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1. 发明申请

WO2011149879A2 INTESTINAL BRAKE INDUCING INTRALUMINAL THERAPEUTIC SUBSTANCE ELUTING DEVICES AND METHODS 审中-公开
标题翻译： INTESTINAL BRAKE INDING IN INTRALUMINAL THERAPEUTIC THEAPEUTIC TYSTURE ELDTING ELTERTING DEVICES AND METHODS
公开(公告)号：WO2011149879A2
公开(公告)日：2011-12-01
申请号：PCT/US2011/037660
申请日：2011-05-24
申请人： ETHICON ENDO-SURGERY, INC. , ALBRECHT, Thomas, E. , ALDRIDGE, Jeffrey, L. , BAKOS, Gregory, J. , CROPPER, Michael, S. , HERRERA-DAVIS, Denzel, Z. , DLUGOS, Daniel, F. , HARRIS, Jason, L. , HESS, Christopher, J. , HUNT, John, V. , MALAVIYA, Prasanna , ORTIZ, Mark, S. , OVERMYER, Mark, D. , PASTORELLI, Alessandro , ROBERTSON, Galen, C. , SHELTON, Frederick, E. , STOKES, Michael, J. , THOMPSON, Suzanne , TIMM, Richard, W. , VOEGELE, James, W. , WEISENBURGH, William B., III , WIDENHOUSE, Christopher W. , WIDENHOUSE, Tamara S. Vetro , WOODARD, James A., Jr. , XATES, David C. , ZEINER, Mark S. , ZWOLINSKY, Andrew M.
发明人： ALBRECHT, Thomas, E. , ALDRIDGE, Jeffrey, L. , BAKOS, Gregory, J. , CROPPER, Michael, S. , HERRERA-DAVIS, Denzel, Z. , DLUGOS, Daniel, F. , HARRIS, Jason, L. , HESS, Christopher, J. , HUNT, John, V. , MALAVIYA, Prasanna , ORTIZ, Mark, S. , OVERMYER, Mark, D. , PASTORELLI, Alessandro , ROBERTSON, Galen, C. , SHELTON, Frederick, E. , STOKES, Michael, J. , THOMPSON, Suzanne , TIMM, Richard, W. , VOEGELE, James, W. , WEISENBURGH, William B., III , WIDENHOUSE, Christopher W. , WIDENHOUSE, Tamara S. Vetro , WOODARD, James A., Jr. , XATES, David C. , ZEINER, Mark S. , ZWOLINSKY, Andrew M.
IPC分类号： A61M5/00
CPC分类号： A61F5/0079 , A61K9/0065 , A61M5/14276 , A61M31/002 , A61M39/0208 , A61M2210/106 , A61M2210/1064
摘要： Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices may be accomplished via stabilized implantable systems and ingestible pills. In one aspect, a method of inducing satiety includes implanting an implant within a lumen of a gastrointestinal tract and retaining a portion of chyme that flows by the implant within a body of the implant. The method further involves re-releasing the retained chyme from the implant into the gastrointestinal tract at a predetermined rate slower than a rate caused by natural peristalsis.
摘要翻译：方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。这些方法和装置可以通过稳定的可植入系统和可摄取的药丸来实现。一方面，一种诱导饱腹感的方法包括将植入物植入胃肠道的内腔中，并且将植入物流动的部分保持在植入物的体内。该方法还包括以比由天然蠕动引起的速率慢的预定速率将留置的食糜从植入物再释放到胃肠道中。

