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1. 发明申请

WO2012003140A2 IMPLANTABLE MEDICAL DEVICE AND CHARGING SYSTEM EMPLOYING ELECTRIC FIELDS 审中-公开
标题翻译：可植入医疗设备和充电电气系统的充电系统
公开(公告)号：WO2012003140A2
公开(公告)日：2012-01-05
申请号：PCT/US2011/041773
申请日：2011-06-24
申请人： BOSTON SCIENTIFIC NEUROMODULATION CORPORATION , CHEN, Joey , OZAWA, Robert , HYUN, Joonho , DRONOV, Vasily
发明人： CHEN, Joey , OZAWA, Robert , HYUN, Joonho , DRONOV, Vasily
IPC分类号： A61N1/378
CPC分类号： A61N1/37223 , A61N1/3787 , H01Q1/273 , H01Q9/42
摘要： An implantable medical device and external base station system are disclosed. The external base station can provide a passive electric field to power the implant, or to charge its battery. The base station may also power or charge using magnetic fields under certain circumstances. The Implantable medical device may comprise an implantable neurostimulator having a number of electrode leads extending from its body. One or more of the electrode leads can comprise the antenna for receiving the electric field from the base station, and resonance in that antenna can be rectified to provide the power for recharging the battery. Although the E-field provided by the base station does not provide as much power for recharging as does other traditional charging techniques (such as those using magnetic fields), it can occur passively and over longer distances to allow the patent's implant to be recharged when in relative proximity to the base station.
摘要翻译：公开了可植入医疗装置和外部基站系统。外部基站可以提供无源电场来为植入物供电，或为其电池充电。在某些情况下，基站也可以使用磁场进行供电或充电。植入式医疗装置可以包括具有从其主体延伸的多个电极引线的可植入神经刺激器。电极引线中的一个或多个可以包括用于从基站接收电场的天线，并且该天线中的谐振可被整流以提供用于为电池再充电的电力。虽然由基站提供的电场不像其他传统的充电技术（例如使用磁场的那些）那样提供充电的功率，但它可以被动地和超过更长的距离发生，以允许专利的植入物被充电，在相对靠近基站。

2. 发明申请

WO2012003131A2 CHARGING SYSTEM FOR AN IMPLANTABLE MEDICAL DEVICE EMPLOYING MAGNETIC AND ELECTRIC FIELDS 审中-公开
标题翻译：使用磁场和电场的可植入医疗装置的充电系统
公开(公告)号：WO2012003131A2
公开(公告)日：2012-01-05
申请号：PCT/US2011/041606
申请日：2011-06-23
申请人： BOSTON SCIENTIFIC NEUROMODULATION CORPORATION , CHEN, Joey , OZAWA, Robert , HYUN, Joonho , DRONOV, Vasily
发明人： CHEN, Joey , OZAWA, Robert , HYUN, Joonho , DRONOV, Vasily
IPC分类号： A61N1/378 , A61N1/372
CPC分类号： A61N1/37223 , A61N1/3787 , H01Q1/273 , H01Q9/42
摘要： A base station for passively recharging a battery in an implant without patient involvement is disclosed. The base station can be hand held or may comprise equipment configured to be placed at a fixed location, such as under a bed, on or next to a wall, etc. The base station can generate electric and magnetic fields (E- field and B-field) that couple with an antenna and a receiving coil within the implant to generate a charging current for charging the implant's battery. No handling or manipulation on part of the patient is necessary; the implant battery is passively charged whenever the patient is within range of either the magnetic or electric charging fields generated by base station. Charging using the B-field occurs when the IPG is at a relatively short distance from the base station, while charging using the E-field occurs at longer distances. Back telemetry from the implant can inform the base station whether B-field or E-field charging is indicated, and is preferred if possible for its ability to transfer higher amounts of power to the implant.
摘要翻译：公开了一种用于在植入物中无源地给电池充电而无需患者参与的基站。基站可以是手持式的，或者可以包括被配置为放置在固定位置处的设备，例如在床下面，墙上或旁边等。基站可以产生电场和磁场（E场和B场场），其与植入物内的天线和接收线圈耦合以生成用于给植入物的电池充电的充电电流。部分患者不需要操作或操作; 无论何时患者处于由基站产生的磁场或电荷场的范围内，植入物电池都被动充电。当IPG距离基站相对较短的距离时，使用B场进行充电，而使用电场进行充电的距离较远。来自种植体的背部遥测可以通知基站是否指示B场或电场充电，并且如果可能的话，由于其向植入物传递更大量的功率的能力是优选的。

