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1. 发明授权

US5669790A Lead lumen sealing device 失效
标题翻译：铅流明密封装置
公开(公告)号：US5669790A
公开(公告)日：1997-09-23
申请号：US568708
申请日：1995-12-07
申请人： Dean F. Carson , Richard J. Gable
发明人： Dean F. Carson , Richard J. Gable
IPC分类号： A61N1/05 , A61N1/375 , H01R4/36 , H01R13/24 , H01R13/52 , H01R17/18
CPC分类号： A61N1/056 , A61N1/3752 , H01R13/5224 , H01R13/24 , H01R13/5205 , H01R4/36 , Y10S439/909 , Y10S439/948
摘要： A lead sealing device that resides within the connector cavity of a pacemaker or defibrillator intended to prevent fluid intrusion by automatically sealing the lead lumen when the lead connector is inserted. The sealing mechanism may be in the form of a silicone disk located at the base of the space defined by the connector cavity in which the lead is inserted to make electrical and physical contact. It may be fixedly located at the bottom of the connector cavity, or may be a movable plug located within the connector cavity at a location other than the bottom of the cavity, such as adjacent to the connector block. In that case, the pin will make contact with the movable plug immediately after passing through the connector block, and will remain in contact with and seal the lead lumen while the pin and plug are further advanced to bring the pin into its final location to make electrical contact with the connector contact.
摘要翻译：引线密封装置位于起搏器或除颤器的连接器腔内，旨在通过在插入导线连接器时自动密封引流管腔来防止流体侵入。密封机构可以是位于由连接器腔限定的空间的底部的硅树脂的形式，其中铅插入其中以进行电和物理接触。它可以固定地位于连接器腔的底部，或者可以是位于连接器空腔内的除了腔的底部之外的位置的可移动的插塞，例如邻近连接器块。在这种情况下，引脚将在通过连接器块之后立即与可动插头接触，并且在引脚和插头进一步前进以使引脚进入其最终位置时将保持接触并密封引线管腔与连接器触点电接触。

2. 发明授权

US5720631A Lead lumen sealing device 失效
标题翻译：铅流明密封装置
公开(公告)号：US5720631A
公开(公告)日：1998-02-24
申请号：US850882
申请日：1997-05-02
申请人： Dean F. Carson , Richard J. Gable
发明人： Dean F. Carson , Richard J. Gable
IPC分类号： A61N1/05 , A61N1/375 , H01R4/36 , H01R13/24 , H01R13/52 , H01R17/18
CPC分类号： A61N1/056 , A61N1/3752 , H01R13/5224 , H01R13/24 , H01R13/5205 , H01R4/36 , Y10S439/909 , Y10S439/948
摘要： A lead sealing device that resides within the connector cavity of a pacemaker or defibrillator intended to prevent fluid intrusion by automatically sealing the lead lumen when the lead connector is inserted. The sealing mechanism may be in the form of a silicone disk located at the base of the space defined by the connector cavity in which the lead is inserted to make electrical and physical contact. It may be fixedly located at the bottom of the connector cavity, or may be a movable plug located within the connector cavity at a location other than the bottom of the cavity, such as adjacent to the connector block. In that case, the pin will make contact with the movable plug immediately after passing through the connector block, and will remain in contact with and seal the lead lumen while the pin and plug are further advanced to bring the pin into its final location to make electrical contact with the connector contact.
摘要翻译：引线密封装置位于起搏器或除颤器的连接器腔内，旨在通过在插入导线连接器时自动密封引流管腔来防止流体侵入。密封机构可以是位于由连接器腔限定的空间的底部的硅树脂的形式，其中铅插入其中以进行电和物理接触。它可以固定地位于连接器腔的底部，或者可以是位于连接器空腔内的除了腔的底部之外的位置的可移动的插塞，例如邻近连接器块。在这种情况下，引脚将在通过连接器块之后立即与可动插头接触，并且在引脚和插头进一步前进以使引脚进入其最终位置时将保持接触并密封引线管腔与连接器触点电接触。