2. 发明申请

WO2011149875A2 METHOD OF FILLING AN INTRALUMINAL RESERVOIR WITH A THERAPEUTIC SUBSTANCE 审中-公开
标题翻译：用治疗药物填充血管内储备的方法
公开(公告)号：WO2011149875A2
公开(公告)日：2011-12-01
申请号：PCT/US2011/037653
申请日：2011-05-24
申请人： ETHICON ENDO-SURGERY, INC. , ALDRIDGE, Jeffrey, L. , BAKOS, Gregory, J. , CONLON, Sean, P. , CROPPER, Michael, S. , HERRERA-DAVIS, Denzel, Z. , DLUGOS, Daniel, F. , ELMER, Lucas, B. , HARRIS, Jason, L. , HESS, Christopher, J. , MESSERLY, Jeffrey, D. , ORTIZ, Mark, S. , OVERMYER, Mark, D. , PASTORELLI, Alessandro , STOKES, Michael, J. , STULEN, Foster, B. , THOMPSON, Suzanne , TIMM, Richard, W. , VOEGELE, James, W. , WEANER, Lauren, S. , WEISENBURGH, William, B., II , WIDENHOUSE, Tamara, S. Vetro , WOODARD, James, A., Jr. , ZEINER, Mark, S. , ZWOLINSKI, Andrew, M.
发明人： ALDRIDGE, Jeffrey, L. , BAKOS, Gregory, J. , CONLON, Sean, P. , CROPPER, Michael, S. , HERRERA-DAVIS, Denzel, Z. , DLUGOS, Daniel, F. , ELMER, Lucas, B. , HARRIS, Jason, L. , HESS, Christopher, J. , MESSERLY, Jeffrey, D. , ORTIZ, Mark, S. , OVERMYER, Mark, D. , PASTORELLI, Alessandro , STOKES, Michael, J. , STULEN, Foster, B. , THOMPSON, Suzanne , TIMM, Richard, W. , VOEGELE, James, W. , WEANER, Lauren, S. , WEISENBURGH, William, B., II , WIDENHOUSE, Tamara, S. Vetro , WOODARD, James, A., Jr. , ZEINER, Mark, S. , ZWOLINSKI, Andrew, M.
IPC分类号： A61F2/04 , A61M25/00 , A61M31/00
CPC分类号： A61F5/005 , A61F5/0003 , A61F5/0013 , A61M25/007 , A61M25/04 , A61M31/00 , A61M37/0015
摘要： Methods described herein involve introducing a nasogastric tube into a patient, connecting the nasogastric tube with a reservoir, anchoring the nasogastric tube within the nasal cavity, and introducing a substance into the reservoir through the nasogastric tube.
摘要翻译：本文描述的方法包括将鼻胃管引入患者体内，将鼻胃管与储器连接，将鼻胃管固定在鼻腔内，并通过鼻胃管将物质引入储液器。

4. 发明申请

WO2011084420A1 INTERFACE SYSTEMS FOR AIDING CLINICIANS IN CONTROLLING AND MANIPULATING AT LEAST ONE ENDOSCOPIC SURGICAL INSTRUMENT AND A CABLE CONTROLLED GUIDE TUBE SYSTEM 审中-公开
标题翻译：用于控制和控制至少一个内窥镜手术仪器和电缆控制导管系统的接口系统
公开(公告)号：WO2011084420A1
公开(公告)日：2011-07-14
申请号：PCT/US2010/060288
申请日：2010-12-14
申请人： ETHICON ENDO-SURGERY, INC. , TRUSTY, Robert, M. , VAKHARIA, Omar, J. , BAKOS, Gregory, J. , GUNNERSON, Kory, A. , MOORE, Jayson, G.
发明人： TRUSTY, Robert, M. , VAKHARIA, Omar, J. , BAKOS, Gregory, J. , GUNNERSON, Kory, A. , MOORE, Jayson, G.
IPC分类号： A61B1/01 , A61B1/005
CPC分类号： A61B1/00133 , A61B1/00149 , A61B1/00154 , A61B1/0051 , A61B1/018 , A61B90/50
摘要： Interface systems for interfacing between at least one endoscopic surgical instrument and a cable-controlled guide tube system. Various embodiments include at least one surgical tool docking assembly that is supportable relative to the cable-controlled guide tube system. The surgical tool docking assembly may comprise a cable drive assembly that is operably couplable to the cable-controlled guide system for applying control motions thereto. The surgical tool docking assembly may further comprise at least one tool docking station that is configured to support an endoscopic surgical instrument therein for selective pivotal travel about a first axis and a second axis. The tool docking stations cooperate with corresponding drive shafts for imparting rotary drive motions to the cable drive assembly. Various docking arrangements are disclosed for coupling the cable drive assembly to the cable-controlled guide tube assembly.
摘要翻译：用于在至少一个内窥镜手术器械和电缆控制的导管系统之间进行接口的接口系统。各种实施例包括至少一个可相对于电缆控制的导管系统支撑的手术工具对接组件。外科手术工具对接组件可以包括电缆驱动组件，其可操作地连接到电缆控制的引导系统，用于向其施加控制运动。外科手术工具对接组件还可以包括至少一个工具对接站，其被构造成在其中支撑内窥镜手术器械以围绕第一轴线和第二轴线选择性地枢转行进。工具对接站与相应的驱动轴配合，以将旋转驱动运动传递给电缆驱动组件。公开了用于将电缆驱动组件耦合到电缆控制的导管组件的各种对接装置。

