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1. 发明申请

US20120215251A1 CUTTING BALLOON WITH CONNECTOR AND DILATION ELEMENT 有权
标题翻译：切割气球与连接器和放大元件
公开(公告)号：US20120215251A1
公开(公告)日：2012-08-23
申请号：US13462458
申请日：2012-05-02
申请人： David G. Burton , Darin G. Schaeffer , David A. Drewes
发明人： David G. Burton , Darin G. Schaeffer , David A. Drewes
IPC分类号： A61M29/02
CPC分类号： A61B17/320725 , A61B2017/22061 , A61M25/10 , A61M25/1027 , A61M25/1029 , A61M25/1038 , A61M25/104 , A61M29/02 , A61M2025/1086 , B29C49/04 , B29C49/20 , B29C2049/2017 , B29K2067/003 , B29K2077/00 , B29L2031/7543
摘要： A balloon catheter is provided that may be used to dilate hardened regions of a stenosis. The balloon catheter is provided with one or more dilation elements that extend along a surface of a balloon. Each dilation element is connected to an outer surface of the balloon by a connector. The connector is sufficiently sized and designed to undergo stress-induced plastic deformation incurred during blow molding so that a significant portion of each of the dilation elements does not become absorbed into the wall of the final blow molded balloon, thereby maintaining the structural integrity of each of the dilation elements.
摘要翻译：提供了可用于扩张狭窄的硬化区域的气囊导管。球囊导管设置有沿着气球表面延伸的一个或多个扩张元件。每个扩张元件通过连接器连接到气囊的外表面。该连接器具有足够的尺寸和设计，以在吹塑过程中产生应力引起的塑性变形，使得每个膨胀元件的大部分不会被吸收到最终吹塑气球的壁中，从而保持每个膨胀元件的结构完整性的膨胀元素。

2. 发明申请

US20090234283A1 Cutting Balloon With Connector and Dilation Element 有权
标题翻译：切割气球与连接器和扩张元素
公开(公告)号：US20090234283A1
公开(公告)日：2009-09-17
申请号：US12399705
申请日：2009-03-06
申请人： David G. BURTON , Darin G. Schaeffer , David A. Drewes
发明人： David G. BURTON , Darin G. Schaeffer , David A. Drewes
IPC分类号： A61M25/10 , B29C49/00
CPC分类号： A61B17/320725 , A61B2017/22061 , A61M25/10 , A61M25/1027 , A61M25/1029 , A61M25/1038 , A61M25/104 , A61M29/02 , A61M2025/1086 , B29C49/04 , B29C49/20 , B29C2049/2017 , B29K2067/003 , B29K2077/00 , B29L2031/7543
摘要： A balloon catheter is provided that may be used to dilate hardened regions of a stenosis. The balloon catheter is provided with one or more dilation elements that extend along a surface of a balloon. Each dilation element is connected to an outer surface of the balloon by a connector. The connector is sufficiently sized and designed to undergo stress-induced plastic deformation incurred during blow molding so that a significant portion of each of the dilation elements does not become absorbed into the wall of the final blow molded balloon, thereby maintaining the structural integrity of each of the dilation elements.
摘要翻译：提供了可用于扩张狭窄的硬化区域的气囊导管。球囊导管设置有沿着气球表面延伸的一个或多个扩张元件。每个扩张元件通过连接器连接到气囊的外表面。该连接器具有足够的尺寸和设计，以在吹塑过程中产生应力引起的塑性变形，使得每个膨胀元件的大部分不会被吸收到最终吹塑气球的壁中，从而保持每个膨胀元件的结构完整性的膨胀元素。

3. 发明授权

US09604036B2 Cutting balloon with connector and dilation element 有权
公开(公告)号：US09604036B2
公开(公告)日：2017-03-28
申请号：US13462458
申请日：2012-05-02
申请人： David G. Burton , Darin G. Schaeffer , David A. Drewes
发明人： David G. Burton , Darin G. Schaeffer , David A. Drewes
IPC分类号： A61M25/10 , A61B17/3207 , A61B17/22
CPC分类号： A61B17/320725 , A61B2017/22061 , A61M25/10 , A61M25/1027 , A61M25/1029 , A61M25/1038 , A61M25/104 , A61M29/02 , A61M2025/1086 , B29C49/04 , B29C49/20 , B29C2049/2017 , B29K2067/003 , B29K2077/00 , B29L2031/7543
摘要： A balloon catheter is provided that may be used to dilate hardened regions of a stenosis. The balloon catheter is provided with one or more dilation elements that extend along a surface of a balloon. Each dilation element is connected to an outer surface of the balloon by a connector. The connector is sufficiently sized and designed to undergo stress-induced plastic deformation incurred during blow molding so that a significant portion of each of the dilation elements does not become absorbed into the wall of the final blow molded balloon, thereby maintaining the structural integrity of each of the dilation elements.

