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1. 发明申请

WO2013143609A1 DEVICES AND METHODS FOR THE TREATMENT OF METABOLIC DISORDERS 审中-公开
标题翻译：用于治疗代谢性疾病的装置和方法
公开(公告)号：WO2013143609A1
公开(公告)日：2013-10-03
申请号：PCT/EP2012/055834
申请日：2012-03-30
申请人： ETHICON ENDO-SURGERY, INC. , FELDER, Kevin D. , LONG, Gary L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S.
发明人： FELDER, Kevin D. , LONG, Gary L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S.
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/0509 , A61N1/36007
摘要： A system for stimulating the release of satiety hormone in a subject comprises a stimulus device (1 1 ) having an electrical pulse generator (2) and multiple stimulus electrodes (3) adapted to apply electrical stimuli to a tissue of a gastrointestinal system of the subject, the stimulus electrodes (3) being arranged at a distance to one another in multiple positions and the stimulus device (1 ) being configured to time-dependently switch selected ones of the stimulus electrodes (3) from an energized state to a non-energized state and vice versa for time-dependently changing the location of application of the stimulus.
摘要翻译：用于刺激受试者中饱腹感激素释放的系统包括具有电脉冲发生器（2）的刺激装置（11）和适于对受试者的胃肠系统的组织施加电刺激的多个刺激电极（3）刺激电极（3）在多个位置彼此间隔一定距离地布置，并且刺激装置（1）构造成将刺激电极（3）中的所选择的激励电极从激励状态时间依赖地切换到非通电状态，反之亦然，从而随时改变刺激应用的位置。

2. 发明申请

WO2013143603A1 DEVICES AND METHODS FOR THE TREATMENT OF METABOLIC DISORDERS 审中-公开
标题翻译：用于治疗代谢性疾病的装置和方法
公开(公告)号：WO2013143603A1
公开(公告)日：2013-10-03
申请号：PCT/EP2012/055813
申请日：2012-03-30
申请人： ETHICON ENDO-SURGERY, INC. , FELDER, Kevin D. , LONG, Gary L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S.
发明人： FELDER, Kevin D. , LONG, Gary L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S.
IPC分类号： A61N1/05 , A61N1/04 , A61N1/36
CPC分类号： A61N1/0509 , A61N1/0408 , A61N1/0476 , A61N1/36007
摘要： A system for stimulating the release of satiety hormone in a subject includes a stimulus device (1) having an electrical pulse generator (2) and stimulus electrodes (3) adapted to apply an electrical stimulus to a tissue, the stimulus device (1) being adapted to be endoluminally introduced in a gastrointestinal system of the subject, and means (9, 16, 17, 42) for anchoring the stimulus device permanently in a target location inside the gastrointestinal system in a position in which the stimulus electrodes engage a tissue of said gastrointestinal system.
摘要翻译：用于刺激受试者中饱腹感激素释放的系统包括具有电脉冲发生器（2）的刺激装置（1）和适于对组织施加电刺激的刺激电极（3），刺激装置（1）为适于在受试者的胃肠系统中被内窥镜引入，以及用于将刺激装置永久地固定在胃肠系统内的目标位置中的装置（9,16,17,42），其中刺激电极接合刺激电极的组织说胃肠系统。

