴环允许固定机构从引线平滑地延伸和缩回，并且允许端子销和固定机构之间的1:1的匝数比。设置在引线远端的荧光镜环在植入过程中提供信息。

4. 发明授权

US07392095B2 Extendable and retractable lead having a snap-fit terminal connector 有权
标题翻译：具有卡扣式端子连接器的可伸缩的引线
公开(公告)号：US07392095B2
公开(公告)日：2008-06-24
申请号：US11173664
申请日：2005-07-01
申请人： David M. Flynn , Michael Brenzel , Jason Skubitz , Larry L. Hum , Carol Werlein , Christopher Paul Knapp , Gregory R. Ley , Jason Alan Shiroff , Brian David Soltis
发明人： David M. Flynn , Michael Brenzel , Jason Skubitz , Larry L. Hum , Carol Werlein , Christopher Paul Knapp , Gregory R. Ley , Jason Alan Shiroff , Brian David Soltis
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0573 , A61N1/3752 , Y10S439/909
摘要： A lead having an extendable and retractable fixation mechanism has a rotating terminal pin at the terminal end which rotates the fixation mechanism at the distal end. As the terminal pin is rotated, the fixation mechanism is extended or retracted from the distal end of the lead. A threaded collar allows for the fixation mechanism to smoothly extend and retract from the lead, and allows for a 1:1 turn ratio between the terminal pin and the fixation mechanism. A fluoroscopic ring disposed at the distal end of the lead provides information during the implantation process.
摘要翻译：具有可伸缩的固定机构的引线具有在终端处的旋转端子销，其在远端旋转固定机构。当端子销旋转时，固定机构从引线的远端延伸或缩回。螺纹轴环允许固定机构从引线平滑地延伸和缩回，并且允许端子销和固定机构之间的1:1的匝数比。设置在引线远端的荧光镜环在植入过程中提供信息。

5. 发明授权

US06915169B2 Extendable and retractable lead having a snap-fit terminal connector 有权
公开(公告)号：US06915169B2
公开(公告)日：2005-07-05
申请号：US10264494
申请日：2002-10-04
申请人： David M. Flynn , Michael Brenzel , Jason Skubitz , Larry L. Hum , Carol Werlein , Christopher Paul Knapp , Gregory R. Ley , Jason Alan Shiroff , Brian David Soltis
发明人： David M. Flynn , Michael Brenzel , Jason Skubitz , Larry L. Hum , Carol Werlein , Christopher Paul Knapp , Gregory R. Ley , Jason Alan Shiroff , Brian David Soltis
IPC分类号： A61N1/05 , A61N1/375
CPC分类号： A61N1/056 , A61N1/0573 , A61N1/3752 , Y10S439/909
摘要： A lead having an extendable and retractable fixation mechanism has a rotating terminal pin at the terminal end which rotates the fixation mechanism at the distal end. As the terminal pin is rotated, the fixation mechanism is extended or retracted from the distal end of the lead. A threaded collar allows for the fixation mechanism to smoothly extend and retract from the lead, and allows for a 1:1 turn ratio between the terminal pin and the fixation mechanism. A fluoroscopic ring disposed at the distal end of the lead provides information during the implantation process.

6. 发明授权

US06463334B1 Extendable and retractable lead 有权
标题翻译：具有卡扣式端子连接器的可伸缩的引线
公开(公告)号：US06463334B1
公开(公告)日：2002-10-08
申请号：US09359580
申请日：1999-07-22
申请人： David M. Flynn , Michael Brenzel , Jason Skubitz , Larry L. Hum , Carol Werlein , Christopher Paul Knapp , Gregory R. Ley , Jason Alan Shiroff , Brian David Soltis
发明人： David M. Flynn , Michael Brenzel , Jason Skubitz , Larry L. Hum , Carol Werlein , Christopher Paul Knapp , Gregory R. Ley , Jason Alan Shiroff , Brian David Soltis
IPC分类号： A61N105
CPC分类号： A61N1/056 , A61N1/0573 , A61N1/3752 , Y10S439/909
摘要： A lead having an extendable and retractable fixation mechanism has a rotating terminal pin at the terminal end which rotates the fixation mechanism at the distal end. As the terminal pin is rotated, the fixation mechanism is extended or retracted from the distal end of the lead. A threaded collar allows for the fixation mechanism to smoothly extend and retract from the lead, and allows for a 1:1 turn ratio between the terminal pin and the fixation mechanism. A fluoroscopic ring disposed at the distal end of the lead provides information during the implantation process.
摘要翻译：具有可伸缩的固定机构的引线具有在终端处的旋转端子销，其在远端旋转固定机构。当端子销旋转时，固定机构从引线的远端延伸或缩回。螺纹轴环允许固定机构从引线平滑地延伸和缩回，并且允许端子销和固定机构之间的1:1的匝数比。设置在引线远端的荧光镜环在植入过程中提供信息。

