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1. 发明授权

US06968235B2 Enhanced method and apparatus to identify and connect a small diameter lead with a low profile lead connector 失效
标题翻译：增强的方法和设备，用于识别和连接小直径导线与低剖面导线连接器
公开(公告)号：US06968235B2
公开(公告)日：2005-11-22
申请号：US10137158
申请日：2002-04-30
申请人： Elisabeth L. Belden , Eric V. Blaha , Eric H. Bonde , Ryan Cobian , Steven D. Goedeke , Gregory J. Haubrich , Douglas N. Hess , Nels D. Nerison , John L. Sommer , David L. Thompson , Jonathan C. Werder
发明人： Elisabeth L. Belden , Eric V. Blaha , Eric H. Bonde , Ryan Cobian , Steven D. Goedeke , Gregory J. Haubrich , Douglas N. Hess , Nels D. Nerison , John L. Sommer , David L. Thompson , Jonathan C. Werder
IPC分类号： A61N1/37 , A61B5/00 , A61N1/02 , A61N1/05 , A61N1/372 , A61N1/375 , A61N1/39 , A61N1/34
CPC分类号： A61N1/37252 , A61B5/0031 , A61B2560/0219 , A61N1/025 , A61N1/37223 , A61N1/3752 , A61N2001/0585
摘要： The present invention provides a practical, multi-polar, in-line connector system for use in connecting implantable medical devices (IMD) and associated non-standard, low profile medical electrical leads. In addition, the present invention provides a system that uses tool less, frictional, sealed, compressive electrical connections for most or all of the electrical interconnections between an IMD and a low profile lead. A protective sleeve seals the lead connector to the non-standard port to prevent intrusion of body fluids therein. In addition, optional microchip-based circuitry coupled to the sleeve enables wireless communication and remote programming for diverse IMDs. Memory associated with the circuitry can store, update and reprogram a wide variety of information relevant to the IMD, the patient, and the attending physician, among others. For example, the microchip may be used to identify the lead type and characteristics, as well as other useful data.
摘要翻译：本发明提供了一种用于连接可植入医疗装置（IMD）和相关联的非标准低剖面医疗电引线的实用的多极直插式连接器系统。另外，本发明提供了一种系统，该系统对于IMD和低剖面导线之间的大部分或全部电互连使用较少的，摩擦的，密封的，压缩的电连接。保护套将引线连接器密封到非标准端口，以防止其中的体液侵入。此外，耦合到套管的可选的基于微芯片的电路可实现针对不同IMD的无线通信和远程编程。与电路相关联的存储器可以存储，更新和重新编程与IMD，患者和主治医师等相关的各种各样的信息。例如，微芯片可用于识别引线类型和特性，以及其他有用的数据。

2. 发明授权

US07184839B2 Catheter-delivered cardiac lead 有权
标题翻译：导管心脏导联
公开(公告)号：US07184839B2
公开(公告)日：2007-02-27
申请号：US10318518
申请日：2002-12-16
申请人： Willim J. Clemens , Michael L. Freiborg , Michael A. Ruff , Douglas N. Hess , Elisabeth L. Belden , Terrell M. Williams , Brian T. McHenry , Mark B. Bucheger , Timothy G. Laske , Matthew D. Bonner
发明人： Willim J. Clemens , Michael L. Freiborg , Michael A. Ruff , Douglas N. Hess , Elisabeth L. Belden , Terrell M. Williams , Brian T. McHenry , Mark B. Bucheger , Timothy G. Laske , Matthew D. Bonner
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N2001/058
摘要： A lead for delivering electrical signals to and/or receive electrical signals from a human heart that includes a solid inner conductor, and a fixation device having a titanium nitride coated surface and electrically coupled to the inner conductor. A steroid is applied to the titanium nitride surface of the fixation device, and at least one layer of insulation is positioned around the inner conductor. A conductive coil is positioned around and is insulated from the inner conductor, an electrode ring electrically coupled to the conductive coil is positioned around and is electrically isolated from the inner conductor, and an insulating spacer is positioned between and electrically isolates the ring electrode and the fixation device.
摘要翻译：用于将电信号传递到和/或接收来自包括实心内导体的人心脏的电信号的引线，以及具有氮化钛涂覆表面并电耦合到内导体的固定装置。将类固醇施加到固定装置的氮化钛表面，并且至少一层绝缘体围绕内部导体定位。导电线圈定位在内导体周围并与内导体绝缘，电耦合到导电线圈的电极环位于内导体周围并与内导体电隔离，并且绝缘间隔物位于电极之间并电隔离环电极和固定装置

