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    • 2. 发明授权
    • Conditioned seat
    • 条件座椅
    • US5921314A
    • 1999-07-13
    • US894316
    • 1997-10-07
    • Ferdinand SchullerHans-Georg RauhGunter LorenzenMichael Weiss
    • Ferdinand SchullerHans-Georg RauhGunter LorenzenMichael Weiss
    • B60N2/90A47C7/74A47C21/04B60N2/56B60H3/00F25D23/12
    • B60N2/5642B60N2/56B60N2/5628F16J15/3468Y10S454/907
    • The conditioned seat, has at least one seat contact surface (31), the outer side of which faces towards part of a passenger in the seat. An air-conditioning device (18) supplies conditioned air to the region of the inner side of the seat contact surface (31). An electrical heating element (24) is arranged in the region of the inner side of the seat contact surface (31) for warming the seat contact surface (31). A temperature sensor (28) detects the temperature in the region of the seat contact surface (31). For achieving a fast adjustment of the seat temperature to a preset desired temperature independent from the ambient temperature a controlling system (20) is provide which is in connection both with the air-conditioning device (18) and with the electrical heating element (24) and controls these corresponding to a pre-set desired temperature value in dependence on the temperature measured by the temperature sensor (28).
    • PCT No.PCT / EP96 / 00638 Sec。 371日期1997年10月7日第 102(e)日期1997年10月7日PCT提交1996年2月14日PCT公布。 WO96 / 25301 PCT出版物 日期1996年8月22日调节座椅具有至少一个座接触表面(31),其外侧面向座椅中乘客的一部分。 空调装置(18)将调节空气供给到座接触面(31)的内侧的区域。 电气加热元件(24)设置在座接触表面(31)的内侧的区域中,用于加热座接触表面(31)。 温度传感器(28)检测座接触面(31)的区域内的温度。 为了实现将座椅温度快速调节到独立于环境温度的预设期望温度,提供与空气调节装置(18)和电加热元件(24)连接的控制系统(20) 并且根据由温度传感器(28)测量的温度来对应于预设的所需温度值。
    • 4. 发明授权
    • Electric steering-wheel heating element
    • 电动方向盘加热元件
    • US5847360A
    • 1998-12-08
    • US760598
    • 1996-12-04
    • Gunter LorenzenMichael Weiss
    • Gunter LorenzenMichael Weiss
    • B62D1/06H05B3/20H05B3/58B60L1/02H05B3/50
    • H05B3/56B62D1/065H05B3/565
    • The electric steering-wheel heating element to be mounted on a steering wheel rim has a linear center region made of flat ribbon-shaped, electrically conductive material. A first side region and a second side region made of flat ribbon-shaped, electrically conductive material each have at least one curved side segment and. The shape of the center region and of the curved side segments is configured such that, after mounting, the center region covers an external circumferential region of the steering wheel rim, the first side region alongside a longitudinal side of the center region covers a side circumferential region on one side of the steering wheel rim and the second side region alongside the other longitudinal side of the center region covers a side circumferential region on the other side of the steering wheel rim.
    • 安装在方向盘边缘上的电动方向盘加热元件具有由扁平带状的导电材料制成的直线中心区域。 由扁平带状导电材料制成的第一侧面区域和第二侧面区域各自具有至少一个弯曲侧面区段, 中心区域和弯曲侧段的形状被构造成使得在安装之后,中心区域覆盖方向盘边缘的外周区域,沿着中心区域的纵向侧面的第一侧区域覆盖侧周边 方向盘边缘的一侧上的区域和沿着中心区域的另一纵向侧边的第二侧区域覆盖方向盘边缘的另一侧上的侧边区域。
    • 5. 发明申请
    • Optical Measuring System
    • 光学测量系统
    • US20130187067A1
    • 2013-07-25
    • US13812019
    • 2011-07-25
    • Michael WeissGuido Mertens
    • Michael WeissGuido Mertens
    • G01N21/59
    • G01N21/59A61L2/081G01N21/05G01N2021/0367
    • An optical measuring system includes at least one radiation source, at least one radiation receiver, and at least one flow through cell. The radiation emitted by the at least one radiation source passes at least partially in an optical path between the radiation source and the radiation receiver through the flow through cell and then strikes the at least one radiation receiver. The radiation receiver is embodied to output a signal dependent on the intensity of the radiation striking the radiation receiver, wherein the flow through cell is arranged in a cell holder, which is connected via a first connection interface releasably with the radiation receiver and which is connected via a second connection interface releasably with the radiation source.
