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1. 发明授权

US06968235B2 Enhanced method and apparatus to identify and connect a small diameter lead with a low profile lead connector 失效
标题翻译：增强的方法和设备，用于识别和连接小直径导线与低剖面导线连接器
公开(公告)号：US06968235B2
公开(公告)日：2005-11-22
申请号：US10137158
申请日：2002-04-30
申请人： Elisabeth L. Belden , Eric V. Blaha , Eric H. Bonde , Ryan Cobian , Steven D. Goedeke , Gregory J. Haubrich , Douglas N. Hess , Nels D. Nerison , John L. Sommer , David L. Thompson , Jonathan C. Werder
发明人： Elisabeth L. Belden , Eric V. Blaha , Eric H. Bonde , Ryan Cobian , Steven D. Goedeke , Gregory J. Haubrich , Douglas N. Hess , Nels D. Nerison , John L. Sommer , David L. Thompson , Jonathan C. Werder
IPC分类号： A61N1/37 , A61B5/00 , A61N1/02 , A61N1/05 , A61N1/372 , A61N1/375 , A61N1/39 , A61N1/34
CPC分类号： A61N1/37252 , A61B5/0031 , A61B2560/0219 , A61N1/025 , A61N1/37223 , A61N1/3752 , A61N2001/0585
摘要： The present invention provides a practical, multi-polar, in-line connector system for use in connecting implantable medical devices (IMD) and associated non-standard, low profile medical electrical leads. In addition, the present invention provides a system that uses tool less, frictional, sealed, compressive electrical connections for most or all of the electrical interconnections between an IMD and a low profile lead. A protective sleeve seals the lead connector to the non-standard port to prevent intrusion of body fluids therein. In addition, optional microchip-based circuitry coupled to the sleeve enables wireless communication and remote programming for diverse IMDs. Memory associated with the circuitry can store, update and reprogram a wide variety of information relevant to the IMD, the patient, and the attending physician, among others. For example, the microchip may be used to identify the lead type and characteristics, as well as other useful data.
摘要翻译：本发明提供了一种用于连接可植入医疗装置（IMD）和相关联的非标准低剖面医疗电引线的实用的多极直插式连接器系统。另外，本发明提供了一种系统，该系统对于IMD和低剖面导线之间的大部分或全部电互连使用较少的，摩擦的，密封的，压缩的电连接。保护套将引线连接器密封到非标准端口，以防止其中的体液侵入。此外，耦合到套管的可选的基于微芯片的电路可实现针对不同IMD的无线通信和远程编程。与电路相关联的存储器可以存储，更新和重新编程与IMD，患者和主治医师等相关的各种各样的信息。例如，微芯片可用于识别引线类型和特性，以及其他有用的数据。

2. 发明授权

US07239916B2 Method and apparatus for automatic implantable medical lead recognition and configuration 有权
标题翻译：用于自动植入式医疗导线识别和配置的方法和装置
公开(公告)号：US07239916B2
公开(公告)日：2007-07-03
申请号：US10714123
申请日：2003-11-14
申请人： David L. Thompson , Steven D. Goedeke , Gregory J. Haubrich , Ryan Cobian , Eric Bonde , John L. Sommer , Jonathan Werder , Nels Nerison , Eric V. Blaha
发明人： David L. Thompson , Steven D. Goedeke , Gregory J. Haubrich , Ryan Cobian , Eric Bonde , John L. Sommer , Jonathan Werder , Nels Nerison , Eric V. Blaha
IPC分类号： A61N1/362
CPC分类号： A61N1/37252 , A61B5/0031 , A61B2560/0219 , A61N1/025 , A61N1/05 , A61N1/37223 , A61N1/3752 , A61N2001/0585
摘要： An automated identification and configuration system for use with an implantable medical device (IMD) is disclosed. The system includes a first communication circuit that is attached to, or otherwise carried by, a detachable component associated with the IMD such as a medical lead. The communication circuit stores data such as model numbers, serial numbers, technical data, and/or calibration information that describes the additional component. This information may be transferred by the first communications circuit to a second communications circuit that is external to the additional component. This transferred data can be used to automatically configure the internal circuitry and connection functions of the IMD to properly interface with, and support, the additional component. For example, the data can be used to automatically adjust amplifier gains or other sensor circuitry, or to configure a connector block to properly couple to the component. The data may further be entered into a patient record on an external programmer, or may be transferred to a central storage location to be generally accessible to health care providers. In one embodiment, the first communication circuit is a passive RF transponder. This first communication circuit may include a receiver as well as a transmitter to allow the circuit to programmably receive data at the time of component manufacture.
摘要翻译：公开了一种用于可植入医疗装置（IMD）的自动识别和配置系统。该系统包括第一通信电路，其连接到与IMD相关联的可拆卸部件（例如医疗引线）或由其携带。通信电路存储诸如型号，序列号，技术数据和/或描述附加组件的校准信息的数据。该信息可以由第一通信电路传送到附加组件外部的第二通信电路。该传输的数据可用于自动配置IMD的内部电路和连接功能，以正确地连接和支持附加组件。例如，数据可用于自动调整放大器增益或其他传感器电路，或配置连接器块以正确耦合到组件。数据可以进一步输入到外部编程器上的病人记录中，或者可以被传送到中央存储位置，以便卫生保健提供者通常可访问。在一个实施例中，第一通信电路是无源RF应答器。该第一通信电路可以包括接收器以及发射器，以允许电路在组件制造时可编程地接收数据。