3. 发明申请

WO2013087096A1 ENDOLUMINAL SLEEVE DEVICE AND METHODS FOR DEPLOYING AN ENDOLUMINAL SLEEVE IN THE GI TRACT 审中-公开
标题翻译：内镜套管装置及其在胃肠道内部分泌泌尿管的方法
公开(公告)号：WO2013087096A1
公开(公告)日：2013-06-20
申请号：PCT/EP2011/072637
申请日：2011-12-13
申请人： ETHICON ENDO-SURGERY, INC. , ZEINER, Mark, Steven , ORTIZ, Mark, Steven , BERGER, José, M. , SEELEY, Randy, J. , VOEGELE, James, W. , MURRAY, Michael, A. , D'ARCANGELO, Michele , HARRIS, Jason , PASTORELLI, Alessandro , BENZINGER, Carrie , CAGLE, David
发明人： ZEINER, Mark, Steven , ORTIZ, Mark, Steven , BERGER, José, M. , SEELEY, Randy, J. , VOEGELE, James, W. , MURRAY, Michael, A. , D'ARCANGELO, Michele , HARRIS, Jason , PASTORELLI, Alessandro , BENZINGER, Carrie , CAGLE, David
IPC分类号： A61F2/04
CPC分类号： A61F2/04 , A61F5/0076 , A61F2002/045
摘要： An endoluminal sleeve device (1) for internally lining a section of the Gl tract comprises a sleeve (2) having a longitudinal extension and a transverse extension defining a cross section of the sleeve (2), compacting means attached to the sleeve (2) and constraining a sleeve wall (8) in a transversally folded shape which narrows the cross section of the wall (8) along a prevalent portion of the longitudinal extension during longitudinally deploying the wall (8) to its full longitudinal extension, wherein the compacting means can be released when the wall (8) is longitudinally unfolded, thereby allowing the wall (8) to transversally unfold from said narrowed cross-section to an expanded cross section.
摘要翻译：用于在内部衬里Gl道的一部分的腔内套筒装置（1）包括具有纵向延伸的套筒（2）和限定套筒（2）的横截面的横向延伸部，附接到套筒（2）的压实装置并且以横向折叠的形式约束套管壁（8），其沿纵向展开所述壁（8）至其全部纵向延伸部，沿着所述纵向延伸部的普通部分使所述壁（8）的横截面变窄，其中所述压实装置当壁（8）纵向展开时可以释放，从而允许壁（8）从所述变窄的横截面横向展开至扩展的横截面。

4. 发明申请

WO2012107079A1 AN ENDOLUMINAL LINING SYSTEM 审中-公开
标题翻译：内膜内衬系统
公开(公告)号：WO2012107079A1
公开(公告)日：2012-08-16
申请号：PCT/EP2011/051814
申请日：2011-02-08
申请人： ETHICON ENDO-SURGERY, INC. , PASTORELLI, Alessandro , HARRIS, Jason , ORTIZ, Mark Steven , D'ARCANGELO, Michele
发明人： PASTORELLI, Alessandro , HARRIS, Jason , ORTIZ, Mark Steven , D'ARCANGELO, Michele
IPC分类号： A61F5/00
CPC分类号： A61F5/0076 , A61F5/0089
摘要： An endoluminal lining system for internally lining a section of the gastrointestinal tract comprises a flexible tubular lining (2) and an anchoring device (5) connected to the lining (2). The anchoring device (5) comprises a distal compression ring (6) and a proximal compression ring (7) initially separate from the distal compression ring (6), the distal and proximal compression rings (6, 7) forming a central passage opening (11), co-operating opposite tissue clamping surfaces (8, 9) and locking means (13; 22) adapted to lock the distal compression ring (6) to the proximal compression ring (7) in a tissue clamping configuration.
摘要翻译：用于内部衬垫胃肠道部分的腔内衬系统包括柔性管状衬垫（2）和连接到衬垫（2）的锚定装置（5）。锚定装置（5）包括远端压缩环（6）和最初与远侧压缩环（6）分离的近端压缩环（7），远侧和近端压缩环（6,7）形成中心通道开口组合夹紧表面（8,9）和合适的相对组织夹持表面（8,9）和锁定装置（13; 22），其适于以组织夹持构型将远端压缩环（6）锁定到近端压缩环（7）。