    • 光学测量系统包括至少一个辐射源,至少一个辐射接收器和至少一个流通池。 由至少一个辐射源发射的辐射至少部分地在辐射源和辐射接收器之间的光路中穿过细胞通过,然后撞击至少一个辐射接收器。 辐射接收器被实现为输出取决于射入辐射接收器的辐射的强度的信号,其中流通池通过电池被布置在电池座中,电池座通过第一连接接口与放射线接收器可释放地连接并连接 经由可释放地与辐射源连接的第二连接接口。
    • 6. 发明申请
    • FIBRILLATION-RESISTANT INSULIN AND INSULIN ANALOGUES
    • 抗纤维蛋白胰岛素和胰岛素类似物
    • US20120316107A1
    • 2012-12-13
    • US13472833
    • 2012-05-16
    • Michael Weiss
    • Michael Weiss
    • C07K14/62A61K38/28C12N1/21C12N1/19C12N15/63C12N15/17A61P3/08
    • C07K14/62A61K38/00
    • A fibrillation-resistant insulin analogue may be a single-chain insulin analogue or a physiologically acceptable salt thereof, containing an insulin A chain sequence or an analogue thereof and an insulin B chain sequence or an analogue thereof connected by a polypeptide of 4-10 amino acids. The fibrillation-resistant insulin analogue preferably displays less than 1 percent fibrillation with incubation at 37° C. for at least 21 days. A single-chain insulin analogue displays greater in vitro insulin receptor binding than normal insulin while displaying less than or equal binding to IGFR than normal insulin. The fibrillation-resistant insulin may be used to treat a patient using an implantable or external insulin pump, due to its greater fibrillation resistance.
    • 抗纤维化胰岛素类似物可以是单链胰岛素类似物或其生理上可接受的盐,其含有胰岛素A链序列或其类似物,以及通过4-10个氨基的多肽连接的胰岛素B链序列或其类似物 酸。 抗纤维化胰岛素类似物优选在37℃下孵育至少21天显示低于1%的纤颤。 单链胰岛素类似物显示比正常胰岛素更大的体外胰岛素受体结合,而与正常胰岛素显示小于或等于IGFR的结合。 抗纤维化胰岛素可以用于使用可植入或外用的胰岛素泵治疗患者,因为它具有更大的抗起伏性。
    • 7. 发明申请
    • INSULIN ANALOGUES WITH CHLORINATED AMINO ACIDS
    • 具有氯化氨基酸的胰岛素类似物
    • US20120277148A1
    • 2012-11-01
    • US13515192
    • 2010-12-13
    • Michael Weiss
    • Michael Weiss
    • C07K14/62C12N15/63C12N1/21A61K38/28A61P3/10C12N15/17C12N1/19
    • C07K14/62A61K38/00
    • An insulin analogue comprises a B-chain polypeptide incorporating a chlorinated phenylalanine. The chlorinated phenylalanine may be located at position B24. The chlorinated phenylalanine may be para-monochloro-phenylalanine. The analogue may be of a mammalian insulin, such as human insulin. A nucleic acid encodes such an insulin analogue. The chlorinated insulin analogues retain significant activity. A method of treating a patient comprises administering a physiologically effective amount of the insulin analogue or a physiologically acceptable salt thereof to a patient. Chlorine substitution-based stabilization of insulin may reduce fibrillation and thereby enhance the treatment of diabetes mellitus in regions of the developing world lacking refrigeration.
    • 胰岛素类似物包含掺入氯化苯丙氨酸的B链多肽。 氯代苯丙氨酸可以位于B24位。 氯化苯丙氨酸可以是对 - 一氯 - 苯丙氨酸。 类似物可以是哺乳动物胰岛素,例如人胰岛素。 核酸编码这样的胰岛素类似物。 氯化胰岛素类似物保留显着的活性。 治疗患者的方法包括向患者施用生理有效量的胰岛素类似物或其生理上可接受的盐。 基于氯取代的胰岛素稳定可能减少原纤维化,从而增强发展中国家缺乏制冷的地区的糖尿病治疗。