专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20120077189A1 SCAFFOLD-BASED POLYMERASE ENZYME SUBSTRATES 有权
标题翻译：基于SCAFFOLD的聚合酶酶基质
公开(公告)号：US20120077189A1
公开(公告)日：2012-03-29
申请号：US13218382
申请日：2011-08-25
申请人： Gene Shen , Lubomir Sebo , Stephen Yue , Wei-Chuan Sun , Louis Brogley , Andrei Fedorov
发明人： Gene Shen , Lubomir Sebo , Stephen Yue , Wei-Chuan Sun , Louis Brogley , Andrei Fedorov
IPC分类号： C12Q1/68 , C07H19/207
CPC分类号： C12Q1/6869 , C07D209/14 , C07D401/14 , C07D405/14 , C07H19/10 , C07K5/0815 , C07K5/1019 , C09B23/0025 , C09B23/0033 , C09B23/0066 , C09B23/06 , C09B23/083 , C09B23/105 , C09B23/164 , C12Q1/6844 , C12Q1/6876 , G01N33/52 , G01N33/582 , G01N2333/9126
摘要： The invention provides a novel class of scaffold-based labeled polymerase enzyme substrates. The polymerase enzyme substrates have a multivalent core or scaffold to which is attached fluorescent dye moieties and nucleoside phosphate moities. The polymerase enzyme substrates have multiple fluorescent dye moities and/or multiple nucleoside phosphate moieties. Preferred multivalent cores comprise trifunctional six membered aromatic moities. The invention also provides for sequencing methods and kits with scaffold-based labeled polymerase enzyme substrates.
摘要翻译：本发明提供了一类新型的基于支架的标记聚合酶底物。聚合酶底物具有连接有荧光染料部分和核苷磷酸酯多糖的多价核心或支架。聚合酶底物具有多个荧光染料体系和/或多个核苷磷酸酯部分。优选的多价核心包括三官能六元芳族部分。本发明还提供了使用基于支架的标记聚合酶底物的测序方法和试剂盒。

2. 发明授权

US08906612B2 Scaffold-based polymerase enzyme substrates 有权
标题翻译：基于脚手架的聚合酶底物
公开(公告)号：US08906612B2
公开(公告)日：2014-12-09
申请号：US13218382
申请日：2011-08-25
申请人： Gene Shen , Lubomir Sebo , Stephen Yue , Wei-Chuan Sun , Louis Brogley , Andrei Fedorov
发明人： Gene Shen , Lubomir Sebo , Stephen Yue , Wei-Chuan Sun , Louis Brogley , Andrei Fedorov
IPC分类号： C12Q1/68 , C07H21/00 , C07H21/02 , C07H21/04 , C09B23/06 , C07D209/14 , C09B23/01 , C09B23/08 , G01N33/58 , C07D401/14 , C07D405/14
CPC分类号： C12Q1/6869 , C07D209/14 , C07D401/14 , C07D405/14 , C07H19/10 , C07K5/0815 , C07K5/1019 , C09B23/0025 , C09B23/0033 , C09B23/0066 , C09B23/06 , C09B23/083 , C09B23/105 , C09B23/164 , C12Q1/6844 , C12Q1/6876 , G01N33/52 , G01N33/582 , G01N2333/9126
摘要： The invention provides a novel class of scaffold-based labeled polymerase enzyme substrates. The polymerase enzyme substrates have a multivalent core or scaffold to which is attached fluorescent dye moieties and nucleoside phosphate moities. The polymerase enzyme substrates have multiple fluorescent dye moities and/or multiple nucleoside phosphate moieties. Preferred multivalent cores comprise trifunctional six membered aromatic moities. The invention also provides for sequencing methods and kits with scaffold-based labeled polymerase enzyme substrates.
摘要翻译：本发明提供了一类新型的基于支架的标记聚合酶底物。聚合酶底物具有连接有荧光染料部分和核苷磷酸酯多糖的多价核心或支架。聚合酶底物具有多个荧光染料体系和/或多个核苷磷酸酯部分。优选的多价核心包括三官能六元芳族部分。本发明还提供了使用基于支架的标记聚合酶底物的测序方法和试剂盒。

