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1. 发明申请

WO2003077656A1 4-AMINOPYRIMIDINES AND THEIR USE FOR THE ANTIMICROBIAL TREATMENT OF SURFACES 审中-公开
标题翻译： 4-氨基嘧啶及其在表面抗微生物处理中的应用
公开(公告)号：WO2003077656A1
公开(公告)日：2003-09-25
申请号：PCT/EP2003/002438
申请日：2003-03-10
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , MARQUAIS-BIENEWALD, Sophie , HÖLZL, Werner , HAAP, Wolfgang , PREUSS, Andrea , MEHLIN, Andreas
发明人： MARQUAIS-BIENEWALD, Sophie , HÖLZL, Werner , HAAP, Wolfgang , PREUSS, Andrea , MEHLIN, Andreas
IPC分类号： A01N43/54
CPC分类号： C07D239/42 , A01N43/54 , A01N43/78 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/12 , C07D405/14 , C07D409/04 , C07D417/04
摘要： Use of 4-aminopyrimidines of formula (1), wherein R 1, R 2, R 3 , R 4 and R 5 are as described in the description in the antimicrobial treatment of surfaces.
摘要翻译：使用式（1）的4-氨基嘧啶，其中R 1，R 2，R 3，R 4和R 5如表述的抗微生物处理中描述的那样。

2. 发明申请

WO2005011758A2 USE OF SUBSTITUTED 2,4-BIS(ALKYLAMINO)PYRIMIDINES 审中-公开
标题翻译：取代的2,4-BIS（亚苄基）嘧啶的使用
公开(公告)号：WO2005011758A2
公开(公告)日：2005-02-10
申请号：PCT/EP2004/051516
申请日：2004-07-16
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , MARQUAIS-BIENEWALD, Sophie , HÖLZL, Werner , PREUSS, Andrea , MEHLIN, Andreas
发明人： MARQUAIS-BIENEWALD, Sophie , HÖLZL, Werner , PREUSS, Andrea , MEHLIN, Andreas
IPC分类号： A61L2/18
CPC分类号： A61Q17/005 , A01N43/54 , A61K8/4953 , A61L2/16 , A61L2/18 , A61Q11/00 , C11D3/28 , C11D3/48 , D06M13/355 , Y10T442/2525
摘要： The use of 2,4-bis(alkylamino)pyrimidines of formula (1) R 1 is C 1 -C 12 alkyl or C 6 -C 10 laryl; R 2 is hydrogen or C 1 -C 12 alkyl; or R 1 and R 2 together forma radical of formula (1 a) R' and R" are each independently of the other hydrogen, C 1 -C 6 alkyl or C 1 -C 6 alkoxy, R 3 and R 5 are each independently of the other hydrogen or C 1 -C 8 alkyl; R 4 is C 1 -C 20 alkyl, unsubstituted phenyl, C 6 -C 10 aryl, C 6 -C 10 aryl-C 1 -C 6 alkyl, hydroxy-C 1 -C 6 alkyl, di-C 1 -C 6 al-kylamino-C 1 -C 6 aIkyl, mono-C 1 -C 6 alkylamino-C 1 -C 6 alkyl, -(CH 2 )2-(O-(CH 2 ) 2 ) 1-4 -OH or -(CH 2 ) 2 -(O-(CH 2 ) 2 ) 1-4 -NH 2 ; R 6 is C 1 -C 20 alkyl, C 6 -C 10 aryl, C 6 -C 10 aryl-C 1 -C 6 alkyl, hydroxy-C 1 -C 6 alkyl, di-C 1 C 6 alkylamino-C 1 -C 6 alkyl, mono-C 1 -C 6 alkylamino-C 1 -C 6 alkyl, -(CH 2 ) 2 -(O-(CH 2 ) 2 ) 1-4 -OH or -(CH 2 ) 2 -(O-(CH 2 ) 2 ) 1-4 -NH 2 ; or R 3 and R 4 and/or R 5 and R 6 , together form a pyrrolidine, piperidine, hexamethyleneimine or morpholine ring; in the antimicrobial treatment of surfaces.
摘要翻译：式（1）R 1的2,4-双（烷基氨基）嘧啶的用途是C 1 -C 12烷基或C 6 -C 10芳基; R2是氢或C1-C12烷基; 或者R 1和R 2一起形成式（1a）的基团，R'和R“各自独立地为氢，C 1 -C 6烷基或C 1 -C 6烷氧基，R 3和R 5各自独立地为氢或C 1 -C 8烷基; R 4 是C 1 -C 20烷基，未取代的苯基，C 6 -C 10芳基，C 6 -C 10芳基-C 1 -C 6烷基，羟基-C 1 -C 6烷基，二-C 1 -C 6烷基氨基-C 1 -C 6烷基，单-C 1 -C 6烷基氨基-C 1 -C 6烷基， - （ CH2）2-（O-（CH2）2）1-4-OH或 - （CH2）2-（O-（CH2）2）1-4-NH2; R6是C1-C20烷基，C6-C10芳基， C 1 -C 10芳基-C 1 -C 6烷基，羟基-C 1 -C 6烷基，二-C 1 -C 6烷基氨基-C 1 -C 6烷基，单-C 1 -C 6烷基氨基-C 1 -C 6烷基， - （CH 2）2 - （O-（CH 2）2）1-4 -OH或 - （CH2）2-（O-（CH2）2）1-4-NH2;或R3和R4和/或R5和R6一起形成吡咯烷，哌啶，六亚甲基亚胺或吗啉环;在表面的抗微生物处理中。

