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1. 发明申请

US20060113207A1 Heart valve storage and shipping retainer 有权
标题翻译：心脏瓣膜储存和运输保持器
公开(公告)号：US20060113207A1
公开(公告)日：2006-06-01
申请号：US11254510
申请日：2005-10-20
申请人： Timothy Ryan , Cathy Bergin
发明人： Timothy Ryan , Cathy Bergin
IPC分类号： A61B19/02 , A61F2/24
CPC分类号： A61F2/0095 , A61F2/24
摘要： This invention relates to a system and apparatus for retaining a prosthetic valve in a valve pocket suspended in a sealed container to protect from damage and contamination during shipment, handling and storage. The apparatus is an easy to open container having remote fill ports for adding a sterile liquid after enclosing the valve inside. A tamper evident seal is provided having a novel configuration to detect prior opening of the container. The apparatus includes an assembly having a shelf that is provided in a variety of configurations. The shelf has a mitral valve configuration and an aortic valve configuration. The shelf is selected based on the valve configurations and size. The system is easily assembled having a single variable component to adapt to a particular prosthetic valve to be stored. The present invention provides an apparatus for eliminating the need for direct attachment of the valve serial tag to the valve.
摘要翻译：本发明涉及一种用于将假体阀保持在悬挂在密封容器中的阀口袋中的系统和装置，以防止运输，处理和储存期间的损坏和污染。该装置是容易打开的容器，其具有用于在将阀封闭后添加无菌液体的远程填充口。提供了具有新颖结构以检测容器的先前打开的防拆封密封件。该装置包括具有以各种构造设置的搁架的组件。架子具有二尖瓣构造和主动脉瓣构造。根据阀门配置和尺寸选择货架。该系统容易组装具有单个可变部件以适应要存储的特定人造瓣膜。本发明提供了一种用于消除将阀串行标签直接附接到阀门的需要的装置。

2. 发明申请

US20060241743A1 Valve holder 有权
标题翻译：阀座
公开(公告)号：US20060241743A1
公开(公告)日：2006-10-26
申请号：US11357224
申请日：2006-02-17
申请人： Cathy Bergin , Timothy Ryan
发明人： Cathy Bergin , Timothy Ryan
IPC分类号： A61F2/24
CPC分类号： A61F2/2427 , A61F2/2409 , A61F2/2412 , A61F2250/0097
摘要： The present invention is an improved apparatus for holding and maneuvering a valve during preparation and attachment to patient. The present invention is particularly useful for increased visibility of the prosthetic valve and the sewing ring to prevent suture entanglement. The present invention is used most effectively with mitral valves having commissure posts on the outflow side of the valve structure but may be used with other valve configurations. The present invention spaces the handle attachment from the valve for improved visibility of the sewing ring and the outlet end of the valve during attachment. The present invention is adapted to safely bend the commissure posts inward at the tips while preventing crashing the commissure posts into each other causing damage. The new holder prevents suture remnants left in a patient by a designed break point for the holder suture. The present invention reduces the release force needed to remove the holder and unthread the holder sutures by an improved design and method of attachment to the prosthetic valve. The improved holder provides a kink free holder suture path to reduce suture entanglement and prevent damage to the implanted valve during holder removal by reducing the release force needed to remove the holder sutures by up to 30%.
摘要翻译：本发明是一种改进的装置，用于在准备和附接到患者期间保持和操纵阀。本发明特别可用于增加人造瓣膜和缝合环的可见度以防止缝合线缠结。本发明最有效地用于具有在阀结构的流出侧上的合缝的二尖瓣，但是可以与其他阀构造一起使用。本发明将手柄附件从阀处置于空间，以便在连接期间提高缝纫环的可视性和阀的出口端。本发明适用于将接合柱在尖端处向内安全地弯曲，同时防止将接合柱彼此碰撞造成损坏。新的支架通过设计的断裂点防止缝合残留物留在患者身上，用于支架缝线。本发明通过改进的连接到人工瓣膜的设计和方法来减小移除保持器所需的释放力并且使得保持器缝合线无螺纹。改进的保持器提供了无扭结的缝合线路径，以减少缝合线缠结，并通过减少将保持器缝合线移除高达30％所需的释放力，防止在保持器移除过程中损伤植入的瓣膜。

