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    • 1. 发明申请
    • DISPOSABLES FOR BLOOD TREATMENT, AND METHODS OF OPERATING THE SAME
    • 用于血液治疗的药物及其操作方法
    • WO2012175435A1
    • 2012-12-27
    • PCT/EP2012/061551
    • 2012-06-18
    • GAMBRO LUNDIA ABJANSSON, OlofHOLMER, MattiasNILSSON, EddieJÖNSSON, Lennart
    • JANSSON, OlofHOLMER, MattiasNILSSON, EddieJÖNSSON, Lennart
    • A61M1/30A61M1/36
    • A61M1/367A61M1/30A61M1/302A61M1/303A61M1/306A61M1/3621A61M2205/125A61M2205/128Y10T137/0318Y10T137/85986Y10T137/86035
    • A disposable for use in blood treatment comprises a blood treatment unit (8) and a pump arrangement (11) operable to pump blood through the blood treatment unit (8). The pump arrangement (11) comprises two membrane pumps (6, 7) connected in parallel on one side of the blood treatment unit (8). The disposable is operable in a single-needle mode, in which the pump arrangement (11) is operable to generate a pulsatile flow of blood through the blood treatment unit (8), and in a double-needle mode, in which the pump arrangement (11) is operable to generate an essentially continuous flow of blood through the blood treatment unit (8). The pump arrangement (11) is configured for connection to a supply system (1) of treatment fluid for the blood treatment unit (8) such that alternating flows of treatment fluid generated by the supply system (1) and supplied to the first and second membrane pumps (6, 7) causes the pump arrangement (11) to generate the desired flows of blood in the single-needle and double- needle modes. The treatment fluid may be used as motive fluid for displacing the blood in the membrane pumps (6, 7) and/or as control fluid for controlling opening and/or closing of upstream and downstream commutation valves (34, 35) in the membrane pumps (6, 7).
    • 用于血液处理的一次性用品包括血液处理单元(8)和可操作以将血液泵送通过血液处理单元(8)的泵装置(11)。 泵装置(11)包括在血液处理单元(8)的一侧上并联连接的两个膜泵(6,7)。 一次性可以单针模式操作,其中泵装置(11)可操作以通过血液处理单元(8)产生脉动血液流,并且在双针模式中,泵装置 (11)可操作以通过血液处理单元(8)产生基本上连续的血液流。 泵装置(11)构造成用于连接到用于血液处理单元(8)的处理流体的供应系统(1),使得由供应系统(1)产生并供应到第一和第二 膜泵(6,7)使泵装置(11)以单针和双针模式产生所需的血液流。 处理流体可以用作移动膜泵(6,7)中的血液的运动流体和/或用作控制膜泵中上游和下游换向阀(34,35)的打开和/或关闭的控制流体 (6,7)。
    • 2. 发明申请
    • MEMBRANE PUMP SYSTEM
    • 膜泵系统
    • WO2011045167A1
    • 2011-04-21
    • PCT/EP2010/064118
    • 2010-09-24
    • GAMBRO LUNDIA ABNILSSON, EddieJÖNSSON, LennartHOLMER, Mattias
    • NILSSON, EddieJÖNSSON, LennartHOLMER, Mattias
    • A61M1/10A61M1/16F04B43/06
    • A61M1/1639A61M1/1006A61M1/1037A61M1/106A61M1/16A61M2205/12F04B43/026F04B43/06
    • The present invention relates to a membrane pump and an apparatus comprising such a membrane pump. The membrane pump comprises a pumping chamber and a flexible member separating the pumping chamber into a first accumulation container and a second accumulation container. The flexible member is configured to be movable within the pumping chamber so as to vary a volume relationship between the first and second accumulation container. The second accumulation container is configured to receive an amount of working fluid to act on the flexible member and thus, in use, pump a first fluid from the first accumulation container. The first and the second accumulation container, each has an inlet opening for inlet of the respective fluid and an outlet opening for outlet of the respective fluid, the inlet opening being arranged on one side of the accumulation container and the outlet opening being arranged on the opposite side of the accumulation container. The flexible member is configured to show, when arranged in the pumping chamber and seen in a cross section along a plane extending through a pair of the inlet and outlet openings of the accumulation container, a thickness that is increased in a downstream direction.
