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1. 发明申请

WO02083901A3 PLANT GROWTH REGULATING GENES, PROTEINS AND USES THEREOF 审中-公开
标题翻译：植物生长调节基因，蛋白质及其用途
公开(公告)号：WO02083901A3
公开(公告)日：2003-08-21
申请号：PCT/EP0204035
申请日：2002-04-11
申请人： CROPDESIGN NV , SAUTER MARGRET , LORBIECKE RENE , MIRONOV VLADIMIR , FRANKARD VALERIE , DILLEN WILLY , LEJEUNE PIERRE , BROEKAERT WILLEM
发明人： SAUTER MARGRET , LORBIECKE RENE , MIRONOV VLADIMIR , FRANKARD VALERIE , DILLEN WILLY , LEJEUNE PIERRE , BROEKAERT WILLEM
IPC分类号： C07K14/415 , C12N15/29 , C12N15/82 , A01H5/00 , C07K16/16 , C12Q1/68
CPC分类号： C12N15/8262 , C07K14/415 , C12N15/8237 , C12N15/8261 , Y02A40/146
摘要： Provided are methods for controlling or altering the growth characteristics of a plant or of an organ or tissue or cell of this plant. This method comprises introduction and/or expression of one or more Growth Regulating Proteins functional in a plant or parts thereof and/or one or more DNA sequences encoding such proteins. Another method comprises contacting a plant or plant tissue with the purified Growth Regulated Protein or the active product derived from it. Provided are also DNA sequences encoding plant Growth Regulating Protein(s) as well as methods for obtaining the same. Furthermore, vectors comprising said DNA sequences are described, wherein the DNA sequences are operatively linked to regulatory elements allowing expression in prokaryotic and/or eukaryotic host cells. In addition, proteins encoded by said DNA sequences, antibodies to said proteins and methods for their production are provided. Furthermore, regulatory sequences, which naturally regulate the expression of the above-described DNA sequences, are described. Methods for the identification of compounds being capable of interacting with said Growth Regulating Proteins are described as well. Furthermore, transgenic plant cells, plant tissues and plants containing the above-described DNA sequences and vectors are described, as well as the use of the aforementioned DNA sequences, vectors, proteins, antibodies, regulatory sequences and/or compounds identified by the method of the invention in plant cell and tissue culture, plant breeding and/or agriculture.
摘要翻译：提供了用于控制或改变植物或该植物的器官或组织或细胞的生长特性的方法。该方法包括在植物或其部分和/或编码这种蛋白质的一个或多个DNA序列中引入和/或表达一种或多种功能的生长调节蛋白。另一种方法包括使植物或植物组织与纯化的生长调节蛋白或其衍生的活性产物接触。还提供编码植物生长调节蛋白的DNA序列以及获得其的方法。此外，描述了包含所述DNA序列的载体，其中所述DNA序列可操作地连接到允许在原核和/或真核宿主细胞中表达的调节元件。此外，提供了由所述DNA序列编码的蛋白质，对所述蛋白质的抗体及其生产方法。此外，描述了调节序列，其自然调节上述DNA序列的表达。还描述了用于鉴定能够与所述生长调节蛋白相互作用的化合物的方法。此外，描述了含有上述DNA序列和载体的转基因植物细胞，植物组织和植物，以及使用上述DNA序列，载体，蛋白质，抗体，调节序列和/或化合物本发明在植物细胞和组织培养，植物育种和/或农业中。

2. 发明专利

CA2444087A1 PLANT GROWTH REGULATING GENES, PROTEINS AND USES THEREOF 未知
公开(公告)号：CA2444087A1
公开(公告)日：2002-10-24
申请号：CA2444087
申请日：2002-04-11
申请人： CROPDESIGN NV , SAUTER MARGRET
发明人： BROEKAERT WILLEM , LORBIECKE RENE , FRANKARD VALERIE , MIRONOV VLADIMIR , LEJEUNE PIERRE , DILLEN WILLY , SAUTER MARGRET
IPC分类号： C07K14/415 , C12N15/29 , C12N15/82 , A01H5/00 , C07K16/16 , C12Q1/68
摘要： Provided are methods for controlling or altering the growth characteristics of a plant or of an organ or tissue or cell of this plant. This method comprises introduction and/or expression of one or more Growth Regulating Proteins functional in a plant or parts thereof and/or one or more DNA sequences encoding such proteins. Another method comprises contacting a plant or plant tissue with the purified Growth Regulated Protein or the active product derived from it. Provided are also DNA sequences encoding plant Growth Regulating Protein(s) as well as methods for obtaining the same. Furthermore, vectors comprising said DNA sequences are described, wherein the DNA sequences are operatively linked to regulatory elements allowing expression in prokaryotic and/or eukaryotic host cells. In addition, proteins encoded by said DNA sequences, antibodies to said proteins and methods for their production are provided. Furthermore, regulatory sequences, which naturally regulate the expression of the above-described DNA sequences, are described. Methods for the identification of compounds being capable of interacting with said Growth Regulating Proteins are described as well. Furthermore, transgenic plant cells, plant tissues and plants containing the above-described DNA sequences and vectors are described, as well as the use of the aforementioned DNA sequences, vectors, proteins, antibodies, regulatory sequences and/or compounds identified by the method of the invention in plant cell and tissue culture, plant breeding and/or agriculture.