3. 发明申请

US20150088183A1 SURGICAL TOOL MONITORING SYSTEM AND METHODS OF USE 有权
标题翻译：手术工具监测系统及使用方法
公开(公告)号：US20150088183A1
公开(公告)日：2015-03-26
申请号：US14496704
申请日：2014-09-25
申请人： Jeffrey Vipperman , Carl Snyderman , Timothy Ryan , Paul Johnson
发明人： Jeffrey Vipperman , Carl Snyderman , Timothy Ryan , Paul Johnson
IPC分类号： A61B17/16 , A61B19/00
CPC分类号： A61B17/1695 , A61B90/06 , A61B2017/00022 , A61B2017/00075 , A61B2017/00084 , A61B2017/00106 , A61B2017/00119 , A61B2090/062 , A61B2090/08021
摘要： A device for simultaneously monitoring the health of surgical drills and detecting proximity to critical structures during surgery is described herein. By using various sensors (e.g. microphones, accelerometers, temperature sensors, etc.), signals from the drill can be measured and analyzed. The processed signals can then be used to indicate the proximity of the drill bit to critical structures, such as the patient's brain, and identify drill health issues (e.g. worn bearings, misaligned rotational axis, etc.).
摘要翻译：本文描述了用于同时监测手术钻孔的健康并检测手术期间临界结构的接近度的装置。通过使用各种传感器（例如麦克风，加速度计，温度传感器等），可以测量和分析钻头的信号。然后，处理后的信号可用于指示钻头与关键结构（例如患者的大脑）的接近程度，并且识别钻孔健康问题（例如磨损的轴承，未对准的旋转轴线等）。

4. 发明授权

US08939832B2 Electronic gaming device with explosive scatters 有权
标题翻译：具有爆炸性散射的电子游戏装置
公开(公告)号：US08939832B2
公开(公告)日：2015-01-27
申请号：US13531837
申请日：2012-06-25
申请人： Timothy Ryan
发明人： Timothy Ryan
IPC分类号： G06F17/00 , G06F19/00
CPC分类号： G07F17/3209 , A63F13/005 , G07F17/3204 , G07F17/323 , G07F17/3239 , G07F17/3244 , G07F17/3251 , G07F17/3258 , G07F17/3267 , G07F17/34
摘要： Examples disclosed herein relate to systems and methods, which allow a player, the gaming device, and/or the gaming system to utilize exploding scatters. The electronic gaming device and/or method may utilize a plurality of reels. The plurality of reels may include one or more areas. The electronic gaming device and/or method may utilize a memory and a processor. The processor may generate one or more symbols to be located in the one or more areas. The one or more symbols may include a first expanding scatter symbol and a first dormant scatter symbol. The processor may modify the first dormant scatter symbol into an award value based on a first interaction determination.
摘要翻译：本文公开的示例涉及允许玩家，游戏装置和/或游戏系统利用爆炸散射的系统和方法。电子游戏装置和/或方法可以利用多个卷轴。多个卷轴可以包括一个或多个区域。电子游戏设备和/或方法可以利用存储器和处理器。处理器可以产生要位于一个或多个区域中的一个或多个符号。一个或多个符号可以包括第一扩展散射符号和第一休眠散射符号。处理器可以基于第一交互确定将第一休眠分散符号修改为奖励值。

5. 发明授权

US08739000B2 Multi-modal signal processing with linearization 有权
标题翻译：具有线性化的多模态信号处理
公开(公告)号：US08739000B2
公开(公告)日：2014-05-27
申请号：US13421328
申请日：2012-03-15
申请人： Timothy Ryan , Ravichandran Ramachandran
发明人： Timothy Ryan , Ravichandran Ramachandran
IPC分类号： H03M13/00 , G06F11/00 , G11B27/00
CPC分类号： H04L1/0026 , H04L1/203
摘要： A system for signal processing includes: a plurality of signal processing units associated with corresponding channels; a feedback channel for receiving a selected feedback signal through a selector of an output associated with each of the signal processing units; and a correlator connected to the feedback channel and having a receiving unit to receive the selected feedback signal, an error calculating unit to calculate an error based at least in part on the selected feedback signal, and a correction calculation unit to generate a correcting information based at least in part on the error. In some cases, the association between the signal processing units and the signal channels is configured based on a mode.
摘要翻译：一种用于信号处理的系统包括：与相应信道相关联的多个信号处理单元; 反馈通道，用于通过与每个信号处理单元相关联的输出的选择器接收所选择的反馈信号; 以及连接到所述反馈信道并具有接收单元以接收所选择的反馈信号的相关器，至少部分地基于所选择的反馈信号来计算误差的误差计算单元，以及基于所述反馈信号生成校正信息的校正计算单元至少部分是错误的。在一些情况下，信号处理单元和信号通道之间的关联是基于模式配置的。