4. 发明授权

US08192675B2 Cutting balloon with connector and dilation element 有权
标题翻译：切割气球与连接器和膨胀元件
公开(公告)号：US08192675B2
公开(公告)日：2012-06-05
申请号：US12399705
申请日：2009-03-06
申请人： David G. Burton , Darin G. Schaeffer , David A. Drewes
发明人： David G. Burton , Darin G. Schaeffer , David A. Drewes
IPC分类号： B29C49/04
CPC分类号： A61B17/320725 , A61B2017/22061 , A61M25/10 , A61M25/1027 , A61M25/1029 , A61M25/1038 , A61M25/104 , A61M29/02 , A61M2025/1086 , B29C49/04 , B29C49/20 , B29C2049/2017 , B29K2067/003 , B29K2077/00 , B29L2031/7543
摘要： A balloon catheter is provided that may be used to dilate hardened regions of a stenosis. The balloon catheter is provided with one or more dilation elements that extend along a surface of a balloon. Each dilation element is connected to an outer surface of the balloon by a connector. The connector is sufficiently sized and designed to undergo stress-induced plastic deformation incurred during blow molding so that a significant portion of each of the dilation elements does not become absorbed into the wall of the final blow molded balloon, thereby maintaining the structural integrity of each of the dilation elements.
摘要翻译：提供了可用于扩张狭窄的硬化区域的气囊导管。球囊导管设置有沿着气球表面延伸的一个或多个扩张元件。每个扩张元件通过连接器连接到气囊的外表面。该连接器具有足够的尺寸和设计，以在吹塑过程中产生应力引起的塑性变形，使得每个膨胀元件的大部分不会被吸收到最终吹塑气球的壁中，从而保持每个膨胀元件的结构完整性的膨胀元素。

5. 发明申请

US20080132836A1 BALLOON CATHETER HAVING IMPROVED BALLOON FOLDING CAPABILITY 有权
标题翻译：具有改进的气球折叠能力的气球导管
公开(公告)号：US20080132836A1
公开(公告)日：2008-06-05
申请号：US11926767
申请日：2007-10-29
申请人： David G. Burton , David A. Drewes , Eric R. Hennessy , Darin G. Schaeffer
发明人： David G. Burton , David A. Drewes , Eric R. Hennessy , Darin G. Schaeffer
IPC分类号： A61M25/10
CPC分类号： A61M25/10 , A61M25/1038 , A61M2025/1004
摘要： The present invention provides apparatus and methods for facilitating folding of a balloon before, during or after a medical procedure. In a first embodiment, the apparatus generally comprises at least one catheter shaft member, a balloon disposed on a distal region of the catheter shaft member, and at least one folding member disposed along at least a proximal region of the balloon. The folding member may comprise at least one radially-outward projecting member integrally formed with or attached to the balloon, or an internally-formed groove in the balloon, which is adapted to promote twisting of the balloon to reduce the profile of the balloon in the deflated state. Optionally, biasing members may be disposed between the folding member and an adjacent portion of the balloon to promote folding of the balloon in a clockwise or counter-clockwise direction.
摘要翻译：本发明提供了用于在医疗过程之前，期间或之后便于折叠气囊的装置和方法。在第一实施例中，该装置通常包括至少一个导管轴构件，设置在导管轴构件的远侧区域上的气囊，以及沿气囊的至少近侧区域设置的至少一个折叠构件。折叠构件可以包括与球囊一体地形成或附接到球囊上的至少一个径向向外突出的构件，或者球囊中的内部形成的凹槽，其适于促进气球的扭转，以减小球囊的轮廓放气状态可选地，偏压构件可以设置在折叠构件和球囊的相邻部分之间，以促进气囊沿顺时针或逆时针方向的折叠。

