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1. 发明申请

WO2004016775A3 PLANTS HAVING MODIFIED GROWTH AND A METHOD FOR MAKING THE SAME 审中-公开
标题翻译：具有改良生长的植物及其制备方法
公开(公告)号：WO2004016775A3
公开(公告)日：2004-05-06
申请号：PCT/EP0309142
申请日：2003-08-13
申请人： CROPDESIGN NV , DUDITS DENES , FRANKARD VALERIE , MIRONOV VLADIMIR , CSORDAS-TOTH EVA , HORVATH GABOR
发明人： DUDITS DENES , FRANKARD VALERIE , MIRONOV VLADIMIR , CSORDAS-TOTH EVA , HORVATH GABOR
IPC分类号： C07K14/415 , C12N15/29 , C12N15/82 , A01H5/00
CPC分类号： C07K14/415 , C12N15/8261 , Y02A40/146
摘要： The invention relates to plants having modified growth characteristics and a method for making plants having modified growth characteristics. The method involves reducing or substantially eliminating retinoblastoma 1 (Rb1) in a plant.
摘要翻译：本发明涉及具有改良生长特性的植物和一种具有改良生长特性的植物的制备方法。该方法涉及减少或基本上消除植物中的视网膜母细胞瘤1（Rb1）。

2. 发明申请

WO2008015263A3 PLANTS HAVING IMPROVED CHARACTERISTICS AND A METHOD FOR MAKING THE SAME 审中-公开
标题翻译：具有改进特性的植物及其制备方法
公开(公告)号：WO2008015263A3
公开(公告)日：2008-05-15
申请号：PCT/EP2007058043
申请日：2007-08-02
申请人： CROPDESIGN NV , FRANKARD VALERIE , MIRONOV VLADIMIR , REUZEAU CHRISTOPHE , SANZ MOLINERO ANA ISABEL
发明人： FRANKARD VALERIE , MIRONOV VLADIMIR , REUZEAU CHRISTOPHE , SANZ MOLINERO ANA ISABEL
IPC分类号： C12N15/82 , A01H1/00
CPC分类号： C12N15/8261 , C07K14/415 , C12N9/16 , C12N15/8241 , C12Y301/03011 , Y02A40/146
摘要： The present invention relates generally to the field of molecular biology and concerns a method for enhancing various economically important characteristics in plants. More specifically, the present invention concerns a method for improving yield-related traits, such as enhanced yield and/or enhanced growth, or modified content of storage compounds in plants by modulating expression in a plant of a nucleic acid encoding a GRP (Growht Related Protein) polypeptide. The present invention also concerns plants having modulated expression of a nucleic acid encoding a GRP polypeptide, which plants have improved characterisitics relative to control plants. The invention also provides hitherto unknown GRP-encoding nucleic acids, and constructs comprising the same, useful in performing the methods of the invention.
摘要翻译：本发明一般涉及分子生物学领域，涉及用于增强植物中各种经济重要特征的方法。更具体地，本发明涉及一种通过调节植物中编码GRP的核酸（Growht相关的）来提高产量相关性状例如增强的产量和/或增加的生长或修饰植物中储存化合物的含量的方法蛋白质）多肽。本发明还涉及具有调节的编码GRP多肽的核酸表达的植物，所述植物相对于对照植物具有改善的特征。本发明还提供迄今未知的编码GRP的核酸及包含其的构建体，可用于实施本发明的方法。