3. 发明申请

WO2011063111A2 AN EFFICIENT EXTERNAL CHARGER FOR CHARGING A PLURALITY OF IMPLANTABLE MEDICAL DEVICES 审中-公开
标题翻译：有效的外部充电器，用于充电多种可植入医疗器械
公开(公告)号：WO2011063111A2
公开(公告)日：2011-05-26
申请号：PCT/US2010/057212
申请日：2010-11-18
申请人： BOSTON SCIENTIFIC NEUROMODULATION CORPORATION , CARBUNARU, Rafael , PARRAMON, Jordi , OZAWA, Robert , SHI, Jess , CHEN, Joey , RAHMAN, Mizanur
发明人： CARBUNARU, Rafael , PARRAMON, Jordi , OZAWA, Robert , SHI, Jess , CHEN, Joey , RAHMAN, Mizanur
IPC分类号： A61N1/378
CPC分类号： A61N1/3787 , A61N1/37223 , A61N1/37288
摘要： An improved external charger for a battery in an implantable medical device (implant), and technique for charging batteries in multiple implants using such improved external charger, is disclosed. During charging, values for a parameter measured in the implants are reported from the implants to the external charger. The external charger infers from the magnitudes of the parameters which of the implants has the highest and lowest coupling to the external charger, and so designates those implants as "hot" and "cold." The intensity of the magnetic charging field is optimized for the cold implant consistent with the simulation to ensure that that the cold implant is charged with a maximum (fastest) battery charging current. The duty cycle of the magnetic charging field is also optimized for the hot implant consistent with the simulation to ensure that the hot implant does not exceed the power dissipation limit. As a result, charging is optimized to be fast for all of the implants, while still safe from a tissue heating perspective.
摘要翻译：公开了一种用于可植入医疗装置（植入物）中的电池的改进的外部充电器，以及使用这种改进的外部充电器为多个植入物中的电池充电的技术。在充电期间，在植入物中测量的参数的值从植入物报告给外部充电器。外部充电器从参数的大小推断出植入物具有最高和最低耦合到外部充电器的参数，因此将这些植入物称为“热”和“冷”。对于与模拟一致的冷植入物，磁充电场的强度被优化，以确保冷植入物以最大（最快）的电池充电电流充电。对于与模拟一致的热注入，磁充电场的占空比也被优化，以确保热植入不超过功率耗散极限。因此，对于所有植入物，充电被优化为快速，同时从组织加热的角度来看仍然是安全的。

4. 发明申请

WO2013012487A1 BATTERY MANAGEMENT FOR AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：可植入医疗器械的电池管理
公开(公告)号：WO2013012487A1
公开(公告)日：2013-01-24
申请号：PCT/US2012/041551
申请日：2012-06-08
申请人： BOSTON SCIENTIFIC NEUROMODULATION CORPORATION , PARRAMON, Jordi , MARNFELDT, Goran, N. , OZAWA, Robert , FELDMAN, Emanuel , PETERSON, Dave , HE, Yuping
发明人： PARRAMON, Jordi , MARNFELDT, Goran, N. , OZAWA, Robert , FELDMAN, Emanuel , PETERSON, Dave , HE, Yuping
IPC分类号： A61N1/378
CPC分类号： A61N1/3787 , A61N1/08
摘要： Battery management circuitry for an implantable medical device such as an implantable neurostimulator is described. The circuitry has a T-shape with respect to the battery terminal, with charging circuitry coupled between rectifier circuitry and the battery terminal on one side of the T, and load isolation circuitry coupled between the load and the battery terminal on the other side. The load isolation circuitry can comprise two switches wired in parallel. An undervoltage fault condition opens both switches to isolate the battery terminal from the load to prevent further dissipation of the battery. Other fault conditions will open only one the switches leaving the other closed to allow for reduced power to the load to continue implant operations albeit at safer low-power levels. The battery management circuitry can be fixed in a particular location on an integrated circuit which also includes for example the stimulation circuitry for the electrodes.
摘要翻译：描述了诸如可植入神经刺激器的可植入医疗装置的电池管理电路。电路相对于电池端子具有T形，充电电路耦合在整流器电路和T的一侧上的电池端子之间，负载隔离电路耦合在另一侧的负载和电池端子之间。负载隔离电路可以包括并联的两个开关。欠压故障条件打开两个开关以将电池端子与负载隔离，以防止电池进一步耗散。其他故障条件将只打开一个开关，使另一个闭合，以允许减小负载的电力，以继续进行种植体操作，尽管处于更安全的低功率水平。电池管理电路可以固定在集成电路的特定位置，该集成电路还包括例如用于电极的刺激电路。

