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1. 发明申请

WO0136606A3 PROTOPORPHYRINOGEN IX OXIDASE AND THE USE THEREOF 审中-公开
标题翻译：原卟啉原Ⅸ氧化酶及其用途
公开(公告)号：WO0136606A3
公开(公告)日：2001-11-15
申请号：PCT/EP0011100
申请日：2000-11-10
申请人： BASF PLANT SCIENCE GMBH , SCHIFFER HELMUT , LERCHL JENS , GRIMM BERNHARD , LERMONTOVA INNA , VORONETSKAJA VALERIA
发明人： SCHIFFER HELMUT , LERCHL JENS , GRIMM BERNHARD , LERMONTOVA INNA , VORONETSKAJA VALERIA
IPC分类号： C12N9/02 , C12N15/82 , A01H1/00 , C07K14/415
CPC分类号： C12N9/001 , C12N15/8209 , C12N15/8243 , C12N15/8274
摘要： The present invention relates to DNA sequences coding for a polypeptide that is resistant against peroxidising inhibitors of the protoporphyrinogen IX oxidase.
摘要翻译：本发明涉及编码用于要在过氧化Protoporphrinogen-IX氧化酶抑制剂抗性的多肽的DNA序列。

2. 发明申请

WO0144476A3 Moss genes from physcomitrella patens encoding proteins involved in the synthesis of carbohydrates 审中-公开
标题翻译：编码参与碳水化合物合成的蛋白质的小麦藓的苔藓基因
公开(公告)号：WO0144476A3
公开(公告)日：2002-04-25
申请号：PCT/EP0012697
申请日：2000-12-14
申请人： LERCHL JENS , RENZ ANDREAS , EHRHARDT THOMAS , REINDL ANDREAS , CIRPUS PETRA , BISCHOFF FRIEDRICH , FRANK MARKUS , FREUND ANNETTE , DUWENIG ELKE , SCHMIDT RALF-MICHAEL , RESKI RALF , BASF PLANT SCIENCE GMBH
发明人： LERCHL JENS , RENZ ANDREAS , EHRHARDT THOMAS , REINDL ANDREAS , CIRPUS PETRA , BISCHOFF FRIEDRICH , FRANK MARKUS , FREUND ANNETTE , DUWENIG ELKE , SCHMIDT RALF-MICHAEL , RESKI RALF
IPC分类号： C07K14/415 , C12N9/00 , C12N15/29 , C07K16/16 , C07K16/40 , C12P19/00 , G01N33/573 , G01N33/68
CPC分类号： C12N9/00 , C07K14/415
摘要： Isolated nucleic acid molecules, designated CMRP nucleic acid molecules, which encode novel CMRPs from Physcomitrella patens are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing CMRP nucleic acid molecules, and host cells and organisms into which the expression vectors have been introduced. The invention still further provides isolated CMRPs, mutated CMRPs, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from transformed cells based on genetic engineering of CMRP genes in this organism.
摘要翻译：描述了编码来自小立碗藓的新型CMRP的分离的核酸分子，命名为CMRP核酸分子。本发明还提供反义核酸分子，含有CMRP核酸分子的重组表达载体，以及引入表达载体的宿主细胞和生物体。本发明还进一步提供了基于该生物体中CMRP基因的遗传工程的分离的CMRP，突变CMRPs，融合蛋白，抗原肽和用于从转化细胞产生所需化合物的方法。

3. 发明申请

WO0144276A2 MOSS GENES FROM PHYSCOMITRELLA PATENS ENCODING PROTEINS INVOLVED IN THE SYNTHESIS OF TOCOPHEROLS AND CAROTENOIDS 审中-公开
标题翻译：来自PHYSCOMITRELLA PATES的MOSS基因编码参与合成植物油和卡诺菌素的蛋白质
公开(公告)号：WO0144276A2
公开(公告)日：2001-06-21
申请号：PCT/EP0012698
申请日：2000-12-14
申请人： BASF PLANT SCIENCE GMBH , LERCHL JENS , RENZ ANDREAS , EHRHARDT THOMAS , REINDL ANDREAS , CIRPUS PETRA , BISCHOFF FRIEDRICH , FRANK MARKUS , FREUND ANNETTE , DUWENIG ELKE , SCHMIDT RALF MICHAEL , RESKI RALF , BADUR RALF
发明人： LERCHL JENS , RENZ ANDREAS , EHRHARDT THOMAS , REINDL ANDREAS , CIRPUS PETRA , BISCHOFF FRIEDRICH , FRANK MARKUS , FREUND ANNETTE , DUWENIG ELKE , SCHMIDT RALF-MICHAEL , RESKI RALF , BADUR RALF
IPC分类号： C12N9/10 , C12N15/52 , C12N15/82 , C07K14/00
CPC分类号： C12N9/1007 , C12N15/52 , C12N15/8243 , C12N15/825
摘要： Isolated nucleic acid molecules, designated TCMRP nucleic acid molecules, which encode novel TCMRPs from e.g. Physcomitrella patens are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing TCMRP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated TCMRPs, mutated TCMRPs, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from transformed cells, organisms or plants based on genetic engineering of TCMRP genes in these organisms.
摘要翻译：分离的核酸分子，命名为TCMRP核酸分子，其编码来自例如新鲜的TCMRP。描述了小立碗藓。本发明还提供反义核酸分子，含有TCMRP核酸分子的重组表达载体，以及引入了表达载体的宿主细胞。本发明还进一步提供了分离的TCMRP，突变的TCMRP，融合蛋白，抗原肽和基于这些生物体中TCMRP基因的遗传工程改进从转化细胞，生物体或植物生产所需化合物的方法。