3. 发明申请

WO02083901A3 PLANT GROWTH REGULATING GENES, PROTEINS AND USES THEREOF 审中-公开
标题翻译：植物生长调节基因，蛋白质及其用途
公开(公告)号：WO02083901A3
公开(公告)日：2003-08-21
申请号：PCT/EP0204035
申请日：2002-04-11
申请人： CROPDESIGN NV , SAUTER MARGRET , LORBIECKE RENE , MIRONOV VLADIMIR , FRANKARD VALERIE , DILLEN WILLY , LEJEUNE PIERRE , BROEKAERT WILLEM
发明人： SAUTER MARGRET , LORBIECKE RENE , MIRONOV VLADIMIR , FRANKARD VALERIE , DILLEN WILLY , LEJEUNE PIERRE , BROEKAERT WILLEM
IPC分类号： C07K14/415 , C12N15/29 , C12N15/82 , A01H5/00 , C07K16/16 , C12Q1/68
CPC分类号： C12N15/8262 , C07K14/415 , C12N15/8237 , C12N15/8261 , Y02A40/146
摘要： Provided are methods for controlling or altering the growth characteristics of a plant or of an organ or tissue or cell of this plant. This method comprises introduction and/or expression of one or more Growth Regulating Proteins functional in a plant or parts thereof and/or one or more DNA sequences encoding such proteins. Another method comprises contacting a plant or plant tissue with the purified Growth Regulated Protein or the active product derived from it. Provided are also DNA sequences encoding plant Growth Regulating Protein(s) as well as methods for obtaining the same. Furthermore, vectors comprising said DNA sequences are described, wherein the DNA sequences are operatively linked to regulatory elements allowing expression in prokaryotic and/or eukaryotic host cells. In addition, proteins encoded by said DNA sequences, antibodies to said proteins and methods for their production are provided. Furthermore, regulatory sequences, which naturally regulate the expression of the above-described DNA sequences, are described. Methods for the identification of compounds being capable of interacting with said Growth Regulating Proteins are described as well. Furthermore, transgenic plant cells, plant tissues and plants containing the above-described DNA sequences and vectors are described, as well as the use of the aforementioned DNA sequences, vectors, proteins, antibodies, regulatory sequences and/or compounds identified by the method of the invention in plant cell and tissue culture, plant breeding and/or agriculture.
摘要翻译：提供了用于控制或改变植物或该植物的器官或组织或细胞的生长特性的方法。该方法包括在植物或其部分和/或编码这种蛋白质的一个或多个DNA序列中引入和/或表达一种或多种功能的生长调节蛋白。另一种方法包括使植物或植物组织与纯化的生长调节蛋白或其衍生的活性产物接触。还提供编码植物生长调节蛋白的DNA序列以及获得其的方法。此外，描述了包含所述DNA序列的载体，其中所述DNA序列可操作地连接到允许在原核和/或真核宿主细胞中表达的调节元件。此外，提供了由所述DNA序列编码的蛋白质，对所述蛋白质的抗体及其生产方法。此外，描述了调节序列，其自然调节上述DNA序列的表达。还描述了用于鉴定能够与所述生长调节蛋白相互作用的化合物的方法。此外，描述了含有上述DNA序列和载体的转基因植物细胞，植物组织和植物，以及使用上述DNA序列，载体，蛋白质，抗体，调节序列和/或化合物本发明在植物细胞和组织培养，植物育种和/或农业中。

4. 发明申请

WO0228893A2 NOVEL PLANT CYCLIN-DEPENDENT KINASE INHIBITORS 审中-公开
标题翻译：新型植物依赖性激酶抑制剂
公开(公告)号：WO0228893A2
公开(公告)日：2002-04-11
申请号：PCT/IB0101492
申请日：2001-06-29
申请人： CROPDESIGN NV , FRANKARD VALERIE MARIE NOELLE , PERES BOTA ADRIAN MARIUS , DROUAL ANNE MARIE , MIRONOV VLADIMIR , INZE DIRK , HATZFELD YVES
发明人： FRANKARD VALERIE MARIE-NOELLE , PERES BOTA ADRIAN MARIUS , DROUAL ANNE-MARIE , MIRONOV VLADIMIR , INZE DIRK , HATZFELD YVES
IPC分类号： C07K14/415 , C12N15/54 , C12N15/82 , C07K14/47 , A01H5/00 , C07K16/40 , C12N9/12 , G01N33/573
CPC分类号： C07K14/415 , C12N15/8261 , C12N15/8273 , Y02A40/146
摘要： The invention provides isolated nucleic acids molecules, designated ICK nucleic acid molecules, which encode novel plant cyclin-dependent kinase inhibitors. The invention also provides antisense nucleic acid molecules, gene silencing and recombinant expression vectors containing ICK nucleic acid molecules, host cells into which the expression vectors have been introduced, and transgenic plants in which an ICK gene has been introduced or disrupted. The invention still further provides isolated ICK proteins, fusion proteins, antigenic peptides and anti-ICK antibodies. Agricultural, diagnostic, and screening methods utilizing compositions of the invention are also provided.
摘要翻译：本发明提供编码新的植物细胞周期蛋白依赖性激酶抑制剂的分离的核酸分子，称为ICK核酸分子。本发明还提供了含有ICK核酸分子的反义核酸分子，基因沉默和重组表达载体，其中引入了表达载体的宿主细胞，以及引入或破坏ICK基因的转基因植物。本发明还进一步提供了分离的ICK蛋白，融合蛋白，抗原肽和抗ICK抗体。还提供了利用本发明组合物的农业，诊断和筛选方法。