5. 发明申请

WO2012007046A1 A SYSTEM REGULATING THE DISPENSING OF A BODY FLUID 审中-公开
标题翻译：调节体液分配的系统
公开(公告)号：WO2012007046A1
公开(公告)日：2012-01-19
申请号：PCT/EP2010/060273
申请日：2010-07-16
申请人： ETHICON ENDO-SURGERY, INC. , FRIED, Martin , BILOTTI, Federico , GALVAO NETO, Manoel , ORTIZ, Mark Steven , PASTORELLI, Alessandro , ALBRECHT, Thomas Edward , HESS, Christopher, J. , STOKES, Michael, J. , ZEINER, Mark, S.
发明人： FRIED, Martin , BILOTTI, Federico , GALVAO NETO, Manoel , ORTIZ, Mark Steven , PASTORELLI, Alessandro , ALBRECHT, Thomas Edward , HESS, Christopher, J. , STOKES, Michael, J. , ZEINER, Mark, S.
IPC分类号： A61F5/00
CPC分类号： A61F5/0076
摘要： A system (11) for regulating the dispensing of body fluid comprises a regulating valve (12) adapted to be placed in the flow path of a body fluid and a physiological characteristic- sensing device (13) in signal communication with the regulating valve (12) and configured to generate a control signal (14) in dependency from the physiological characteristic, wherein the regulating valve (12) is adapted to change a rate of flow of the body fluid in response to the control signal (14).
摘要翻译：用于调节体液分配的系统（11）包括适于放置在体液的流动路径中的调节阀（12）和与调节阀（12）信号连通的生理特征检测装置（13）），并且被配置为根据生理特征产生控制信号（14），其中调节阀（12）适于响应于控制信号（14）改变体液的流速。

6. 发明申请

WO2011149879A2 INTESTINAL BRAKE INDUCING INTRALUMINAL THERAPEUTIC SUBSTANCE ELUTING DEVICES AND METHODS 审中-公开
标题翻译： INTESTINAL BRAKE INDING IN INTRALUMINAL THERAPEUTIC THEAPEUTIC TYSTURE ELDTING ELTERTING DEVICES AND METHODS
公开(公告)号：WO2011149879A2
公开(公告)日：2011-12-01
申请号：PCT/US2011/037660
申请日：2011-05-24
申请人： ETHICON ENDO-SURGERY, INC. , ALBRECHT, Thomas, E. , ALDRIDGE, Jeffrey, L. , BAKOS, Gregory, J. , CROPPER, Michael, S. , HERRERA-DAVIS, Denzel, Z. , DLUGOS, Daniel, F. , HARRIS, Jason, L. , HESS, Christopher, J. , HUNT, John, V. , MALAVIYA, Prasanna , ORTIZ, Mark, S. , OVERMYER, Mark, D. , PASTORELLI, Alessandro , ROBERTSON, Galen, C. , SHELTON, Frederick, E. , STOKES, Michael, J. , THOMPSON, Suzanne , TIMM, Richard, W. , VOEGELE, James, W. , WEISENBURGH, William B., III , WIDENHOUSE, Christopher W. , WIDENHOUSE, Tamara S. Vetro , WOODARD, James A., Jr. , XATES, David C. , ZEINER, Mark S. , ZWOLINSKY, Andrew M.
发明人： ALBRECHT, Thomas, E. , ALDRIDGE, Jeffrey, L. , BAKOS, Gregory, J. , CROPPER, Michael, S. , HERRERA-DAVIS, Denzel, Z. , DLUGOS, Daniel, F. , HARRIS, Jason, L. , HESS, Christopher, J. , HUNT, John, V. , MALAVIYA, Prasanna , ORTIZ, Mark, S. , OVERMYER, Mark, D. , PASTORELLI, Alessandro , ROBERTSON, Galen, C. , SHELTON, Frederick, E. , STOKES, Michael, J. , THOMPSON, Suzanne , TIMM, Richard, W. , VOEGELE, James, W. , WEISENBURGH, William B., III , WIDENHOUSE, Christopher W. , WIDENHOUSE, Tamara S. Vetro , WOODARD, James A., Jr. , XATES, David C. , ZEINER, Mark S. , ZWOLINSKY, Andrew M.
IPC分类号： A61M5/00
CPC分类号： A61F5/0079 , A61K9/0065 , A61M5/14276 , A61M31/002 , A61M39/0208 , A61M2210/106 , A61M2210/1064
摘要： Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices may be accomplished via stabilized implantable systems and ingestible pills. In one aspect, a method of inducing satiety includes implanting an implant within a lumen of a gastrointestinal tract and retaining a portion of chyme that flows by the implant within a body of the implant. The method further involves re-releasing the retained chyme from the implant into the gastrointestinal tract at a predetermined rate slower than a rate caused by natural peristalsis.
摘要翻译：方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。这些方法和装置可以通过稳定的可植入系统和可摄取的药丸来实现。一方面，一种诱导饱腹感的方法包括将植入物植入胃肠道的内腔中，并且将植入物流动的部分保持在植入物的体内。该方法还包括以比由天然蠕动引起的速率慢的预定速率将留置的食糜从植入物再释放到胃肠道中。