3. 发明授权

US08518062B2 Devices and methods for forming magnetic anastomoses between vessels 失效
标题翻译：用于在血管之间形成磁性吻合的装置和方法
公开(公告)号：US08518062B2
公开(公告)日：2013-08-27
申请号：US10299582
申请日：2002-11-18
申请人： David H. Cole , Darin C. Gittings , Stephen L. Olson , Dean F. Carson , Michael L. Reo , Keke Lepulu , A. Adam Sharkawy
发明人： David H. Cole , Darin C. Gittings , Stephen L. Olson , Dean F. Carson , Michael L. Reo , Keke Lepulu , A. Adam Sharkawy
IPC分类号： A61B17/08
CPC分类号： A61B17/0643 , A61B17/00491 , A61B17/0057 , A61B17/0469 , A61B17/064 , A61B17/0644 , A61B17/068 , A61B17/11 , A61B2017/00252 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00876 , A61B2017/1107 , A61B2017/1135 , A61B2017/1139 , A61F2/064 , A61F2002/30079 , A61F2210/009 , H01F7/0242
摘要： An anastomosis device has first and second components which each having first and second parts. The first and second components are magnetically attracted to one another. The device forms a throughhole when in use. The first parts of the first and second components are positioned radially outward from the second parts relative to the longitudinal axis with the first parts of the first and second components contacting one another and being magnetically attracted to one another. The second parts of the first and second components also being magnetically attracted to one another and are separated by the vessel walls.
摘要翻译：吻合装置具有第一和第二部件，每个部件具有第一和第二部分。第一和第二组分彼此磁吸引。使用时该装置形成通孔。第一和第二部件的第一部分相对于纵向轴线从第二部分径向向外定位，第一和第二部件的第一部分彼此接触并彼此磁吸引。第一和第二部件的第二部分也被磁吸引并被容器壁隔开。

4. 发明授权

US06979356B1 Capacitor with thermosealed polymeric case for implantable medical device 失效
公开(公告)号：US06979356B1
公开(公告)日：2005-12-27
申请号：US09927567
申请日：2001-08-09
申请人： Dean F. Carson
发明人： Dean F. Carson
IPC分类号： H01G9/00 , H01G9/008 , H01G9/08 , H01G9/12
CPC分类号： H01G9/08 , H01G9/008 , H01G9/12 , Y10T29/417
摘要： An electrolytic capacitor with a polymeric housing in the form of a pocket defining a chamber, with an opening along a selected edge. The opening has opposed sides that are sealed together to provide a seam. A number of conductive layers are positioned within the chamber, and a feed-through conductor element has a first end electrically connected to the layers. An intermediate portion of the feed through passes through the seam, and an external portion extends from the housing. The housing may be vacuum formed high density polyethylene, with the feed-through contained in an elastomeric sleeve having a flattened cross section to be readily received in the seam, and to accommodate thermal expansion differences between the housing and the feedthrough. The device may be manufactured by inserting a stack of layers in the pocket, and thermally welding across the opening of the pocket on a single weld line.

5. 发明授权

US06377856B1 Device and method for implanting medical leads 失效
标题翻译：用于植入医用引线的装置和方法
公开(公告)号：US06377856B1
公开(公告)日：2002-04-23
申请号：US09332535
申请日：1999-06-14
申请人： Dean F. Carson
发明人： Dean F. Carson
IPC分类号： A61N105
CPC分类号： A61N1/056 , A61N2001/0585
摘要： An intravenous cardiac lead having a lumen for delivering a contrast agent as an aid in placement within the coronary sinus or a coronary vein. Also disclosed is a method for advancing such a lead through the right atrium and into the coronary sinus.
摘要翻译：具有用于输送造影剂的管腔的静脉内心脏引导件用于辅助放置在冠状窦或冠状静脉内。还公开了一种使这种铅通过右心房并进入冠状窦的方法。

6. 发明授权

US5931862A Medical lead and method of making and using with sodium sulfosuccinic ester 失效
标题翻译：医用铅和磺基琥珀酸钠的制备和使用方法
公开(公告)号：US5931862A
公开(公告)日：1999-08-03
申请号：US995685
申请日：1997-12-22
申请人： Dean F. Carson
发明人： Dean F. Carson
IPC分类号： A61N1/05 , A61N1/04
CPC分类号： A61N1/056 , A61N1/0563
摘要： A continuous sheath of open-celled porous plastic, preferably ePTFE, is used on the outside of a medical lead, extending along the lead body and the electrodes. Because the plastic is open-celled, when the pores are filled with saline, the lead can deliver electrical energy through the pores in the plastic. Pore size is chosen to discourage tissue ingrowth while allowing for defibrillation energy delivery and electrical signals through it. The porous plastic has a biocompatible wetting agent applied to it to speed the process of filling the pores with saline.
摘要翻译：开放式多孔塑料的连续护套，优选为ePTFE，用于沿引线体和电极延伸的医用引线的外侧。因为塑料是开孔的，当孔中充满盐水时，铅可以通过塑料中的孔传递电能。选择孔径来阻止组织向内生长，同时允许组织向内生长，同时允许除颤能量传递和电信号通过它。多孔塑料具有施加于其上的生物相容润湿剂以加速用盐水填充孔的过程。