5. 发明申请

WO2005059147A3 PLANTS HAVING MODIFIED GROWTH CHARACTERISTICS AND METHOD FOR MAKING THE SAME 审中-公开
标题翻译：具有改良生长特性的植物及其制备方法
公开(公告)号：WO2005059147A3
公开(公告)日：2006-04-20
申请号：PCT/EP2004053594
申请日：2004-12-17
申请人： CROPDESIGN NV , FRANKARD VALERIE , MIRONOV VLADIMIR , SANZ MOLINERO ANA ISABEL
发明人： FRANKARD VALERIE , MIRONOV VLADIMIR , SANZ MOLINERO ANA ISABEL
IPC分类号： C12N15/82 , A01H5/00 , C07K14/415
CPC分类号： C07K14/415 , C12N15/8261 , Y02A40/146
摘要： The present invention concerns a method for modifying the growth characteristics of plants by modulating expression in a plant of a nucleic acid sequence encoding a GRUBX protein and/or modulating activity and/or levels in a plant of a GRUBX protein. The present invention furthermore provides novel GRUBX proteins and nucleic acids encoding such proteins. The invention also relates to constructs comprising GRUBX encoding nucleic acids, and transgenic plants having modified growth characteristics, which plants have modulated expression of a nucleic acid encoding a GRUBX protein.
摘要翻译：本发明涉及一种通过调节植物中编码GRUBX蛋白的核酸序列表达和/或调节GRUBX蛋白植物中的活性和/或水平来修饰植物生长特性的方法。本发明还提供了编码这种蛋白质的新型GRUBX蛋白质和核酸。本发明还涉及包含GRUBX编码核酸的构建体和具有修饰生长特性的转基因植物，该植物已经调节了编码GRUBX蛋白质的核酸的表达。

6. 发明申请

WO2005061702A3 PLANTS HAVING INCREASED YIELD AND METHOD FOR MAKING THE SAME 审中-公开
标题翻译：具有提高产量的植物及其制备方法
公开(公告)号：WO2005061702A3
公开(公告)日：2005-11-17
申请号：PCT/EP2004053683
申请日：2004-12-22
申请人： CROPDESIGN NV , FRANKARD VALERIE , MIRONOV VLADIMIR
发明人： FRANKARD VALERIE , MIRONOV VLADIMIR
IPC分类号： C12N15/82 , A01H5/00
CPC分类号： C12N15/8261 , Y02A40/146
摘要： The invention concerns a method for increasing plant yield by introducing into a plant a cyclin A nucleic acid, preferably encoding a cyclin A protein, which cyclin A nucleic acid is operably linked to a seed-preferred promoter. By using this method, plant yield may be increased in optimal and sub-optimal growing conditions. The method results in plants having increased yield relative to corresponding wild type plants and relative to transgenic plants constitutively expressing cyclin A.
摘要翻译：本发明涉及通过向植物中导入细胞周期蛋白A核酸，优选编码细胞周期蛋白A蛋白，将细胞周期蛋白A核酸有效连接至种子优选启动子来增加植物产量的方法。通过使用该方法，植物产量可以在最佳和次优生长条件下增加。该方法导致植物相对于相应的野生型植物和相对于组成性表达细胞周期蛋白A的转基因植物而言具有增加的产量。