3. 发明授权

US06901289B2 System for providing electrical stimulation to a left chamber of a heart 有权
标题翻译：用于向心脏的左室提供电刺激的系统
公开(公告)号：US06901289B2
公开(公告)日：2005-05-31
申请号：US10034905
申请日：2001-12-28
申请人： Roger Dahl , Thomas M. Soukup , Joe Perttu , Arnold Thornton , Elisabeth L. Belden , John L. Sommer
发明人： Roger Dahl , Thomas M. Soukup , Joe Perttu , Arnold Thornton , Elisabeth L. Belden , John L. Sommer
IPC分类号： A61N1/05 , A61N1/365
CPC分类号： A61N1/056 , A61N2001/0585
摘要： A medical electrical lead is disclosed that is adapted for placement in the coronary sinus, or a branch vein thereof. The lead includes a first and second pace/sense electrode. A selection mechanism is provided to select either the first or the second electrode for use as a cathode, with the other electrode being selected as the anode. According to another aspect of the invention, a high-voltage coil electrode may be provided between the first and second electrodes. The coil electrode may be electrically coupled to the anode to increase the shadow area of the coil electrode.
摘要翻译：公开了适于放置在冠状窦或其分支静脉中的医用电线。引线包括第一和第二步进/感测电极。提供选择机构来选择用作阴极的第一或第二电极，另一个电极被选择为阳极。根据本发明的另一方面，可以在第一和第二电极之间设置高压线圈电极。线圈电极可以电耦合到阳极以增加线圈电极的阴影面积。

4. 发明授权

US07292894B2 Methods and apparatus for joining small diameter conductors within medical electrical leads 有权
标题翻译：用于连接医用电线中的小直径导体的方法和装置
公开(公告)号：US07292894B2
公开(公告)日：2007-11-06
申请号：US10256490
申请日：2002-09-27
申请人： Elisabeth L. Belden
发明人： Elisabeth L. Belden
IPC分类号： A61N1/00 , H01R4/10
CPC分类号： A61N1/05 , H01R4/20 , H01R11/07 , H01R13/187 , H01R13/5837 , H01R31/06 , H01R2201/12
摘要： A conductor assembly and methods for mechanically and electrically coupling a small diameter conductor to a lead component having a relatively larger sized conductor bore is provided. The assembly includes a sizing member sized to fit securely around a relatively small diameter conductor and to further fit within a conductor bore so that temporary compression (e.g., crimping, crushing, or staking) of a discrete portion of the conductor bore mechanically couples, and establishes electrical communication between, the conductor and the lead component. Alternately, a conductive sleeve member having a relatively large diameter conductor bore is adapted to receive a sizing unit to downsize one side of the sleeve member in a manner similar to the foregoing. In this case, a relatively smaller diameter one of a pair of different diameter elongated conductors is firmly mechanically coupled and in electrical communication with a relatively larger diameter conductor.
摘要翻译：提供一种导体组件和用于将小直径导体机械地和电耦合到具有相对较大尺寸的导体孔的导线部件的导体组件和方法。组件包括尺寸适合紧固在相对较小直径的导体周围并且进一步配合在导体孔内的尺寸构件，使得导体孔的离散部分的临时压缩（例如压接，压碎或铆接）机械耦合，以及建立导体和导线组件之间的电气连通。或者，具有相对较大直径的导体孔的导电套筒构件适于接收尺寸单元以以类似于前述的方式缩小套筒构件的一侧。在这种情况下，一对不同直径的细长导体中的相对较小直径的一个被牢固地机械耦合并且与相对较大直径的导体电连通。

