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1. 发明申请

WO2011161054A1 BLOOD ACCESS DEVICE 审中-公开
标题翻译：血液接入装置
公开(公告)号：WO2011161054A1
公开(公告)日：2011-12-29
申请号：PCT/EP2011/060230
申请日：2011-06-20
申请人： GAMBRO LUNDIA AB , EKDAHL, Olof , ZANINI, Marco , HANSSON, Per , NILSSON, Eddie , JANSSON, Olof , JÖNSSON, Lennart
发明人： EKDAHL, Olof , ZANINI, Marco , HANSSON, Per , NILSSON, Eddie , JANSSON, Olof , JÖNSSON, Lennart
IPC分类号： A61M25/06 , A61M39/28
CPC分类号： A61M5/168 , A61M1/3621 , A61M1/3653 , A61M1/3655 , A61M1/3656 , A61M1/3661 , A61M5/158 , A61M5/16854 , A61M25/02 , A61M25/0637 , A61M39/281 , A61M39/284 , A61M2005/1586 , A61M2025/024
摘要： A blood access device comprises a fluid conduit (50) configured to convey a flow of fluid to a target vessel (2), a second lever element (20) pivotally and resiliently connected to a first lever element (10) such that it may move from a first position (P1) to a second position. A biasing force is exerted on the second lever element (20) for moving it from the first position (P1) to the second position, and a blocking member may be activated by the second lever element (20), such that a flow of fluid is decreased when the second lever element (20) is moved from the first position (P1) to the second position. The lever elements (10, 20) are configured to be fixed to the target vessel (2) when the second lever element (20) is in the first position (P1), and the second lever element (20) moves to the second position (P2) and activates the blocking member (14) if the fixation is at least partially lost. A related blood treatment apparatus is also described.
摘要翻译：血液进入装置包括被配置为将流体流传送到目标血管（2）的流体导管（50），枢转地并弹性地连接到第一杠杆元件（10）的第二杠杆元件（20），使得其可以移动从第一位置（P1）到第二位置。偏压力施加在第二杠杆元件20上，用于将其从第一位置（P1）移动到第二位置，并且阻挡构件可以由第二杠杆元件（20）启动，使得流体流动当第二杠杆元件（20）从第一位置（P1）移动到第二位置时减小。杠杆元件（10,20）构造成当第二杠杆元件（20）处于第一位置（P1）时固定到目标船舶（2），并且第二杠杆元件（20）移动到第二位置（P2）并且如果固定件至少部分损失则启动阻挡构件（14）。还描述了一种相关的血液处理装置。

2. 发明申请

WO2012175435A1 DISPOSABLES FOR BLOOD TREATMENT, AND METHODS OF OPERATING THE SAME 审中-公开
标题翻译：用于血液治疗的药物及其操作方法
公开(公告)号：WO2012175435A1
公开(公告)日：2012-12-27
申请号：PCT/EP2012/061551
申请日：2012-06-18
申请人： GAMBRO LUNDIA AB , JANSSON, Olof , HOLMER, Mattias , NILSSON, Eddie , JÖNSSON, Lennart
发明人： JANSSON, Olof , HOLMER, Mattias , NILSSON, Eddie , JÖNSSON, Lennart
IPC分类号： A61M1/30 , A61M1/36
CPC分类号： A61M1/367 , A61M1/30 , A61M1/302 , A61M1/303 , A61M1/306 , A61M1/3621 , A61M2205/125 , A61M2205/128 , Y10T137/0318 , Y10T137/85986 , Y10T137/86035
摘要： A disposable for use in blood treatment comprises a blood treatment unit (8) and a pump arrangement (11) operable to pump blood through the blood treatment unit (8). The pump arrangement (11) comprises two membrane pumps (6, 7) connected in parallel on one side of the blood treatment unit (8). The disposable is operable in a single-needle mode, in which the pump arrangement (11) is operable to generate a pulsatile flow of blood through the blood treatment unit (8), and in a double-needle mode, in which the pump arrangement (11) is operable to generate an essentially continuous flow of blood through the blood treatment unit (8). The pump arrangement (11) is configured for connection to a supply system (1) of treatment fluid for the blood treatment unit (8) such that alternating flows of treatment fluid generated by the supply system (1) and supplied to the first and second membrane pumps (6, 7) causes the pump arrangement (11) to generate the desired flows of blood in the single-needle and double- needle modes. The treatment fluid may be used as motive fluid for displacing the blood in the membrane pumps (6, 7) and/or as control fluid for controlling opening and/or closing of upstream and downstream commutation valves (34, 35) in the membrane pumps (6, 7).
摘要翻译：用于血液处理的一次性用品包括血液处理单元（8）和可操作以将血液泵送通过血液处理单元（8）的泵装置（11）。泵装置（11）包括在血液处理单元（8）的一侧上并联连接的两个膜泵（6,7）。一次性可以单针模式操作，其中泵装置（11）可操作以通过血液处理单元（8）产生脉动血液流，并且在双针模式中，泵装置（11）可操作以通过血液处理单元（8）产生基本上连续的血液流。泵装置（11）构造成用于连接到用于血液处理单元（8）的处理流体的供应系统（1），使得由供应系统（1）产生并供应到第一和第二膜泵（6,7）使泵装置（11）以单针和双针模式产生所需的血液流。处理流体可以用作移动膜泵（6,7）中的血液的运动流体和/或用作控制膜泵中上游和下游换向阀（34,35）的打开和/或关闭的控制流体（6,7）。