4. 发明申请

WO02057465A3 METHOD FOR PRODUCING POLYUNSATURATED FATTY ACIDS, NOVEL BIOSYNTHESIS GENES AND NOVEL PLANT EXPRESSION CONSTRUCTS 审中-公开
标题翻译：用于生产多不饱和脂肪酸，合成新的和新工厂的表达构建
公开(公告)号：WO02057465A3
公开(公告)日：2003-06-12
申请号：PCT/EP0200462
申请日：2002-01-18
申请人： BASF PLANT SCIENCE GMBH , LERCHL JENS , RENZ ANDREAS , HEINZ ERNST , DOMERGUE FREDERIC , ZAEHRINGER ULRICH
发明人： LERCHL JENS , RENZ ANDREAS , HEINZ ERNST , DOMERGUE FREDERIC , ZAEHRINGER ULRICH
IPC分类号： A01H5/00 , A01K67/027 , A23D9/007 , A23L1/30 , A61K8/30 , A61K8/34 , A61K8/37 , A61K31/201 , A61K31/202 , A61K31/231 , A61K31/232 , A61K31/7088 , A61K36/00 , A61K39/395 , A61K45/00 , A61P3/06 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/02 , C12N15/09 , C12N15/53 , C12N15/82 , C12P7/64 , C12Q1/02 , C12Q1/26 , G01N33/15 , G01N33/50 , C11B1/00 , C12N15/11 , C12P7/62 , C12Q1/68 , G01N33/573
CPC分类号： C12N9/0083 , C12N15/8247 , C12P7/6427 , C12P7/6472
摘要： The invention relates to a method for producing unsaturated fatty acids comprising at least two double bonds, and a method for producing triglycerides having an increased content of polyunsaturated fatty acids comprising at least two double bonds. The invention also relates to the advantageous use of the nucleic acid sequences of SEQ ID NO: 1, SEQ ID NO: 3, SEQ ID NO: 5, SEQ ID NO: 9, SEQ ID NO: 11 or SEQ ID NO: 18 in the inventive methods, and for producing a transgenic organism, preferably a transgenic plant or a transgenic micro-organism having an increased content of fatty acids, oils or lipids containing unsaturated C18, C20, or C22 fatty acids. The invention further relates to novel desaturases comprising the sequences of SEQ ID NO. 1, SEQ ID NO: 3, SEQ ID NO: 5 and SEQ ID NO: 11, or the homologues, derivatives or analogues thereof, and gene constructs comprising said genes or the homologues, derivatives or analogues thereof, in addition to the use of the same, either alone or combined with biosynthesis genes of polyunsaturated fatty acids, as advantageously represented in SEQ ID NO: 7 and SEQ ID NO: 9. Furthermore, the invention relates to isolated nucleic acid sequences, expression cassettes containing said nucleic acid sequences, vectors, and transgenic organisms containing at least one nucleic acid sequence or an expression cassette. The invention also relates to unsaturated fatty acids comprising at least two double bonds and triglycerides having an increased content of unsaturated fatty acids comprising at least two double bonds, and the use of the same. Finally, the invention relates to multi-expression cassettes for seed-specific expression, in addition to vectors or organisms comprising a desaturase gene, either alone or combined with other desaturases having the sequence of SEQ ID NO: 7 and/or elongase genes having the sequence of ID NO: 9 or the homologues, derivatives or analogues of the same, expressed by means of the above-mentioned expression cassettes.
摘要翻译：本发明涉及一种用于制备具有至少两个双键和/或用于生产甘油三酯的具有多不饱和脂肪酸与多不饱和脂肪酸具有至少两个双键的至少höhtem含量增加的内容的方法的不饱和脂肪酸的方法。本发明还涉及有利地使用的核酸序列的SEQ ID NO：1，SEQ ID NO：3，SEQ ID NO：5，SEQ ID NO：9，SEQ ID NO：11或SEQ ID NO：18中的过程和用于生产的转基因生物体，优选转基因植物或具有脂肪酸，油或脂类具有不饱和C18，C20，C22或脂肪酸含量增加的转基因微生物。本发明还涉及新的去饱和酶与序列SEQ ID号 1，SEQ ID NO：3，SEQ ID NO：5和SEQ ID NO：11或它的同系物，衍生物或它们的类似物，和包含所述基因的基因构建体或他们的同系物，衍生物或类似物，并单独或与生物合成基因组合使用它们polyungesätigter 脂肪酸，例如有利地在SEQ ID NO：9：7和SEQ ID NO。本发明还涉及分离的核酸序列; 表达盒包含Nukleinesäuresequenzen。载体，以及含有至少一种核酸序列或表达盒的转基因生物。本发明还涉及一种具有至少两个双键和具有具有至少两个双键和其用途的不饱和脂肪酸含量增加的甘油三酯不饱和脂肪酸。本发明还涉及用于种子特异性表达，其包括单独或与具有SEQ ID NO：1的序列的其它去饱和酶组合的去饱和酶基因的多表达盒和载体或生物体：7和/或延长酶基因与去SEQ ID NO：9或它的同系物，衍生物或类似物包括使用vesagter的表达盒。

