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1. 发明申请

WO2013143600A1 DEVICES AND METHODS FOR THE TREATMENT OF METABOLIC DISORDERS. 审中-公开
标题翻译：用于治疗代谢性疾病的装置和方法。
公开(公告)号：WO2013143600A1
公开(公告)日：2013-10-03
申请号：PCT/EP2012/055798
申请日：2012-03-30
申请人： ETHICON ENDO-SURGERY, INC. , FELDER, Kevin, D. , LONG, Gary, L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik, S.
发明人： FELDER, Kevin, D. , LONG, Gary, L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik, S.
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/36067 , A61N1/0509
摘要： A system for stimulating the release of satiety hormone in a subject, the system comprising a stimulus device (11) having an electrical pulse generator (2) and multiple stimulus electrodes (3) adapted to apply electrical stimuli to a tissue of a gastrointestinal system of the subject, one or more time-dependently bioabsorbable or biofragmentable isolating layers (30) which cover at least one of the stimulus electrodes (3) such that the initially covered stimulus electrode (3) is exposed only after erosion of said one or more isolating layers (30).
摘要翻译：一种用于刺激受试者中饱腹感激素释放的系统，所述系统包括具有电脉冲发生器（2）和多个刺激电极（3）的刺激装置（11）和适于将电刺激施加到胃肠系统组织受试者，覆盖至少一个刺激电极（3）的一个或多个时间依赖性生物可吸收或生物可分散的隔离层（30），使得最初被覆盖的刺激电极（3）仅在所述一个或多个隔离层层（30）。

2. 发明申请

WO2013143599A1 DEVICES AND METHODS FOR THE TREATMENT OF METABOLIC DISORDERS. 审中-公开
标题翻译：用于治疗代谢性疾病的装置和方法。
公开(公告)号：WO2013143599A1
公开(公告)日：2013-10-03
申请号：PCT/EP2012/055795
申请日：2012-03-30
申请人： ETHICON ENDO-SURGERY, INC. , FELDER, Kevin D. , LONG, Gary L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S.
发明人： FELDER, Kevin D. , LONG, Gary L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S.
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/36067 , A61N1/0509
摘要： A system for stimulating the release of satiety hormone in a subject comprises a stimulus device (1) having an electrical pulse generator (2) and stimulus electrodes (3) adapted to apply an electrical stimulus to a tissue, the stimulus device (1) being configured to time dependently move at least one of the stimulus electrodes (3) for time-dependently changing the location of application of the stimulus.
摘要翻译：用于刺激受试者中饱腹感激素释放的系统包括具有电脉冲发生器（2）和刺激电极（3）的刺激装置（1），刺激电极（3）适于对组织施加电刺激，刺激装置（1）被配置为时间依赖地移动至少一个所述刺激电极（3）以随时改变所述刺激的施加位置。

3. 发明申请

WO2013143609A1 DEVICES AND METHODS FOR THE TREATMENT OF METABOLIC DISORDERS 审中-公开
标题翻译：用于治疗代谢性疾病的装置和方法
公开(公告)号：WO2013143609A1
公开(公告)日：2013-10-03
申请号：PCT/EP2012/055834
申请日：2012-03-30
申请人： ETHICON ENDO-SURGERY, INC. , FELDER, Kevin D. , LONG, Gary L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S.
发明人： FELDER, Kevin D. , LONG, Gary L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S.
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/0509 , A61N1/36007
摘要： A system for stimulating the release of satiety hormone in a subject comprises a stimulus device (1 1 ) having an electrical pulse generator (2) and multiple stimulus electrodes (3) adapted to apply electrical stimuli to a tissue of a gastrointestinal system of the subject, the stimulus electrodes (3) being arranged at a distance to one another in multiple positions and the stimulus device (1 ) being configured to time-dependently switch selected ones of the stimulus electrodes (3) from an energized state to a non-energized state and vice versa for time-dependently changing the location of application of the stimulus.
摘要翻译：用于刺激受试者中饱腹感激素释放的系统包括具有电脉冲发生器（2）的刺激装置（11）和适于对受试者的胃肠系统的组织施加电刺激的多个刺激电极（3）刺激电极（3）在多个位置彼此间隔一定距离地布置，并且刺激装置（1）构造成将刺激电极（3）中的所选择的激励电极从激励状态时间依赖地切换到非通电状态，反之亦然，从而随时改变刺激应用的位置。