3. 发明申请

WO2011076511A1 BLOOD TREATMENT DEVICE FOR A DIALYSIS MACHINE 审中-公开
标题翻译：用于透析机的血液处理装置
公开(公告)号：WO2011076511A1
公开(公告)日：2011-06-30
申请号：PCT/EP2010/068214
申请日：2010-11-25
申请人： GAMBRO LUNDIA AB , NILSSON, Eddie , JÖNSSON, Lennart , JANSSON, Olof
发明人： NILSSON, Eddie , JÖNSSON, Lennart , JANSSON, Olof
IPC分类号： A61M1/30 , A61M1/36
CPC分类号： A61M1/30 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/302 , A61M1/3621 , A61M2205/128
摘要： A blood treatment device comprising a blood treatment unit (20) with a valve (6) configured to move between a first position and a second position, for opening and closing multiple sections in a blood withdrawal line such that double-needle dialysis is achieved. Alternatively, single needle dialysis is achieved by moving the valve between two specific positions. Still alternatively, it is also possible to achieve either double-needle or single-needle dialysis, as selected by an operator, by moving the valve between four positions.
摘要翻译：一种血液处理装置，包括具有构造成在第一位置和第二位置之间移动的阀（6）的血液处理单元（20），用于打开和关闭抽血管线中的多个部分，从而实现双针透析。或者，通过在两个特定位置之间移动阀来实现单针透析。或者，也可以通过在四个位置之间移动阀来实现由操作者选择的双针或单针透析。

4. 发明申请

WO2009127626A1 BLOOD TREATMENT APPARATUS 审中-公开
标题翻译：血液治疗装置
公开(公告)号：WO2009127626A1
公开(公告)日：2009-10-22
申请号：PCT/EP2009/054408
申请日：2009-04-14
申请人： GAMBRO LUNDIA AB , JÖNSSON, Lennart , JANSSON, Olof , HOLMER, Mattias , NILSSON, Eddie
发明人： JÖNSSON, Lennart , JANSSON, Olof , HOLMER, Mattias , NILSSON, Eddie
IPC分类号： A61M1/10 , A61M1/30
CPC分类号： A61M1/30 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1086 , A61M1/302 , A61M1/303 , A61M1/306 , A61M1/3626 , A61M2205/331
摘要： A proposed blood treatment apparatus includes : a blood treatment unit (8), at least one fluid pump (14, 15) and at least one blood pump (1a, 1b). The blood treatment unit (8) is configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid. The fluid pump(s) (14, 15) is(are) configured to pass blood treatment fluid through the blood treatment unit (8). The blood pump(s) ( 1a, 1b) is(are) configured to extract untreated blood from a blood source (S), pass extracted blood through the blood treatment unit (8) and deliver treated blood to a target vessel (T). Additionally, at least one of the fluid pumps (14, 15) is configured to control the operation of at least one blood pump (1a, 1b) via the blood treatment fluid. Moreover, at least one of the blood pumps (1a, 1b) is integrated into a joint apparatus element (D), which includes the blood treatment unit (8). Thus, this blood pump and the unit (8) may be mounted as well as be discarded jointly.
摘要翻译：提出的血液处理装置包括：血液处理单元（8），至少一个流体泵（14,15）和至少一个血液泵（1a，1b）。血液处理单元（8）构成为能够接收未经处理的血液和新鲜的血液处理液，并且排出经处理的血液和使用的血液处理液。流体泵（14,15）被配置为使血液处理流体通过血液处理单元（8）。血液泵（1a，1b）被构造成从血液源（S）中提取未经处理的血液，通过血液处理单元（8）提取血液并将处理的血液输送到目标血管（T）。此外，流体泵（14,15）中的至少一个构造成经由血液处理流体来控制至少一个血液泵（1a，1b）的操作。此外，血液泵（1a，1b）中的至少一个被集成到包括血液处理单元（8）的接合装置元件（D）中。因此，该血液泵和单元（8）可以被安装并被联合丢弃。