7. 发明申请

WO2011059671A2 A METHOD OF TREATING METABOLIC DISORDER BY SEVERING THE BILE DUCT 审中-公开
标题翻译：一种通过切割双管道治疗代谢障碍的方法
公开(公告)号：WO2011059671A2
公开(公告)日：2011-05-19
申请号：PCT/US2010/053772
申请日：2010-10-22
申请人： ETHICON ENDO-SURGERY, INC. , ORTIZ, Mark, S. , MESSERLY, Jeffrey, D. , ELMER, Lucas, B. , OVERMYER, Mark, D. , PASTORELLI, Alessandro , SHELTON, Frederick, E. , ROBERTSON, Galen, C. , BALEK, Stephen, J.
发明人： ORTIZ, Mark, S. , MESSERLY, Jeffrey, D. , ELMER, Lucas, B. , OVERMYER, Mark, D. , PASTORELLI, Alessandro , SHELTON, Frederick, E. , ROBERTSON, Galen, C. , BALEK, Stephen, J.
IPC分类号： A61B17/11 , A61F5/00
CPC分类号： A61F5/0013 , A61M27/002 , A61M2210/1057

8. 发明申请

WO2008135082A1 A COUPLING DEVICE FOR PERFORMING ENDOLUMINAL AND/OR TRANSLUMINAL SURGERY 审中-公开
标题翻译：用于执行内膜和/或斜面手术的联合装置
公开(公告)号：WO2008135082A1
公开(公告)日：2008-11-13
申请号：PCT/EP2007/054317
申请日：2007-05-03
申请人： Ethicon Endo-Surgery, Inc. , PASTORELLI, Alessandro , TACCHINO, Roberto
发明人： PASTORELLI, Alessandro , TACCHINO, Roberto
IPC分类号： A61B17/11 , A61B17/00
CPC分类号： A61B17/1114 , A61B2017/00477 , A61B2017/00557
摘要： A coupling device (1) for coupling a first surgical device to a second surgical device comprises a coupling portion (2) connectable to the first surgical device and comprising an inflatable anchoring head (4), a catching portion (3) connectable to the second surgical device and defining a receiving space (9) for receiving at least part of the anchoring head (4) and an access aperture (10) through which the anchoring head (4) is insertable into the receiving space (9), an activating device (6) connected to the anchoring head (4) and configured to deform the anchoring head (4) such that it can take on an expanded configuration and a retracted configuration. The access aperture (10) is configured to allow insertion and withdrawal of the anchoring head (4) when it is retracted and to lock the at least partially inserted anchoring head (4) to the catching portion (3) when it is expanded.
摘要翻译：用于将第一手术装置耦合到第二手术装置的联接装置（1）包括可连接到第一手术装置的联接部分（2），并且包括可充气锚固头部（4），可连接到第二手术装置的第二手术装置手术装置并且限定用于容纳锚固头部（4）的至少一部分的接纳空间（9）和固定头部（4）可插入到容纳空间（9）中的进入孔（10），启动装置（6），其连接到所述锚固头（4）并且构造成使所述锚固头（4）变形，使得其可以承受膨胀构型和缩回构型。进入孔（10）被构造成允许锚定头（4）在其缩回时插入和退出，并且当扩张时将至少部分插入的锚固头（4）锁定到捕获部分（3）。