3. 发明授权

US06675049B2 Method and apparatus for automatic implantable medical lead recognition and configuration 有权
公开(公告)号：US06675049B2
公开(公告)日：2004-01-06
申请号：US09907308
申请日：2001-07-17
申请人： David L. Thompson , Steven D. Goedeke , Gregory J. Haubrich , Ryan Cobian , Eric Bonde , John L. Sommer , Jonathan Werder , Nels Nerison , Eric V. Blaha
发明人： David L. Thompson , Steven D. Goedeke , Gregory J. Haubrich , Ryan Cobian , Eric Bonde , John L. Sommer , Jonathan Werder , Nels Nerison , Eric V. Blaha
IPC分类号： A61N136
CPC分类号： A61N1/37252 , A61B5/0031 , A61B2560/0219 , A61N1/025 , A61N1/05 , A61N1/37223 , A61N1/3752 , A61N2001/0585
摘要： An automated identification and configuration system for use with an implantable medical device (IMD) is disclosed. The system includes a first communication circuit that is attached to, or otherwise carried by, a detachable component associated with the IMD such as a medical lead. The communication circuit stores data such as model numbers, serial numbers, technical data, and/or calibration information that describes the additional component. This information may be transferred by the first communications circuit to a second communications circuit that is external to the additional component. This transferred data can be used to automatically configure the internal circuitry and connection functions of the IMD to properly interface with, and support, the additional component. For example, the data can be used to automatically adjust amplifier gains or other sensor circuitry, or to configure a connector block to properly couple to the component. The data may further be entered into a patient record on an external programmer, or may be transferred to a central storage location to be generally accessible to health care providers. In one embodiment, the first communication circuit is a passive RF transponder. This first communication circuit may include a receiver as well as a transmitter to allow the circuit to programmably receive data at the time of component manufacture.

4. 发明授权

US06539253B2 Implantable medical device incorporating integrated circuit notch filters 有权
公开(公告)号：US06539253B2
公开(公告)日：2003-03-25
申请号：US09729845
申请日：2000-12-05
申请人： David L. Thompson , Gregory J. Haubrich , Steven D. Goedeke
发明人： David L. Thompson , Gregory J. Haubrich , Steven D. Goedeke
IPC分类号： A61N116
CPC分类号： A61N1/08 , A61N1/025 , A61N1/37 , A61N1/37211 , A61N1/37229
摘要： Implantable medical devices (IMDs) having sense amplifiers for sensing physiologic signals and parameters, RF telemetry capabilities for uplink transmitting patient data and downlink receiving programming and interrogation commands to and from an external programmer or other medical device are disclosed. At least one IC chip and discrete components have a volume and dimensions that are optimally minimized to reduce its volumetric form factor. Miniaturization techniques include forming notch filters of MEMS structures or forming discrete circuit notch filters by one or more of: (1) IC fabricating inductors into one or more IC chips mounted to the RF module substrate; (2) mounting each IC chip into a well of the RF module substrate and using short bonding wires to electrically connect bond pads of the RF module substrate and the IC chip; and (3) surface mounting discrete capacitors over IC chips to reduce space taken up on the RF module substrate. The IC fabricated inductors are preferably fabricated as planar spiral wound conductive traces formed of high conductive metals to reduce trace height and width while maintaining low resistance, thereby reducing parasitic capacitances between adjacent trace side walls and with a ground plane of the IC chip. The spiral winding preferably is square or rectangular, but having truncated turns to eliminate 90° angles that cause point-to-point parasitic capacitances. The planar spiral wound conductive traces are further preferably suspended over the ground plane of the IC chip substrate by micromachining underlying substrate material away to thereby reduce parasitic capacitances.

