专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2021239932A1 MEDICAL IMPLANT FOR CARTILAGE REPLACEMENT AND METHOD OF MAKING SUCH IMPLANT 审中-公开
公开(公告)号：WO2021239932A1
公开(公告)日：2021-12-02
申请号：PCT/EP2021/064318
申请日：2021-05-28
申请人： DSM IP ASSETS B.V. , MAASTRICHT UNIVERSITAIR MEDISCH CENTRUM+ , TECHNISCHE UNIVERSITEIT EINDHOVEN , UNIVERSITY MAASTRICHT
发明人： OEVERING, Hendrik , GELISSEN, Franciscus, Wilhelmus, Maria , THIES, Jens, Christoph , EMANS, Pieter , ROTH, Alex, Kristian , VAN DONKELAAR, Corrinus, Cornelis , ASIK, Emin, Erkan
IPC分类号： A61F2/30 , A61L27/18 , A61L27/44
摘要： Present invention relates to an orthopedic implant having a bone anchoring part comprising a polymer composition comprising a biostable thermoplastic polyurethane (TPU) and 15-70 mass% of inorganic particles comprising zirconia. It was found that this relatively rigid anchoring part allows inserting an implant into a pre-drilled bone hole to form a firm and durable connection to bone, which may be visualized with for example X-ray or MRI methods. The thermoplastic polyurethane composition shows favorable properties, and offers freedom in design and dimensioning of the implant, and in making the implant with common techniques like injection molding. Especially if the implant comprises a cartilage replacing part made from a resilient thermoplastic material compatible with the polyurethane-zirconia composition, like a more flexible TPU composition, the implant may be made with a 2-component injection molding technique. In other aspects, the invention relates to a method of making said orthopedic implant comprising a bone anchoring part with a multi-component injection molding process. The invention further relates to a surgical kit of parts comprising orthopedic implants of the invention, and to the use of an implant or a surgical kit of the invention in orthopedic surgery.

3. 发明申请

WO2021239931A1 POLYMER COMPOSITION AND METHOD OF MAKING A MEDICAL IMPLANT 审中-公开
公开(公告)号：WO2021239931A1
公开(公告)日：2021-12-02
申请号：PCT/EP2021/064317
申请日：2021-05-28
申请人： MAASTRICHT UNIVERSITAIR MEDISCH CENTRUM+ , UNIVERSITY MAASTRICHT , DSM IP ASSETS B.V.
发明人： OEVERING, Hendrik , GELISSEN, Franciscus, Wilhelmus, Maria , THIES, Jens, Christoph , EMANS, Pieter , ROTH, Alex, Kristian
IPC分类号： C08G18/32 , C08G18/44 , C08G18/76 , C08L75/06
摘要： The invention concerns a polymer composition for making a bone anchoring part of an orthopedic implant for use in repair of damaged cartilage tissue, comprising a biostable thermoplastic polyurethane and 15-70 mass% of micron-sized inorganic particles comprising a biocompatible transition metal compound. It was found that the relatively rigid TPU composition comprising said inorganic particles allows making an anchoring part that can be inserted or press-fitted into a pre-drilled bone hole to form a firm and durable connection to bone tissue, and which may be visualized with for example X-ray or MRI methods. The polymer composition shows favorable properties and enables freedom in designing and making the implant with common techniques like injection molding. In other aspects, the invention relates to methods of making said polymer composition, and to using the polymer composition in making an orthopedic implant comprising a bone anchoring part, like in forming the implant with a multi-component injection molding process comprising a step of molding the bone anchoring part from the polymer composition.

