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1. 发明申请

WO2011149876A3 METHODS AND DEVICES FOR THE REROUTING OF CHYME TO INDUCT INTESTINAL BRAKE 审中-公开
标题翻译：用于搅拌CHYME以诱导内脏制动的方法和装置
公开(公告)号：WO2011149876A3
公开(公告)日：2012-10-04
申请号：PCT/US2011037657
申请日：2011-05-24
申请人： ETHICON ENDO SURGERY INC , ALBRECHT THOMAS E , ALDRIDGE JEFFREY L , CONLON SEAN P , CROPPER MICHAEL S , HERRERA-DAVIS DENZEL Z , DLUGOS DANIEL F JR , HARRIS JASON L , HESS CHRISTOPHER J , HOUSER KEVIN L , GUTIERREZ MARIO , MALAVIYA PRASANNA , MARCOTTE AMY L , MESSERLY JEFFREY D , NGUYEN ANTHONY , ORTIZ MARK S , OVERMYER MARK D , PASTORELLI ALESSANDRO , ROBERTSON GALEN C , SHELTON FREDERICK E IV , STOKES MICHAEL J , STULEN FOSTER B , VOEGELE JAMES W , WEANER LAUREN S , WIDENHOUSE TAMARA S VETRO , WOODARD JAMES A JR , ZEINER MARK S
发明人： ALBRECHT THOMAS E , ALDRIDGE JEFFREY L , CONLON SEAN P , CROPPER MICHAEL S , HERRERA-DAVIS DENZEL Z , DLUGOS DANIEL F JR , HARRIS JASON L , HESS CHRISTOPHER J , HOUSER KEVIN L , GUTIERREZ MARIO , MALAVIYA PRASANNA , MARCOTTE AMY L , MESSERLY JEFFREY D , NGUYEN ANTHONY , ORTIZ MARK S , OVERMYER MARK D , PASTORELLI ALESSANDRO , ROBERTSON GALEN C , SHELTON FREDERICK E IV , STOKES MICHAEL J , STULEN FOSTER B , VOEGELE JAMES W , WEANER LAUREN S , WIDENHOUSE TAMARA S VETRO , WOODARD JAMES A JR , ZEINER MARK S
IPC分类号： A61F2/04 , A61F5/00
CPC分类号： A61B17/00234 , A61B5/0031 , A61B5/036 , A61B5/073 , A61B5/076 , A61B5/1107 , A61B5/14532 , A61B5/14539 , A61B5/42 , A61B17/0469 , A61B17/1114 , A61B2017/00876 , A61B2017/1117 , A61B2017/1139 , A61B2560/0219 , A61F2/04 , A61F5/0013 , A61F2002/045
摘要： Methods and devices reroute chyme to induce intestinal brake in order to improve the effectiveness of bariatric surgical procedures and to improve comorbidity resolution. A bowel is manipulated to provide a shortened path for chyme to travel to the ileum. These methods and devices of rerouting chyme to induce intestinal brake may comprise one or more of a surgical procedure, an implanted device, or a combination of an implant with an improved surgical procedure.
摘要翻译：方法和装置重新路由食糜诱导肠道制动，以提高减肥手术的有效性和改善共病分解。肠道被操纵以提供用于食糜行进到回肠的缩短路径。用于诱导肠内制动器的重新路由食糜的这些方法和装置可以包括外科手术，植入装置或具有改进的外科手术的植入物的组合中的一种或多种。