5. 发明申请

WO2008022262A1 GUIDEWIRE STRUCTURE INCLUDING A MEDICAL GUIDEWIRE 审中-公开
标题翻译：包括医疗指南的指导结构
公开(公告)号：WO2008022262A1
公开(公告)日：2008-02-21
申请号：PCT/US2007/076102
申请日：2007-08-16
申请人： ETHICON ENDO-SURGERY, INC , BAKOS, Gregory, J.
发明人： BAKOS, Gregory, J.
IPC分类号： A61M25/09
CPC分类号： A61M25/09 , A61M25/04
摘要： A guidewire structure includes a medical guidewire and an attached guidewire anchor having collapsed and expanded states. The anchor includes struts and defines in the expanded state an open structure. Another guidewire structure includes a medical guidewire, an attached guidewire anchor having collapsed and expanded states, and an overtube. The anchor is resiliently flexible and is resiliently biased to the expanded state. The overtube is adapted to slide over the medical guidewire, to slidably cover and compress the anchor, and to slidably expose the anchor. Another guidewire structure includes a medical guidewire, a guidewire anchor, and a hollow tube having a distal end attached proximate the proximal end of the guidewire anchor. The medical guidewire is positioned within the hollow tube and within the guidewire anchor and is attached proximate the distal end of the anchor. The anchor is flexible and has collapsed and expanded states.
摘要翻译：导丝结构包括医疗导丝和具有折叠和展开状态的附接导丝锚。锚固件包括支柱并且在展开状态中限定开放结构。另一种导丝结构包括医疗导丝，具有折叠和展开状态的附接的导丝锚，以及外套管。该锚具有弹性柔性并被弹性地偏压到膨胀状态。外套管适于在医疗导线上滑动，以可滑动地覆盖和压缩锚固件，并且可滑动地露出锚固件。另一个导丝结构包括医疗导丝，导丝锚和中空管，其中远端附近靠近导丝锚的近端。医疗导丝定位在中空管内并且在导丝锚固件内并且靠近锚的远端附接。锚是灵活的，已经崩溃和扩张状态。

6. 发明申请

WO2008022260A1 GUIDEWIRE STRUCTURE INCLUDING A MEDICAL GUIDEWIRE AND METHOD FOR USING A MEDICAL INSTRUMENT 审中-公开
标题翻译：包括医疗指南的指导结构和使用医用仪器的方法
公开(公告)号：WO2008022260A1
公开(公告)日：2008-02-21
申请号：PCT/US2007/076099
申请日：2007-08-16
申请人： ETHICON ENDO-SURGERY, INC , BAKOS, Gregory, J.
发明人： BAKOS, Gregory, J.
IPC分类号： A61M25/09
CPC分类号： A61M25/09 , A61M2025/09075 , A61M2025/09175 , A61M2205/583
摘要： A first guidewire structure includes a medical guidewire having a working portion which is extendable beyond a distal end of a medical instrument. The working portion has a length, and the working portion is tapered for substantially one-hundred percent of the length. A second guidewire structure includes a medical guidewire having a working portion, wherein the working portion has a length, and wherein the working portion includes a tapered portion for over fifty percent of the length. A third guidewire structure includes a medical guidewire having a working portion.. The working portion has a length, and the working portion includes a plurality of lengthwise-adjoining segment pairs for over fifty percent of the length. Each segment pair consists essentially of a non-tapered segment having a substantially constant cross section and a tapered segment lengthwise adjoining the non-tapered segment. Methods are described for using medical instruments having the guidewire structures.
摘要翻译：第一导丝结构包括具有可延伸超过医疗器械的远端的工作部分的医疗导丝。工作部分具有长度，工作部分的长度大致为百分之一百。第二导丝结构包括具有工作部分的医疗导丝，其中所述工作部分具有长度，并且其中所述工作部分包括超过所述长度的百分之五十的锥形部分。第三导线结构包括具有工作部分的医疗导丝。工作部分具有一定的长度，并且工作部分包括长度超过百分之五十的多个纵向相邻的段对。每个段对基本上由具有基本恒定横截面的非锥形段和与非锥形段相邻的锥形段组成。描述了使用具有导丝结构的医疗器械的方法。