4. 发明公开

EP4157913A1 POLYMER COMPOSITION AND METHOD OF MAKING A MEDICAL IMPLANT 有权转让
公开(公告)号：EP4157913A1
公开(公告)日：2023-04-05
申请号：EP21729498.2
申请日：2021-05-28
申请人： Maastricht Universitair Medisch Centrum+ , Maastricht University , DSM IP Assets B.V.
发明人： OEVERING, Hendrik , GELISSEN, Franciscus Wilhelmus Maria , THIES, Jens Christoph , EMANS, Pieter , ROTH, Alex Kristian
IPC分类号： C08G18/32 , C08G18/44 , C08G18/76 , C08L75/06

5. 发明申请

WO2007006458A1 PROCESS FOR THE CONTINUOUS PRODUCTION OF HYDROXYLAMMONIUM 审中-公开
标题翻译：连续生产羟基亚胺的方法
公开(公告)号：WO2007006458A1
公开(公告)日：2007-01-18
申请号：PCT/EP2006/006507
申请日：2006-07-04
申请人： DSM IP ASSETS B.V. , OEVERING, Hendrik , POORTER, Olaf
发明人： OEVERING, Hendrik , POORTER, Olaf
IPC分类号： C01B21/14 , C07C249/04 , C07C239/00
CPC分类号： C07C249/08 , B01J23/624 , C01B21/1418 , C07C2601/14 , C07C251/44
摘要： Process and equipment for the continuous production of hydroxyl ammonium by reduction of nitrate ions or nitrogen oxides with hydrogen in the presence of a catalyst whereby the hydroxyl ammonium is produced in 2 or more parallel placed hydroxyl ammonium production units which process is optionally part of a process for the production of cyclohexanone oxime in which an inorganic process liquid is cycled from a hydroxyl ammonium synthesis zone (A) to a cyclohexanone oxime synthesis zone (B) and back to the hydroxyl ammonium synthesis zone for example through an extraction zone (C) and a nitric acid production zone (D), in which hydroxyl ammonium synthesis zone hydroxyl ammonium is formed by reduction of nitrate ions or nitrogen oxides with hydrogen in the presence of a catalyst, and in which cyclohexanone oxime synthesis zone hydroxyl ammonium is reacted with cyclohexanone to form cyclohexanone oxime.
摘要翻译：在催化剂存在下通过还原硝酸根离子或氮氧化物连续生产羟基铵的方法和设备，由此在2个或更多个平行放置的羟基铵生产单元中产生羟基铵，该过程任选地是一个过程的一部分用于生产其中无机工艺液体从羟基铵合成区（A）循环到环己酮肟合成区（B）并回到羟基铵合成区的环己酮肟，例如通过萃取区（C）和硝酸生产区（D），其中通过在催化剂存在下用氢还原硝酸根离子或氮氧化物而形成羟基铵合成区羟基铵，并且其中环己酮肟合成区羟基铵与环己酮反应生成形成环己酮肟。

6. 发明申请

WO2019053287A1 A METHOD FOR OBTAINING A STABLE LIGNIN: POLAR ORGANIC SOLVENT COMPOSITION VIA MILD SOLVOLYTIC MODIFICATIONS 审中-公开
公开(公告)号：WO2019053287A1
公开(公告)日：2019-03-21
申请号：PCT/EP2018/075225
申请日：2018-09-18
申请人： TECHNISCHE UNIVERSITEIT EINDHOVEN
发明人： KOURIS, Panagiotis , BOOT, Michael Dirk , HENSEN, Emiel Jan Maria , OEVERING, Hendrik
IPC分类号： C10L1/02
摘要： The present invention relates to a process the production of a crude liquid lignin oil (CLO), said process comprises the steps of providing a lignin-rich solid feedstock and subjecting the lignin-rich solid feedstock to a treatment in a polar organic solvent in the absence of an effective amount of added reaction promoter, such as a heterogeneous and/or homogeneous catalyst and/or hydrogen, and providing a lignin composition, said treatment comprises a step of contacting said lignin-rich solid feedstock with a polar organic solvent under operating conditions of an operating temperature up to 210 °C, an operating pressure lower than 50 bar and a residence time up to 240 minutes, wherein the ratio (w/v) of lignin (in lignin- rich feedstock) to polar organic solvent ranges between 1:1.5 and 1:15, or between 1:2 and 1:10 or between 1:2 and 1:5.