3. 发明申请

WO2004035521A1 BIS-ALKYLBENZYLAMINES 审中-公开
标题翻译： BIS-烷基苯甲胺
公开(公告)号：WO2004035521A1
公开(公告)日：2004-04-29
申请号：PCT/EP2003/011384
申请日：2003-10-14
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , MARQUAIS-BIENEWALD, Sophie , HÖLZL, Werner , PREUSS, Andrea , MEHLIN, Andreas , BRUNNER, Frédéric
发明人： MARQUAIS-BIENEWALD, Sophie , HÖLZL, Werner , PREUSS, Andrea , MEHLIN, Andreas , BRUNNER, Frédéric
IPC分类号： C07C211/27
CPC分类号： C07C211/27 , A01N33/04 , A01N33/08 , A01N43/16 , A01N43/46 , A01N43/60 , A01N43/84 , A61K8/41 , A61Q5/02 , A61Q11/00 , A61Q15/00 , A61Q17/005 , C07C211/35 , C07C215/14 , C07C217/08 , C07C2601/14 , C07D295/02 , C07D295/023 , C07D295/185 , C07D307/52
摘要： Compounds of Formula (1), wherein R 1 is hydrogen; C 1 -C 18 alkyl; trifluoromethyl; C 3 -C 8 cycloalkyl; phenyl-C 1 -C 5 alkyl; phenyl-C 1 -C 5 alkoxy; mono- or di-N-C 1 -C 5 alkylamino-C 1 -C 5 alkyl; amino-di-N-C 1 -C 5 alkylamino-C 1 -C 5 alkyl; C 1 -C 5 alkoxy-C 1 -C 5 alkyl; R 2 is C 2 -C 20 alkyl; hydroxy-C 1 -C 20 alkyl; phenyl; phenyl-C 1 -C 5 alkyl; phenyl-C 1 -C 5 alkoxy; mono- or di-N-C 1 -C 5 alkylamino-C 1 -C 5 alkyl; amino-di-N-C 1 -C 5 alkylamino-C 1 -C 5 alkyl; or heteroaryl-C 1 -C 5 alkyl; or R 1 and R 2 together with the nitrogen atom bonding them form a 5- to 7-membered monocyclic heterocyclic ring; are described. They are suitable for the antimicrobial treatment of surfaces, especially as antimicrobial active ingredients against gram-positive and gram-negative bacteria.
摘要翻译：式（1）的化合物，其中R 1是氢; C1-C18烷基; 三氟甲基; C3-C8环烷基; 苯基-C 1 -C 5烷基; 苯基-C 1 -C 5烷氧基; 单或二-N-C 1 -C 5烷基氨基-C 1 -C 5烷基; 氨基二-N-C1-C5alkylamino-C1-C5烷基; C1--C 5烷氧基，C1-C5烷基; R2是C2-C20烷基; 羟基C1-C20烷基; 苯基; 苯基-C 1 -C 5烷基; 苯基-C 1 -C 5烷氧基; 单或二-N-C 1 -C 5烷基氨基-C 1 -C 5烷基; 氨基二-N-C1-C5alkylamino-C1-C5烷基; 或杂芳基-C 1 -C 5烷基; 或者R1和R2与键合氮原子一起形成5-至7-元单环杂环; 被描述。它们适用于抗菌处理的表面，特别是抗革兰氏阳性和革兰氏阴性细菌的抗微生物活性成分。