7. 发明授权

US5658327A Intracardiac lead having a compliant fixation device 失效
标题翻译：心内线具有顺应性固定装置
公开(公告)号：US5658327A
公开(公告)日：1997-08-19
申请号：US574801
申请日：1995-12-19
申请人： Peter A. Altman , M. Elizabeth Bush , Dean F. Carson
发明人： Peter A. Altman , M. Elizabeth Bush , Dean F. Carson
IPC分类号： A61N1/05
CPC分类号： A61N1/0573
摘要： Intracardiac lead for compliant fixation of a distal end of the lead to cardiac tissue. A fixation helix is disposed at the distal end of the lead. The fixation helix has a first end rigidly attached to the compliant fixation device and a second end that is sharpened to facilitate insertion of the fixation helix into cardiac tissue. The fixation helix can be designed to provide for either electrically active or inactive fixation. Once the lead is implanted in the cardiac tissue, the compliant fixation device, connecting the lead with the fixation helix, reduces the amount of lead movement that is transferred to the patient's tissue at the site of implantation of the fixation helix and reduces those forces from lead movement that could cause dislodgment of the fixation helix. The compliant fixation device thereby decreases the amount of irritation to the cardiac tissue, lessens the possibility of fibrous tissue growth around the area of the fixation helix, decreases the chance of dislodgment of the fixation helix, and reduces the possibility of perforation of the cardiac wall or tamponade of the pericardial sac.
摘要翻译：用于将铅的远端顺利地固定到心脏组织的心内线。固定螺旋设置在引线的远端。固定螺旋具有刚性地连接到顺应性固定装置的第一端和被锐化的便于将固定螺旋插入到心脏组织中的第二端。固定螺旋可以设计成提供电活动或非活动固定。一旦将铅植入心脏组织中，将引线与固定螺旋连接的顺应性固定装置减少了在植入固定螺旋部位时转移到患者组织的引线移动量，并将这些力从导致运动可能导致固定螺旋的移动。顺应性固定装置因此减少对心脏组织的刺激的量，减少了在固定螺旋区域周围的纤维组织生长的可能性，减少了固定螺旋的移动的可能性，并且降低了心脏壁穿孔的可能性或心包囊的填塞。

8. 发明授权

US07431727B2 Magnetic components for use in forming anastomoses, creating ports in vessels and closing openings in tissue 失效
标题翻译：用于形成吻合的磁性部件，在血管中形成端口并封闭组织中的开口
公开(公告)号：US07431727B2
公开(公告)日：2008-10-07
申请号：US10774345
申请日：2004-02-06
申请人： David H. Cole , Samuel T. Crews , Michael L. Reo , Dean F. Carson , Keke J. Lepulu , Darin C. Gittings
发明人： David H. Cole , Samuel T. Crews , Michael L. Reo , Dean F. Carson , Keke J. Lepulu , Darin C. Gittings
IPC分类号： A61B17/08
CPC分类号： A61F2/2493 , A61B17/00491 , A61B17/0057 , A61B17/0469 , A61B17/064 , A61B17/0643 , A61B17/11 , A61B2017/00247 , A61B2017/00252 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00876 , A61B2017/1107 , A61B2017/1132 , A61B2017/1135 , A61B2017/1139 , A61B2018/00392 , A61F2/064 , A61F2/07 , A61F2/94 , A61F2002/30079 , A61F2210/0076 , A61F2210/009 , H01F7/0263 , H01F41/026
摘要： Methods and devices for forming an anastomosis between hollow bodies utilize magnetic force to couple anastomotic securing components and connect the lumens of the hollow bodies. End-to-side, side-to-side and end-to-end anastomoses can be created without using suture or any other type of mechanical fasteners, although such attachment means may be used in practicing some aspects of the invention. The securing components have the ability to produce a magnetic field and may include materials or assemblies. A component may also be used to form a port into the lumen of a vessel, the component being attached to the vessel by mechanical and/or magnetic means. Magnetic components may include means for concentrating the magnetic flux between respective components to increase the attraction force, thereby enhancing the security of the anastomosis. Also, rather than form a port communicating with a lumen of a vessel or other cavity, the components may have an occlusion surface and be used to close an opening in tissue, e.g., an atrial septal defect.
摘要翻译：用于形成中空体之间的吻合的方法和装置利用磁力来联接吻合的固定部件并连接中空体的内腔。可以在不使用缝合线或任何其它类型的机械紧固件的情况下创建端对侧，侧向对侧和端对端吻合，尽管这些附接手段可用于实践本发明的某些方面。固定部件具有产生磁场的能力并且可以包括材料或组件。组件也可用于在容器的内腔中形成端口，该部件通过机械和/或磁性方式附接到容器。磁性部件可以包括用于将磁通集中在各个部件之间以增加吸引力的装置，从而增强吻合的安全性。而且，组件可以具有闭塞表面，并且用于封闭组织中的开口，例如房间隔缺损，而不是形成与容器或其它空腔的内腔连通的端口。