6. 发明授权

US08600317B2 Linearization signal processing with context switching 失效
标题翻译：线性化信号处理与上下文切换
公开(公告)号：US08600317B2
公开(公告)日：2013-12-03
申请号：US13421354
申请日：2012-03-15
申请人： Timothy Ryan , Ravichandran Ramachandran
发明人： Timothy Ryan , Ravichandran Ramachandran
IPC分类号： H04B1/40
CPC分类号： H03F1/3247 , H03F3/24 , H04L27/368
摘要： A system for linearization signal processing with context switching comprises a plurality of signal processing units, a storage unit, a feedback channel, and a correlator. The plurality of signal processing units is associated with corresponding input data signals. The storage unit is to store context states associated with input data signals and corresponding feedback signals. The feedback channel is to convey feedback signals from outputs associated with the plurality of signal processing units. The correlator is coupled to the feedback channel and generates respective correcting information to be used by respective signal processing units, wherein a respective correcting information is based upon a context state and a feedback state associated with an input data signal.
摘要翻译：用于具有上下文切换的线性化信号处理的系统包括多个信号处理单元，存储单元，反馈信道和相关器。多个信号处理单元与相应的输入数据信号相关联。存储单元用于存储与输入数据信号和相应的反馈信号相关联的上下文状态。反馈信道用于传送与多个信号处理单元相关联的输出的反馈信号。相关器耦合到反馈信道并产生要由各个信号处理单元使用的相应校正信息，其中相应的校正信息基于与输入数据信号相关联的上下文状态和反馈状态。

7. 发明申请

US20100252470A1 Packaging Systems for Percutaneously Deliverable Bioprosthetic Valves 有权
标题翻译：用于经皮递送的生物麻醉阀的包装系统
公开(公告)号：US20100252470A1
公开(公告)日：2010-10-07
申请号：US12418668
申请日：2009-04-06
申请人： Timothy Ryan , Don Tran , Jeffrey Allen , Melissa Denton , Adam Podbelski
发明人： Timothy Ryan , Don Tran , Jeffrey Allen , Melissa Denton , Adam Podbelski
IPC分类号： A61B19/02 , A61F2/24
CPC分类号： A61F2/0095 , A61F2/2412 , A61F2/2418 , A61F2/2436 , A61F2/958 , A61F2002/9505 , A61F2002/9522
摘要： A packaging system is disclosed for shipping a prosthetic tissue valve in a storage solution and preparing and loading of the bioprosthetic valve onto a catheter-based delivery system. The packaging system includes a fluid tight container filled with the storage solution attached to a delivery catheter, wherein the container surrounds the prosthetic tissue valve that is in a pre-loaded position on the delivery catheter during shipment and storage. The prosthetic tissue valve may include an attachment mechanism that attaches to the delivery catheter to properly position the tissue valve for loading within the delivery catheter. In another embodiment where the prosthetic tissue valve is not attached to the delivery catheter during shipment, the attachment mechanism may interact with the prosthetic tissue valve shipping container to prevent the bioprosthetic valve from moving during shipment.
摘要翻译：公开了一种用于在存储溶液中运送假体组织瓣膜并且将生物假体瓣膜准备和装载到基于导管的输送系统上的包装系统。包装系统包括填充有附着到输送导管的储存溶液的流体密封容器，其中容器围绕在装运和储存期间处于输送导管的预加载位置的假肢组织瓣膜。假体组织瓣膜可以包括附接到输送导管以将组织瓣膜正确定位以装载在输送导管内的附接机构。在假体组织瓣膜在运输期间未附着到输送导管的另一实施例中，附接机构可与假体组织瓣膜运输容器相互作用，以防止生物假体瓣膜在运输期间移动。