5. 发明申请

WO02057464A3 METHOD FOR THE EXPRESSION OF BIOSYNTHETIC GENES IN PLANT SEEDS USING MULTIPLE EXPRESSION CONSTRUCTS 审中-公开
标题翻译：为了表达蔬菜种子的生物合成基因的方法是在使用多个表达构建
公开(公告)号：WO02057464A3
公开(公告)日：2003-02-27
申请号：PCT/EP0200461
申请日：2002-01-18
申请人： BASF PLANT SCIENCE GMBH , LERCHL JENS , DUWENIG ELKE , BISCHOFF FRIEDRICH , HEINZ ERNST , DREXLER HJOERDIS , SCHEFFLER JODI
发明人： LERCHL JENS , DUWENIG ELKE , BISCHOFF FRIEDRICH , HEINZ ERNST , DREXLER HJOERDIS , SCHEFFLER JODI
IPC分类号： C12N9/02 , C12N9/10 , C12N15/29 , C12N15/53 , C12N15/54 , C12N15/82 , A01H5/00 , C12N15/81 , C12P7/64
CPC分类号： C12N9/0083 , C12N9/1029 , C12N15/8247
摘要： The invention relates to expression cassettes, combinations thereof and vectors containing said expression cassettes, containing plant promoters with an expression specificity for plant seeds, in particular linseed and the use of said expression cassettes or vectors for the recombinant expression of heterologous genes in plants. The invention further relates to transgenic plants, transformed by means of said expression cassettes, or vectors, cultures, parts or transgenic propagations derived therefrom and the use of the above as foodstuff, animal feedstuff, seedstuff, pharmaceuticals, fine chemicals or industrial raw material.
摘要翻译：本发明涉及一种表达盒，其组合以及含有包含植物启动子用表达特异性植物种子，特别是亚麻子和异源基因在植物中的重组表达使用这些表达盒或载体的表达盒的载体。这些表达盒或转化的培养物从，部件或转基因繁殖材料衍生的转基因植物的载体，并且其用作食品，饲料或种子，医药品，精细化学品或工业原料本发明进一步涉及。

6. 发明申请

WO9810074A2 ADENYLOSUCCINATE SYNTHETASE 审中-公开
标题翻译：腺苷酸合成酶
公开(公告)号：WO9810074A2
公开(公告)日：1998-03-12
申请号：PCT/EP9704812
申请日：1997-09-04
申请人： BASF AG , LERCHL JENS , SCHMIDT RALF MICHAEL , SCHIFFER HELMUT , SONNEWALD UWE , BADUR RALF
发明人： LERCHL JENS , SCHMIDT RALF-MICHAEL , SCHIFFER HELMUT , SONNEWALD UWE , BADUR RALF
IPC分类号： A01H5/00 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/10 , C12N15/09 , C12N15/82 , C12R1/125 , C12N15/52
CPC分类号： C12N9/93 , C12N15/8274
摘要： Expression cartridges are disclosed which confer to plants, plant cells, tissues or parts a resistance against inhibitors of the vegetable adenylosuccinate synthetases. Also disclosed is the use of the expression cartridges in appropriate vectors to transform plants, plant cells, tissues or parts.
摘要翻译：本发明涉及一种表达盒，其介导在植物，植物细胞，组织或抗性的部分植物腺苷酸琥珀酸合成酶的抑制剂，以及用于转化植物，植物细胞，组织或部分中使用的表达盒引入合适的载体。