5. 发明授权

US07277762B2 Radiopague marking of lead electrode zone in a continuous conductor construction 失效
标题翻译：连续导体结构中铅电极区的不透射线标记
公开(公告)号：US07277762B2
公开(公告)日：2007-10-02
申请号：US10280276
申请日：2002-10-25
申请人： Elisabeth L. Belden , Gregory A. Boser , Michael R. Dollimer , Mary M. Morris
发明人： Elisabeth L. Belden , Gregory A. Boser , Michael R. Dollimer , Mary M. Morris
IPC分类号： A61N1/06
CPC分类号： A61N1/0563
摘要： A cardiac transvenous defibrillation lead has a continuous coil conductor within a layer of insulation. A portion of the coil conductor is exposed as a defibrillation electrode. In order to enhance fluoroscopic visualization of the exposed electrode during implant, the end of the exposed electrode is marked with a radiopaque element. The element may be in the form of an adhesive filled with radiopaque material that is used to backfill under the layer of insulation. Alternatively, a tube made of radiopaque material may be installed between the layer of insulation and the coil conductor.
摘要翻译：心脏静脉除颤引线在绝缘层内具有连续的线圈导体。线圈导体的一部分作为除颤电极露出。为了在植入期间增强暴露电极的荧光透视可视化，暴露电极的端部用不透射线的元件标记。元件可以是填充有不透射线材料的粘合剂的形式，其用于在绝缘层下方回填。或者，由不透射线材料制成的管可以安装在绝缘层和线圈导体之间。

6. 发明授权

US06501992B1 Radiopaque marking of lead electrode zone in a continuous conductor construction 失效
标题翻译：连续导体结构中铅电极区的不透射线标记
公开(公告)号：US06501992B1
公开(公告)日：2002-12-31
申请号：US09690163
申请日：2000-10-17
申请人： Elisabeth L. Belden , Gregory A. Boser , Michael R. Dollimer , Mary M. Morris
发明人： Elisabeth L. Belden , Gregory A. Boser , Michael R. Dollimer , Mary M. Morris
IPC分类号： A61N105
CPC分类号： A61N1/0563
摘要： A cardiac transvenous defibrillation lead has a continuous coil conductor within a layer of insulation. A portion of the coil conductor is exposed as a defibrillation electrode. In order to enhance fluoroscopic visualization of the exposed electrode during implant, the end of the exposed electrode is marked with a radiopaque element. The element may be in the form of an adhesive filled with radiopaque material that is used to backfill under the layer of insulation. Alternatively, a tube made of radiopaque material may be installed between the layer of insulation and the coil conductor.
摘要翻译：心脏静脉除颤引线在绝缘层内具有连续的线圈导体。线圈导体的一部分作为除颤电极露出。为了在植入期间增强暴露电极的荧光透视可视化，暴露电极的端部用不透射线的元件标记。元件可以是填充有不透射线材料的粘合剂的形式，其用于在绝缘层下方回填。或者，由不透射线材料制成的管可以安装在绝缘层和线圈导体之间。

7. 发明授权

US06847845B2 Connection system for a multi-polar lead 有权
标题翻译：多极引线连接系统
公开(公告)号：US06847845B2
公开(公告)日：2005-01-25
申请号：US10034143
申请日：2001-12-28
申请人： Elisabeth L. Belden
发明人： Elisabeth L. Belden
IPC分类号： A61N1/05 , A61N1/365
CPC分类号： A61N1/056
摘要： A connection system for electrically coupling selected conductors carried by a medical electrical lead to a source of energy such as an implantable pulse generator is disclosed. The connection system includes a first port that may be coupled to at least two conductors carried by a lead. The first port electrically couples the at least two conductors to each other, and to the source of energy. A second port is provided to respectively electrically couple at least one additional lead conductor to the source of energy.
摘要翻译：公开了一种用于将由医疗电引线携带的所选导体电耦合到诸如可植入脉冲发生器等能量源的连接系统。连接系统包括可以耦合到由引线承载的至少两个导体的第一端口。第一端口将至少两个导体彼此电耦合到能量源。提供第二端口以分别将至少一个附加引线导体电耦合到能量源。