5. 发明授权

US06535766B1 Implanted medical device telemetry using integrated microelectromechanical filtering 有权
标题翻译：使用集成微机电滤波的植入式医疗设备遥测
公开(公告)号：US06535766B1
公开(公告)日：2003-03-18
申请号：US09648604
申请日：2000-08-26
申请人： David L. Thompson , Gregory J. Haubrich , Steven D. Goedeke
发明人： David L. Thompson , Gregory J. Haubrich , Steven D. Goedeke
IPC分类号： A61N136
CPC分类号： A61N1/37229 , A61N1/025 , A61N1/08 , A61N1/37 , A61N1/37211
摘要： A telemetry receiver for an implantable medical device such as a cardiac pacemaker has an RF antenna coupled to a telemetry circuit that includes an out-of-band rejection filter comprising a microelectromechanical filter. The telemetry circuit further includes an amplifier coupled to the microelectromechanical filter and a demodulator coupled to the amplifier. The filter, amplifier and demodulator are all fabricated on a common integrated circuit die. A multichannel telemetry receiver for an implantable medical device has a plurality of microelectromechanical bandpass filters defining individual channels. A multiplexing circuit selects the signal of an individual bandpass filter channel for application to a demodulator circuit that recovers programming data from a modulated RF transmission from a programming unit. Identification of a preferred data transmission channel for communication of programming data to the implanted medical device is determined by obtaining samples of the signals being passed by each of a plurality of microelectromechanical bandpass filters that define individual channels and evaluating the samples to determine the noise level for each channel. The implantable medical device may be programmed to receive downlink telemetry communications from a programming unit on the channel identified as being the preferred data transmission channel having the lowest noise level.
摘要翻译：用于诸如心脏起搏器的可植入医疗装置的遥测接收器具有耦合到遥测电路的RF天线，该遥测电路包括包括微机电滤波器的带外抑制滤波器。遥测电路还包括耦合到微机电滤波器的放大器和耦合到放大器的解调器。滤波器，放大器和解调器全部在公共集成电路管芯上制造。用于可植入医疗装置的多通道遥测接收器具有限定各个通道的多个微机电带通滤波器。复用电路选择单个带通滤波器信道的信号，以应用于从编程单元从调制的RF传输中恢复编程数据的解调器电路。通过获得定义各个通道的多个微机电带通滤波器中的每一个通过的信号样本来确定用于将编程数据传送到植入的医疗装置的优选数据传输通道的识别，并评估样本以确定噪声水平每个频道。可植入医疗设备可以被编程为从识别为具有最低噪声电平的优选数据传输信道的信道上的编程单元接收下行链路遥测通信。

6. 发明授权

US5752976A World wide patient location and data telemetry system for implantable medical devices 失效
标题翻译：世界范围的可植入医疗器械的患者位置和数据遥测系统
公开(公告)号：US5752976A
公开(公告)日：1998-05-19
申请号：US494218
申请日：1995-06-23
申请人： Edwin G. Duffin , David L. Thompson , Steven D. Goedeke , Gregory J. Haubrich
发明人： Edwin G. Duffin , David L. Thompson , Steven D. Goedeke , Gregory J. Haubrich
IPC分类号： A61B5/00 , A61N1/37 , A61N1/372 , H04Q7/38 , H04Q9/00
CPC分类号： A61N1/37282 , G06F19/3418 , A61B5/1112
摘要： A system and method for communicating with a medical device implanted in an ambulatory patient and for locating the patient in order to selectively monitor device function, alter device operating parameters and modes and provide emergency assistance to and communications with a patient. The implanted device includes a telemetry transceiver for communicating data and operating instructions between the implanted device and an external patient communications control device that is either worn by or located in proximity to the patient within the implanted device transceiving range. The control device preferably includes a communication link with a remote medical support network, a global positioning satellite receiver for receiving positioning data identifying the global position of the control device, and a patient activated link for permitting patient initiated personal communication with the medical support network. A system controller in the control device controls data and voice communications for selectively transmitting patient initiated personal communications and global positioning data to the medical support network, for initiating telemetry out of data and operating commands from the implanted device and transmission of the same to the medical support network, and for receiving and initiating re-programming of the implanted device operating modes and parameters in response to instructions received from the medical support network. The communications link between the medical support network and the patient communications control device may comprise a world wide satellite network, hard-wired telephone network, a cellular telephone network or other personal communications system.
摘要翻译：一种用于与植入在步行病人中的医疗设备进行通信并用于定位患者的系统和方法，以便选择性地监测设备功能，改变设备操作参数和模式，并向患者提供紧急援助和与患者通信。植入装置包括遥测收发器，用于在植入的装置和外部患者通信控制装置之间传送数据和操作指令，所述外部患者通信控制装置在植入装置收发范围内由患者佩戴或位于患者附近。控制装置优选地包括与远程医疗支持网络的通信链路，用于接收标识控制装置的全局位置的定位数据的全球定位卫星接收机，以及用于允许患者发起与医疗支持网络的个人通信的患者激活的链路。控制装置中的系统控制器控制数据和语音通信，用于选择性地将患者发起的个人通信和全球定位数据发送到医疗支持网络，用于发起远程数据和从植入设备的操作命令并将其传输到医疗支持网络，以及响应于从医疗支持网络接收到的指令，接收和启动植入设备操作模式和参数的重新编程。医疗支持网络和患者通信控制设备之间的通信链路可以包括全球卫星网络，硬连线电话网络，蜂窝电话网络或其他个人通信系统。