7. 发明申请

WO0109355A3 PLANT S-ADENOSYLMETHIONIN:Mg-PROTOPORPHYRIN-IX-O-METHYLTRANSFERASE, PLANTS WITH VARIABLE CHLOROPHYLL CONTENTS AND/OR HERBICIDE TOLERANCE, AND METHOD FOR THE PRODUCTION THEREOF 审中-公开
标题翻译：蔬菜S-腺苷甲硫氨酸：具有用于修饰叶绿素含量和/或除草剂耐受性AND METHOD Mg的原卟啉IX-O-甲基转移植物中的
公开(公告)号：WO0109355A3
公开(公告)日：2001-09-07
申请号：PCT/EP0007472
申请日：2000-08-02
申请人： BASF AG , REINDL ANDREAS , RESKI RALF , LERCHL JENS , GRIMM BERNHARD , AL AWADI ALI
发明人： REINDL ANDREAS , RESKI RALF , LERCHL JENS , GRIMM BERNHARD , AL-AWADI ALI
IPC分类号： C07K14/415 , C12N1/19 , C12N1/21 , C12N9/10 , C12N15/82 , A01H5/00 , C12N15/11 , C12Q1/48
CPC分类号： C12N9/1007 , C07K14/415 , C12N15/8243 , C12N15/8274
摘要： The invention relates to a nucleotide sequence coding for an S-adenosylmethionin:Mg-protoporphyrin-IX-O-methyltransferase and to a method for producing genetically modified plants with a capacity to control in various ways the chlorophyll biosynthesis mode and/or having a variable chlorophyll contents and/or having a variable herbicide tolerance. The invention relates to plants with a variable chlorophyll content and plants exhibiting a variable herbicide tolerance. It also relates to the use of plant PMT-nucleotide sequences for modifying the chlorophyll content of transgenic plants and for detecting effectors, especially inhibitors of plant PMT and herbicidally effective compounds.
摘要翻译：本发明涉及一种编码植物S-腺苷甲硫氨酸的核苷酸序列：Mg的原卟啉IX-O-甲基，对于具有Chlorophyllbiosyntheseweges的改变的控制和/或叶绿素含量和/或耐除草剂的变化产生遗传修饰的植物的方法，本发明涉及具有改良的叶绿素含量和耐除草剂植物的植物。此外，本发明涉及使用新型植物PMT的核苷酸序列的用于影响的转基因植物的叶绿素含量，以及用于执行器，尤其是植物的PMT抑制剂并用的除草活性化合物的发现。

8. 发明申请

WO0138484A3 MOSS GENES FROM PHYSCOMITRELLA PATENS CODING PROTEINS INVOLVED IN THE SYNTHESIS OF POLYUNSATURATED FATTY ACIDS AND LIPIDS 审中-公开
标题翻译：在多糖脂肪酸和脂肪的合成中涉及到的编码蛋白质的来自 PHYSCOMITRELLA PATENS的MOSS基因
公开(公告)号：WO0138484A3
公开(公告)日：2001-11-01
申请号：PCT/EP0011615
申请日：2000-11-22
申请人： BASF PLANT SCIENCE GMBH
发明人： LERCHL JENS , RENZ ANDREAS , EHRHARDT THOMAS , REINDL ANDREAS , CIRPUS PETRA , BISCHOFF FRIEDRICH , FRANK MARKUS , FREUND ANNETTE , DUWENIG ELKE , SCHMIDT RALF-MICHAEL , RESKI RALF
IPC分类号： A01H11/00 , A01H13/00 , C07K14/405 , C07K14/41 , C07K14/415 , C07K16/14 , C07K16/16 , C12N1/11 , C12N1/13 , C12N1/15 , C12N1/19 , C12N1/21 , C12N15/02 , C12N15/09 , C12P7/64 , C12R1/13 , C12N15/52 , C12N5/10 , C12N9/00 , C12N15/29 , C12Q1/68 , G01N33/573
CPC分类号： C12P7/6409 , C07K14/415 , C07K2319/00 , C12P7/6427 , C12P7/6463 , C12P7/6472
摘要： Isolated nucleic acid molecules, designated LMRP nucleic acid molecules, which encode novel LMRPs from e.g. Physcomitrella patens are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing LMRP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated LMRPs, mutated LMRPs, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from transformed cells, organisms or plants based on genetic engineering of LMRP genes in these organisms.
摘要翻译：分离的核酸分子，命名为LMRP核酸分子，其编码来自例如新的LMRP。描述了小立碗藓。本发明还提供反义核酸分子，含有LMRP核酸分子的重组表达载体，以及引入了表达载体的宿主细胞。本发明还进一步提供了基于这些生物体中LMRP基因的遗传工程的分离的LMRP，突变的LMRPs，融合蛋白，抗原肽和用于改进从转化细胞，生物或植物产生所需化合物的方法。

