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1. 发明申请

WO2004047687A1 STENT TISSUE GRAFT PROSTHESIS 审中-公开
公开(公告)号：WO2004047687A1
公开(公告)日：2004-06-10
申请号：PCT/US2003/037365
申请日：2003-11-21
申请人： COOK INCORPORATED , COOK BIOTECH, INC. , OREGON HEALTH AND SCIENCE UNIVERSITY
发明人： PAVCNIK, Dusan , FETTE, Clay, D. , MEAD, Jason, A. , OBERMILLER, Joseph, F. , PARKER, Fred, T.
IPC分类号： A61F2/06
CPC分类号： A61L27/3633 , A61F2/07 , A61F2/852 , A61F2/89 , A61F2/91 , A61F2/95 , A61F2002/065 , A61F2002/075 , A61F2230/0054 , A61F2250/0063 , A61L27/3629
摘要： A stent tissue graft prosthesis (20) for repairing, excluding and/or reinforcing a vessel, duct and the like in a patient. The prosthesis includes an inner expandable stent (21) of which a tissue graft (24) and preferably a multilayered tissue construct (33) is disposed thereon for application to the host tissue of a vessel, duct and the like. The tissue construct includes an extracellular matrix material (36) such as small intestine submucosa (37) for remodeling the host tissue into the prosthesis. The prosthesis further includes an outer tubular member (25) such as an outer expandable stent (44) for retaining the tissue graft on the inner stent. The ends of the inner and outer stents are coincident with or extend beyond the ends of the tissue graft to prevent eversion or fold back of the tissue graft during withdrawal of a delivery catheter in a placement procedure.
摘要翻译：一种用于在患者体内修复，排除和/或加强血管，导管等的支架组织移植假体（20）。假体包括内部可扩张支架（21），其上设置有组织移植物（24）并且优选地多层组织构建体（33），用于施用到血管，管道等的宿主组织。组织构建体包括细胞外基质材料（36），例如用于将宿主组织重塑成假体的小肠粘膜下层（37）。假体还包括外部管状构件（25），例如用于将组织移植物保持在内部支架上的外部可扩张支架（44）。内部和外部支架的端部与组织移植物的端部重合或延伸超过组织移植物的端部，以防止在放置过程中递送导管撤出期间组织移植物的外翻或折回。

2. 发明授权

EP1565128B1 STENT TISSUE GRAFT PROSTHESIS 有权
标题翻译： STENTGEFÄSSTRANSPLANTAT
公开(公告)号：EP1565128B1
公开(公告)日：2007-11-07
申请号：EP03787005.2
申请日：2003-11-21
申请人： Cook Incorporated , Cook Biotech Incorporated , Oregon Health and Science University
发明人： PAVCNIK, Dusan , FETTE, Clay, D. , MEAD, Jason, A. , OBERMILLER, Joseph, F. , PARKER, Fred, T.
IPC分类号： A61F2/06
CPC分类号： A61L27/3633 , A61F2/07 , A61F2/852 , A61F2/89 , A61F2/91 , A61F2/95 , A61F2002/065 , A61F2002/075 , A61F2230/0054 , A61F2250/0063 , A61L27/3629
摘要： A stent tissue graft prosthesis (20) for repairing, excluding and/or reinforcing a vessel, duct and the like in a patient. The prosthesis includes an inner expandable stent (21) of which a tissue graft (24) and preferably a multilayered tissue construct (33) is disposed thereon for application to the host tissue of a vessel, duct and the like. The tissue construct includes an extracellular matrix material (36) such as small intestine submucosa (37) for remodeling the host tissue into the prosthesis. The prosthesis further includes an outer tubular member (25) such as an outer expandable stent (44) for retaining the tissue graft on the inner stent. The ends of the inner and outer stents are coincident with or extend beyond the ends of the tissue graft to prevent eversion or fold back of the tissue graft during withdrawal of a delivery catheter in a placement procedure.

3. 发明公开

EP1565128A1 STENT TISSUE GRAFT PROSTHESIS 有权
标题翻译：覆膜支架植入血管
公开(公告)号：EP1565128A1
公开(公告)日：2005-08-24
申请号：EP03787005.2
申请日：2003-11-21
申请人： Cook Incorporated , Cook Biotech Incorporated , Oregon Health and Science University
发明人： PAVCNIK, Dusan , FETTE, Clay, D. , MEAD, Jason, A. , OBERMILLER, Joseph, F. , PARKER, Fred, T.
IPC分类号： A61F2/06
CPC分类号： A61L27/3633 , A61F2/07 , A61F2/852 , A61F2/89 , A61F2/91 , A61F2/95 , A61F2002/065 , A61F2002/075 , A61F2230/0054 , A61F2250/0063 , A61L27/3629
摘要： A stent tissue graft prosthesis (20) for repairing, excluding and/or reinforcing a vessel, duct and the like in a patient. The prosthesis includes an inner expandable stent (21) of which a tissue graft (24) and preferably a multilayered tissue construct (33) is disposed thereon for application to the host tissue of a vessel, duct and the like. The tissue construct includes an extracellular matrix material (36) such as small intestine submucosa (37) for remodeling the host tissue into the prosthesis. The prosthesis further includes an outer tubular member (25) such as an outer expandable stent (44) for retaining the tissue graft on the inner stent. The ends of the inner and outer stents are coincident with or extend beyond the ends of the tissue graft to prevent eversion or fold back of the tissue graft during withdrawal of a delivery catheter in a placement procedure.