7. 发明申请

WO2011056848A1 KITS AND PROCEDURES FOR NATURAL ORIFICE TRANSLUMENAL ENDOSCOPIC SURGERY 审中-公开
标题翻译：自然手术治疗内镜手术的手套和手术
公开(公告)号：WO2011056848A1
公开(公告)日：2011-05-12
申请号：PCT/US2010/055267
申请日：2010-11-03
申请人： ETHICON ENDO-SURGERY, INC. , GHABRIAL, Ragae, M. , SPIVEY, James, T. , BALLY, Kurt, R. , LINENKUGEL, Duane, A. , BAKOS, Gregory, J. , CARROLL, Kempton, K. , VAKHARIA, Omar, J. , TRUSTY, Robert, M.
发明人： GHABRIAL, Ragae, M. , SPIVEY, James, T. , BALLY, Kurt, R. , LINENKUGEL, Duane, A. , BAKOS, Gregory, J. , CARROLL, Kempton, K. , VAKHARIA, Omar, J. , TRUSTY, Robert, M.
IPC分类号： A61B17/34 , A61B1/005 , A61B17/00 , A61B17/04 , A61M25/10 , A61B17/128 , A61B17/32 , A61B18/14 , A61B17/29
CPC分类号： A61B17/3478 , A61B1/00135 , A61B1/00154 , A61B1/018 , A61B17/1285 , A61B17/320016 , A61B17/32056 , A61B17/3421 , A61B17/3423 , A61B18/1442 , A61B2017/00278 , A61B2017/00287 , A61B2017/003 , A61B2017/00336 , A61B2017/00358 , A61B2017/0412 , A61B2017/0417 , A61B2017/0437 , A61B2017/0438 , A61B2017/0464 , A61B2017/2905 , A61B2017/2908 , A61B2017/2927 , A61B2017/2936 , A61B2017/2939 , A61B2017/3445 , A61M25/0084 , A61M25/0102 , A61M25/0133 , A61M25/0136 , A61M25/10 , A61M29/02 , A61M2025/0681 , A61M2025/1093
摘要： Various surgical devices, kits, and/or methods are provided herein that may be useful in performing a surgical procedure through a natural orifice. Such a surgical procedure may utilize one or more devices, kits, and/or methods to create an access port to a body cavity of a patient, to perform a specific surgical procedure, and to close the access port. In various embodiments, the specific surgical procedure may comprise a sleeve gastrectomy, a ventral hernia repair, a hybrid transgastric cholecystectomy, and/or a hybrid transgastric appendectomy.
摘要翻译：本文提供的各种手术装置，试剂盒和/或方法可用于通过天然孔进行外科手术。这种外科手术可以利用一个或多个装置，套件和/或方法来创建到患者的体腔的进入端口，以执行特定的外科手术并且关闭进入端口。在各种实施例中，具体的外科手术可以包括套管胃切除术，腹侧疝修补术，混合性经胃胆囊切除术和/或混合性经胃阑尾切除术。

8. 发明申请

WO2005113055A2 MEDICAL INSTRUMENT HAVING A CONTROLLED GUIDEWIRE DRIVE 审中-公开
标题翻译：具有控制引导装置的医用仪器
公开(公告)号：WO2005113055A2
公开(公告)日：2005-12-01
申请号：PCT/US2005/016858
申请日：2005-05-13
申请人： ETHICON ENDO-SURGERY, INC. , LONG, Gary, L. , BAKOS, Gregory, J. , VAKHARIA, Omar, J.
发明人： LONG, Gary, L. , BAKOS, Gregory, J. , VAKHARIA, Omar, J.
IPC分类号： A61M25/01
CPC分类号： A61B1/00133 , A61B2017/00398 , A61M25/0113 , A61M25/0136 , A61M25/09 , A61M25/09041 , A61M2025/09183
摘要： A medical instrument includes a flexible catheter, a medical guidewire, and a mechanized guidewire drive assembly. The catheter has a distal end insertable into a body lumen of a patient. The mechanized guidewire drive assembly is adapted for operable engagement with the medical guidewire. The mechanized guidewire drive assembly includes a motor and includes a controller which drives the motor with a driving force. The driving force has a predetermined upper limit.
摘要翻译：医疗器械包括柔性导管，医疗导丝和机械化导丝驱动组件。导管具有可插入患者体腔的远端。机械化导丝驱动组件适于与医疗导线可操作地接合。机械化导丝驱动组件包括马达并且包括用驱动力驱动马达的控制器。驱动力具有预定的上限。

