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    • 1. 发明申请
    • Method and system for analysis of cancer biomarkers using proteome image mining
    • 使用蛋白质组图像挖掘分析癌症生物标志物的方法和系统
    • US20070072250A1
    • 2007-03-29
    • US10510937
    • 2002-12-24
    • Chul-Woo KimYoung-Mee ParkJong-Sou ParkSung-Do ChiSyng-Yup OhnSoo-Chan Hwang
    • Chul-Woo KimYoung-Mee ParkJong-Sou ParkSung-Do ChiSyng-Yup OhnSoo-Chan Hwang
    • G01N33/574G06F19/00
    • G01N33/574G16B20/00G16B40/00
    • The present invention provide a system and a method for detection of cancer, by producing a serum proteome standard by an image mining technique, and provide cancer-specific biomarkers. Disclosed is a method of analyzing cancer, comprising the steps of transforming serum proteomes from normal individuals and individuals having cancer into two-dimensional images, and constructing a database consisting of the proteome standard by an image mining technique; inputting a serum proteome from a subject of interest, transforming the serum proteome into a image and comparing the structure of the serum proteome pattern of the subject with the proteome standard and determining whether the serum proteome of the subject is normal or abnormal. The system and method for cancer analysis facilitates detection of cancer by constructing a database from a plurality of serum proteome using an image technique and comparing serum proteome of a subject with a proteome standard.
    • 本发明提供一种通过图像挖掘技术生产血清蛋白质组学标准并提供癌症特异性生物标志物来检测癌症的系统和方法。 本发明公开了一种分析癌症的方法,其特征在于,包括将具有癌症的正常个体和个体的血清蛋白质组转化为二维图像,通过图像挖掘技术构建由蛋白质组学标准组成的数据库的步骤; 从感兴趣的受试者输入血清蛋白质组,将血清蛋白质组转化成图像,并比较受试者的血清蛋白质组图案与蛋白质组标准的结构,并确定受试者的血清蛋白质组是否正常或异常。 用于癌症分析的系统和方法通过使用图像技术从多个血清蛋白质组构建数据库并且将对象的血清蛋白质组与蛋白质组标准进行比较来促进癌症的检测。
    • 5. 发明申请
    • Frequency Multiplier
    • 频率乘数
    • US20090189652A1
    • 2009-07-30
    • US11659023
    • 2005-07-27
    • Chul-Woo KimJin-Han KimSeok-Ryung YoonYoung-Ho KwakSeok-Soo Yoon
    • Chul-Woo KimJin-Han KimSeok-Ryung YoonYoung-Ho KwakSeok-Soo Yoon
    • H03B19/00
    • G06F7/68
    • A frequency multiplier is disclosed. A plurality of voltage regulators each regulate levels of voltages at first and second common nodes in response to a corresponding one of input signals from a voltage-controlled delay line. An input buffer charges the first node or discharges the second node in response to a feedback signal. An output buffer regulates a level of a voltage at an output node and outputs a frequency-multiplied clock signal and the feedback signal corresponding to the voltage level of the output node. A discharge circuit discharges the first node before a rising edge of each of the input signals from the voltage-controlled delay line is inputted. A charge circuit charges the second node before the rising edge of each of the input signals from the voltage-controlled delay line is inputted.
    • 公开了一种倍频器。 多个电压调节器响应于来自电压控制延迟线的输入信号中的相应一个,调节第一和第二公共节点处的电压电平。 输入缓冲器对第一节点进行充电或响应于反馈信号对第二节点进行放电。 输出缓冲器调节输出节点处的电压电平,并输出倍频时钟信号和对应于输出节点电压电平的反馈信号。 在输入来自压控延迟线的每个输入信号的上升沿之前,放电电路对第一节点放电。 在输入来自压控延迟线的每个输入信号的上升沿之前,充电电路对第二节点充电。
    • 8. 发明授权
    • Fe-based bulk amorphous alloy compositions containing more than 5 elements and composites containing the amorphous phase
    • 含有超过5种元素的Fe基块状非晶合金组合物和含有非晶相的复合材料
    • US07815753B2
    • 2010-10-19
    • US11719871
    • 2005-08-11
    • Seong-Hoon YiHong-Xiang LiMyung-Il HeoJong-Chul YiDong-Jin YuSang-Hum KwonChul-Woo KimJong-Won KimIn-Seok Hwang
    • Seong-Hoon YiHong-Xiang LiMyung-Il HeoJong-Chul YiDong-Jin YuSang-Hum KwonChul-Woo KimJong-Won KimIn-Seok Hwang
    • C22C45/02
    • C22C45/02
    • Disclosed is a Fe-based bulk amorphous alloy composition which forms a bulk amorphous substance due to its excellent amorphous formability when it is cooled to a temperature lower than its glass transition temperature from the liquid state at a relatively low cooling rate of 1000 K/s or less, has high warm processability in a low temperature range owing to its supercooled liquid region of 20K or higher and has excellent fluidity in the liquid state and thereby good castability. The Fe-based multi-element bulk amorphous alloy composition is represented by a formula of FeαCβSiγBxPyMa, in which M is at least one element selected from Ti(titanium), Cr(chromium), Mo(molybdenum), Nb(niobium), Zr(Zirconium), Ta(tantalum), W(tungsten) and V(vanadium), α, β, γ, x, y, and a each represent atomic % of iron(Fe), Carbon(C), silicon(Si), boron(B), phosphorus(P) and the selected metal element, in which α is 100-(β+γ+x+y+a) atomic %, β is 6 atomic % or more and 13 atomic % or less, γ is 1 atomic % or more and 5 atomic % or less, x is 4.5 atomic % or more and 9.5 atomic % or less, y is 3 atomic % or more and 10 atomic % or less and a is 0.1 atomic % or more and 6 atomic % or less.
    • 公开了一种Fe基块状非晶态合金组合物,由于其以非常低的冷却速度1000K / s从液态冷却到比其玻璃化转变温度低的温度时,由于其非晶形成性优异而形成块状非晶态物质 或更低,由于其过冷液体区域为20K以上,在低温范围内具有高温加工性,并且在液态下具有优异的流动性,从而具有良好的浇铸性。 Fe基多元素块状非晶合金组合物由FeαCbBiSiYBxPyMa的式表示,其中M为选自Ti(钛),Cr(铬),Mo(钼),Nb(铌) ,Zr(锆),Ta(钽),W(钨)和V(钒),α,bgr,γ,x,y和a分别表示铁(Fe),碳(C) (Si),硼(B),磷(P)和选择的金属元素,其中α为100 - (&bgr。+γ+ x + y + a)原子%,bgr; 为6原子%以上且13原子%以下,γ为1原子%以上且5原子%以下,x为4.5原子%以上且9.5原子%以下,y为3原子%以上10 原子%以下,a为0.1原子%以上且6原子%以下。