4. 发明申请

WO2003078367A2 BENZYL ALCOHOL DERIVATIVES 审中-公开
标题翻译： BENZYL酒精衍生物
公开(公告)号：WO2003078367A2
公开(公告)日：2003-09-25
申请号：PCT/EP2003/002618
申请日：2003-03-13
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , HÖLZL, Werner , KOPPOLD, Jürgen , MARQUAIS-BIENEWALD, Sophie , PREUSS, Andrea
发明人： HÖLZL, Werner , KOPPOLD, Jürgen , MARQUAIS-BIENEWALD, Sophie , PREUSS, Andrea
IPC分类号： C07C43/23
CPC分类号： A61Q17/005 , A01N31/14 , A01N31/16 , A01N55/00 , A61K8/34 , A61Q5/00 , A61Q11/00 , A61Q15/00 , C07C43/23 , C07C43/253 , C07F7/0818
摘要： The use of benzyl alcohol derivatives of the formula CH2OH in which R,, R2, R3, n and m have the meanings given in claim 1, as microbicidal active substances is described. The compounds exhibit a marked effect against pathogenic Gram-positive and Gramnegative bacteria. They are therefore suitable for the antimicrobial treatment, in particular preservation and disinfection, of surfaces.
摘要翻译：描述了其中R 1，R 2，R 3，n和m具有权利要求1中给出的含义的式CH 2 OH的苄醇衍生物作为杀微生物活性物质。该化合物对致病革兰氏阳性和革兰氏阴性细菌表现出显着的作用。因此，它们适用于表面的抗菌处理，特别是保存和消毒。

5. 发明申请

WO2005012235A1 3-ARYL-2-CYANO-3-HYDROXY-ACRYLIC ACID DERIVATIVES 审中-公开
标题翻译： 3-亚甲基-2-氰基-3-羟基 - 丙烯酸衍生物
公开(公告)号：WO2005012235A1
公开(公告)日：2005-02-10
申请号：PCT/EP2004/051533
申请日：2004-07-19
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , RELE, Dinesh Narendra , BHATTI, Harjinder Singh , HÖLZL, Werner , MARQUAIS-BIENEWALD, Sophie , MATHIAS, Errol Vincent , PREUSS, Andrea , WAGNER, Barbara
发明人： RELE, Dinesh Narendra , BHATTI, Harjinder Singh , HÖLZL, Werner , MARQUAIS-BIENEWALD, Sophie , MATHIAS, Errol Vincent , PREUSS, Andrea , WAGNER, Barbara
IPC分类号： C07C255/41
CPC分类号： C07C255/41 , A61K8/40 , A61L2/16 , A61Q15/00 , C11D3/26 , C11D7/32 , D06M13/1845 , Y10T442/2525
摘要： Disclosed are 3-aryl-2-cyano-3-hydroxy-acrylic acid derivates of formula(1a) (1b) or (1c) wherein R 1 is hydrogen, C 1 -C 20 alkyl; C 1 -C 20 alkoxy; CF 3 ; C 6 -C 10 aryl; or a radical of formula (1 a) and R 2 is hydrogen; or C 1 -C 20 alkyl. The compounds are used as antimicrobial actives for the treatment of surfaces.
摘要翻译：公开了式（1a）（1b）或（1c）的3-芳基-2-氰基-3-羟基 - 丙烯酸衍生物，其中R 1是氢，C 1 -C 20烷基; C1-C20alkoxy; CF3; C6-C10芳基; 或式（1a）和R2的基团是氢; 或C 1 -C 20烷基。这些化合物用作治疗表面的抗微生物活性物质。

6. 发明申请

WO2003078367A3 BENZYL ALCOHOL DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS 审中-公开
公开(公告)号：WO2003078367A3
公开(公告)日：2003-09-25
申请号：PCT/EP2003/002618
申请日：2003-03-13
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , HÖLZL, Werner , KOPPOLD, Jürgen , MARQUAIS-BIENEWALD, Sophie , PREUSS, Andrea
发明人： HÖLZL, Werner , KOPPOLD, Jürgen , MARQUAIS-BIENEWALD, Sophie , PREUSS, Andrea
IPC分类号： C07C43/23
摘要： The use of benzyl alcohol derivatives of the formula CH2OH in which R,, R2, R3, n and m have the meanings given in claim 1, as microbicidal active substances is described. The compounds exhibit a marked effect against pathogenic Gram-positive and Gramnegative bacteria. They are therefore suitable for the antimicrobial treatment, in particular preservation and disinfection, of surfaces.