9. 发明授权

US06719768B1 Magnetic components for use in forming anastomoses, creating ports in vessels and closing openings in tissue 失效
标题翻译：用于形成吻合的磁性部件，在血管中形成端口并封闭组织中的开口
公开(公告)号：US06719768B1
公开(公告)日：2004-04-13
申请号：US09638805
申请日：2000-08-12
申请人： David H. Cole , Samuel T. Crews , Michael L. Reo , Dean F. Carson , Keke J. Lepulu , Darin C. Gittings
发明人： David H. Cole , Samuel T. Crews , Michael L. Reo , Dean F. Carson , Keke J. Lepulu , Darin C. Gittings
IPC分类号： A61B1708
CPC分类号： A61F2/2493 , A61B17/00491 , A61B17/0057 , A61B17/0469 , A61B17/064 , A61B17/0643 , A61B17/11 , A61B2017/00247 , A61B2017/00252 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00876 , A61B2017/1107 , A61B2017/1132 , A61B2017/1135 , A61B2017/1139 , A61B2018/00392 , A61F2/064 , A61F2/07 , A61F2/94 , A61F2002/30079 , A61F2210/0076 , A61F2210/009 , H01F7/0263 , H01F41/026
摘要： Methods and devices for forming an anastomosis between hollow bodies utilize magnetic force to couple anastomotic securing components and connect the lumens of the hollow bodies. End-to-side, side-to-side and end-to-end anastomoses can be created without using suture or any other type of mechanical fasteners, although such attachment means may be used in practicing some aspects of the invention. The securing components have the ability to produce a magnetic field and may include materials or assemblies. A component may also be used to form a port into the lumen of a vessel, the component being attached to the vessel by mechanical and/or magnetic means. Magnetic components may include means for concentrating the magnetic flux between respective components to increase the attraction force, thereby enhancing the security of the anastomosis. Also, rather than form a port communicating with a lumen of a vessel or other cavity, the components may have an occlusion surface and be used to close an opening in tissue, e.g., an atrial septal defect.
摘要翻译：用于形成中空体之间的吻合的方法和装置利用磁力来联接吻合的固定部件并连接中空体的内腔。可以在不使用缝合线或任何其它类型的机械紧固件的情况下创建端对侧，侧向对侧和端对端吻合，尽管这些附接手段可用于实践本发明的某些方面。固定部件具有产生磁场的能力并且可以包括材料或组件。组件也可用于在容器的内腔中形成端口，该部件通过机械和/或磁性方式附接到容器。磁性部件可以包括用于将磁通集中在各个部件之间以增加吸引力的装置，从而增强吻合的安全性。而且，组件可以具有闭塞表面，并且用于封闭组织中的开口，例如房间隔缺损，而不是形成与容器或其它空腔的内腔连通的端口。

10. 发明授权

US06635214B2 Manufacturing conduits for use in placing a target vessel in fluid communication with a source of blood 失效
标题翻译：用于放置目标血管与血液源流体连通的制造管道
公开(公告)号：US06635214B2
公开(公告)日：2003-10-21
申请号：US09394119
申请日：1999-09-10
申请人： Alan R. Rapacki , Dean F. Carson , A. Adam Sharkawy
发明人： Alan R. Rapacki , Dean F. Carson , A. Adam Sharkawy
IPC分类号： B29C3902
CPC分类号： A61F2/2493 , A61B2017/00252 , A61F2/064 , B29C41/14 , B29C45/14598 , B29C45/261 , B29C66/857 , B29L2023/007 , B29L2031/7534 , B29C65/00
摘要： Methods and devices for manufacturing a conduit for placing a target vessel in fluid communication with a source of blood, such as a heart chamber containing blood. The conduit includes first and second portion adapted to be placed in fluid communication with a heart chamber and a target vessel. The conduit lies on the exterior of the myocardium between the blood source and the target vessel and delivers blood in multiple directions within the lumen of the target vessel. The conduit, which may be formed of any suitable synthetic vascular graft material, is generally T-shaped with the leg having two free ends disposed in the target vessel, preferably being secured thereto via a suture-free attachment. The conduit comprises vascular graft material and may be manufactured various ways, such as molding a conduit from any suitable biocompatible material or fabricating a conduit from one or more pieces of vascular graft material.
摘要翻译：用于制造用于放置目标血管与血液源（例如含有血液的心室）流体连通的导管的方法和装置。导管包括适于与心脏腔室和靶容器流体连通的第一和第二部分。导管位于血液源和目标血管之间的心肌外部，并在目标血管内腔内的多个方向输送血液。可以由任何合适的合成血管移植材料形成的导管通常是T形的，腿部具有设置在靶容器中的两个自由端，优选通过无缝线的附件固定到其上。导管包括血管移植材料，并且可以以各种方式制造，例如从任何合适的生物相容性材料模制导管或从一个或多个血管移植物材料制造导管。

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