4. 发明申请

WO2010120671A1 EVERTING DEPLOYMENT SYSTEM AND HANDLE 审中-公开
标题翻译：代表部署制度和手段
公开(公告)号：WO2010120671A1
公开(公告)日：2010-10-21
申请号：PCT/US2010/030696
申请日：2010-04-12
申请人： COOK INCORPORATED , WILLIAM COOK EUROPE APS , PARKER, Fred, T. , HANSEN, Palle, M.
发明人： PARKER, Fred, T. , HANSEN, Palle, M.
IPC分类号： A61F2/84
CPC分类号： A61F2/97 , A61F2/95 , A61F2/966 , A61F2002/9517 , A61F2002/9522 , A61F2250/0039 , A61L29/085
摘要： A stent deployment system, handle, and method of loading of a medical device are provided. The system includes an outer catheter having an inner liner extending past the end of the outer catheter and an inner catheter disposed within the outer catheter. The inner liner is inverted and attached to the inner catheter. Relative movement between the outer and the inner catheters can urge the inner liner to peel away from the medical device. A handle is disposed at the proximal end of the outer catheter, and may include a splitter configured to slice the wall of the tubular member. The handle may also include a rotatable mechanism that can be attached to the tubular member. Rotation of the rotatable mechanism retracts a portion of the tubular member into the handle and winds the sliced portion about the rotatable mechanism.
摘要翻译：提供了支架部署系统，手柄和装载医疗装置的方法。该系统包括具有延伸穿过外导管的端部的内衬套和设置在外导管内的内导管的外导管。内衬被倒置并连接到内导管上。外导管和内导管之间的相对运动可促使内衬从医疗装置剥离。手柄设置在外导管的近端处，并且可以包括被配置为切割管状构件的壁的分流器。手柄还可以包括可连接到管状构件的可旋转机构。可旋转机构的旋转将管状构件的一部分缩回到手柄中并围绕可旋转机构卷绕切片部分。

5. 发明申请

WO2008112242A2 WOVEN FABRIC WITH SHAPE MEMORY ELEMENT STRANDS 审中-公开
标题翻译：具有形状记忆元件的WOVEN织物
公开(公告)号：WO2008112242A2
公开(公告)日：2008-09-18
申请号：PCT/US2008/003251
申请日：2008-03-12
申请人： COOK INCORPORATED , CARLSON, James, M. , KUPPURATHANAM, Shyam , PARKER, Fred, T. , TODD, Rebecca, S.
发明人： CARLSON, James, M. , KUPPURATHANAM, Shyam , PARKER, Fred, T. , TODD, Rebecca, S.
IPC分类号： A61L31/02 , A61L31/04 , A61L31/14
CPC分类号： A61F2/90 , A61F2/06 , A61F2/07 , A61F2002/075 , A61F2210/0014 , A61L31/022 , A61L31/041 , A61L31/14 , A61L2400/16 , C08L2201/12 , D02G3/12 , D02G3/448 , D03D3/02 , D03D13/004 , D03D13/008 , D03D15/00 , D03D15/08 , D10B2101/20 , D10B2321/021 , D10B2321/022 , D10B2321/042 , D10B2331/04 , D10B2331/10 , D10B2401/046 , D10B2401/061 , D10B2509/06
摘要： A woven fabric for use in an implantable medical device, such as a stented graft member, comprises shape memory element strands (100) woven with textile strands (110, 115). At least one of the shape memory element strands (100) has at least one float of at least five textile strands between binding points. The shape memory element strands may be heated and cooled before the weaving process, and then heated again after the weaving process.
摘要翻译：用于可植入医疗装置（例如支架移植物构件）中的机织织物包括用织物股线（110,115）编织的形状记忆元件股线（100）。至少一个形状记忆元件股线（100）在结合点之间具有至少一个至少五个纺织股线的浮子。形状记忆元件股线可以在织造过程之前被加热和冷却，然后在织造过程之后再次加热。