2. 发明申请

WO2012087724A1 ENDOLUMINAL FOLD CREATION 审中-公开
公开(公告)号：WO2012087724A1
公开(公告)日：2012-06-28
申请号：PCT/US2011/065027
申请日：2011-12-15
申请人： ETHICON ENDO-SURGERY, INC. , STOKES, Michael, J. , ZEINER, Mark, S. , HARRIS, Jason, L. , LONG, Gary, L.
发明人： STOKES, Michael, J. , ZEINER, Mark, S. , HARRIS, Jason, L. , LONG, Gary, L.
IPC分类号： A61B17/04 , A61B17/12 , A61B17/128 , A61B18/14 , A61B17/00 , A61B17/30 , A61B18/08 , A61B17/072 , A61N7/02
CPC分类号： A61B18/1492 , A61B17/00234 , A61B18/08 , A61B2017/00296 , A61B2017/00349 , A61B2017/00353 , A61B2017/00818 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0488 , A61B2017/06052 , A61B2017/07221 , A61B2017/12018 , A61B2017/306 , A61B2018/00279 , A61B2018/00494 , A61B2018/0063 , A61B2018/142 , A61B2018/143 , A61F5/0083 , A61N7/022
摘要： Devices and methods are provided for forming one or more plications in the walls of a body cavity. In particular, endoscopic devices and methods are provided for forming and/or securing endoluminal tissue folds to reduce the volume of the gastric cavity. An end effector that includes a tissue receiving cavity can be delivered to a desired surgical site to allow a tissue fold to be formed within the tissue receiving cavity. A fastener can be used to secure the adjacent layers of tissue that form the tissue fold. The tissue folds can be effective to limit the stomach's capacity and create a feeling of satiety.
摘要翻译：提供了用于在体腔的壁中形成一个或多个褶皱的装置和方法。具体而言，提供了用于形成和/或固定腔内组织褶皱以减少胃腔体积的内窥镜装置和方法。包括组织接收腔的末端执行器可被递送到期望的手术部位，以允许在组织接收腔内形成组织折叠。紧固件可用于固定形成组织褶皱的相邻组织层。组织褶皱可以有效地限制胃的能力，并产生饱腹感。

3. 发明申请

WO2011149885A3 SYSTEMS AND METHODS FOR GASTRIC VOLUME REGULATION 审中-公开
标题翻译：用于胃体积调节的系统和方法
公开(公告)号：WO2011149885A3
公开(公告)日：2012-05-10
申请号：PCT/US2011037668
申请日：2011-05-24
申请人： ETHICON ENDO SURGERY INC , ALDRIDGE JEFFREY L , CROPPER MICHAEL S , HERRERA-DAVIS DENZEL Z , DLUGOS DANIEL F , HARRIS JASON L , HUNT JOHN V , MALAVIYA PRASANNA , MESSERLY JEFFREY D , ORTIZ MARK S , OVERMYER MARK D , ROBERTSON GALEN C , SHELTON FREDERICK E IV , STULEN FOSTER B , THOMPSON SUSAN , VOEGELE JAMES W , WIDENHOUSE CHRISTOPHER W , WIDENHOUSE TAMARA S VETRO , YATES DAVID C , ZEINER MARK S
发明人： ALDRIDGE JEFFREY L , CROPPER MICHAEL S , HERRERA-DAVIS DENZEL Z , DLUGOS DANIEL F , HARRIS JASON L , HUNT JOHN V , MALAVIYA PRASANNA , MESSERLY JEFFREY D , ORTIZ MARK S , OVERMYER MARK D , ROBERTSON GALEN C , SHELTON FREDERICK E IV , STULEN FOSTER B , THOMPSON SUSAN , VOEGELE JAMES W , WIDENHOUSE CHRISTOPHER W , WIDENHOUSE TAMARA S VETRO , YATES DAVID C , ZEINER MARK S
IPC分类号： A61F5/00 , A61B17/29
CPC分类号： A61F5/0083 , A61F5/003 , A61F5/0033 , A61F5/0036 , A61F5/004 , A61F5/0043 , A61F5/005 , A61F5/0053 , A61F5/0056 , A61F5/0073 , A61F5/0086
摘要： Devices and methods for modifying stomach volume include the formation of intragastric slots for wrapping one or more portions of the fundus therethrough with minimal interference with nerves and vasculature flow. Intragastric space occupying devices expand with environmental changes brought about by natural conditions inherent to the digestive cycle such as with changes in pH. Extragastric volume occupying balloons are placed into folded stomach sections. The balloons are fluidly coupled to external gastric filling devices. In yet another set of embodiments, methods and devices provide adjustable gastric volume reduction fundal wraps. In one embodiment, a device is placed in the fundus for Nissen fundoplication and permits postoperative adjustment to reach desired weight loss. Intragastric and extragastric balloons are optionally incorporated.
摘要翻译：用于改变胃体积的装置和方法包括形成胃内槽，用于以最小的神经和脉管系统流动的干扰来包裹眼底的一个或多个部分。内部空间占据装置随着消化循环固有的自然条件（如pH变化）带来的环境变化而扩大。腹腔积气囊放置在折叠的胃部。气囊流体地联接到外部胃灌注装置。在又一组实施方案中，方法和装置提供可调节的胃体积减少基底包裹。在一个实施例中，将装置放置在眼底以进行尼森眼底切开术，并允许术后调整以达到期望的体重减轻。腹腔内和胃内气囊任选并入。