7. 发明申请

WO2007138070A2 PLANTS HAVING ENHANCED YIELD-RELATED TRAITS AND A METHOD FOR MAKING THE SAME 审中-公开
标题翻译：具有增强的相关旅行者的植物及其制造方法
公开(公告)号：WO2007138070A2
公开(公告)日：2007-12-06
申请号：PCT/EP2007055238
申请日：2007-05-30
申请人： CROPDESIGN NV , FRANKARD VALERIE , MIRONOV VLADIMIR , REUZEAU CHRISTOPHE
发明人： FRANKARD VALERIE , MIRONOV VLADIMIR , REUZEAU CHRISTOPHE
IPC分类号： C12N15/82 , C07K14/415 , C07K14/47
CPC分类号： C07K14/415 , C12N15/8218 , C12N15/8261 , Y02A40/146
摘要： The present invention relates generally to the field of molecular biology and concerns a method for improving various plant growth characteristics by modulating expression in a plant of a nucleic acid encoding a GRP (Growth-Related Protein). The present invention also concerns plants having modulated expression of a nucleic acid encoding a GRP, which plants have improved growth characteristics relative to corresponding wild type plants or other control plants. The invention also provides constructs useful in the methods of the invention. The GRP may be one of the following: Extensin Receptor-Like Kinase (ERLK), F- Box WD40 (FBXW) polypeptide, RAN-Binding Protein (RANBP), Golden2-like Transcription Factor (GLK), REV delta homeodomain leucine zipper domain polypepetide, CLE protein, and Seed Yield Regulator (SYR) protein.
摘要翻译：本发明一般涉及分子生物学领域，涉及通过调节植物中编码GRP（生长相关蛋白）的核酸的表达来改善各种植物生长特征的方法。本发明还涉及具有调节GRP核酸表达的植物，该植物相对于相应的野生型植物或其它对照植物具有改善的生长特性。本发明还提供了可用于本发明方法的构建体。 GRP可能是以下之一：拉伸素受体样激酶（ERLK），F盒WD40（FBXW）多肽，RAN-结合蛋白（RANBP），Golden2样转录因子（GLK），REVδ同源结构域亮氨酸拉链结构域多肽，CLE蛋白和种子产量调节剂（SYR）蛋白。

8. 发明申请

WO2005049646A3 "SEEDY1" NUCEIC ACIDS FOR MAKING PLANTS HAVING CHANGED GROWTH CHARACTERISTICS 审中-公开
标题翻译： “SEEDY1”NUCEIC ACIDS FOR MAKING PLUTS HAVEING CHANGED GROWTH CHARACTERISTICS
公开(公告)号：WO2005049646A3
公开(公告)日：2005-10-20
申请号：PCT/EP2004053030
申请日：2004-11-19
申请人： CROPDESIGN NV , FRANKARD VALERIE , MIRONOV VLADIMIR
发明人： FRANKARD VALERIE , MIRONOV VLADIMIR
IPC分类号： C07K14/415 , C12N15/82 , C12N15/29
CPC分类号： C12N15/8261 , C07K14/415 , Y02A40/146
摘要： The present invention concerns a method for modifying the growth characteristics of a plant relative to corresponding wild type plants, comprising modifying expression in a plant of a seedy1 nucleic acid and/or modifying the level and/or activity in a plant of a seedy1 protein. The invention also concerns novel constructs and novel seedy1 nucleic acid and protein sequences.
摘要翻译：本发明涉及一种改变植物相对于相应的野生型植物的生长特性的方法，其包括改变种子1核酸的植物中的表达和/或修饰seedy1蛋白的植物中的水平和/或活性。本发明还涉及新型构建体和新颖的seedy1核酸和蛋白质序列。