7. 发明申请

WO2010040774A2 DESTRUCTION OF AMMONIUM IONS 审中-公开
标题翻译：破坏氨离子
公开(公告)号：WO2010040774A2
公开(公告)日：2010-04-15
申请号：PCT/EP2009/063023
申请日：2009-10-07
申请人： DSM IP ASSETS B.V. , OEVERING, Hendrik , GUIT, Rudolf Philippus Maria , LOPEZ CRUZ, Carlos , RIESTHUIS, Theodorus Friederich Maria
发明人： OEVERING, Hendrik , GUIT, Rudolf Philippus Maria , LOPEZ CRUZ, Carlos , RIESTHUIS, Theodorus Friederich Maria
IPC分类号： C01B21/02 , C01B21/14 , C07C249/08
CPC分类号： C01B21/02 , C01B21/1418
摘要： The invention relates to a process for converting ammonium formed in a hydroxylamine phosphate oxime process into molecular nitrogen in an ammonium destruction zone, comprising - preparing a vapour stream comprising nitrogen oxide from ammonia, in an ammonia combustion zone; - bringing into contact by feeding to the ammonium destruction zone, individually and/or as pre-mixed combinations, at least part of said vapour stream, and a first liquid stream, comprising ammonium formed in the hydroxylamine phosphate oxime process, and a second liquid stream, comprising at least one acid selected from nitric acid and nitrous acid in a total nitric+nitrous acid concentration of at least 30 wt. %, thereby forming in the ammonium destruction zone a fluid mixture; and - reacting ammonium ions in the fluid mixture with nitrogen oxide under formation of molecular nitrogen, in the ammonium destruction zone. The invention further relates to an installation for converting ammonium formed in a hydroxylamine phosphate oxime process.
摘要翻译：本发明涉及将铵磷酸酯肟工艺中形成的铵转化成铵破坏区中的分子氮的方法，包括：在氨燃烧区中由氨制备包含氮氧化物的蒸气流; - 通过单独地和/或作为预混合组合，至少部分所述蒸汽流进料至铵破坏区和包含在磷酸羟胺肟方法中形成的铵的第一液体流和第二液体流，包含至少一种选自硝酸和亚硝酸的酸，其总硝酸+亚硝酸浓度为至少30重量％。％，从而在铵破坏区中形成流体混合物; 并且在铵破坏区域中使铵离子与氮氧化物在分子氮形成时在流体混合物中反应。本发明还涉及一种用于转化在磷酸羟胺肟工艺中形成的铵的装置。

8. 发明申请

WO2004067497A1 PROCESS FOR TREATING AN ORGANIC SOLUTION COMPRISING CYCLOHEXANONE OXIME, CYCLOHEXANONE, AND AN ORGANIC SOLVENT 审中-公开
标题翻译：用于处理包含环己酮氧化物，环己酮和有机溶剂的有机溶液的方法
公开(公告)号：WO2004067497A1
公开(公告)日：2004-08-12
申请号：PCT/NL2004/000063
申请日：2004-01-28
申请人： DSM IP ASSETS B.V. , OEVERING, Hendrik , BENNEKER, Arno, Herald , BROUWERS, Johannes, Antonius, Leonardus
发明人： OEVERING, Hendrik , BENNEKER, Arno, Herald , BROUWERS, Johannes, Antonius, Leonardus
IPC分类号： C07C249/14
CPC分类号： C07C249/14 , C07C2601/14 , C07C251/44
摘要： The invention relates to a process for treating an organic solution comprising cyclohexanone oxime, cyclohexanone and an organic solvent, said process comprising distilling the organic solution such as to obtain (i) a first product comprising organic solvent, (ii) a second product comprising cyclohexanone and (iii) a third product comprising cyclohexanone oxime; and feeding the second product to a cyclohexanone oxime synthesis zone in which hydroxylammonium is reacted with cyclohexanone to form cyclohexanone oxime.
摘要翻译：本发明涉及一种处理包含环己酮肟，环己酮和有机溶剂的有机溶液的方法，所述方法包括蒸馏有机溶液，以获得（i）包含有机溶剂的第一产物，（ii）包含环己酮的第二产物和（iii）包含环己酮肟的第三产物; 并将第二产物进料到环己酮肟合成区，其中羟基铵与环己酮反应形成环己酮肟。