7. 发明申请

WO2007085552A3 POLYMERIC ANTI-MICROBIAL AGENTS 审中-公开
公开(公告)号：WO2007085552A3
公开(公告)日：2007-08-02
申请号：PCT/EP2007/050420
申请日：2007-01-17
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , HUANG, Xinyu , DEISENROTH, Ted , PREUSS, Andrea , MARQUAIS-BIENEWALD, Sophie , JENNINGS, John , HENDRICKS-GUY, Carmen
发明人： HUANG, Xinyu , DEISENROTH, Ted , PREUSS, Andrea , MARQUAIS-BIENEWALD, Sophie , JENNINGS, John , HENDRICKS-GUY, Carmen
IPC分类号： C08G73/02 , C08L79/02 , A01N47/44
摘要： Polymeric anti-microbial agents produced by substituting the nitrogen atoms in the backbone of ethenimine polymers are provided. The agents are believed to have low human toxicity while being effective against a variety of pathogens and are useful in applications involving human contact, such as cosmetics, hair care products and textiles, as well as in applications with much less human contact, such as coatings.

8. 发明申请

WO2008009579A1 POLYMERIC HAIR DYES 审中-公开
标题翻译：聚合物染发剂
公开(公告)号：WO2008009579A1
公开(公告)日：2008-01-24
申请号：PCT/EP2007/056945
申请日：2007-07-09
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , MARQUAIS-BIENEWALD, Sophie , WALLQUIST, Olof , CREMER, Christian , FRÖHLING, Beate , MÖCK, Andreas
发明人： MARQUAIS-BIENEWALD, Sophie , WALLQUIST, Olof , CREMER, Christian , FRÖHLING, Beate , MÖCK, Andreas
IPC分类号： C09B69/10 , A61K8/72
CPC分类号： A61K8/84 , A61K8/8152 , A61K8/8158 , A61K8/86 , A61K8/898 , A61K2800/43 , A61K2800/5426 , A61K2800/57 , A61K2800/594 , A61Q5/02 , A61Q5/065 , A61Q5/12 , C09B69/105 , C09B69/106 , C09B69/107 , C09B69/109
摘要： Disclosed are polymeric dyes of formula (1a); (1b); or (1c); wherein A and B, independently from each other represent a polymer backbone; X 1 and X 2 independently from each other are a linkage group selected from -C 1 -C 10 alkylene-; -C 2 -C 12 alkenylene-; -C 5 -C 10 cycloalkylene-; C 5 -C 10 arylene; -C 5 -C 10 arylene-(C 1 -C 10 alkylene)-; -C(O)-; -(CH 2 CH 2 -O) 1-5 -; -C(O)O-; -OCO-; -N(R 1 )-; -CON(R 1 )-; -(R 1 )NC(O)-; -0-; -S-; -S(O)-; -S(O) 2 -; -S(O) 2 -N(R 1 R 2 ); or the direct bond; R 1 and R 2 independently from each other are hydrogen; or unsubstituted or substituted, straight-chain or branched, monocyclic or polycyclic, interrupted or uninterrupted C 1 - C 14 alkyl; C 2 -C 14 alkenyl; C 6 -C 10 aryl; C 6 -C 10 aryl-C 1 -C 10 alkyl; or C 5 -C 10 alky(C 5 -C 10 aryl); Y 1 and Y 2 independently from each other are a residue of an organic dye; or hydrogen; wherein at least one of Y 1 and Y 2 is a residue of an organic dye; An 1 , An 2 and An 3 , independently from each other are an anion; a and b independently from each other are a number from 1 to 3; m is a number from O to 1000; n is a number from O to 1000; and p is a number from 1 to 1000; wherein the sum of m + n + p ≥ 3.
摘要翻译：公开了式（1a）的聚合染料; （1B）; 或（1c）; 其中A和B彼此独立地表示聚合物主链; X 1和X 2彼此独立地是选自-C 1 -C 10亚烷基的连接基团 - ; -C _{2 -C _{12 烯基 - ; -C _{5 -C _{10 环亚烷基; ç_{5 -C _{10 亚芳基; -C _{5 -C _{10 亚芳基 - （C _{1 -C _{10 亚烷基） - ; -C（O） - ; - （CH _{2 CH _{2 -O）_{1-5 - ; -C（O）O-; -OCO-; -N（R _{1 ） - ; -CON（R _{1 ） - ; - （R _{1 ）NC（O） - ; -0-; -S-; -所以）-; -S（O）_{2 - ; -S（O）_{2 -N（R _{1 - [R _{2 ）; 或直接债券; R 1和R 2彼此独立地是氢; 或未取代或取代的直链或支链单环或多环，间断或不间断C 1 -C 14烷基; ç_{2 -C _{14 烯基; ç_{6 -C _{10 芳基; ç_{6 -C _{10 芳基-C _{1 -C _{10 烷基; 或C 5 -C 10烷基（C 5 -C 10芳基）;或C 5 -C 10烷基（C 5 -C 10 - 芳基）; Y 1和Y 2彼此独立地是有机染料的残基; 或氢; 其中Y 1和Y 2 2中的至少一个是有机染料的残基; 1个，2个和3个独立地是阴离子; a和b彼此独立，为1-3; m是从0到1000的数字; n是从0到1000的数字; p是从1到1000的数字; 其中m + n + p = 3的和。}}}}}}}}}}}}}}}}}}}}}}}}}}}}

