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    • 3. 发明申请
    • COMPOSITE STRUCTURE AND PROCESS FOR PRODUCING THE SAME
    • 复合结构及其制造方法
    • US20090173439A1
    • 2009-07-09
    • US12401219
    • 2009-03-10
    • Fumihiro HAYASHIYasuhiro OkudaMotomi Nakata
    • Fumihiro HAYASHIYasuhiro OkudaMotomi Nakata
    • B32B37/02
    • A61F2/07A61F2/89A61F2002/072A61F2002/075
    • A composite structure comprising two polytetrafluoroethylene porous layers and a framework structural member having a plurality of gaps or openings, the framework structural member being disposed between the two polytetrafluoroethylene porous layers, wherein the composite structure is structured such that the polytetrafluoroethylene porous layers are united together by being adhered with each other through the gaps or openings of the framework structural member and such that the respective polytetrafluoroethylene porous layers (A1) and (A2) are united with the framework structural member closely along the surfaces of the respective constituent elements of the framework structural member in such a manner as to wrap the respective elements. The method of manufacturing the composite structure is characterized in that it includes a step of applying pressure through a mass of fine particles.
    • 包括两个聚四氟乙烯多孔层的复合结构和具有多个间隙或开口的框架结构构件,所述框架结构构件设置在所述两个聚四氟乙烯多孔层之间,其中所述复合结构被构造成使得所述聚四氟乙烯多孔层通过 通过框架结构构件的间隙或开口彼此粘合,并且使得相应的聚四氟乙烯多孔层(A1)和(A2)与框架结构构件紧密地沿着框架结构的各个构成元件的表面结合 构件以包裹各个元件的方式。 制造复合结构体的方法的特征在于,其包括通过大量微粒施加压力的步骤。
    • 4. 发明授权
    • Composite structure and process for producing the same
    • 复合结构及其制造方法
    • US08506750B2
    • 2013-08-13
    • US12401219
    • 2009-03-10
    • Fumihiro HayashiYasuhiro OkudaMotomi Nakata
    • Fumihiro HayashiYasuhiro OkudaMotomi Nakata
    • B32B37/00
    • A61F2/07A61F2/89A61F2002/072A61F2002/075
    • A composite structure comprising two polytetrafluoroethylene porous layers and a framework structural member having a plurality of gaps or openings, the framework structural member being disposed between the two polytetrafluoroethylene porous layers, wherein the composite structure is structured such that the polytetrafluoroethylene porous layers are united together by being adhered with each other through the gaps or openings of the framework structural member and such that the respective polytetrafluoroethylene porous layers (A1) and (A2) are united with the framework structural member closely along the surfaces of the respective constituent elements of the framework structural member in such a manner as to wrap the respective elements. The method of manufacturing the composite structure is characterized in that it includes a step of applying pressure through a mass of fine particles.
    • 包括两个聚四氟乙烯多孔层的复合结构和具有多个间隙或开口的框架结构构件,所述框架结构构件设置在所述两个聚四氟乙烯多孔层之间,其中所述复合结构被构造成使得所述聚四氟乙烯多孔层通过 通过框架结构构件的间隙或开口彼此粘合,并且使得相应的聚四氟乙烯多孔层(A1)和(A2)与框架结构构件紧密地沿着框架结构的各个构成元件的表面结合 构件以包裹各个元件的方式。 制造复合结构体的方法的特征在于,其包括通过大量微粒施加压力的步骤。
    • 5. 发明申请
    • Composite structure and process for producing the same
    • 复合结构及其制造方法
    • US20070173917A1
    • 2007-07-26
    • US10590739
    • 2004-02-27
    • Fumihiro HayashiYasuhiro OkudaMotomi Nakata
    • Fumihiro HayashiYasuhiro OkudaMotomi Nakata
    • A61F2/06
    • A61F2/07A61F2/89A61F2002/072A61F2002/075
    • A composite structure comprising two polytetrafluoroethylene porous layers and a framework structural member having a plurality of gaps or openings, the framework structural member being disposed between the two polytetrafluoroethylene porous layers, wherein the composite structure is structured such that the polytetrafluoroethylene porous layers are united together by being adhered with each other through the gaps or openings of the framework structural member and such that the respective polytetrafluoroethylene porous layers (A1) and (A2) are united with the framework structural member closely along the surfaces of the respective constituent elements of the framework structural member in such a manner as to wrap the respective elements. The method of manufacturing the composite structure is characterized in that it includes a step of applying pressure through a mass of fine particles.
    • 包括两个聚四氟乙烯多孔层的复合结构和具有多个间隙或开口的框架结构构件,所述框架结构构件设置在所述两个聚四氟乙烯多孔层之间,其中所述复合结构被构造成使得所述聚四氟乙烯多孔层通过 通过框架结构构件的间隙或开口彼此粘合,并且使得相应的聚四氟乙烯多孔层(A 1)和(A 2)与框架结构构件紧密地沿着相应的构成元件的表面 框架结构构件以包裹各个元件的方式。 制造复合结构体的方法的特征在于,其包括通过大量微粒施加压力的步骤。
    • 10. 发明授权
    • TRAF family molecules, polynucleotides encoding them, and antibodies against them
    • TRAF家族分子,编码它们的多核苷酸和针对它们的抗体
    • US06426403B1
    • 2002-07-30
    • US09138277
    • 1998-08-18
    • Motomi NakataHiroyasu NakanoHideo YagitaKo Okumura
    • Motomi NakataHiroyasu NakanoHideo YagitaKo Okumura
    • C07K1452
    • C07K14/70503A61K38/00C07K14/715C07K14/7151
    • This invention relates to a TRAF family molecule, a polynucleotide encoding the molecules, an antibody against the molecules, and an antisense polynucleotide of the molecule. Employing an oligo-DNA primer capable of amplifying the most highly conserved region of a known TRAF family molecule, PCR was performed with the aid of cDNA derived from various cell strains and tissues as a template. Thus, the base sequence of the gene of an unknown TRAF family molecule and the amino acid sequence of the TRAF family molecule encoded by the gene were elucidated. An antibody against the molecule was also prepared. By utilizing the TRAF family molecules, genes thereof, and antibodies against the molecules, there are provided methods for elucidating the functions of the proteins and methods for elucidating the signal transduction system of the TNF-R family involving the molecules, as well as probes for research and diagosis, which suggest applications in therapeutic agents.
    • 本发明涉及TRAF家族分子,编码该分子的多核苷酸,针对该分子的抗体以及该分子的反义多核苷酸。 使用能够扩增已知TRAF家族分子的最高度保守区域的寡DNA引物,借助于源自各种细胞株和组织的cDNA作为模板进行PCR。 因此,阐明了未知TRAF家族分子的基因的碱基序列和由该基因编码的TRAF家族分子的氨基酸序列。 还制备了抗分子的抗体。 通过利用TRAF家族分子,其基因和针对分子的抗体,提供了阐明蛋白质功能的方法和阐明涉及分子的TNF-R家族的信号转导系统的方法,以及用于 研究和诊断,这表明在治疗药物中的应用。