5. 发明申请

WO2011119352A1 INDUCTIVE CHARGER WITH MAGNETIC SHIELDING 审中-公开
标题翻译：电磁屏蔽电感充电器
公开(公告)号：WO2011119352A1
公开(公告)日：2011-09-29
申请号：PCT/US2011/028071
申请日：2011-03-11
申请人： BOSTON SCIENTIFIC NEUROMODULATION , CHEN, Joey , OZAWA, Robert , AGHASSIAN, Daniel
发明人： CHEN, Joey , OZAWA, Robert , AGHASSIAN, Daniel
IPC分类号： A61N1/378 , A61N1/05 , A61N1/36
CPC分类号： A61N1/3758 , A61N1/3787 , H01F27/365 , H01F38/14 , H02J7/025 , H02J50/10 , H02J50/70
摘要： To recharge an implanted medical device, an external device, typically in the form of an inductive charger, is placed over the implant to provide for transcutaneous energy transfer. The external charging device can be powered by a rechargeable battery. Since the battery is in close proximity to the charge coil, the large magnetic field produced by the charge coil induces eddy currents that flow on the battery's metallic case, often resulting in undesirable heating of the battery and reduced efficiency of the charger. This disclosure provides a means of shielding the battery from the magnetic field to reduce eddy current heating, thereby increasing efficiency. In one embodiment, the magnetic shield consists of one or more thin ferrite plates. The use of a ferrite shield allows the battery to be placed directly over the charge coil as opposed to outside the extent of the charge coil.
摘要翻译：为了对植入的医疗装置充电，通常以感应充电器的形式的外部装置放置在植入物上以提供经皮能量转移。外部充电装置可以由可充电电池供电。由于电池靠近充电线圈，由充电线圈产生的大磁场引起在电池金属壳体上流动的涡流，经常导致电池的不期望的加热并降低充电器的效率。本公开提供了一种屏蔽电池免受磁场的影响，以减少涡流加热，从而提高效率。在一个实施例中，磁屏蔽由一个或多个薄铁氧体板组成。铁氧体屏蔽的使用允许电池直接放置在充电线圈上方，而不是在充电线圈的范围之外。

6. 发明申请

WO2013055527A1 CLOSED LOOP CHARGER FOR AN IMPLANTABLE MEDICAL DEVICE SYSTEM EMPLOYING REFLECTED IMPEDANCE MODULATION 审中-公开
标题翻译：用于采用反射阻抗调制的可植入医疗器械系统的闭环式充电器
公开(公告)号：WO2013055527A1
公开(公告)日：2013-04-18
申请号：PCT/US2012/057593
申请日：2012-09-27
申请人： BOSTON SCIENTIFIC NEUROMODULATION CORPORATION
发明人： OZAWA, Robert , AGHASSIAN, Daniel
IPC分类号： A61N1/378
CPC分类号： A61N1/3787 , A61N1/37252
摘要： The disclosed system for providing closed loop charging between an external charger and an implantable medical device such as an IPG involves the use of reflected impedance modulation, i.e., by measuring at the external charger reflections arising from modulating the impedance of the charging coil in the IPG. During charging, the charging coil in the IPG is periodically pulsed to modulate its impedance. The magnitude of the change in the coil voltage produced at the external charger ΔV as a result of these pulses is assessed and is used by the controller circuitry in the external charger as indicative of the coupling between the external charger and the IPG. The external charger adjusts its output power (e.g., Icharge) in accordance with the magnitude of ΔV, thus achieving closed loop charging without the need of telemetering coupling parameters from the IPG.
摘要翻译：所公开的用于在外部充电器和诸如IPG的可植入医疗设备之间提供闭环充电的系统涉及使用反射阻抗调制，即通过在外部充电器处测量在IPG中调制充电线圈的阻抗而产生的反射。在充电期间，IPG中的充电线圈被周期性地脉冲以调制其阻抗。评估由外部充电器引起的外部充电器DeltaV产生的线圈电压的变化幅度，并由外部充电器中的控制器电路用来表示外部充电器与IPG之间的耦合。外部充电器根据DeltaV的大小来调节其输出功率（例如，Icharge），从而实现闭环充电，而不需要来自IPG的遥测耦合参数。

