会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 7. 发明授权
    • 5-membered ring compounds
    • 5元环化合物
    • US06380262B1
    • 2002-04-30
    • US09762265
    • 2001-02-06
    • Eiji KobayashiHiromu OhnogiNobuto KoyamaKatsushige IkaiHiroaki SagawaIkunoshin Kato
    • Eiji KobayashiHiromu OhnogiNobuto KoyamaKatsushige IkaiHiroaki SagawaIkunoshin Kato
    • A61K3112
    • C07K5/0215A61K38/00
    • 5-Membered ring compounds represented by general formula (I), optically active isomers thereof or salts of the same. These compounds have physiological activities including a carcinostatic effect. In said formula the bond shown by the dotted line in the 5-membered ring represents that this 5-membered ring may be either a cyclopentene ring having a double bond or a saturated cyclopentane ring, and when the 5-membered ring is a cyclopentene ring, X is OR1, Y is ═O and Z is H, and when it is a cyclopentane ring, X is ═O, Y is OR2 and Z is OR3, (wherein R1 is R4 or —(CO)—R5; R2 is H, —R6 or —(CO)—R7; and R3 is H, R8 or (CO)—R9 (wherein R4, R5, R6, R7, R8 and R9 are the same or different and each represents an aliphatic, aromatic or aliphatic aromatic group, and R5, R7 and R9 may be each H), provided that the case where R2═R3═H is excluded); and W represents a residue obtained by eliminating SH from an SH-containing compound.
    • 由通式(I)表示的5-元环化合物,其旋光异构体或其盐。 这些化合物具有包括致癌作用的生理活性。 在所述式中,五元环中虚线所示的键表示该5元环可以是具有双键或饱和环戊烷环的环戊烯环,当5元环为环戊烯环时 X为OR 1,Y为= O且Z为H,当为环戊烷环时,X为= O,Y为OR 2,Z为OR 3,(其中R1为R4或 - (CO)-R5; R2为 H,-R6或 - (CO)-R7; R3为H,R8或(CO)-R9(其中R4,R5,R6,R7,R8和R9相同或不同,各自表示脂族,芳族或 脂族芳族基团,R 5,R 7和R 9可以各自为H),条件是排除R2 = R3 = H的情况); W表示通过从含SH化合物中除去SH而得到的残基。