9. 发明申请

WO2008006744A3 POLYSILOXANE ANTIMICROBIALS 审中-公开
公开(公告)号：WO2008006744A3
公开(公告)日：2008-01-17
申请号：PCT/EP2007/056703
申请日：2007-07-04
申请人： CIBA HOLDING INC. , MARQUAIS-BIENEWALD, Sophie , WALLQUIST, Olof , PREUSS, Andrea , ELDER, Stewart Todd
发明人： MARQUAIS-BIENEWALD, Sophie , WALLQUIST, Olof , PREUSS, Andrea , ELDER, Stewart Todd
IPC分类号： A01N55/10 , A01P1/00 , C07F7/08 , C08G77/38 , C08G77/388
摘要： Disclosed are oligo- or polysiloxanes, which are characterized by containing at least 3, for example 4 - 3000, Si atoms in the main chain, and wherein at least one thereof is contained in a moiety of the formula (I) whose open bond of the O atom is linked to another Si atom of the oligo- or polysiloxane main chain, and whose open bond of the Si atom is linked either to another O atom of the oligo- or polysiloxane main chain or to R' 1, where R 1 and R' 1 independently are C 1 -C 10 alkyl, R 2 and R 3 independently are C 1 -C 18 alkylene, X is a divalent spacer group selected from O, NR 4, N(COR' 5 ), CONR' 4, OCONR' 4; .Y is selected from OCOR 5, NHCOR 5, NHR 4 , COOR 5, CONHR 4, NR' 4 R 4; R 4 is selected from C 6 -C 18 organic residues containing at least one aryl moiety; R' 4 is as defined for R 4; or is selected from H, C 1 -C 20 alkyl, C 7 -C 20 phenylalkyl, C 4 - C 12 cycloalkyl; R 5 is R 7 -Z; R' 5 is as defined for R 5; or is selected from H, C 1 -C 20 alkyl, C 7 -C 20 phenylalkyl, C 4 - C 12 cycloalkyl; R 7 is C 1 -C 20 alkylene, which may be interrupted by phenylene, C 4 -C 12 cycloalkylene, O, NR' 4; or is unsubstituted or substituted phenylene or C 4 -C 12 cycloalkylene; Z is halogen or N+R 8 R 9 R 10; R 8 , R 9 and R 10 independently are selected from C 1 -C 20 alkyl, C 7 -C 20 phenylalkyl, C 4 - C 12 cycloalkyl, unsubstituted or substituted aryl; or 2 of R 8 , R 9 and R 10 are linked together to form a quaternized aliphatic, substituted or unsubstituted N-heterocyclic ring of 4-6 carbon atoms such as a piperidine ring; or all of R 8 , R 9 and R 10 are linked together to form, together with the nitrogen atom they are bonding to, a substituted or unsubstituted N-heterocyclic ring system of 4-7 carbon atoms. The novel compounds are effective as antimicrobials.

10. 发明申请

WO2012022709A1 DISULFIDE OR THIOL POLYMERIC HAIR DYES 审中-公开
标题翻译： DISOLFIDE或THIOL POLYMERIC HAIR DYES
公开(公告)号：WO2012022709A1
公开(公告)日：2012-02-23
申请号：PCT/EP2011/064022
申请日：2011-08-15
申请人： BASF SE , MARQUAIS-BIENEWALD, Sophie , CREMER, Christian , FRÖHLING, Beate
发明人： MARQUAIS-BIENEWALD, Sophie , CREMER, Christian , FRÖHLING, Beate
IPC分类号： C09B62/78 , C09B69/10 , A61Q5/10
CPC分类号： C09B67/0063 , A61K8/817 , A61K8/84 , A61K8/91 , A61Q5/10 , C09B62/78 , C09B69/101 , C09B69/106
摘要： The present invention relates to the reaction product of (A) a polymeric backbone with (B) A chromophore; and with (C) at least one sulfide containing compound. Very good dyeing results are obtained with this new technology.
摘要翻译：本发明涉及（A）聚合物主链与（B）A发色团的反应产物; 和（C）至少一种含硫化物的化合物。使用这种新技术可以获得非常好的染色结果。

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