9. 发明申请

WO2007104397A1 DEVICE FOR THE MANIPULATION OF BODY TISSUE 审中-公开
标题翻译：用于操作身体组织的装置
公开(公告)号：WO2007104397A1
公开(公告)日：2007-09-20
申请号：PCT/EP2007/001168
申请日：2007-02-12
申请人： ETHICON ENDO-SURGERY, INC. , TACCHINO, Roberto , D'ARCANGELO, Michele , PASTORELLI, Alessandro , KUHNS, Jesse, J. , BILOTTI, Federico
发明人： TACCHINO, Roberto , D'ARCANGELO, Michele , PASTORELLI, Alessandro , KUHNS, Jesse, J. , BILOTTI, Federico
IPC分类号： A61B1/018 , A61B17/29
CPC分类号： A61B17/29 , A61B1/0014 , A61B1/018 , A61B90/50 , A61B2017/00278 , A61B2017/3447
摘要： A device (1) for manipulating body tissue comprises a base structure (2, 102) and at least one tubular member (3) having a proximal end (4) and an orientable distal end (5) that defines a seat (6) for supporting a surgical instrument (7), in which the tubular member is connected to the base structure. An actuation mechanism (8) is suitable for orientating the distal end of the tubular member to take it into certain operative configurations. The actuation mechanism is also connected to the base structure. Means (23, 24) are also foreseen for the connection of the base structure to a distal end portion (9) of an insertion tube (10) of an endoscope or laparoscope, so that the actuation mechanism and the tubular member are arranged outside the insertion tube. The tubular member interacts with the actuation mechanism so that a movement of an actuation portion of the tubular member with respect to the base structure leads to the orientation of the orientable end.
摘要翻译：用于操纵身体组织的装置（1）包括基部结构（2,102）和至少一个具有近端（4）和可定向远端（5）的管状构件（3），所述远端用于限定座（6）支撑外科器械（7），其中管状构件连接到基部结构。致动机构（8）适于定向管状构件的远端以将其带入某些操作构型。致动机构也连接到基座结构。还预见了用于将基部结构连接到内窥镜或腹腔镜的插入管（10）的远端部分（9）的装置（23,24），使得致动机构和管状构件布置在插管。管状构件与致动机构相互作用，使得管状构件的致动部分相对于基部结构的运动导致可取向端的取向。

10. 发明申请

WO2007093198A1 A DEVICE, CLIP, ENDOSCOPE AND METHOD FOR THE INTRALUMINAL TREATMENT OF TISSUE, E.G. HEMORRHOIDS 审中-公开
标题翻译：用于组织内皮治疗的装置，夹子，内窥镜和方法，E.G. 痔疮
公开(公告)号：WO2007093198A1
公开(公告)日：2007-08-23
申请号：PCT/EP2006/007355
申请日：2006-07-26
申请人： ETHICON ENDO-SURGERY, INC. , THOMPSON, Brian, James , POPOVIC, Drago , PASTORELLI, Alessandro , BILOTTI, Federico
发明人： THOMPSON, Brian, James , POPOVIC, Drago , PASTORELLI, Alessandro , BILOTTI, Federico
IPC分类号： A61B17/064 , A61B17/072 , A61B17/068 , A61B17/128 , A61B17/122 , A61B1/31
CPC分类号： A61B17/072 , A61B1/31 , A61B17/0643 , A61B17/068 , A61B17/07207 , A61B17/1227 , A61B17/1285 , A61B2017/0641 , A61B2017/07221 , A61B2017/3452
摘要： A device for the intraluminal treatment of tissue comprises a handle, a shaft which extends from the handle and a head arranged at the distal end of the shaft, wherein the head comprises at least one jaw, movable between an open position, wherein it defines a window for the insertion of the tissue and surrounding tissue, and a closed position, and wherein the shaft extends between the handle and head in a curvilinear longitudinal direction.
摘要翻译：用于腔内处理组织的装置包括手柄，从手柄延伸的轴和布置在轴的远端的头部，其中头部包括至少一个可在打开位置之间移动的钳口，其中，窗口，用于插入组织和周围组织，以及关闭位置，并且其中轴在曲线纵向方向上在手柄和头部之间延伸。

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