    • 膜泵技术领域本发明涉及膜泵和包括这种膜泵的装置。 膜泵包括泵送室和将泵送室分离成第一积聚容器和第二积聚容器的柔性构件。 柔性构件被构造成在泵送室内可移动,以便改变第一和第二积聚容器之间的体积关系。 第二积聚容器构造成接收一定量的工作流体以作用在柔性构件上,因此在使用中从第一积聚容器泵送第一流体。 第一和第二蓄积容器各自具有用于各流体的入口的入口和用于各流体的出口的出口,入口开口布置在聚集容器的一侧上,出口开口布置在 积聚容器的相对侧。 柔性构件被构造成当布置在泵送室中并且沿着延伸穿过堆积容器的一对入口和出口开口的平面的横截面中看到时,其在下游方向上增加的厚度。
    • 3. 发明申请
    • BLOOD TREATMENT APPARATUS
    • 血液治疗装置
    • WO2009127626A1
    • 2009-10-22
    • PCT/EP2009/054408
    • 2009-04-14
    • GAMBRO LUNDIA ABJÖNSSON, LennartJANSSON, OlofHOLMER, MattiasNILSSON, Eddie
    • JÖNSSON, LennartJANSSON, OlofHOLMER, MattiasNILSSON, Eddie
    • A61M1/10A61M1/30
    • A61M1/30A61M1/1006A61M1/1037A61M1/106A61M1/1086A61M1/302A61M1/303A61M1/306A61M1/3626A61M2205/331
    • A proposed blood treatment apparatus includes : a blood treatment unit (8), at least one fluid pump (14, 15) and at least one blood pump (1a, 1b). The blood treatment unit (8) is configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid. The fluid pump(s) (14, 15) is(are) configured to pass blood treatment fluid through the blood treatment unit (8). The blood pump(s) ( 1a, 1b) is(are) configured to extract untreated blood from a blood source (S), pass extracted blood through the blood treatment unit (8) and deliver treated blood to a target vessel (T). Additionally, at least one of the fluid pumps (14, 15) is configured to control the operation of at least one blood pump (1a, 1b) via the blood treatment fluid. Moreover, at least one of the blood pumps (1a, 1b) is integrated into a joint apparatus element (D), which includes the blood treatment unit (8). Thus, this blood pump and the unit (8) may be mounted as well as be discarded jointly.
    • 提出的血液处理装置包括:血液处理单元(8),至少一个流体泵(14,15)和至少一个血液泵(1a,1b)。 血液处理单元(8)构成为能够接收未经处理的血液和新鲜的血液处理液,并且排出经处理的血液和使用的血液处理液。 流体泵(14,15)被配置为使血液处理流体通过血液处理单元(8)。 血液泵(1a,1b)被构造成从血液源(S)中提取未经处理的血液,通过血液处理单元(8)提取血液并将处理的血液输送到目标血管(T) 。 此外,流体泵(14,15)中的至少一个构造成经由血液处理流体来控制至少一个血液泵(1a,1b)的操作。 此外,血液泵(1a,1b)中的至少一个被集成到包括血液处理单元(8)的接合装置元件(D)中。 因此,该血液泵和单元(8)可以被安装并被联合丢弃。
    • 5. 发明申请
    • HEAT EXCHANGER AND METHOD FOR HEAT EXCHANGING
    • 热交换器和换热器的方法
    • WO2010040827A1
    • 2010-04-15
    • PCT/EP2009/063169
    • 2009-10-09
    • GAMBRO LUNDIA ABJÖNSSON, LennartSTERNBY, JanNILSSON, Eddie
    • JÖNSSON, LennartSTERNBY, JanNILSSON, Eddie
    • A61M1/34
    • A61M1/3462A61M1/3621A61M5/44A61M2205/366F28D9/0075F28D9/0087F28D9/0093
    • The present invention relates to a method for exchanging heat between a effluent fluid (4) and a blood fluid and a heat exchanger (11) for heat exchange. The heat exchanger comprises a first and a second fluid circuit (19, 20) extending through the heat exchanger. The heat exchanger further comprises a stack of fluid plates (12, 13, 40) and a membrane (16) arranged between each of the fluid plates (12, 13, 40) where one interspace is formed between each fluid plate and membrane. The first and the second fluid circuit (19, 20) is each constituted by a passage extending through the fluid plates and membranes and along the fluid plates and membranes in at least two interspaces (17, 18). According to the method for heat exchanging an effluent fluid (4) is passed through the first fluid circuit (19) and a blood fluid is passed through the second fluid circuit (20) such that the effluent fluid (4) is passed along one side of a membrane (16) and simultaneously the blood fluid is passed along the other side of the membrane (16). Heat is thus exchanged between the effluent fluid (4) and the blood fluid over the membrane (16).