4. 发明申请

WO2011150033A1 ENTEROENDOCRINE MANIPULATION FOR METABOLIC EFFECT 审中-公开
标题翻译： ENTEROENDOCRINE操作代谢效应
公开(公告)号：WO2011150033A1
公开(公告)日：2011-12-01
申请号：PCT/US2011/037869
申请日：2011-05-25
申请人： ETHICON ENDO-SURGERY, INC. , UNIVERSITY OF CINCINNATI , BAKOS, Gregory , CHEKAN, Edward, G. , HERRERA-DAVIS, Denzel, Z. , HARRIS, Jason, L. , LONG, Gary, L. , NOBIS, Rudolph, H. , ORTIZ, Mark, S. , OVERMYER, Mark, D. , PLESCIA, David, N. , SEELEY, Randy, J. , WEISENBURGH, William, B. , WIDENHOUSE, Tamara, S. Vetro , ZEINER, Mark, S. , ZWOLINSKI, Andrew, M.
发明人： BAKOS, Gregory , CHEKAN, Edward, G. , HERRERA-DAVIS, Denzel, Z. , HARRIS, Jason, L. , LONG, Gary, L. , NOBIS, Rudolph, H. , ORTIZ, Mark, S. , OVERMYER, Mark, D. , PLESCIA, David, N. , SEELEY, Randy, J. , WEISENBURGH, William, B. , WIDENHOUSE, Tamara, S. Vetro , ZEINER, Mark, S. , ZWOLINSKI, Andrew, M.
IPC分类号： C12N5/071 , A61K35/38 , A61P1/00 , A61L27/38
CPC分类号： C12N5/0679 , A61K35/12 , A61K35/38 , A61L27/14 , A61L27/3882 , A61L27/58 , A61L31/04 , A61L31/148 , A61L31/16 , A61L2300/64
摘要： L-cells may be introduced in the gastrointestinal tract. L-cells are used in the digestive process to produce a more efficient and lasting means of regulating feelings of satiation in a patient. Desired metabolic effects may be achieved by manipulating L-cells via delivery sites, frequency of delivery, or type of biological substance delivered.
摘要翻译： L细胞可能被引入胃肠道。 L细胞用于消化过程，以产生更有效和持久的调节患者饱腹感的手段。所需的代谢作用可以通过经由递送部位操纵L细胞，递送频率或递送的生物物质的类型来实现。