8. 发明申请

US20070078514A1 Method of implanting an annuloplasty prosthesis 有权
标题翻译：植入瓣膜成形术假体的方法
公开(公告)号：US20070078514A1
公开(公告)日：2007-04-05
申请号：US11411260
申请日：2006-04-26
申请人： Timothy Ryan , Tirone David , Charles Tabor
发明人： Timothy Ryan , Tirone David , Charles Tabor
IPC分类号： A61F2/24
CPC分类号： A61B17/0469 , A61B17/0467 , A61B17/0483 , A61B17/06061 , A61B90/94 , A61B2017/0472 , A61B2017/0496 , A61B2090/061 , A61F2/2448 , A61F2/2466
摘要： A simplified and more easily employed tool for holding an implantable annuloplasty prosthesis during passage of sutures through the prosthesis and for conveniently and efficiently releasing the prosthesis from the tool. Separation of the implantable prosthesis and the tool may be conveniently accomplished without requiring the use of a sharp instrument. Attachment between the prosthesis and its surgical carrying tool can be accomplished in a suture-less fashion. The tool includes a suture management device in some embodiments for selectively receiving and maintaining sutures otherwise securing the prosthesis to tissue.
摘要翻译：一种简化且更容易使用的工具，用于在通过假体的缝线通过期间保持可植入瓣膜成形术假体，并且用于方便地和有效地将假体从工具释放。可以方便地实现可植入假体和工具的分离，而不需要使用尖锐的器械。假体和其手术携带工具之间的附接可以无缝缝合的方式实现。该工具在一些实施例中包括缝合线管理装置，用于选择性地接收和维持缝合线，否则将假体固定到组织。

9. 发明申请

US20070078510A1 Prosthetic cardiac and venous valves 审中-公开
标题翻译：假体心脏和静脉瓣
公开(公告)号：US20070078510A1
公开(公告)日：2007-04-05
申请号：US11527769
申请日：2006-09-26
申请人： Timothy Ryan
发明人： Timothy Ryan
IPC分类号： A61F2/06
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2/2475 , A61F2220/0016 , A61F2220/005 , A61F2220/0066
摘要： A prosthetic heart or venous valve, the valve including a central tissue structure with multiple tissue lobes extending from a common central area, wherein each of the lobes includes a longitudinal slot. The valve further includes a plurality of leaflets, each extending from the central tissue structure and positioned between two adjacent lobes, wherein each of the leaflets has a free end spaced from the central tissue structure, and also has a compressible and expandable stent frame with a plurality of extending arms, wherein each of the extending arms of the stent frame is positioned at least partially within one of the longitudinal slots of the central tissue structure.
摘要翻译：假体心脏或静脉瓣，所述瓣膜包括具有从公共中心区域延伸的多个组织瓣的中心组织结构，其中每个凸起部包括纵向槽。瓣膜还包括多个小叶，每个小叶从中心组织结构延伸并且定位在两个相邻瓣之间，其中每个小叶具有与中心组织结构隔开的自由端，并且还具有可压缩且可扩张的支架框架，其具有多个延伸臂，其中支架框架的每个延伸臂至少部分地位于中央组织结构的纵向狭槽之一内。

10. 发明申请

US20060282161A1 Valve annulus reduction system 审中-公开
标题翻译：阀环减压系统
公开(公告)号：US20060282161A1
公开(公告)日：2006-12-14
申请号：US10561113
申请日：2004-06-21
申请人： Rany Huynh , Eliot Bloom , Jack Lemmon , Timothy Ryan
发明人： Rany Huynh , Eliot Bloom , Jack Lemmon , Timothy Ryan
IPC分类号： A61F2/24
CPC分类号： A61B17/00234 , A61B17/0401 , A61B17/0487 , A61B2017/00243 , A61B2017/00783 , A61B2017/0417 , A61B2017/0451 , A61B2017/0461 , A61B2017/0464 , A61B2017/0496 , A61B2017/06052 , A61B2017/06176 , A61F2/2451 , A61F2/2481
摘要： System (10) for treating a dilated heart valve includes a dilivery device. Tension device (12) is slidably received within the lumen of delivery device (14) for delivery to and deployment at the treatment area. Delivery device (14) includes a plurality of arranged catheters including an inner catheter (26) within the lumen of an outer catheter (22). Tension device (12) includes a first anchor (16) attached to a second anchor (18).
摘要翻译：用于治疗扩张型心脏瓣膜的系统（10）包括通气装置。张紧装置（12）可滑动地容纳在输送装置（14）的内腔内，用于输送到处理区域并展开。输送装置（14）包括多个布置的导管，其包括在外导管（22）的内腔内的内导管（26）。张紧装置（12）包括附接到第二锚固件（18）的第一锚固件（16）。

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