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1. 发明申请

US20070072250A1 Method and system for analysis of cancer biomarkers using proteome image mining 审中-公开
标题翻译：使用蛋白质组图像挖掘分析癌症生物标志物的方法和系统
公开(公告)号：US20070072250A1
公开(公告)日：2007-03-29
申请号：US10510937
申请日：2002-12-24
申请人： Chul-Woo Kim , Young-Mee Park , Jong-Sou Park , Sung-Do Chi , Syng-Yup Ohn , Soo-Chan Hwang
发明人： Chul-Woo Kim , Young-Mee Park , Jong-Sou Park , Sung-Do Chi , Syng-Yup Ohn , Soo-Chan Hwang
IPC分类号： G01N33/574 , G06F19/00
CPC分类号： G01N33/574 , G16B20/00 , G16B40/00
摘要： The present invention provide a system and a method for detection of cancer, by producing a serum proteome standard by an image mining technique, and provide cancer-specific biomarkers. Disclosed is a method of analyzing cancer, comprising the steps of transforming serum proteomes from normal individuals and individuals having cancer into two-dimensional images, and constructing a database consisting of the proteome standard by an image mining technique; inputting a serum proteome from a subject of interest, transforming the serum proteome into a image and comparing the structure of the serum proteome pattern of the subject with the proteome standard and determining whether the serum proteome of the subject is normal or abnormal. The system and method for cancer analysis facilitates detection of cancer by constructing a database from a plurality of serum proteome using an image technique and comparing serum proteome of a subject with a proteome standard.
摘要翻译：本发明提供一种通过图像挖掘技术生产血清蛋白质组学标准并提供癌症特异性生物标志物来检测癌症的系统和方法。本发明公开了一种分析癌症的方法，其特征在于，包括将具有癌症的正常个体和个体的血清蛋白质组转化为二维图像，通过图像挖掘技术构建由蛋白质组学标准组成的数据库的步骤; 从感兴趣的受试者输入血清蛋白质组，将血清蛋白质组转化成图像，并比较受试者的血清蛋白质组图案与蛋白质组标准的结构，并确定受试者的血清蛋白质组是否正常或异常。用于癌症分析的系统和方法通过使用图像技术从多个血清蛋白质组构建数据库并且将对象的血清蛋白质组与蛋白质组标准进行比较来促进癌症的检测。

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