4. 发明申请

WO2013143603A1 DEVICES AND METHODS FOR THE TREATMENT OF METABOLIC DISORDERS 审中-公开
标题翻译：用于治疗代谢性疾病的装置和方法
公开(公告)号：WO2013143603A1
公开(公告)日：2013-10-03
申请号：PCT/EP2012/055813
申请日：2012-03-30
申请人： ETHICON ENDO-SURGERY, INC. , FELDER, Kevin D. , LONG, Gary L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S.
发明人： FELDER, Kevin D. , LONG, Gary L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S.
IPC分类号： A61N1/05 , A61N1/04 , A61N1/36
CPC分类号： A61N1/0509 , A61N1/0408 , A61N1/0476 , A61N1/36007
摘要： A system for stimulating the release of satiety hormone in a subject includes a stimulus device (1) having an electrical pulse generator (2) and stimulus electrodes (3) adapted to apply an electrical stimulus to a tissue, the stimulus device (1) being adapted to be endoluminally introduced in a gastrointestinal system of the subject, and means (9, 16, 17, 42) for anchoring the stimulus device permanently in a target location inside the gastrointestinal system in a position in which the stimulus electrodes engage a tissue of said gastrointestinal system.
摘要翻译：用于刺激受试者中饱腹感激素释放的系统包括具有电脉冲发生器（2）的刺激装置（1）和适于对组织施加电刺激的刺激电极（3），刺激装置（1）为适于在受试者的胃肠系统中被内窥镜引入，以及用于将刺激装置永久地固定在胃肠系统内的目标位置中的装置（9,16,17,42），其中刺激电极接合刺激电极的组织说胃肠系统。

5. 发明申请

WO2013143608A1 ŁIMPLANTABLE SYSTEM FOR PROVIDING ELECTRICAL STIMULATION IN RESPONSE TO DETECTING AN INGESTION OF FOOD 审中-公开
标题翻译：用于提供电刺激以检测食物摄入的极限系统
公开(公告)号：WO2013143608A1
公开(公告)日：2013-10-03
申请号：PCT/EP2012/055831
申请日：2012-03-30
申请人： ETHICON ENDO-SURGERY, INC. , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S. , HARRIS, Jason , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele
发明人： BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S. , HARRIS, Jason , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/36007 , A61F5/0026 , A61F2005/0016 , A61F2005/002 , A61N1/0509 , A61N1/0517
摘要： An implantable system for stimulating the release of satiety hormone in a subject comprises a stimulus device (11) which is implantable in the subject and adapted to apply an electrical stimulus to a tissue of a gastrointestinal system of said subject, and a detection device (2, 7, 8) which is implantable in the subject and adapted to continuously monitoring at least one of a mechanical characteristic and an electrical characteristic of the subject to detect an ingestion of food by said subject, wherein the detection device cooperates with the stimulus device (11) such that the stimulus device (11) applies said electrical stimulus in response to a detected ingestion of food.
摘要翻译：用于刺激受试者的饱腹感激素释放的可植入系统包括刺激装置（11），所述刺激装置可植入对象并适于对所述受试者的胃肠系统的组织施加电刺激，以及检测装置（2），7,8），其可植入对象中并且适于连续监测所述对象的机械特性和电特性中的至少一个，以检测所述对象摄取食物，其中所述检测装置与所述刺激装置（ 11），使得刺激装置（11）响应于检测到的食物摄取而应用所述电刺激。

6. 发明申请

WO2012087669A1 PILL CATCHERS 审中-公开
公开(公告)号：WO2012087669A1
公开(公告)日：2012-06-28
申请号：PCT/US2011/064634
申请日：2011-12-13
申请人： ETHICON ENDO-SURGERY, INC. , ORTIZ, Mark, S. , HESS, Christopher, J. , HARRIS, Jason, L. , VOEGELE, James, W. , ZEINER, Mark, S. , OVERMYER, Mark, D. , KRAIMER, Joseph, Bernard , SHIMIZU, Jeff , CRIVELLI, Rocco , TARDY, Yanik , UTARD, Thierry , BURGER, Juergen , BORK, Toralf , PFLEIDERER, Martin , CHOSSAT, Olivier
发明人： ORTIZ, Mark, S. , HESS, Christopher, J. , HARRIS, Jason, L. , VOEGELE, James, W. , ZEINER, Mark, S. , OVERMYER, Mark, D. , KRAIMER, Joseph, Bernard , SHIMIZU, Jeff , CRIVELLI, Rocco , TARDY, Yanik , UTARD, Thierry , BURGER, Juergen , BORK, Toralf , PFLEIDERER, Martin , CHOSSAT, Olivier
IPC分类号： A61M31/00 , A61B1/00 , A61F5/00 , A61K9/00 , A61B5/00 , A61J3/00
CPC分类号： A61B1/041 , A61B1/00147 , A61F5/0013 , A61M31/002
摘要： Devices are provided for the controlled delivery of a therapeutic to a targeted location within a body. More particularly, devices are provided for controlling the rate of passage of an orally administered pill through a body, as well as for controlling the delivery of a therapeutic within the pill at a specific location within the body. Various types of devices, generally referred to herein as "catchers," are provided that can actively catch a pill as it passes through a body. The catcher can hold the pill at a specific location within the body until a predetermined event occurs, such as partial or complete administration of a therapeutic within the pill. The catcher can then release the pill upon command and/or upon the occurrence of the predetermined event to allow the pill to pass out of the body. In other embodiments, various types of pills are provided that can actively engage a catcher and remain engaged with the catcher until a predetermined event occurs.
摘要翻译：提供了用于将治疗剂控制递送到体内目标位置的装置。更具体地，提供了用于控制经口施用的药丸通过身体的通过速率的装置，以及用于控制在体内特定位置处的丸剂内的治疗剂的递送。提供了在本文中通常被称为“捕获器”的各种类型的装置，其可以在通过身体时主动地捕捉药丸。捕获器可以将药丸保持在体内的特定位置，直到发生预定事件，例如在丸中部分或完全施用治疗剂。然后，捕手可以在命令和/或发生预定事件时释放药片以允许药丸从身体中流出。在其他实施例中，提供了可以主动地接合捕获器并保持与捕获器接合的各种类型的药丸，直到发生预定事件。