5. 发明申请

WO2011149882A3 SYSTEMS AND METHODS FOR GASTRIC VOLUME REGULATION 审中-公开
公开(公告)号：WO2011149882A3
公开(公告)日：2011-12-01
申请号：PCT/US2011/037665
申请日：2011-05-24
申请人： ETHICON ENDO-SURGERY, INC. , ALDRIDGE, Jeffrey, L. , CROPPER, Michael, S. , HERRERA-DAVIS, Denzel, Z. , DLUGOS, Daniel, F., Jr. , HARRIS, Jason, L. , HUNT, John, V. , MALAVIYA, Prasanna , MESSERLY, Jeffrey, D. , ORTIZ, Mark, S. , OVERMYER, Mark, D. , ROBERTSON, Galen, C. , SHELTON, Frederick, E., IV , STULEN, Foster, B. , THOMPSON, Suzanne , VOEGELE, James, W. , WEANER, Lauren, S. , WIDENHOUSE, Christopher, W. , WIDENHOUSE, Tamara, S., Vetro , YATES, David, C. , ZEINER, Mark, S.
发明人： ALDRIDGE, Jeffrey, L. , CROPPER, Michael, S. , HERRERA-DAVIS, Denzel, Z. , DLUGOS, Daniel, F., Jr. , HARRIS, Jason, L. , HUNT, John, V. , MALAVIYA, Prasanna , MESSERLY, Jeffrey, D. , ORTIZ, Mark, S. , OVERMYER, Mark, D. , ROBERTSON, Galen, C. , SHELTON, Frederick, E., IV , STULEN, Foster, B. , THOMPSON, Suzanne , VOEGELE, James, W. , WEANER, Lauren, S. , WIDENHOUSE, Christopher, W. , WIDENHOUSE, Tamara, S., Vetro , YATES, David, C. , ZEINER, Mark, S.
IPC分类号： A61F5/00 , A61B17/29
摘要： Devices and methods for modifying stomach volume include the formation of intragastric slots for wrapping one or more portions of the fundus therethrough with minimal interference with nerves and vasculature flow. Intragastric space occupying devices expand with environmental changes brought about by natural conditions inherent to the digestive cycle such as with changes in pH. Extragastric volume occupying balloons are placed into folded stomach sections. The balloons are fluidly coupled to external gastric filling devices. In yet another set of embodiments, methods and devices provide adjustable gastric volume reduction fundal wraps. In one embodiment, a device is placed in the fundus for Nissen fundoplication and permits postoperative adjustment to reach desired weight loss. Intragastric and extragastric balloons are optionally incorporated.

6. 发明申请

WO2011149876A2 METHODS AND DEVICES FOR THE REROUTING OF CHYME TO INDUCT INTESTINAL BRAKE 审中-公开
标题翻译：用于搅拌CHYME以诱导内脏制动的方法和装置
公开(公告)号：WO2011149876A2
公开(公告)日：2011-12-01
申请号：PCT/US2011/037657
申请日：2011-05-24
申请人： ETHICON ENDO-SURGERY, INC. , ALBRECHT, Thomas, E. , ALDRIDGE, Jeffrey, L. , CONLON, Sean, P. , CROPPER, Michael, S. , HERRERA-DAVIS, Denzel, Z. , DLUGOS, Daniel, F., Jr. , HARRIS, Jason, L. , HESS, Christopher, J. , HOUSER, Kevin, L. , GUTIERREZ, Mario , MALAVIYA, Prasanna , MARCOTTE, Amy, L. , MESSERLY, Jeffrey, D. , NGUYEN, Anthony , ORTIZ, Mark, S. , OVERMYER, Mark, D. , PASTORELLI, Alessandro , ROBERTSON, Galen, C. , SHELTON, Frederick, E., IV , STOKES, Michael, J. , STULEN, Foster, B. , VOEGELE, James, W. , WEANER, Lauren, S. , WIDENHOUSE, Tamara, S., Vetro , WOODARD, James, A., Jr. , ZEINER, Mark, S.
发明人： ALBRECHT, Thomas, E. , ALDRIDGE, Jeffrey, L. , CONLON, Sean, P. , CROPPER, Michael, S. , HERRERA-DAVIS, Denzel, Z. , DLUGOS, Daniel, F., Jr. , HARRIS, Jason, L. , HESS, Christopher, J. , HOUSER, Kevin, L. , GUTIERREZ, Mario , MALAVIYA, Prasanna , MARCOTTE, Amy, L. , MESSERLY, Jeffrey, D. , NGUYEN, Anthony , ORTIZ, Mark, S. , OVERMYER, Mark, D. , PASTORELLI, Alessandro , ROBERTSON, Galen, C. , SHELTON, Frederick, E., IV , STOKES, Michael, J. , STULEN, Foster, B. , VOEGELE, James, W. , WEANER, Lauren, S. , WIDENHOUSE, Tamara, S., Vetro , WOODARD, James, A., Jr. , ZEINER, Mark, S.
IPC分类号： A61B17/00 , A61F2/04
CPC分类号： A61B17/00234 , A61B5/0031 , A61B5/036 , A61B5/073 , A61B5/076 , A61B5/1107 , A61B5/14532 , A61B5/14539 , A61B5/42 , A61B17/0469 , A61B17/1114 , A61B2017/00876 , A61B2017/1117 , A61B2017/1139 , A61B2560/0219 , A61F2/04 , A61F5/0013 , A61F2002/045
摘要： Methods and devices reroute chyme to induce intestinal brake in order to improve the effectiveness of bariatric surgical procedures and to improve comorbidity resolution. A bowel is manipulated to provide a shortened path for chyme to travel to the ileum. These methods and devices of rerouting chyme to induce intestinal brake may comprise one or more of a surgical procedure, an implanted device, or a combination of an implant with an improved surgical procedure.
摘要翻译：方法和装置重新路由食糜诱导肠道制动，以提高减肥手术的有效性和改善共病分解。肠道被操纵以提供用于食糜行进到回肠的缩短路径。用于诱导肠内制动器的重新路由食糜的这些方法和装置可以包括外科手术，植入装置或具有改进的外科手术的植入物的组合中的一种或多种。