3. 发明授权

US08388982B2 Photo-induced damage mitigating agents and preparation and methods of use thereof 有权
标题翻译：光诱导的损伤缓解剂及其制备方法及其使用方法
公开(公告)号：US08388982B2
公开(公告)日：2013-03-05
申请号：US12622375
申请日：2009-11-19
申请人： Xiangxu Kong , Gene Shen , Andrei Fedorov , John Lyle , Grace Lee , Lubomir Sebo , Duc Do , Robert Weber , Stephen Dudek
发明人： Xiangxu Kong , Gene Shen , Andrei Fedorov , John Lyle , Grace Lee , Lubomir Sebo , Duc Do , Robert Weber , Stephen Dudek
IPC分类号： A61K9/00 , A61K8/00 , A61F13/00 , C12Q1/68 , C12Q1/48 , C12Q1/02
CPC分类号： C07C49/255 , G01N21/6428 , G01N33/5306 , G01N2021/6432
摘要： Compositions, devices, systems and methods for reducing and/or preventing photo-induced damage of one or more reactants in an illuminated analytical reaction by addition of one or more photo-induced damage mitigating agents to the reaction mixture and allowing the reaction to proceed for a period that is less than a photo-induced damage threshold period.
摘要翻译：用于通过向反应混合物中加入一种或多种光诱导的损伤缓解剂来减少和/或防止一种或多种反应物在照明分析反应中的光诱导损伤的组合物，装置，系统和方法，并允许反应进行这个时间小于光致伤害阈值周期。

4. 发明申请

US20100136592A1 Photo-Induced Damage Mitigating Agents and Preparation and Methods of Use Thereof 有权
标题翻译：光诱导减伤剂及其制备及使用方法
公开(公告)号：US20100136592A1
公开(公告)日：2010-06-03
申请号：US12622375
申请日：2009-11-19
申请人： Xiangxu Kong , Gene Shen , Andrei Fedorov , John Lyle , Grace Lee , Lubomir Sebo , Duc Do , Robert Weber , Stephen Dudek
发明人： Xiangxu Kong , Gene Shen , Andrei Fedorov , John Lyle , Grace Lee , Lubomir Sebo , Duc Do , Robert Weber , Stephen Dudek
IPC分类号： C12Q1/48 , C12N9/00 , C12N11/00 , C12N9/12 , C12Q1/00 , C07H19/04 , C12N9/96 , C12M1/34 , C09K15/08
CPC分类号： C07C49/255 , G01N21/6428 , G01N33/5306 , G01N2021/6432
摘要： Compositions, devices, systems and methods for reducing and/or preventing photo-induced damage of one or more reactants in an illuminated analytical reaction by addition of one or more photo-induced damage mitigating agents to the reaction mixture and allowing the reaction to proceed for a period that is less than a photo-induced damage threshold period.
摘要翻译：用于通过向反应混合物中加入一种或多种光诱导的损伤缓解剂来减少和/或防止一种或多种反应物在照明分析反应中的光诱导损伤的组合物，装置，系统和方法，并允许反应进行这个时间小于光致伤害阈值期。

5. 发明申请

US20120052488A1 PHOTODAMAGE MITIGATION COMPOUNDS AND SYSTEMS 有权
标题翻译：光化学减轻化合物和体系
公开(公告)号：US20120052488A1
公开(公告)日：2012-03-01
申请号：US13208151
申请日：2011-08-11
申请人： Stephen Yue , Robert Weber , Xiangxu Kong , Andrei Fedorov , John Lyle
发明人： Stephen Yue , Robert Weber , Xiangxu Kong , Andrei Fedorov , John Lyle
IPC分类号： C12Q1/68 , C07D405/14 , C07C243/14 , C07C63/04 , C07C309/19
CPC分类号： C12Q1/6869 , C12N13/00 , C12Q1/25 , G01N33/52 , G01N33/54373 , G01N2333/91245 , G01N2333/916
摘要： Compositions, devices, systems and methods for reducing and/or preventing photo-induced damage of one or more reactants in an illuminated analytical reaction by addition of one or more photoprotective compounds to the reaction mixture and allowing the reaction to proceed for a period that is less than a photo-induced damage threshold period.
摘要翻译：用于通过向反应混合物中加入一种或多种光保护性化合物并允许反应进行一段时间，以减少和/或防止照明分析反应中的一种或多种反应物的光诱导损伤的组合物，装置，系统和方法小于光致伤害阈值期。

6. 发明授权

US08834847B2 Photodamage mitigation compounds and systems 有权
标题翻译：光损伤化合物和系统
公开(公告)号：US08834847B2
公开(公告)日：2014-09-16
申请号：US13208151
申请日：2011-08-11
申请人： Stephen Yue , Robert Weber , Xiangxu Kong , Andrei Fedorov , John Lyle
发明人： Stephen Yue , Robert Weber , Xiangxu Kong , Andrei Fedorov , John Lyle
IPC分类号： A61B5/00 , C12Q1/68 , C12Q1/25 , G01N33/52 , G01N33/543
CPC分类号： C12Q1/6869 , C12N13/00 , C12Q1/25 , G01N33/52 , G01N33/54373 , G01N2333/91245 , G01N2333/916
摘要： Compositions, devices, systems and methods for reducing and/or preventing photo-induced damage of one or more reactants in an illuminated analytical reaction by addition of one or more photoprotective compounds to the reaction mixture and allowing the reaction to proceed for a period that is less than a photo-induced damage threshold period.
摘要翻译：用于通过向反应混合物中加入一种或多种光保护性化合物并允许反应进行一段时间，以减少和/或防止照明分析反应中的一种或多种反应物的光诱导损伤的组合物，装置，系统和方法小于光致伤害阈值期。