6. 发明申请

WO2006031874A1 LARGE DIAMETER SHEATH 审中-公开
标题翻译：大直径的沙子
公开(公告)号：WO2006031874A1
公开(公告)日：2006-03-23
申请号：PCT/US2005/032716
申请日：2005-09-14
申请人： WILLIAM A. COOK AUSTRALIA PTY. LTD. , COOK INCORPORATED , HARTLEY, David, Ernest , DREWES, David, A., Jr. , PARKER, Fred, T. , DITTMAN, Jay, A.
发明人： HARTLEY, David, Ernest , DREWES, David, A., Jr. , PARKER, Fred, T. , DITTMAN, Jay, A.
IPC分类号： A61M25/06 , A61M25/00
CPC分类号： A61F2/95 , A61F2/966 , A61M25/005 , A61M25/0053 , A61M25/0662 , A61M2025/0059
摘要： A large diameter, flexible, kink-resistant and rotatable introducer sheath (10) for percutaneous delivery of a contained and implantable medical device in the vasculature of a patient. The introducer sheath includes a reinforcement such as a flat wire coil (23) fitted about an inner, lubricous material such as polytetrafluoroethylene tube (22). A wire braid (25) is placed around the coil to give good transfer of rotational forces. An outer tube (27) of a heat formable polyamide material is heat formed and compressed through the spaces between the wires of the braid and turns of the wire coil to mechanically connect the outer tube to the roughened outer surface of the inner tube. The durometer of the outer tube can be varied to effect the flexibility of the sheath. A radiopaque marker (42) is positioned at the distal end of the coil and around the inner tube for radiographic visualization.
摘要翻译：用于经皮递送患者脉管系统中的容纳和可植入的医疗装置的大直径的，柔性的，扭结的和扭转的导引套（10）。引导器护套包括诸如扁丝线圈（23）之类的加强件，该扁线线圈围绕诸如聚四氟乙烯管（22）的内部润滑材料安装。线圈编织物（25）围绕线圈放置，以提供良好的转动力传递。可热成型的聚酰胺材料的外管（27）通过编织线的线间和线圈的匝之间的空间被热形成和压缩，以将外管机械地连接到内管的粗糙的外表面。可以改变外管的硬度以影响护套的柔性。不透射线的标记（42）位于线圈的远端并且围绕内管定位用于放射照相可视化。

7. 发明申请

WO2010021908A1 INTRODUCER SHEATH HAVING DUAL REINFORCING ELEMENTS 审中-公开
标题翻译：介绍具有双重增强元素的树脂
公开(公告)号：WO2010021908A1
公开(公告)日：2010-02-25
申请号：PCT/US2009/053701
申请日：2009-08-13
申请人： COOK INCORPORATED , PARKER, Fred, T. , CRABTREE, Christopher, B.
发明人： PARKER, Fred, T. , CRABTREE, Christopher, B.
IPC分类号： A61M25/00
CPC分类号： A61M25/005 , A61M25/0045 , A61M25/0053
摘要： An introducer sheath for deploying a stent to a target site within a body passageway of a patient. The introducer sheath includes a tubular inner liner having a proximal portion, a distal portion, and an outer surface. A first reinforcing element, and a second reinforcing element are positioned along the outer surface of the inner liner. The first reinforcing element comprises a braid the second reinforcing element comprises a coil. The braid is positioned at the proximal portion of the inner liner and extends distally therefrom. The coil is positioned at the distal portion longitudinally adjacent the braid. The braid has a length that may extend about 90% of the length of the sheath. An outer jacket is positioned longitudinally around the reinforcing elements, and is connected to the inner liner between the respective wires of the braid and the coil.
摘要翻译：用于将支架部署到患者的身体通道内的目标部位的引导器护套。引导器护套包括具有近端部分，远侧部分和外表面的管状内衬。第一增强元件和第二加强元件沿着内衬的外表面定位。第一增强元件包括编织物，第二增强元件包括线圈。编织物定位在内衬的近端部分并从其向远侧延伸。线圈定位在纵向部分的纵向附近的编织物处。编织物的长度可以延伸到护套长度的大约90％。外护套围绕加强元件纵向定位，并且连接到编织物和线圈的各个线之间的内衬。