7. 发明授权

US06292698B1 World wide patient location and data telemetry system for implantable medical devices 失效
标题翻译：世界范围的可植入医疗器械的患者位置和数据遥测系统
公开(公告)号：US06292698B1
公开(公告)日：2001-09-18
申请号：US09045275
申请日：1998-03-20
申请人： Edwin G. Duffin , David L. Thompson , Steven D. Goedeke , Gregory J. Haubrich
发明人： Edwin G. Duffin , David L. Thompson , Steven D. Goedeke , Gregory J. Haubrich
IPC分类号： A61N137
CPC分类号： A61N1/37282 , A61B5/1112 , G06F19/00 , G06F19/3418
摘要： A system for communicating with a medical device implanted in an ambulatory patient and for locating the patient in order to selectively monitor device function, alter device operating parameters and modes and provide emergency assistance to and communications with a patient. The implanted device includes a telemetry transceiver for communicating data and operating instructions between the implanted device and an external patient communications control device that is either worn by or located in proximity to the patient within the implanted device transceiving range. The control device preferably includes a communication link with a remote medical support network, a global positioning satellite receiver for receiving positioning data identifying the global position of the control device, and a patient activated link for permitting patient initiated personal communication with the medical support network. A system controller in the control device controls data and voice communications for selectively transmitting patient initiated personal communications and global positioning data to the medical support network, for initiating telemetry out of data and operating commands from the implanted device and transmission of the same to the medical support network, and for receiving and initiating re-programming of the implanted device operating modes and parameters in response to instructions received from the medical support network. The communications link between the medical support network and the patient communications control device may comprise a world wide satellite network, hard-wired telephone network, a cellular telephone network or other personal communications system.
摘要翻译：一种用于与植入在步行病人中的医疗设备进行通信并用于定位患者的系统，以便选择性地监测设备功能，改变设备操作参数和模式，并向患者提供紧急援助并与患者通信。植入装置包括遥测收发器，用于在植入的装置和外部患者通信控制装置之间传送数据和操作指令，所述外部患者通信控制装置在植入装置收发范围内由患者佩戴或位于患者附近。控制装置优选地包括与远程医疗支持网络的通信链路，用于接收标识控制装置的全局位置的定位数据的全球定位卫星接收机，以及用于允许患者发起与医疗支持网络的个人通信的患者激活的链路。控制装置中的系统控制器控制数据和语音通信，用于选择性地将患者发起的个人通信和全球定位数据发送到医疗支持网络，用于发起远程数据和从植入设备的操作命令并将其传输到医疗支持网络，以及响应于从医疗支持网络接收到的指令，接收和启动植入设备操作模式和参数的重新编程。医疗支持网络和患者通信控制设备之间的通信链路可以包括全球卫星网络，硬连线电话网络，蜂窝电话网络或其他个人通信系统。