8. 发明授权

US07925358B2 Radiopaque marking of lead electrode zone in a continuous conductor construction 失效
标题翻译：连续导体结构中铅电极区的不透射线标记
公开(公告)号：US07925358B2
公开(公告)日：2011-04-12
申请号：US11846774
申请日：2007-08-29
申请人： Elisabeth L. Belden , Mary M. Morris
发明人： Elisabeth L. Belden , Mary M. Morris
IPC分类号： A61N1/06
CPC分类号： A61N1/0563
摘要： A cardiac transvenous defibrillation lead has a continuous coil conductor within a layer of insulation. A portion of the coil conductor is exposed as a defibrillation electrode. In order to enhance fluoroscopic visualization of the exposed electrode during implant, the end of the exposed electrode is marked with a radiopaque element. The element may be in the form of an adhesive filled with radiopaque material that is used to backfill under the layer of insulation. Alternatively, a tube made of radiopaque material may be installed between the layer of insulation and the coil conductor.
摘要翻译：心脏静脉除颤引线在绝缘层内具有连续的线圈导体。线圈导体的一部分作为除颤电极露出。为了在植入期间增强暴露电极的荧光透视可视化，暴露电极的端部用不透射线的元件标记。元件可以是填充有不透射线材料的粘合剂的形式，其用于在绝缘层下方回填。或者，由不透射线材料制成的管可以安装在绝缘层和线圈导体之间。

9. 发明授权

US5957968A Suture sleeve with lead locking device 失效
标题翻译：带导线锁定装置的缝合套管
公开(公告)号：US5957968A
公开(公告)日：1999-09-28
申请号：US938216
申请日：1997-09-26
申请人： Elisabeth L. Belden , Dale A. Wahlstrom , Mark Marshall , Scott E. Jahns
发明人： Elisabeth L. Belden , Dale A. Wahlstrom , Mark Marshall , Scott E. Jahns
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/0582
摘要： An anchoring sleeve for retaining an electrical lead including a sleeve base and a locking member latchable to the sleeve base to lock the locking member to the sleeve base encircling the lead and engaging it around its full circumference. The locking member may be an arcuate member joined to said sleeve base by a hinge and pivotable to latch said locking member to the sleeve base. Alternatively the locking member may be a member formed separately from the sleeve base. The base may be provided with one or more C-shaped members to temporarily retain the lead prior to latching.
摘要翻译：一种用于保持电引线的固定套筒，其包括套筒基座和可锁定到套筒底座上的锁定构件，以将锁定构件锁定到环绕引线的套筒底座上并将其接合在其整个圆周周围。锁定构件可以是通过铰链连接到所述套筒底座的弓形构件，并且可枢转以将所述锁定构件锁定到套筒基座。或者，锁定构件可以是与套筒基部分开形成的构件。基座可以设置有一个或多个C形构件，以在闩锁之前临时保持引线。

10. 发明授权

US5409455A Vascular navigation and visualization assist device 失效
标题翻译：血管导航和可视化辅助装置
公开(公告)号：US5409455A
公开(公告)日：1995-04-25
申请号：US89003
申请日：1993-07-09
申请人： Elisabeth L. Belden
发明人： Elisabeth L. Belden
IPC分类号： A61M25/06 , A61M3/00
CPC分类号： A61M25/09041 , A61M25/0662 , Y10S604/902
摘要： An intravascular device to assist in the visualization of intravascular lumens and the navigation of guide members, the device including two elongate coaxial tubes which define a central lumen and an annular lumen. A manifold is coupled to the proximal end of the two tubes and includes a first port connected to the central lumen and a second port in fluid communication with the annular lumen. The central lumen and the annular lumen are fluidly independent at the proximal end and are open to the vasculature at the distal end. The coaxial tubes engage each other at the distal end to limit longitudinal movement therebetween.
摘要翻译：一种血管内装置，用于辅助可视化的血管内腔和引导构件的导航，该装置包括限定中心腔和环形腔的两个细长同轴管。歧管联接到两个管的近端，并且包括连接到中心腔的第一端口和与环形腔流体连通的第二端口。中央管腔和环形腔在近端处是流体独立的，并且在远端处对脉管系统开放。同轴管在远端处彼此接合以限制它们之间的纵向移动。

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