7. 发明申请

WO2014163784A1 MEAL DETECTION DEVICES AND METHODS 审中-公开
标题翻译：食品检测装置和方法
公开(公告)号：WO2014163784A1
公开(公告)日：2014-10-09
申请号：PCT/US2014/016394
申请日：2014-02-14
申请人： ETHICON ENDO-SURGERY, INC.
发明人： DUNKI-JACOBS, Adam , HARRIS, Jason, L. , LEMAY, Mathieu , PFLEIDERER, Martin , PROENCA, Martin , UTARD, Thierry
IPC分类号： A61B5/00 , A61B5/053
CPC分类号： A61B5/4839 , A61B5/01 , A61B5/0402 , A61B5/0488 , A61B5/04884 , A61B5/0537 , A61B5/1107 , A61B5/4238 , A61B5/4836 , A61B5/4866 , A61B7/008 , A61B2505/07 , A61F5/0013 , A61F5/0059 , A61F2005/002 , A61M5/1723 , A61N1/36007 , G06F19/00
摘要： Devices and methods for detecting meal intake are disclosed herein. In some embodiments, one or more sensors can be used to detect or monitor physiological parameters of a user (e.g., heart rate, body movements, temperature, pH, impedance, gastric stretch, sound emissions, and the like). The outputs of the sensors can be received by a computer system configured to analyze the sensor data and make a determination as to whether meal intake has occurred or is presently occurring. The computer system's determination can be used to trigger, modulate, or otherwise control one or more therapeutic devices. Other types of devices can also be controlled using this determination, such as monitoring or logging devices.
摘要翻译：本文公开了用于检测膳食摄入的装置和方法。在一些实施例中，可以使用一个或多个传感器来检测或监测用户的生理参数（例如，心率，身体运动，温度，pH，阻抗，胃伸展，声音发射等）。传感器的输出可以被配置成分析传感器数据的计算机系统接收，并且确定饭食是否已经发生或正在发生。计算机系统的确定可用于触发，调制或以其他方式控制一个或多个治疗装置。也可以使用此确定来控制其他类型的设备，例如监视或记录设备。

8. 发明申请

WO2004026192A1 A DEVICE FOR DELIVERING A SURGICAL IMPLANT 审中-公开
标题翻译：一种用于输送外科植入物的装置
公开(公告)号：WO2004026192A1
公开(公告)日：2004-04-01
申请号：PCT/GB2003/003987
申请日：2003-09-16
申请人： DEPUY INTERNATIONAL LIMITED , PFLEIDERER, Martin , BIRKBECK, Alec
发明人： PFLEIDERER, Martin , BIRKBECK, Alec
IPC分类号： A61F2/46
CPC分类号： A61F2/4611 , A61F2002/30092 , A61F2002/4627 , A61F2210/0014
摘要： A device (10) for delivering a surgical implant (14) comprises a guide track (11) for guiding the movement of a spinal implant (14) to an implantation site. An implant carrier (12) engages the implant in the guide track and can move along the guide track in order to deliver the implant to the implantation site, the carrier (12) including a connector (15) which can be displaced between a connected position in which the implant is connected to the carrier to move with it in the guide track, and a disconnected position in which the implant can be separated from the carrier. A driving device (13) can engage the implant carrier to move the carrier (12) along the track. A formation can cause the connector (15) on the implant carrier (12) to be displaced from the connected to the disconnected position when the carrier reaches a pre-determined position.
摘要翻译：用于输送外科植入物（14）的装置（10）包括用于将脊柱植入物（14）的运动引导到植入部位的导轨（11）。植入物载体（12）将植入物接合在导轨中并且可以沿着导轨移动，以将植入物输送到植入位置，载体（12）包括连接器（15），该连接器可以在连接位置其中植入物连接到载体以与导轨一起移动，以及其中植入物可以与载体分离的断开位置。驱动装置（13）可以接合植入物载体以沿着轨道移动载体（12）。当载体到达预定位置时，地层可以导致植入载体（12）上的连接器（15）从连接到断开位置移位。

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