5. 发明申请

WO2008140395A1 PRESSURE SENSING DEVICE AND USE OF THE SAME IN A CONNECTING STRUCTURE 审中-公开
标题翻译：压力传感装置及其在连接结构中的应用
公开(公告)号：WO2008140395A1
公开(公告)日：2008-11-20
申请号：PCT/SE2008/050475
申请日：2008-04-25
申请人： GAMBRO LUNDIA AB , JÖNSSON, Lennart , JANSSON, Olof , NILSSON, Eddie
发明人： JÖNSSON, Lennart , JANSSON, Olof , NILSSON, Eddie
IPC分类号： A61M1/36 , G01L7/08
CPC分类号： A61M1/3639 , A61M1/3627 , A61M1/3641
摘要： A pressure sensing device (1) adapted for having a liquid flowing there through and for sensing the pressure of said liquid. The device has a casing (2) being fluid-tightly divided into a first (3) and a second chamber (4) by a flexible, impermeable wall (5). The first chamber (3) has a first opening (6) for the liquid, said opening being placed at the lower part of the chamber (3), and a second opening (7) for the liquid, said opening being placed at the top of the first chamber (3). The second chamber (4) has a measuring port (8), which is connectable to a pressure transducer (9) for bringing the second chamber (4) into gas-tight communication with the pressure transducer (9). The device has a first orifice (10) for the liquid into/out of the device (1), which orifice is placed at the upper part of the device at a higher level than the second opening (7). A first channel (11) is connecting the first orifice (10) with the first opening (6). A second orifice (12) for the liquid out of/into the device (1) is placed at the lower part of the device at a lower level than the first opening (6). A second channel (13) is connecting the second opening (7) with the second orifice (12). In a first embodiment the highest level of the first chamber (3) is at the same level as or at a higher level than the highest level of the second channel (13). Use of such a pressure sensing device in a connecting structure for an extracorporeal blood treatment machine is also included.
摘要翻译：一种压力感测装置（1），适于使液体在其上流动并感测所述液体的压力。该装置具有通过柔性不渗透壁（5）流体密封地分成第一（3）和第二室（4）的壳体（2）。第一室（3）具有用于液体的第一开口（6），所述开口设置在室（3）的下部，以及用于液体的第二开口（7），所述开口位于顶部的第一室（3）。第二室（4）具有可连接到压力传感器（9）的测量口（8），用于使第二室（4）与压力传感器（9）气密连通。该装置具有用于液体进出装置（1）的第一孔口（10），该孔口以比第二开口（7）更高的水平位于装置的上部。第一通道（11）将第一孔口（10）与第一开口（6）连接。用于液体排出/进入装置（1）的第二孔口（12）以比第一开口（6）更低的水平位于装置的下部。第二通道（13）将第二开口（7）与第二孔（12）连接。在第一实施例中，第一腔室（3）的最高水平处于与第二通道（13）的最高水平相同的水平或处于比第二通道（13）的最高水平更高的水平。还包括在体外血液处理机的连接结构中使用这种压力感测装置。