7. 发明申请

WO2014175954A1 HEATING CONTROL FOR AN INDUCTIVE EXTERNAL CHARGER FOR AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于可植入医疗器械的电感式外部充电器的加热控制
公开(公告)号：WO2014175954A1
公开(公告)日：2014-10-30
申请号：PCT/US2014/018058
申请日：2014-02-24
申请人： BOSTON SCIENTIFIC NEUROMODULATION CORPORATION
发明人： OZAWA, Robert
IPC分类号： A61N1/378
CPC分类号： A61N1/3787 , A61N1/36125
摘要： The disclosed technique for charging a battery in an implantable medical device using an external charger indirectly determines the total power dissipated as heat in the IPG (P_IPG) by accounting for the various powers in the external charger/IPG system which are either known or can be measured, such as the input power provided to the amplifier that drives the coil in the external charger (Psys), the power stored in the IPG's battery (Pstored), and the power dissipated in the external charger's charging coil as heat (P_EC) (which is measured). Determining P_IPG at the external charger in this manner allows the heat flux from the IPG to be calculated (F_IPG), and compared to a safe heat flux limit (F_IPG') to allow for adjustment to the power of the magnetic charging field in a closed loop fashion.
摘要翻译：所公开的使用外部充电器对可植入医疗装置中的电池进行充电的技术间接地通过考虑外部充电器/ IPG系统中已知的或可能的外部充电器/ IPG系统中的各种功率间接地确定作为IPG（P_IPG）中的热量的总功率测量，例如提供给驱动外部充电器（Psys）中的线圈的放大器的输入功率，存储在IPG的电池（Pstored）中的电力）和外部充电器充电线圈中作为热量（P_EC）（P_EC）测量）。以这种方式确定外部充电器上的P_IPG允许计算来自IPG的热通量（F_IPG），并将其与安全的热通量极限（F_IPG'）进行比较，以允许在关闭状态下调节充磁场的功率循环时尚。

8. 发明申请

WO2013055526A1 CHARGER ALIGNMENT IN AN IMPLANTABLE MEDICAL DEVICE SYSTEM EMPLOYING REFLECTED IMPEDANCE MODULATION 审中-公开
标题翻译：采用反射阻抗调制的可植入医疗器械系统中的充电对齐
公开(公告)号：WO2013055526A1
公开(公告)日：2013-04-18
申请号：PCT/US2012/057582
申请日：2012-09-27
申请人： BOSTON SCIENTIFIC NEUROMODULATION CORPORATION
发明人： OZAWA, Robert , AGHASSIAN, Daniel
IPC分类号： A61N1/378
CPC分类号： A61N1/3787 , A61F2250/0001 , A61N1/08 , A61N1/37252 , H02J5/005 , H02J7/025
摘要： The disclosed means of determining alignment between an external charger and an implantable medical device (IMD) involves the use of reflected impedance modulation, i.e., by measuring at the external charger reflections arising from modulating the impedance of the charging coil in the IMD. During charging, the charging coil in the IMD is pulsed to modulate its impedance. The difference in the coil voltage (ΔV) produced at the external charger as a result of these pulses is assessed and is used by the external charger to indicate coupling. If the magnitude of ΔY is above a threshold, the external charger considers the coupling to the IMD to be adequate, and an alignment indicator in the external charger is controlled accordingly. The magnitude of Vcoil can be assessed in addition to ΔV to determine alignment with the IMD with improved precision, and/or to further define a high quality alignment condition.
摘要翻译：所公开的确定外部充电器和可植入医疗装置（IMD）之间的对准的方法涉及使用反射阻抗调制，即通过在调制IMD中的充电线圈的阻抗而产生的外部充电器反射下测量。在充电期间，IMD中的充电线圈被脉冲以调制其阻抗。评估由外部充电器产生的线圈电压（DeltaV）与这些脉冲之间的差异，并由外部充电器用于指示耦合。如果DeltaY的大小超过阈值，外部充电器认为与IMD的耦合足够，并且相应地控制外部充电器中的对准指示器。除了DeltaV之外，还可以评估Vcoil的幅度，以确定与IMD的准确度的精确度，和/或进一步确定高质量的对准条件。