9. 发明申请

WO2004052780A1 PROCESS FOR MIXING AN ACIDIC AQUEOUS SOLUTION COMPRISING HYDROXYLAMMONIUM AND PHOSPHATE WITH NITRIC ACID 审中-公开
标题翻译：混合含有羟基亚氨酸和磷酸酯的酸性水溶液与硝酸的方法
公开(公告)号：WO2004052780A1
公开(公告)日：2004-06-24
申请号：PCT/NL2003/000877
申请日：2003-12-10
申请人： DSM IP ASSETS B.V. , BENNEKER, Arno, Herald , OEVERING, Hendrik
发明人： BENNEKER, Arno, Herald , OEVERING, Hendrik
IPC分类号： C01B21/14
CPC分类号： C07C249/08 , C01B21/1418
摘要： The invention relates to a process for mixing a first acidic aqueous solution comprising hydroxylammonium and phosphate with a second acidic aqueous solution comprising nitric acid at a temperature between 20 and 80 °C resulting in a third acidic aqueous solution comprising hydroxylammonium, phosphate and nitric acid, wherein in the third acidic aqueous solution the total acid concentration minus the phosphate concentration is lower than 0.523 * ln([hydroxylammonium]/1.25) + 422/(T + 81) whereby [hydroxylammonium] is the concentration of hydroxylammonium in the third acidic aqueous solution, T is the temperature of the third acidic aqueous solution expressed in °C and all concentrations are expressed in mol/l.
摘要翻译：本发明涉及一种将包含羟基铵和磷酸盐的第一酸性水溶液与包含硝酸的第二酸性水溶液在20至80℃之间混合的方法，得到包含羟基铵，磷酸盐和硝酸的第三酸性水溶液，其中在第三酸性水溶液中，总酸浓度减去磷酸盐浓度低于0.523 * ln（[羟基铵] /1.25）+ 422 /（T + 81），由此[羟基铵]是第三酸性水溶液中羟基铵的浓度溶液，T是以℃表示的第三酸性水溶液的温度，所有浓度以mol / l表示。

10. 发明申请

WO2013053377A1 HIGH TEMPERATURE LACTAM NEUTRALISATION 审中-公开
标题翻译：高温乳酸中和
公开(公告)号：WO2013053377A1
公开(公告)日：2013-04-18
申请号：PCT/EP2011/067650
申请日：2011-10-10
申请人： DSM IP ASSETS B.V. , OEVERING, Hendrik , GUIT, Rudolf Philippus Maria , BAUR, Henricus Anna Christiaan
发明人： OEVERING, Hendrik , GUIT, Rudolf Philippus Maria , BAUR, Henricus Anna Christiaan
IPC分类号： C07D201/04 , C07D201/16 , C07D223/10
CPC分类号： C07D201/16 , C07D201/04 , C07D223/10
摘要： The invention relates to a method for preparing a lactam in a continuous process, comprising forming the lactam and ammonium sulphate by contacting a lactam sulphate contained in an acidic liquid with ammonia, during which forming of lactam heat of reaction is generated, which heat is partially or fully recovered, wherein ammonia is brought into contact with the acidic liquid as part of a liquid aqueous ammonia solution, and wherein the contacting takes place at a temperature of at least 120 °C, and wherein the average residence time at a temperature of at least 120 °C is at most 15 minutes, and wherein the ammonium sulphate remains dissolved in a liquid phase during said residence time.
摘要翻译：本发明涉及一种在连续方法中制备内酰胺的方法，包括通过使酸性液体中含有的内酰胺硫酸与氨接触形成内酰胺和硫酸铵，在此期间产生反应的内酰胺热量，该热量部分地或完全回收，其中氨与液体氨水溶液的一部分与酸性液体接触，并且其中接触在至少120℃的温度下进行，并且其中在温度为至少120℃至多为15分钟，其中硫酸铵在所述停留时间期间保持溶于液相。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式