7. 发明授权

US07089046B2 Removable cap for tissue-insertable connections 有权
标题翻译：用于组织可插入连接的可拆卸盖
公开(公告)号：US07089046B2
公开(公告)日：2006-08-08
申请号：US10187514
申请日：2002-07-02
申请人： Ronald W. Heil, Jr. , Gregory R. Ley , Dwight Skinner , Larry L. Hum
发明人： Ronald W. Heil, Jr. , Gregory R. Ley , Dwight Skinner , Larry L. Hum
IPC分类号： A61B5/04
CPC分类号： A61N1/0573
摘要： A helical element for insertion into tissue comprises a helical element having an insertion end, a protruding end and an open central area within the wire, rods, filaments, cables or the like that form the helix. The helical element has at least its insertion end covered by a cap of a water-soluble or water-dispersible composition. The cap is provided with a surface shape in a cross-section in which surface variations are present in the cross-section which create a surface orientation where a line from the center of the cross-section can intersect the surface, and a line perpendicular to said radius at a point of intersection with said surface forms four quadrants, three of said quadrants containing water-soluble or water-dispersible cap material. There is either a hollow area within the composition within the open central area or the material is more porous than the remaining material. The helical element preferably comprises an electrical lead, such as a positive endocardial lead, with an electrode at the protruding or distal end of the lead.The helical element may comprise any biocompatable material with sufficient structural integrity to provide a secure attachment to tissue in a patient. Where the helical element is also to provide an active (electrically active) function, the composition of the helical element should also be electrically conductive.
摘要翻译：用于插入组织的螺旋元件包括螺旋元件，其具有插入端，突出端和形成螺旋的线内的开口中心区域，杆，细丝，电缆等。螺旋元件的至少其插入端被水溶性或水分散性组合物的盖子覆盖。该盖在横截面中具有表面形状，其中在横截面中存在表面变化，其形成表面取向，其中横截面中心的线可以与表面相交，并且垂直于在与所述表面的交点处的所述半径形成四个象限，所述象限中的三个包含水溶性或水分散性盖材料。组合物中的中空区域在开放的中心区域内，或者材料比剩余的材料多孔。螺旋元件优选地包括电引线，例如正心内膜引线，在引线的突出或远端具有电极。

8. 发明授权

US06473633B1 Removable cap for tissue-insertable connections 失效
标题翻译：用于组织可插入连接的可拆卸盖
公开(公告)号：US06473633B1
公开(公告)日：2002-10-29
申请号：US09363477
申请日：1999-07-29
申请人： Ronald W. Heil, Jr. , Gregory R. Ley , Dwight Skinner , Larry L. Hum
发明人： Ronald W. Heil, Jr. , Gregory R. Ley , Dwight Skinner , Larry L. Hum
IPC分类号： A61B5042
CPC分类号： A61N1/0573
摘要： A helical element for insertion into tissue comprises a helical element having an insertion end, a protruding end and an open central area within the wire, rods, filaments, cables or the like that form the helix. The helical element has at least its insertion end covered by a cap of a water-soluble or water-dispersible composition. The cap is provided with a surface shape in a cross-section in which surface variations are present in the cross-section which create a surface orientation where a line from the center of the cross-section can intersect the surface, and a line perpendicular to said radius at a point of intersection with said surface forms four quadrants, three of said quadrants containing water-soluble or water-dispersible cap material. There is either a hollow area within the composition within the open central area or the material is more porous than the remaining material. The helical element preferably comprises an electrical lead, such as a positive endocardial lead, with an electrode at the protruding or distal end of the lead. The helical element may comprise any biocompatable material with sufficient structural integrity to provide a secure attachment to tissue in a patient. Where the helical element is also to provide an active (electrically active) function, the composition of the helical element should also be electrically conductive.
摘要翻译：用于插入组织的螺旋元件包括螺旋元件，其具有插入端，突出端和形成螺旋的线内的开口中心区域，杆，细丝，电缆等。螺旋元件的至少其插入端被水溶性或水分散性组合物的盖子覆盖。盖在横截面中设置有表面形状，其中在横截面中存在表面变化，其产生表面取向，其中横截面中心的线可以与表面相交，并且垂直于在与所述表面的交点处的所述半径形成四个象限，所述象限中的三个包含水溶性或水分散性盖材料。组合物中的中空区域在开放的中心区域内，或者材料比剩余的材料多孔。螺旋元件优选地包括电引线，例如正性心内膜引线，在引线的突出或远端具有电极。螺旋元件可以包括具有足够结构完整性的任何可生物相容的材料，以提供与患者。当螺旋元件也提供活性（电活性）功能时，螺旋元件的组成也应当是导电的。