8. 发明申请

WO2007059349A1 FOAM EMBOLIC PROTECTION DEVICE 审中-公开
标题翻译：泡沫保护装置
公开(公告)号：WO2007059349A1
公开(公告)日：2007-05-24
申请号：PCT/US2006/044928
申请日：2006-11-17
申请人： COOK INCORPORATED , MAGNUSON, Mark, A. , PARKER, Fred, T.
发明人： MAGNUSON, Mark, A. , PARKER, Fred, T.
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61L31/022 , A61L31/146 , A61L2400/16
摘要： An embolic protection device includes a foam body attached to a plurality of flexible struts. The foam body has a generally conical geometry and the bottom of the conical geometry having a generally conical recess. The filter portion has pores sized such that blood cells can pass through the foam body, but larger material such as objects would be trapped in the recess. Each strut is attached along the periphery of the foam body and extend from the first end of the foam body to a connection point located proximate the first end.
摘要翻译：栓塞保护装置包括附接到多个柔性支柱的泡沫体。泡沫体具有大致圆锥形的几何形状，圆锥形几何形状的底部具有大致锥形的凹部。过滤器部分具有尺寸使得血细胞可以通过泡沫体的孔，但是更大的材料例如物体将被困在凹部中。每个支柱沿着泡沫体的周边附着并且从泡沫体的第一端延伸到靠近第一端的连接点。

9. 发明申请

WO2006071915A2 UNIDIRECTIONAL DELIVERY SYSTEM 审中-公开
标题翻译： UNIDIRECTIONAL交付系统
公开(公告)号：WO2006071915A2
公开(公告)日：2006-07-06
申请号：PCT/US2005/047184
申请日：2005-12-27
申请人： COOK INCORPORATED
发明人： BAKER, Deborah, A. , PURDY, James, D. , PARKER, Fred, T.
IPC分类号： A61F2/84
CPC分类号： A61F2/966 , A61F2/95 , A61F2002/9517
摘要： A tubular prosthesis delivery system (20) has an inner tubular member (24) having a distal end (26) including a prosthesis-carrying portion (28) and a proximal end (30) generally intended to remain outside the patient. An outer tubular member (32) has a distal end (34) spaced from the prosthesis-carrying portion (28) of the inner member (24). A coupling member (36) couples the inner and outer tubular members (24, 32) to each other in fixed relationship generally at a location intended to remain outside the patient. An intermediate tubular member (38) located between the inner and outer tubular members has a distal end (40) adapted to cover the tubular prosthesis (22) and a proximal end (42) that projects proximally beyond the proximal ends (30, 44) of both the inner and outer tubular members (24, 32), and a slot (46) receiving the coupling member (36). The proximally projecting end (42) of the intermediate tubular member (38) is longitudinally movable with respect to the coupled inner and outer tubular members (24, 32) by a distance sufficient to retract the intermediate tubular member distal end (34) from any position covering the prosthesis (22) carried by the inner member (24).
摘要翻译：管状假体递送系统（20）具有内部管状构件（24），所述内部管状构件（24）具有包括假体承载部分（28）的远端（26）和通常旨在保持在患者外部的近端（30）。外部管状构件（32）具有与内部构件（24）的假体承载部分（28）间隔开的远端（34）。联接构件（36）以固定关系将内管状构件（24）与外管状构件（32）彼此连接，大致位于旨在保持在患者外部的位置。位于内管状构件和外管状构件之间的中间管状构件（38）具有适于覆盖管状假体（22）的远端（40）和近端突出超过近端（30,44）的近端（42）内部和外部管状构件（24,32）两者以及容纳联接构件（36）的槽（46）。中间管状构件（38）的近端突出的端部（42）可相对于联接的内部和外部管状构件（24,32）纵向移动一定距离，足以将中间管状构件远端（34）从任何覆盖由内部构件（24）承载的假体（22）的位置。

10. 发明申请

WO2005011535A2 PROSTHETIC VALVE FOR IMPLANTATION IN A BODY VESSEL 审中-公开
标题翻译：用于植入体内的浮选阀
公开(公告)号：WO2005011535A2
公开(公告)日：2005-02-10
申请号：PCT/US2004/024969
申请日：2004-07-30
申请人： COOK INCORPORATED , CASE, Brian, C. , OSBORNE, Thomas, A. , FLAGLE, Jacob, A. , PARKER, Fred, T.
发明人： CASE, Brian, C. , OSBORNE, Thomas, A. , FLAGLE, Jacob, A. , PARKER, Fred, T.
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2220/0008 , A61F2220/0016 , A61F2230/0067 , A61F2230/0078 , A61F2230/008 , A61F2250/0063
摘要： Prosthetic valves for implantation in a body vessel are provided. Prosthetic valves according to the invention comprise first and second frame members and a graft member at least partially disposed between the first and second frame members. The graft member forms a valve that permits fluid flow through the body vessel in a first direction and substantially prevents fluid flow through the body vessel in a second, opposite direction.
摘要翻译：提供用于植入体内的假体瓣膜。根据本发明的假体瓣膜包括第一和第二框架构件以及至少部分地设置在第一和第二框架构件之间的移植构件。移植物构件形成允许流体沿第一方向流过身体容器的阀，并且基本上防止流体沿第二相反方向流过身体血管。

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