9. 发明申请

WO2013062712A1 COMMUNICATION AND CHARGING CIRCUITRY FOR A SINGLE-COIL IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：单线圈可植入器件的通信和充电电路
公开(公告)号：WO2013062712A1
公开(公告)日：2013-05-02
申请号：PCT/US2012/057585
申请日：2012-09-27
申请人： BOSTON SCIENTIFIC NEUROMODULATION CORPORATION
发明人： FELDMAN, Emanuel , DRONOV, Vasily , PARRAMON, Jordi , OZAWA, Robert , RAHMAN, Mizanur
IPC分类号： A61N1/378 , A61N1/36
CPC分类号： H01F38/14 , A61N1/36 , A61N1/37223 , A61N1/3787 , H02J50/12 , H04Q9/12
摘要： Improved communication and charging circuitry for an implantable medical device is described having a single coil for receiving charging energy and for data telemetry. The circuitry removes from the AC side of the circuit a tuning capacitor and switch traditionally used to tune the tank circuitry to different frequencies for telemetry and charging. As such, the tank circuitry is simplified and contains no switchable components that can be difficult to implement. A switch is serially connected to the storage capacitor on the DC side of the circuit, which essentially takes the place of the switch of the prior art by tuning the circuit for telemetry or charging. During telemetry, the switch is opened, thus disconnecting the storage capacitor from the tank circuit, and alleviating concerns that this capacitor will couple to the tank circuit and interfere with telemetry operations. During charging, the switch is closed, which allows the storage capacitor to couple to the tank circuitry through the rectifier during some portions of the tank circuitry's resonance.
摘要翻译：描述了用于可植入医疗装置的改进的通信和充电电路，其具有用于接收充电能量和用于数据遥测的单个线圈。该电路从电路的AC侧消除了调谐电容器和传统上用于将电路调谐到不同频率的开关，用于遥测和充电。因此，容器电路被简化并且不包含难以实现的可切换部件。开关串联连接到电路的直流侧的存储电容器，其基本上取代了现有技术的开关，通过调谐电路进行遥测或充电。在遥测期间，开关打开，从而将储存电容器与储能电路断开，并减轻该电容器将耦合到储能电路并干扰遥测操作的担忧。在充电期间，开关闭合，这允许存储电容器在储罐电路的共振的某些部分期间通过整流器耦合到储能电路。

10. 发明授权

EP2766091B1 CLOSED LOOP CHARGER FOR AN IMPLANTABLE MEDICAL DEVICE SYSTEM EMPLOYING REFLECTED IMPEDANCE MODULATION 有权
标题翻译：与医疗器械闭环植入了一个反射阻抗调制LOADER
公开(公告)号：EP2766091B1
公开(公告)日：2016-12-21
申请号：EP12778540.0
申请日：2012-09-27
申请人： Boston Scientific Neuromodulation Corporation
发明人： OZAWA, Robert , AGHASSIAN, Daniel
IPC分类号： A61N1/378 , A61N1/372
CPC分类号： A61N1/3787 , A61N1/37252
摘要： The disclosed system for providing closed loop charging between an external charger and an implantable medical device such as an IPG involves the use of reflected impedance modulation, i.e., by measuring at the external charger reflections arising from modulating the impedance of the charging coil in the IPG. During charging, the charging coil in the IPG is periodically pulsed to modulate its impedance. The magnitude of the change in the coil voltage produced at the external charger &Dgr;V as a result of these pulses is assessed and is used by the controller circuitry in the external charger as indicative of the coupling between the external charger and the IPG. The external charger adjusts its output power (e.g., Icharge) in accordance with the magnitude of &Dgr;V, thus achieving closed loop charging without the need of telemetering coupling parameters from the IPG.

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