9. 发明授权

US06360129B1 Mannitol/hydrogel cap for tissue-insertable connections 有权
标题翻译：用于组织可插入连接的甘露醇/水凝胶帽
公开(公告)号：US06360129B1
公开(公告)日：2002-03-19
申请号：US09459782
申请日：1999-12-13
申请人： Gregory R. Ley , Larry L. Hum
发明人： Gregory R. Ley , Larry L. Hum
IPC分类号： A61N100
CPC分类号： A61N1/0573 , A61N2001/058
摘要： A helical element for insertion into tissue comprises a helical element having an insertion end, a protruding end and an open central area within the wire, rods, filaments, cables or the like that form the helix. The helical element has at least its insertion end covered by a cap of a water-soluble or water-dispersible composition. The composition of the cap comprises a water-soluble or water dispersible component having a hydrogel mixed therein. In one embodiment, there is either a hollow area within the composition within the open central area or the material is more porous than the remaining material. The helical element preferably comprises an electrical lead, such as a positive endocardial lead, with an electrode at the protruding or distal end of the lead. The helical element may comprise any biocompatable material with sufficient structural integrity to provide a secure attachment to tissue in a patient. Where the helical element is also to provide an active (electrically active) function, the composition of the helical element should also be electrically conductive.
摘要翻译：用于插入组织的螺旋元件包括螺旋元件，其具有插入端，突出端和形成螺旋的线内的开口中心区域，杆，细丝，电缆等。螺旋元件的至少其插入端被水溶性或水分散性组合物的盖子覆盖。盖的组成包括其中混合有水凝胶的水溶性或水分散性组分。在一个实施方案中，组合物中的中空区域在开放中心区域内，或者材料比剩余材料更多孔。螺旋元件优选地包括电引线，例如正性心内膜引线，在引线的突出或远端具有电极。螺旋元件可以包括具有足够结构完整性的任何可生物相容的材料，以提供与患者。当螺旋元件也提供活性（电活性）功能时，螺旋元件的组成也应当是导电的。

10. 发明授权

US08372468B2 Surface modification to improve lubricity, abrasion resistance and temperature resilience of leads 有权
标题翻译：表面改性以提高导线的润滑性，耐磨性和温度弹性
公开(公告)号：US08372468B2
公开(公告)日：2013-02-12
申请号：US12547839
申请日：2009-08-26
申请人： Shrojalkumar Desai , Leslie J. Carion , Larry L. Hum
发明人： Shrojalkumar Desai , Leslie J. Carion , Larry L. Hum
IPC分类号： B05D5/08 , B05D3/00
CPC分类号： B05D5/08 , A61L31/10 , A61L31/14 , A61L2400/18 , C08J3/245 , C08J7/06 , C08L23/0853 , C08L83/04 , C08L2666/04
摘要： A medical electrical lead body having an outer surface and including at least one lumen having an inner surface treated with a silane surface modifying agent to form a three-dimensional, densely cross-linked lubricious coating over at least a portion of the inner surface of the lumen. The outer surface of the lead body also may be similarly treated. The lubricious silane coating may reduce the coefficient of friction of the coated surface of the lead body by as much as 80% when compared to an uncoated surface. A reduction in the coefficient of friction may enhance the stringing efficiency of a conductor through the lead body lumen and may enhance its abrasion resistance.
摘要翻译：一种具有外表面并且包括具有用硅烷表面改性剂处理的内表面的至少一个内腔的医疗电引线体，以在所述内表面的至少一部分上形成三维密集交联的光滑涂层流明。引线体的外表面也可以被类似地处理。与未涂覆的表面相比，润滑硅烷涂层可以将引线体的涂覆表面的摩擦系数降低多达80％。摩擦系数的降低可以提高导体通过引线体腔的穿线效率并且可以提高其耐磨性。

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