6. 发明授权

US07857786B2 Balloon catheter having improved balloon folding capability 有权
标题翻译：球囊导管具有改善的球囊折叠能力
公开(公告)号：US07857786B2
公开(公告)日：2010-12-28
申请号：US11926767
申请日：2007-10-29
申请人： David G. Burton , David A. Drewes, Jr. , Eric R. Hennessy , Darin G. Schaeffer
发明人： David G. Burton , David A. Drewes, Jr. , Eric R. Hennessy , Darin G. Schaeffer
IPC分类号： A61M31/00
CPC分类号： A61M25/10 , A61M25/1038 , A61M2025/1004
摘要： The present invention provides apparatus and methods for facilitating folding of a balloon before, during or after a medical procedure. In a first embodiment, the apparatus generally comprises at least one catheter shaft member, a balloon disposed on a distal region of the catheter shaft member, and at least one folding member disposed along at least a proximal region of the balloon. The folding member may comprise at least one radially-outward projecting member integrally formed with or attached to the balloon, or an internally-formed groove in the balloon, which is adapted to promote twisting of the balloon to reduce the profile of the balloon in the deflated state. Optionally, biasing members may be disposed between the folding member and an adjacent portion of the balloon to promote folding of the balloon in a clockwise or counter-clockwise direction.
摘要翻译：本发明提供了用于在医疗过程之前，期间或之后便于折叠气囊的装置和方法。在第一实施例中，该装置通常包括至少一个导管轴构件，设置在导管轴构件的远侧区域上的气囊，以及沿气囊的至少近侧区域设置的至少一个折叠构件。折叠构件可以包括与球囊一体地形成或附接到球囊上的至少一个径向向外突出的构件，或者球囊中的内部形成的凹槽，其适于促进气球的扭转，以减小球囊的轮廓放气状态可选地，偏压构件可以设置在折叠构件和球囊的相邻部分之间，以促进气囊沿顺时针或逆时针方向的折叠。

7. 发明授权

US07731685B2 Coated medical device 有权
标题翻译：涂层医疗器械
公开(公告)号：US07731685B2
公开(公告)日：2010-06-08
申请号：US11234702
申请日：2005-09-23
申请人： Anthony O. Ragheb , Brian L. Bates , Scott E. Boatman , David G. Burton , Michael C. Hoffa , Darin G. Schaeffer , Jason S. Sturgeon
发明人： Anthony O. Ragheb , Brian L. Bates , Scott E. Boatman , David G. Burton , Michael C. Hoffa , Darin G. Schaeffer , Jason S. Sturgeon
IPC分类号： A61M31/00
CPC分类号： A61M25/10 , A61F2/82 , A61F2/844 , A61F2/86 , A61F2/958 , A61F2210/0014 , A61F2210/0076 , A61F2240/001 , A61F2250/0025 , A61F2250/0026 , A61F2250/0067 , A61F2250/0081 , A61F2250/0098 , A61F2310/00011 , A61L27/54 , A61L29/08 , A61L29/085 , A61L29/16 , A61L29/18 , A61L31/14 , A61L31/16 , A61L2300/416 , A61L2300/606 , A61L2400/18 , A61L2420/02 , A61L2420/06 , A61M25/1029 , A61M25/104 , A61M2025/1031 , A61M2025/105 , A61M2250/00
摘要： A coated medical device adapted for introduction into a passage or vessel of a patient is provided. The medical device is preferably an implantable balloon with a bioactive deposited or within the balloon. The balloon can further include a hydrophilic material positioned between the balloon and a bioactive material posited on the balloon.
摘要翻译：提供适于引入患者的通道或容器中的涂覆医疗装置。医疗装置优选地是具有生物活性沉积的或在球囊内的可植入气球。球囊可以进一步包括位于球囊和放置在球囊上的生物活性物质之间的亲水材料。