9. 发明申请

WO2005112786A2 T-TYPE SUTURE ANCHORING DEVICES AND METHODS OF USING SAME 审中-公开
标题翻译： T型锚固装置及其使用方法
公开(公告)号：WO2005112786A2
公开(公告)日：2005-12-01
申请号：PCT/US2005/016618
申请日：2005-05-12
申请人： ETHICON ENDO-SURGERY, INC. , NOBIS, Rudolph, H. , SWAIN, Christopher, Paul , JANKOSKI, Frank , VAKHARIA, Omar, J. , FAUX, John, A. , BAKOS, Gregory, J. , LINENKUGEL, Duane, A.
发明人： NOBIS, Rudolph, H. , SWAIN, Christopher, Paul , JANKOSKI, Frank , VAKHARIA, Omar, J. , FAUX, John, A. , BAKOS, Gregory, J. , LINENKUGEL, Duane, A.
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B17/0467 , A61B17/0469 , A61B17/0487 , A61B17/06166 , A61B2017/0409 , A61B2017/0417 , A61B2017/0445 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0458 , A61B2017/0464 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052
摘要： Suture anchoring devices are disclosed, including a T-tag, anchoring device that is suitably small enough to fit into the hollow tip of a needle and, furthermore, provide protection to the suture against being cut or otherwise damaged by the sharp edge of the needle tip. One disclosed device includes a slot for providing a pivot point between the suture and the body when deployed, which can be employed to form a T-tag.
摘要翻译：公开了缝合线锚定装置，包括T形标签，适当地足够小以适合于针的中空尖端的锚固装置，此外，为缝合线提供保护以防止被针尖的尖锐边缘切割或以其它方式损伤小费。一个公开的装置包括用于在展开时在缝合线和主体之间提供枢轴点的槽，其可用于形成T形标签。

10. 发明申请

WO2012118659A1 ELECTRICAL ABLATION DEVICES AND METHODS 审中-公开
标题翻译：电气设备和方法
公开(公告)号：WO2012118659A1
公开(公告)日：2012-09-07
申请号：PCT/US2012/026049
申请日：2012-02-22
申请人： ETHICON ENDO-SURGERY, INC. , LONG, Gary, L. , PLESCIA, David, N. , BAKOS, Gregory, J.
发明人： LONG, Gary, L. , PLESCIA, David, N. , BAKOS, Gregory, J.
IPC分类号： A61N1/32 , A61B18/14
CPC分类号： A61N1/327 , A61B18/1206 , A61B18/1492 , A61B18/1815 , A61B2018/00613 , A61B2018/00642 , A61B2018/00672 , A61B2018/00678 , A61B2018/00708 , A61B2018/00791 , A61B2090/064
摘要： An electrical ablation device may generally comprise first and second electrodes coupled to an energy source operative to generate and deliver a first sequence of electrical pulses and a second sequence of electrical pulses to tissue having a necrotic threshold, wherein the first sequence of electrical pulses delivers a first energy dose that is less than the necrotic threshold to induce thermal heating in the tissue and the second sequence of electrical pulses delivers a second energy dose equal to or greater than the necrotic threshold to induce cell necrosis in the tissue by irreversible electroporation. The first sequence of electrical pulses may each be independently characterized by a first amplitude, a first pulse width, and a first frequency. The second sequence of electrical pulses may be characterized by a second amplitude, a second pulse width, and a second frequency.
摘要翻译：电消融装置通常可以包括耦合到能量源的第一和第二电极，其能够产生并递送电脉冲的第一序列和第二电脉冲序列到具有坏死阈值的组织，其中电脉冲的第一序列递送第一能量剂量小于坏死阈值以诱导组织中的热加热，第二电脉冲序列传递等于或大于坏死阈值的第二能量剂量，以通过不可逆电穿孔诱导组织中的细胞坏死。电脉冲的第一序列可以各自独立地以第一幅度，第一脉冲宽度和第一频率为特征。电脉冲的第二序列可以由第二幅度，第二脉冲宽度和第二频率表征。

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