9. 发明申请

WO2005024029A3 PLANTS HAVING MODIFIED GROWTH CHARACTERISTICS AND METHOD FOR MAKING THE SAME 审中-公开
标题翻译：具有改良生长特性的植物及其制备方法
公开(公告)号：WO2005024029A3
公开(公告)日：2005-09-01
申请号：PCT/EP2004052035
申请日：2004-09-03
申请人： CROPDESIGN NV , BROEKAERT WILLEM , FRANKARD VALERIE , HATZFELD YVES , MIRONOV VLADIMIR
发明人： BROEKAERT WILLEM , FRANKARD VALERIE , HATZFELD YVES , MIRONOV VLADIMIR
IPC分类号： C12N9/12 , C12N15/82 , C12Q1/48 , A01H5/00
CPC分类号： C12N9/1205 , C12N15/8262 , C12Q1/485 , G01N2333/39 , G01N2500/10
摘要： The present invention concerns a method for modifying the growth characteristics of plants by modulating expression in a plant of a B-type CDK nucleic acid and/or modulating activity and/or levels in a plant of a B-type CDK protein. The invention also relates to transgenic plants having modified growth characteristics, which plants have modulated expression of a B-type CDK nucleic acid and/or modulated activity and/or levels in a plant of a B-type CDK protein relative to expression, activity and/or levels in corresponding wild-type plants. The present invention also provides a novel screening method for the identification of mutant CDKs having enhanced CDK activity relative to corresponding non-mutated CDKs. The present invention also provides a novel screening method for the identification of non-active CDKs that are able to bind to CKIs (cyclin dependent kinase inhibitors). The invention also provides mutant CDKs obtainable by the screening methods according to the invention.
摘要翻译：本发明涉及通过调节B型CDK核酸的植物表达和/或调节B型CDK蛋白的植物中的活性和/或水平来修饰植物生长特性的方法。本发明还涉及具有修饰的生长特性的转基因植物，相对于表达，活性，植物调节B型CDK核酸的表达和/或调节的活性和/或B型CDK蛋白的植物中的水平 /或相应野生型植物中的水平。本发明还提供了一种用于鉴定相对于相应的非突变CDKs具有增强的CDK活性的突变CDK的新型筛选方法。本发明还提供了用于鉴定能够结合CKI（细胞周期蛋白依赖性激酶抑制剂）的非活性CDK的新型筛选方法。本发明还提供可通过本发明的筛选方法获得的突变体CDK。

10. 发明申请

WO0144482A3 OPTIMIZED T-DNA TRANSFER AND VECTORS THEREFOR 审中-公开
标题翻译：优化的T-DNA转移和载体
公开(公告)号：WO0144482A3
公开(公告)日：2002-01-31
申请号：PCT/EP0012683
申请日：2000-12-13
申请人： CROPDESIGN NV , DEPICKER ANNA , MIRONOV VLADIMIR , TERRAS FRANKY , BROEKAERT WILLEM , BUCK SYLVIE DE , WILDE CHRIS DE
发明人： DEPICKER ANNA , MIRONOV VLADIMIR , TERRAS FRANKY , BROEKAERT WILLEM , DE BUCK SYLVIE , DE WILDE CHRIS
IPC分类号： A01H5/00 , A01H1/00 , A61K48/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/80 , C12N15/81 , C12N15/82 , C12R1/01
CPC分类号： C12N15/8213 , C12N15/8201 , C12N15/8205 , C12N2800/30 , C12N2810/65
摘要： The present invention relates to T-DNA vectors and methods for obtaining transgenic eukaryotes using said vectors. The transgenic eukaryotes are characterized in that they contain the T-DNA but not the illegitimately transferred vector backbone sequence. This is achieved by modifying the T-DNA borders such that they are more efficiently nicked or such that they allow elimination of illegitimately transferred vector backbone sequences by means of recombination.
摘要翻译：本发明涉及使用所述载体获得转基因真核生物的T-DNA载体和方法。转基因真核生物的特征在于它们含有T-DNA，而不是非法转移的载体骨架序列。这可以通过改变T-DNA边界来实现，使得它们更有效地切割，或者允许它们通过重组消除非法转移的载体骨架序列。

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