6. 发明申请

WO2009127624A3 BLOOD TREATMENT APPARATUS 审中-公开
公开(公告)号：WO2009127624A3
公开(公告)日：2009-10-22
申请号：PCT/EP2009/054406
申请日：2009-04-14
申请人： GAMBRO LUNDIA AB , JÖNSSON, Lennart , JANSSON, Olof , HOLMER, Mattias , STERNBY, Jan , NILSSON, Anders , HANSSON, Per
发明人： JÖNSSON, Lennart , JANSSON, Olof , HOLMER, Mattias , STERNBY, Jan , NILSSON, Anders , HANSSON, Per
IPC分类号： A61M1/10 , A61M1/16 , A61M1/30 , A61M1/34
摘要： A proposed blood treatment apparatus includes : a blood treatment unit (8), a pair of fluid pumps (14, 15) and a pair of blood pumps (1a, 1b). The blood treatment unit (8) is configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid. The fluid pumps (14, 15) are configured to pass blood treatment fluid through the blood treatment unit (8). The blood pumps (1a, 1b) are configured to extract untreated blood from a blood source (S), pass extracted blood through the blood treatment unit (8) and deliver treated blood to a target vessel (T). Additionally, the fluid pumps (14, 15) are configured to control the operation of the blood pumps (1a, 1b) via the blood treatment fluid. Moreover, a flow control means (16a) is configured to control a trans- membrane flow between the blood side (8B) and the a fluid side (8F) of the blood treatment unit (8). Hence, for instance ultrafiltration can be adjusted to a desired level in a very straightforward manner.

7. 发明申请

WO2011161064A1 PREPARATION OF MEDICAL SOLUTIONS FROM POWDERY MATERIAL 审中-公开
标题翻译：从粉末材料制备医疗解决方案
公开(公告)号：WO2011161064A1
公开(公告)日：2011-12-29
申请号：PCT/EP2011/060255
申请日：2011-06-20
申请人： GAMBRO LUNDIA AB , JANSSON, Olof , JÖNSSON, Lennart , LINDEN, Torbjörn , STERNBY, Jan , TRYGGVASON, Ragnar , WIESLANDER, Anders
发明人： JANSSON, Olof , JÖNSSON, Lennart , LINDEN, Torbjörn , STERNBY, Jan , TRYGGVASON, Ragnar , WIESLANDER, Anders
IPC分类号： A61J1/20 , A61M1/16
CPC分类号： A61J1/20 , A61J1/2093 , A61M1/1656 , A61M1/1666 , A61M1/1668 , A61M1/167 , A61M1/287 , B65D31/14 , B65D81/18 , B65D81/20 , B65D81/2007 , B65D81/2023 , B65D81/2046
摘要： A package has a transport/storage state for storing powdery material which is to be mixed with a solvent to form a medical solution, e.g. for use in dialysis treatment. The package comprises a compartment (6) which is at least partially defined by two opposing wall portions, and a connector (10). In the transport/storage state, the compartment contains the powdery material in the form of at least two distinct sets (2A-2D) of powdery material of different compositions, where the opposing wall portions are brought into engagement with the powdery material so as to immobilize the sets of powdery material (2A-2D). When used for preparation of the medical solution, a fluid is selectively admitted into the package via the connector (10) so as to expand the compartment (6) and enable mixing of the sets (2A-2D) of powdery material with the solvent in the compartment (6).
摘要翻译：包装具有用于储存待与溶剂混合以形成医用溶液的粉末状材料的运输/储存状态，用于透析治疗。该包装件包括至少部分地由两个相对的壁部分限定的隔室（6）和连接器（10）。在运输/储存状态下，隔室含有至少两种不同组成的粉末材料组（2A-2D）形式的粉状材料，其中相对的壁部分与粉末材料接合，以便固定一组粉状材料（2A-2D）。当用于制备医用溶液时，通过连接器（10）将流体选择性地进入包装中，以便使隔室（6）膨胀，并使粉末材料组（2A-2D）与溶剂的组合隔室（6）。