7. 发明申请

US20080089029A1 Thermal Management Devices, Systems, and Methods 失效
标题翻译：热管理设备，系统和方法
公开(公告)号：US20080089029A1
公开(公告)日：2008-04-17
申请号：US11867070
申请日：2007-10-04
申请人： Stephane Launay , Andrei Fedorov , Yogendra Joshi
发明人： Stephane Launay , Andrei Fedorov , Yogendra Joshi
IPC分类号： H05K7/20 , G06F1/20
CPC分类号： G06F1/203 , F28F3/02 , F28F13/18 , G06F1/206 , H05K5/0213
摘要： Briefly described, embodiments of this disclosure include thermal management devices, systems, and methods, convection cooling devices, convection cooling systems, convection cooling methods, hybrid convection/desorption cooling devices, hybrid convection/desorption cooling systems, hybrid convection/desorption cooling methods, are disclosed.
摘要翻译：简要描述，本公开的实施例包括热管理装置，系统和方法，对流冷却装置，对流冷却系统，对流冷却方法，混合对流/解吸冷却装置，混合对流/解吸冷却系统，混合对流/解吸冷却方法，被披露。

8. 发明申请

US20050054208A1 Electrospray systems and methods 有权
标题翻译：电喷雾系统和方法
公开(公告)号：US20050054208A1
公开(公告)日：2005-03-10
申请号：US10930197
申请日：2004-08-31
申请人： Andrei Fedorov , F. Degertekin
发明人： Andrei Fedorov , F. Degertekin
IPC分类号： B01D59/44 , B01L3/02 , H01J49/00 , H01J49/04 , H01J49/10 , H01L21/302 , H01L21/461
CPC分类号： B05B17/0638 , B01L3/0268 , B01L2400/0439 , B05B5/025 , F23D11/32 , H01J49/0018 , H01J49/165
摘要： Electrospray systems, electrospray structures, removable electrospray structures, methods of operating electrospray systems, and methods of fabricating electrospray systems, are disclosed.
摘要翻译：公开了电喷雾系统，电喷雾结构，可移除电喷雾结构，操作电喷雾系统的方法以及制造电喷雾系统的方法。

9. 发明申请

US20080107935A1 INTEGRATED MICRO FUEL PROCESSOR AND FLOW DELIVERY INFRASTRUCTURE 有权
标题翻译：集成微型燃料加工器和流量输送基础设施
公开(公告)号：US20080107935A1
公开(公告)日：2008-05-08
申请号：US11854703
申请日：2007-09-13
申请人： F. Degertekin , Andrei Fedorov
发明人： F. Degertekin , Andrei Fedorov
IPC分类号： H01M8/06
CPC分类号： H01M8/0631
摘要： Apparatus for transporting a fluid, atomizers, reactors, integrated fuel processing apparatus, combinations thereof, methods of atomizing reactants, methods of moving fluids, methods of reverse-flow in a reactor, and combinations thereof, are provided. One exemplary apparatus for transporting a fluid, among others, includes: a channel for receiving a fluid; a sensor for determining an internal condition of the fluid in the channel; and a channel actuator in communication with the sensor for changing a cross-sectional area of the channel based on the internal condition, wherein the change in cross-sectional area controls a parameter selected from a pressure and a fluid flow.
摘要翻译：提供了用于输送流体的装置，雾化器，反应器，集成燃料处理装置，其组合，雾化反应物的方法，移动流体的方法，反应器中的逆流方法及其组合。一种用于运输流体的示例性装置，其中包括：用于接收流体的通道; 用于确定所述通道中的所述流体的内部状态的传感器; 以及与所述传感器连通的通道致动器，其基于所述内部条件改变所述通道的横截面面积，其中所述横截面积的变化控制从压力和流体流动中选择的参数。

10. 发明申请

US20070164216A1 Scanning ion probe systems and methods of use thereof 有权
标题翻译：扫描离子探针系统及其使用方法
公开(公告)号：US20070164216A1
公开(公告)日：2007-07-19
申请号：US11336137
申请日：2006-01-19
申请人： Andrei Fedorov
发明人： Andrei Fedorov
IPC分类号： H01J49/04 , G01N13/10
CPC分类号： H01J49/165 , G01Q30/02 , G01Q30/14 , H01J49/0004 , H01J49/0436
摘要： Briefly described, embodiments of this disclosure, among others, include scanning ion probe systems, methods of use thereof, scanning ion source systems, methods of use thereof, scanning ion probe mass spectrometry systems, methods of use thereof, methods of simultaneous ion analysis and imaging, and methods of simultaneous mass spectrometry and imaging.
摘要翻译：简而言之，本公开的实施例包括扫描离子探针系统，其使用方法，扫描离子源系统，其使用方法，扫描离子探针质谱系统，其使用方法，同时离子分析方法和成像和同时质谱法和成像方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式