3. 发明申请

WO0161020A3 ALTERATION OF GROWTH AND ADAPTATION UNDER HYPOXIC CONDITIONS 审中-公开
标题翻译：在高压条件下生长和适应的变化
公开(公告)号：WO0161020A3
公开(公告)日：2002-06-27
申请号：PCT/IB0100745
申请日：2001-02-16
申请人： CROPDESIGN NV
发明人： SAUTER MARGRET MARIA , LORBIECKE RENE
IPC分类号： A01H5/00 , C07K14/415 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/29 , C12N15/82 , A01H5/10 , A01N65/00 , C12N1/00
CPC分类号： C12N15/8261 , C07K14/415 , C12N15/8271 , C12N15/8297 , Y02A40/146
摘要： The present invention provides nucleotide sequences and corresponding amino acid sequences for a gene which confers the ability to adapt to low oxygen, i.e., hypoxic conditions. These sequences are referred to as SH2A and SH2A-like sequences. Genetic constructs and chimeric genes comprising these sequences are also provided. The nucleotide and amino acid sequences may be used to transform bacteria, yeasts, fungi, animal and plant species in order to modulate the level and/or activity of SH2A or SH2A-like protein. Also provided are transgenic plants, plant cells and host cells which express an SH2A or SH2A-like gene. Methods for modulating growth or survival of cultured cells under hypoxic conditions, and methods for alternating growth response in cells, tissues, or organs of an organism are also provided. In addition, methods for producing plants adapted to growth in hypoxic conditions, methods for improving water logging tolerance in a plant, methods for inducing gibberellin biosynthesis in a plant cell and methods of regulating an anaerobic response in a plant cell are provided by the present invention. The compositions and methodologies of the present invention find a myriad of uses in the horticultural, agricultural, medical, fermentation, and cell culture industries.
摘要翻译：本发明提供了赋予适应低氧，即缺氧条件的能力的基因的核苷酸序列和相应的氨基酸序列。这些序列被称为SH2A和SH2A样序列。还提供了包含这些序列的遗传构建体和嵌合基因。核苷酸和氨基酸序列可用于转化细菌，酵母，真菌，动物和植物物种，以调节SH2A或SH2A样蛋白的水平和/或活性。还提供了表达SH2A或SH2A样基因的转基因植物，植物细胞和宿主细胞。还提供了在缺氧条件下调节培养细胞的生长或存活的方法，以及生物体的细胞，组织或器官中交替生长反应的方法。此外，本发明提供了适于生长缺氧条件的植物的方法，植物中提高耐水耐受性的方法，诱导植物细胞中赤霉素生物合成的方法和调节厌氧反应的方法。本发明的组合物和方法在园艺，农业，医疗，发酵和细胞培养工业中发现无数的用途。

4. 发明专利

AU5058701A Alteration of growth and adaptation under hypoxic conditions 未知
公开(公告)号：AU5058701A
公开(公告)日：2001-08-27
申请号：AU5058701
申请日：2001-02-16
申请人： CROPDESIGN NV
发明人： SAUTER MARGRET MARIA , LORBIECKE RENE
IPC分类号： A01H5/00 , C07K14/415 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/29 , C12N15/82 , C12N1/00 , A01N65/00
摘要： The present invention provides nucleotide sequences and corresponding amino acid sequences for a gene which confers the ability to adapt to low oxygen, i.e., hypoxic conditions. These sequences are referred to as SH2A and SH2A-like sequences. Genetic constructs and chimeric genes comprising these sequences are also provided. The nucleotide and amino acid sequences may be used to transform bacteria, yeasts, fungi, animal and plant species in order to modulate the level and/or activity of SH2A or SH2A-like protein. Also provided are transgenic plants, plant cells and host cells which express an SH2A or SHA2A-like gene. Methods for modulating growth or survival of cultured cells under hypoxic conditions, and methods for altering growth response in cells, tissues, or organs of an organism are also provided. In addition, methods for producing plants adapted to growth in hypoxic conditions, methods for improving water logging tolerance in a plant, methods for inducing gibberellin biosynthesis in a plant cell and methods of regulating an anaerobic response in a plant cell are provided by the present invention. The compositions and methodologies of the present invention find a myriad of uses in the horticultural, agricultural, medical, fermentation, and cell culture industries.

5. 发明专利

CA2399137A1 ALTERATION OF GROWTH AND ADAPTATION UNDER HYPOXIC CONDITIONS 未知
公开(公告)号：CA2399137A1
公开(公告)日：2001-08-23
申请号：CA2399137
申请日：2001-02-16
申请人： CROPDESIGN NV
发明人： SAUTER MARGRET MARIA , LORBIECKE RENE
IPC分类号： A01H5/00 , C07K14/415 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/29 , C12N15/82 , A01N65/00 , C12N1/00 , A01H5/10
摘要： The present invention provides nucleotide sequences and corresponding amino acid sequences for a gene which confers the ability to adapt to low oxygen, i.e., hypoxic conditions. These sequences are referred to as SH2A and SH2A- like sequences. Genetic constructs and chimeric genes comprising these sequences are also provided. The nucleotide and amino acid sequences may be used to transform bacteria, yeasts, fungi, animal and plant species in order to modulate the level and/or activity of SH2A or SH2A-like protein. Also provided are transgenic plants, plant cells and host cells which express an SH2A or SH2A-like gene. Methods for modulating growth or survival of culture d cells under hypoxic conditions, and methods for alternating growth response in cells, tissues, or organs of an organism are also provided. In addition, methods for producing plants adapted to growth in hypoxic conditions, method s for improving water logging tolerance in a plant, methods for inducing gibberellin biosynthesis in a plant cell and methods of regulating an anaerobic response in a plant cell are provided by the present invention. Th e compositions and methodologies of the present invention find a myriad of use s in the horticultural, agricultural, medical, fermentation, and cell culture industries.

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