8. 发明申请

WO2003066135A1 METHOD AND APPARATUS FOR DETERMINING ACCESS FLOW 审中-公开
标题翻译：用于确定访问流的方法和装置
公开(公告)号：WO2003066135A1
公开(公告)日：2003-08-14
申请号：PCT/IB2002/004537
申请日：2002-10-31
申请人： GAMBRO LUNDIA AB , BENE, Bernard , GOUX, Nicolas , HANSSON, Per , HERTZ, Thomas , JANSSON, Olof , PERSSON, Roland , STERNBY, Jan , ASBRINK, Perry
发明人： BENE, Bernard , GOUX, Nicolas , HANSSON, Per , HERTZ, Thomas , JANSSON, Olof , PERSSON, Roland , STERNBY, Jan , ASBRINK, Perry
IPC分类号： A61M1/16
CPC分类号： A61M1/30 , A61M1/16 , A61M1/1605 , A61M1/1617 , A61M1/3656 , A61M2202/0498 , A61M2205/13 , A61M2205/15 , A61M2205/3317 , A61M2205/3324 , A61M2205/50 , A61M2230/65
摘要： A method and apparatus for determining a fluid flow rate in a blood access having an upstream position and a downstream position using a blood treatment apparatus including a blood treatment unit having a semi permeable membrane delimiting a first chamber through which blood removed from said blood access passes and a second chamber through which dialysis liquid passes, an arterial line and a venous line, connected to an inlet and an outlet of the first chamber respectively. The method for determining the fluid flow rate involves measurement of the post dialyzer concentration or conductivity before and after a flow reversal. The invention further involves a method for checking the operating configuration of the arterial and venous lines of the blood treatment apparatus.
摘要翻译：一种用于使用血液处理设备来确定具有上游位置和下游位置的血液通路中的流体流量的方法和装置，所述血液处理设备包括血液处理单元，所述血液处理单元具有限定从所述血液存取通过的血液通过所述血液通过的第一室的半透膜以及透析液通过的第二室，分别连接到第一室的入口和出口的动脉线和静脉管。用于确定流体流速的方法涉及在逆流之前和之后测量后透析器浓度或电导率。本发明还涉及一种用于检查血液处理装置的动脉和静脉线的操作构造的方法。

9. 发明申请

WO2005035023A1 A DEVICE FOR CARRYING OUT A PERITONEAL DIALYSIS TREATMENT 审中-公开
标题翻译：执行腹膜透析治疗的手段
公开(公告)号：WO2005035023A1
公开(公告)日：2005-04-21
申请号：PCT/SE2004/001467
申请日：2004-10-13
申请人： GAMBRO LUNDIA AB , JANSSON, Olof , BERNARD, Pascal , DURAND, Pierre-Yves , HOBRO, Sture , PERSSON, Eva , THELL, Bengt-Olov
发明人： JANSSON, Olof , BERNARD, Pascal , DURAND, Pierre-Yves , HOBRO, Sture , PERSSON, Eva , THELL, Bengt-Olov
IPC分类号： A61M1/28
CPC分类号： A61M1/28 , A61M1/1613 , A61M1/281 , A61M1/282
摘要： The invention concerns a device and a method for a peritoneal dialysis treatment in several cycles. A cycler (1) controlled by a processor (31) fills the abdominal cavity with dialysis fluid, and drains the abdominal cavity. A sensor (37) senses a variable related to the draining of the dialysis fluid. The draining is interrupted when the variable reaches a breakpoint at which the variable is radically changed, thereby leaving the residual volume.
摘要翻译：本发明涉及用于在几个周期中进行腹膜透析治疗的装置和方法。由处理器（31）控制的循环仪（1）用透析液填充腹腔，并排出腹腔。传感器（37）感测与透析液排出相关的变量。当变量到达变量发生彻底改变的断点时，排水中断，从而留下剩余体积。

10. 发明申请

WO2012175354A1 DIALYSIS PRECURSOR COMPOSITION 审中-公开
标题翻译： DIALYSIS前身组成
公开(公告)号：WO2012175354A1
公开(公告)日：2012-12-27
申请号：PCT/EP2012/060971
申请日：2012-06-11
申请人： GAMBRO LUNDIA AB , JANSSON, Olof , LINDEN, Torbjörn , WIESLANDER, Anders
发明人： JANSSON, Olof , LINDEN, Torbjörn , WIESLANDER, Anders
IPC分类号： A61K9/00 , A61K31/185 , A61K31/7004 , A61K33/10
CPC分类号： A61K33/10 , A61K9/0029 , A61K9/0095 , A61K9/08 , A61K31/185 , A61K31/194 , A61K31/7004 , A61K33/14 , A61M1/1654 , B65B1/00 , B65B29/06 , A61K2300/00
摘要： The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consists of powder components comprising sodium chloride, at least one dry acid and at least one calcium salt, and optionally potassium salt, magnesium salt, and glucose. According to the invention said at least one calcium salt and said optional glucose, are present as anhydrous components in said dialysis acid precursor composition.
摘要翻译：本发明涉及一种透析酸前体组合物，用于制备透析酸浓缩液，并与水和含碳酸氢盐的浓缩液混合成即用型透析溶液。所述透析酸前体组合物由包含氯化钠，至少一种干酸和至少一种钙盐，以及任选的钾盐，镁盐和葡萄糖的粉末组分组成。根据本发明，所述至少一种钙盐和任选的葡萄糖以所述透析酸前体组合物中的无水组分存在。

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