    • 本发明涉及一种用于在流出液(4)和血液流体之间进行热交换的方法和用于热交换的热交换器(11)。 热交换器包括延伸穿过热交换器的第一和第二流体回路(19,20)。 热交换器还包括一组流体板(12,13,40)和布置在每个流体板(12,13,40)之间的膜(16),其中在每个流体板和膜之间形成一个间隙。 第一和第二流体回路(19,20)各自由在至少两个间隙(17,18)中延伸穿过流体板和膜并沿着流体板和膜延伸的通道构成。 根据用于热交换的方法,流出物流体(4)通过第一流体回路(19),血液流过第二流体回路(20),使得流出物流体(4)沿着一侧 的膜(16),并且同时使血液流体沿膜(16)的另一侧通过。 因此,在流出液(4)和膜(16)之间的血液流体之间交换热量。
    • 6. 发明申请
    • HEAT EXCHANGER AND METHOD FOR HEAT EXCHANGING
    • 热交换器和换热器的方法
    • WO2010040824A1
    • 2010-04-15
    • PCT/EP2009/063159
    • 2009-10-09
    • GAMBRO LUNDIA ABJÖNSSON, LennartSTERNBY, JanNILSSON, Eddie
    • JÖNSSON, LennartSTERNBY, JanNILSSON, Eddie
    • A61M1/34
    • A61M1/3462A61M1/3621A61M5/44A61M2205/366F28D9/0075F28D9/0087F28D9/0093
    • The present invention relates to a method for exchanging heat between an effluent fluid (4) and a treatment fluid (5, 7, 9) and a heat exchanger (11) for heat exchange as well as an arrangement and a kit comprising a heat exchanger. The heat exchanger comprises a first and a second fluid circuit (19, 20) extending through the heat exchanger. The heat exchanger further comprises a stack of fluid plates (12, 13, 40) and a membrane (16) arranged between each of the fluid plates (12, 13, 40) where one interspace is formed between each fluid plate and membrane. The first and the second fluid circuit (19, 20) is each constituted by a passage extending through the fluid plates and membranes and along the fluid plates and membranes in at least two interspaces (17, 18). According to the method for heat exchanging an effluent fluid (4) is passed through the first fluid circuit (19) and a treatment fluid (5, 7, 9) is passed through the second fluid circuit (20) such that the effluent fluid (4) is passed along one side of a membrane (16) and simultaneously the treatment fluid (5, 7, 9) is passed along the other side of the membrane (16). Heat is thus exchanged between the effluent fluid (4) and the treatment fluid (5, 7, 9) over the membrane (16).
    • 本发明涉及一种用于在流出物流体(4)和处理流体(5,7,9)和用于热交换的热交换器(11)之间进行热交换的方法,以及包括热交换器 。 热交换器包括延伸穿过热交换器的第一和第二流体回路(19,20)。 热交换器还包括一组流体板(12,13,40)和布置在每个流体板(12,13,40)之间的膜(16),其中在每个流体板和膜之间形成一个间隙。 第一和第二流体回路(19,20)各自由在至少两个间隙(17,18)中延伸穿过流体板和膜并沿着流体板和膜延伸的通道构成。 根据用于热交换的方法,流出物流体(4)通过第一流体回路(19),并且处理流体(5,7,9)通过第二流体回路(20),使得流出物流体 4)沿着膜(16)的一侧通过,同时处理流体(5,7,9)沿膜(16)的另一侧通过。 因此,在流出液(4)和膜(16)之间的处理流体(5,7,9)之间交换热量。
    • 10. 发明申请
    • HEAT EXCHANGER AND METHOD FOR HEAT EXCHANGING
    • 热交换器和换热器的方法
    • WO2010040819A1
    • 2010-04-15
    • PCT/EP2009/063148
    • 2009-10-09
    • GAMBRO LUNDIA ABJÖNSSON, LennartSTERNBY, JanNILSSON, Eddie
    • JÖNSSON, LennartSTERNBY, JanNILSSON, Eddie
    • A61M1/36A61M5/44F28D9/00
    • A61M1/3462A61M1/3621A61M5/44A61M2205/366F28D9/0075F28D9/0087F28D9/0093
    • The present invention relates to a method for exchanging heat between a primary fluid (W) and a secondary fluid 5 (X) and a heat exchanger (11) for heat exchange as well as an arrangement and a kit comprising a heat exchanger. The heat exchanger comprises a first and a second fluid circuit (19, 20) extending through the heat exchanger. The heat exchanger further comprises a stack of fluid plates (12, 13, 40) and a membrane (16) arranged between each of the fluid plates (12, 13, 40) where one interspace is formed between each fluid plate and membrane. The first and the second fluid circuit (19, 20) is each constituted by a passage extending through the fluid plates and membranes and along the fluid plates and membranes in at least two interspaces (17, 18). According to the method for heat exchanging a primary fluid (W) is passed through the first fluid circuit (19) and a secondary fluid (X) is passed through the second fluid circuit (20) such that the primary fluid (W) is passed along one side of a membrane (16) and simultaneously the secondary fluid (X) is passed along the other side of the membrane (16). Heat is thus exchanged between the primary fluid (W) and the secondary fluid (X) over the membrane (16).
    • 本发明涉及一种用于在一次流体(W)和二次流体5(X)和用于热交换的热交换器(11)之间进行热交换的方法以及包括热交换器的装置和套件。 热交换器包括延伸穿过热交换器的第一和第二流体回路(19,20)。 热交换器还包括一组流体板(12,13,40)和布置在每个流体板(12,13,40)之间的膜(16),其中在每个流体板和膜之间形成一个间隙。 第一和第二流体回路(19,20)各自由在至少两个间隙(17,18)中延伸穿过流体板和膜并沿着流体板和膜延伸的通道构成。 根据热交换方法,使第一流体(W)通过第一流体回路(19),并且次级流体(X)通过第二流体回路(20),使得主流体(W)通过 沿着膜(16)的一侧,并且同时使第二流体(X)沿膜(16)的另一侧通过。 因此,在膜(16)之间的主要流体(W)和次级流体(X)之间交换热量。