8. 发明授权

US5843139A Adaptive, performance-optimizing communication system for communicating with an implanted medical device 失效
标题翻译：用于与植入式医疗设备通信的自适应性能优化通信系统
公开(公告)号：US5843139A
公开(公告)日：1998-12-01
申请号：US816223
申请日：1997-03-12
申请人： Steven D. Goedeke , Gregory J. Haubrich , John G. Keimel , David L. Thompson
发明人： Steven D. Goedeke , Gregory J. Haubrich , John G. Keimel , David L. Thompson
IPC分类号： A61N1/08 , A61N1/37 , A61N1/372 , G06T1/60 , H04B1/69 , H04L1/00 , H04L27/04
CPC分类号： A61N1/37252 , A61N1/37223 , A61N1/37247 , A61N1/3727 , Y10S128/903
摘要： An adaptive, performance-optimizing communication system for communicating with an implanted medical device in which signals are transmitted and received in accordance with predetermined, interrelated operational parameters, such as transmission rate, transmitter power, and the like. Various aspects of system performance, including bit error rate in received signals, the strength of received signals, the signal-to-noise ratio of received signals, the presence of local RF noise and non-telemetry related RF signals, and the like, are dynamically monitored by the communication system, to determine whether predetermined system performance goals are being met. If it is determined that one or more system performance goals are not being met, one or more operational parameters may be automatically adjusted so that desired performance can be achieved.
摘要翻译：一种用于与植入式医疗装置进行通信的自适应性能优化通信系统，其中根据预定的相互关联的操作参数（诸如传输速率，发射机功率等）来发射和接收信号。系统性能的各个方面，包括接收信号中的误码率，接收信号的强度，接收信号的信噪比，本地RF噪声和非遥测相关RF信号的存在等等。由通信系统动态监视，以确定是否满足预定的系统性能目标。如果确定没有满足一个或多个系统性能目标，则可以自动调整一个或多个操作参数，从而可以实现期望的性能。

9. 发明授权

US5683432A Adaptive, performance-optimizing communication system for communicating with an implanted medical device 失效
标题翻译：用于与植入式医疗设备通信的自适应性能优化通信系统
公开(公告)号：US5683432A
公开(公告)日：1997-11-04
申请号：US584851
申请日：1996-01-11
申请人： Steven D. Goedeke , Gregory J. Haubrich , John G. Keimel , David L. Thompson
发明人： Steven D. Goedeke , Gregory J. Haubrich , John G. Keimel , David L. Thompson
IPC分类号： A61N1/08 , A61N1/37 , A61N1/372 , G06T1/60 , H04B1/69 , H04L1/00 , H04L27/04
CPC分类号： A61N1/37252 , A61N1/37223 , A61N1/37247 , A61N1/3727 , Y10S128/903
摘要： An adaptive, performance-optimizing communication system for communicating with an implanted medical device in which signals are transmitted and received in accordance with predetermined, interrelated operational parameters, such as transmission rate, transmitter power, and the like. Various aspects of system performance, including bit error rate in received signals, the strength of received signals, the signal-to-noise ratio of received signals, the presence of local RF noise and non-telemetry related RF signals, and the like, are dynamically monitored by the communication system, to determine whether predetermined system performance goals are being met. If it is determined that one or more system performance goals are not being met, one or more operational parameters may be automatically adjusted so that desired performance can be achieved.
摘要翻译：一种用于与植入式医疗装置进行通信的自适应性能优化通信系统，其中根据预定的相互关联的操作参数（诸如传输速率，发射机功率等）来发射和接收信号。系统性能的各个方面，包括接收信号中的误码率，接收信号的强度，接收信号的信噪比，本地RF噪声和非遥测相关RF信号的存在等等。由通信系统动态监视，以确定是否满足预定的系统性能目标。如果确定没有满足一个或多个系统性能目标，则可以自动调整一个或多个操作参数，从而可以实现期望的性能。

10. 发明授权

US06169925A Telemetry system for implantable medical devices 有权
标题翻译：可植入医疗器械遥测系统
公开(公告)号：US06169925A
公开(公告)日：2001-01-02
申请号：US09302932
申请日：1999-04-30
申请人： Eduardo H. Villaseca , Garry L. Dublin , Steven D. Goedeke , Gregory J. Haubrich
发明人： Eduardo H. Villaseca , Garry L. Dublin , Steven D. Goedeke , Gregory J. Haubrich
IPC分类号： A61N1362
CPC分类号： A61N1/37229 , H01Q1/36 , H01Q9/16 , H01Q21/28 , Y10S128/903
摘要： A device for use in communication with an implantable medical device. The device is provided with a spatial diversity antenna array mounted to a housing and an RF transceiver operating at defined frequency, coupled to the antenna alray. The antenna array comprises two antennas spaced a fraction of the wavelength of the defined frequency from one another, each antenna including two antenna elements mounted to the housing and located oithogonal to one another. Selection of which of the antennas is employed is accomplished by an device controller, responsive to the quality of the signals received by the antennas.
摘要翻译：一种用于与可植入医疗装置通信的装置。该装置设置有安装到外壳的空间分集天线阵列和以限定的频率工作的RF收发器，耦合到天线分支。天线阵列包括两个天线，其彼此间隔定义频率的波长的一部分，每个天线包括安装到壳体并且彼此正交的两个天线元件。通过设备控制器来响应天线接收的信号的质量来实现选择哪个天线。

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