7. 发明申请

WO2011149875A2 METHOD OF FILLING AN INTRALUMINAL RESERVOIR WITH A THERAPEUTIC SUBSTANCE 审中-公开
标题翻译：用治疗药物填充血管内储备的方法
公开(公告)号：WO2011149875A2
公开(公告)日：2011-12-01
申请号：PCT/US2011/037653
申请日：2011-05-24
申请人： ETHICON ENDO-SURGERY, INC. , ALDRIDGE, Jeffrey, L. , BAKOS, Gregory, J. , CONLON, Sean, P. , CROPPER, Michael, S. , HERRERA-DAVIS, Denzel, Z. , DLUGOS, Daniel, F. , ELMER, Lucas, B. , HARRIS, Jason, L. , HESS, Christopher, J. , MESSERLY, Jeffrey, D. , ORTIZ, Mark, S. , OVERMYER, Mark, D. , PASTORELLI, Alessandro , STOKES, Michael, J. , STULEN, Foster, B. , THOMPSON, Suzanne , TIMM, Richard, W. , VOEGELE, James, W. , WEANER, Lauren, S. , WEISENBURGH, William, B., II , WIDENHOUSE, Tamara, S. Vetro , WOODARD, James, A., Jr. , ZEINER, Mark, S. , ZWOLINSKI, Andrew, M.
发明人： ALDRIDGE, Jeffrey, L. , BAKOS, Gregory, J. , CONLON, Sean, P. , CROPPER, Michael, S. , HERRERA-DAVIS, Denzel, Z. , DLUGOS, Daniel, F. , ELMER, Lucas, B. , HARRIS, Jason, L. , HESS, Christopher, J. , MESSERLY, Jeffrey, D. , ORTIZ, Mark, S. , OVERMYER, Mark, D. , PASTORELLI, Alessandro , STOKES, Michael, J. , STULEN, Foster, B. , THOMPSON, Suzanne , TIMM, Richard, W. , VOEGELE, James, W. , WEANER, Lauren, S. , WEISENBURGH, William, B., II , WIDENHOUSE, Tamara, S. Vetro , WOODARD, James, A., Jr. , ZEINER, Mark, S. , ZWOLINSKI, Andrew, M.
IPC分类号： A61F2/04 , A61M25/00 , A61M31/00
CPC分类号： A61F5/005 , A61F5/0003 , A61F5/0013 , A61M25/007 , A61M25/04 , A61M31/00 , A61M37/0015
摘要： Methods described herein involve introducing a nasogastric tube into a patient, connecting the nasogastric tube with a reservoir, anchoring the nasogastric tube within the nasal cavity, and introducing a substance into the reservoir through the nasogastric tube.
摘要翻译：本文描述的方法包括将鼻胃管引入患者体内，将鼻胃管与储器连接，将鼻胃管固定在鼻腔内，并通过鼻胃管将物质引入储液器。