8. 发明授权

US10532190B2 Coated medical device 有权
公开(公告)号：US10532190B2
公开(公告)日：2020-01-14
申请号：US12892177
申请日：2010-09-28
申请人： Brian L. Bates , Scott E. Boatman , David G. Burton , Michael C. Hoffa , Darin G. Schaeffer , Jason S. Sturgeon , Anthony O. Ragheb
发明人： Brian L. Bates , Scott E. Boatman , David G. Burton , Michael C. Hoffa , Darin G. Schaeffer , Jason S. Sturgeon , Anthony O. Ragheb
IPC分类号： A61M31/00 , A61M25/10 , A61F2/82 , A61L27/54 , A61L31/16 , A61L29/16 , A61F2/844 , A61F2/958 , A61L29/08 , A61L29/18 , A61L31/14 , A61F2/86
摘要： A coated medical device (10) including a structure (12) adapted for introduction into a passage or vessel of a patient. The structure is formed of preferably a non-porous base material (14) having a bioactive material layer (18) disposed thereon. The medical device is preferably an implantable stent or balloon (26) of which the bioactive material layer is deposited thereon. The stent can be positioned around the balloon and another layer of the bioactive material posited over the entire structure and extending beyond the ends of the positioned stent. The ends of the balloon extend beyond the ends of the stent and include the bioactive material thereon for delivering the bioactive material to the cells of a vessel wall coming in contact therewith. The balloon further includes a layer of hydrophilic material (58) positioned between the base and bioactive material layers of the balloon.

9. 发明申请

US20110015725A1 COATED MEDICAL DEVICE 审中-公开
标题翻译：涂层医疗器械
公开(公告)号：US20110015725A1
公开(公告)日：2011-01-20
申请号：US12892177
申请日：2010-09-28
申请人： Brian L. Bates , Scott E. Boatman , David G. Burton , Michael C. Hoffa , Darin G. Schaeffer , Jason S. Sturgeon , Anthony O. Ragheb
发明人： Brian L. Bates , Scott E. Boatman , David G. Burton , Michael C. Hoffa , Darin G. Schaeffer , Jason S. Sturgeon , Anthony O. Ragheb
IPC分类号： A61F2/82
摘要： A coated medical device (10) including a structure (12) adapted for introduction into a passage or vessel of a patient. The structure is formed of preferably a non-porous base material (14) having a bioactive material layer (18) disposed thereon. The medical device is preferably an implantable stent or balloon (26) of which the bioactive material layer is deposited thereon. The stent can be positioned around the balloon and another layer of the bioactive material posited over the entire structure and extending beyond the ends of the positioned stent. The ends of the balloon extend beyond the ends of the stent and include the bioactive material thereon for delivering the bioactive material to the cells of a vessel wall coming in contact therewith. The balloon further includes a layer of hydrophilic material (58) positioned between the base and bioactive material layers of the balloon.
摘要翻译：一种涂覆的医疗装置（10），包括适于引入患者的通道或容器中的结构（12）。该结构优选由其上设置有生物活性材料层（18）的无孔基材（14）形成。该医疗装置优选为其上沉积有生物活性物质层的可植入支架或球囊（26）。支架可以围绕气囊定位，另一层生物活性材料放置在整个结构上并延伸超过定位的支架的端部。气囊的端部延伸超过支架的端部并且包括其上的生物活性材料，用于将生物活性材料输送到与其接触的血管壁的细胞。气囊还包括位于气囊的基部和生物活性材料层之间的一层亲水材料（58）。

10. 发明申请

US20080086084A1 BALLOON CATHETER 有权
标题翻译：气球导管
公开(公告)号：US20080086084A1
公开(公告)日：2008-04-10
申请号：US11858658
申请日：2007-09-20
申请人： Darin G. Schaeffer , David G. Burton
发明人： Darin G. Schaeffer , David G. Burton
IPC分类号： A61M29/02
CPC分类号： A61M25/1029 , A61M25/1034 , A61M25/104 , A61M2025/1031 , A61M2025/1063
摘要： An balloon catheter is provided with an improved neck portion. The neck portion of the balloon is used to attach the end of the balloon to a catheter. Before attaching the balloon to the catheter, the neck portion is lengthened and thinned out to make the neck portion more flexible. Heat shrink tubing may be used to apply pressure to the neck portion to force the material of the neck portion to flow along a mandrel inserted into the neck portion.
摘要翻译：气囊导管设置有改进的颈部。气囊的颈部用于将气囊的端部附接到导管。在将气囊附接到导管之前，颈部被延长并变薄，使得颈部更柔韧。热收缩管可用于向颈部施加压力，以迫使颈部的材料沿着插入颈部的心轴流动。

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