8. 发明申请

WO2009158468A3 AN IMPLANTABLE DEVICE FOR THE TREATMENT OF OBESITY 审中-公开
标题翻译：用于治疗肥胖的可植入装置
公开(公告)号：WO2009158468A3
公开(公告)日：2010-02-18
申请号：PCT/US2009048609
申请日：2009-06-25
申请人： ETHICON ENDO SURGERY INC , ALBRECHT THOMAS E , ZEINER MARK S
发明人： ALBRECHT THOMAS E , ZEINER MARK S
IPC分类号： A61F5/00
CPC分类号： A61F5/0036 , A61F5/0089
摘要： An implant (10) for placement within a hollow body organ. The implant has a member (14) with distal and proximal ends. The member has an undeployed shape for delivery to the hollow body and a deployed shape for implantation therein. The implant has at least one tensioning tether (80) with a first end attached to at least one of the distal and proximal end and a second ends attached to the member between the distal and proximal ends. Wherein applying tension to the tether moves the member towards the deployed shape. The member preferably has a first rate at which it initially resists bending, and a second substantially higher rate at which it resists further bending.
摘要翻译：用于放置在中空体器官内的植入物（10）。植入物具有远端和近端的构件（14）。该构件具有用于输送到中空体的未部署形状和用于植入其中的展开形状。所述植入物具有至少一个张紧系绳（80），其第一端连接到远端和近端中的至少一个，以及附接到远端和近端之间的构件的第二端。其中向系绳施加张力使构件朝向展开的形状移动。该构件优选地具有其初始抗弯曲的第一速率，以及第二速率抵抗进一步弯曲的第二速率。

10. 发明申请

WO2012103291A1 A SURGICAL STAPLER FASTENING DEVICE 审中-公开
标题翻译：外科手术器械紧固装置
公开(公告)号：WO2012103291A1
公开(公告)日：2012-08-02
申请号：PCT/US2012/022656
申请日：2012-01-26
申请人： ETHICON ENDO-SURGERY, INC. , HOLCOMB, Matthew D. , HARRIS, Jason L. , STOKES, Michael J. , ZEINER, Mark S. , O'KEEFE, Jonathan B. , BOUDREAU, Keith D. , CERIER, Jeffrey C.
发明人： HOLCOMB, Matthew D. , HARRIS, Jason L. , STOKES, Michael J. , ZEINER, Mark S. , O'KEEFE, Jonathan B. , BOUDREAU, Keith D. , CERIER, Jeffrey C.
IPC分类号： A61B17/068 , A61B17/04 , A61B17/00 , A61B17/072
CPC分类号： A61B17/0684 , A61B17/0644 , A61B17/0682 , A61B2017/0053 , A61B2017/00818 , A61B2017/0488 , A61B2017/0645 , A61B2017/0725
摘要： A fastener applying device including a staple housing having a proximal end attached to a handle, a distal end, and a longitudinal axis therebetween. There is at least one fastener within the housing. The device also includes an anvil movable within the staple housing. The anvil has a proximal position and a distal position, wherein when in the distal position a distal end of the anvil extends distal to the distal end of the staple housing by a distance. The device also includes an adjustment nut connecting the staple housing to the handle. Rotation of the adjustment nut changes the distance.
摘要翻译：一种紧固件施加装置，包括具有附接到手柄的近端的钉仓，其远端和它们之间的纵向轴线。壳体内至少有一个紧固件。该装置还包括可在钉仓内移动的砧座。砧座具有近端位置和远端位置，其中当远端位置时，砧座的远端远离钉钉仓的远端延伸一定距离。该装置还包括将钉仓与手柄连接的调节螺母。调整螺母的旋转会改变距离。

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