9. 发明申请

WO0159128A2 NOVEL ELONGASE GENE AND METHOD FOR PRODUCING MULTIPLE-UNSATURATED FATTY ACIDS 审中-公开
标题翻译：新的长链脂肪酸和生产多种不饱和脂肪酸的方法
公开(公告)号：WO0159128A2
公开(公告)日：2001-08-16
申请号：PCT/EP0101346
申请日：2001-02-08
申请人： BASF AG , HEINZ ERNST , ZANK THORSTEN , ZAEHRINGER ULRICH , LERCHL JENS , RENZ ANDREAS
发明人： HEINZ ERNST , ZANK THORSTEN , ZAEHRINGER ULRICH , LERCHL JENS , RENZ ANDREAS
IPC分类号： A01H5/00 , A01K67/027 , A23K1/16 , A23L1/30 , A61K8/30 , A61K8/36 , A61K8/92 , A61K31/201 , A61K31/202 , A61P3/02 , A61P3/06 , A61P9/10 , A61P29/00 , C07K16/40 , C11C3/00 , C12N9/00 , C12N9/10 , C12N15/09 , C12N15/54 , C12N15/82 , C12P7/64 , C12Q1/02 , A61K38/45 , C11B1/00 , C11C1/00 , C12Q1/48 , G01N33/573
CPC分类号： C12N9/1029 , C12N15/8247 , C12P7/6427 , C12P7/6472
摘要： The invention relates to a novel elongase gene comprising the sequences cited in sequence SEQ ID NO:1, SEQ ID NO:3, SEQ ID NO:5 and SEQ ID NO:7 or to homologues, derivatives or analogues thereof. The invention also relates to a gene construct containing these genes or homologues, derivatives or analogues thereof, and to its use. The invention additionally relates to the vectors or transgenic organisms containing an elongase gene comprising the sequence SEQ ID NO:1, SEQ ID NO:3, SEQ ID NO:5 and SEQ ID NO:7 or containing homologues, derivatives or analogues thereof. The invention relates to the use of the elongase sequences alone or in combination with additional elongases and/or with additional fatty acid biosynthesis genes. The invention relates to a novel elongase gene comprising the sequence SEQ ID NO:1 or to homologues, derivatives or analogues thereof. The invention also relates to a method for producing multiple-unsaturated fatty acids and to a method for introducing DNA into organisms which produce large quantities of oils and, in particular, oils having a high content of unsaturated fatty acids. The invention further relates to an oil and/or to a fatty acid preparation having a high content of multiple-unsaturated fatty acids that contain at least two double bonds and/or to a triacylglycerin preparation having a high content of multiple-unsaturated fatty acids that contain at least two double bonds.
摘要翻译：本发明涉及一种在序列SEQ ID NO与一个NEUS延长酶基因：1，SEQ ID NO：3，SEQ ID NO：5和SEQ ID NO：序列或7-称他们的同系物，衍生物或类似物，涉及一种基因构建体，这些基因或他们的同系物，衍生物或类似物，以及它的用途。本发明还涉及到与序列SEQ ID NO载体或转基因生物的延长酶基因：含有7或它的同系物，衍生物或类似物：1，SEQ ID NO：3，SEQ ID NO：5和SEQ ID NO。此外，本发明涉及单独或与其他延伸酶和/或其他脂肪酸生物合成基因组合使用延长分支酶。本发明涉及具有序列SEQ ID NO：1或其同系物，衍生物或类似物的新型延伸酶基因。此外，本发明涉及生产多不饱和脂肪酸的方法，以及将DNA引入生产大量油类，特别是具有高含量不饱和脂肪酸的油类的生物中的方法。此外，本发明提供了油和/或与多不饱和脂肪酸具有至少两个双键和/或三酰甘油制剂用的多不饱和脂肪酸含量较高具有至少两个双键的涉及高含量的脂肪酸制备。

10. 发明申请

WO0131025A2 FORMYLGLYCINAMIDINRIBOTIDE SYNTHASE FROM PLANTS 审中-公开
标题翻译：植物中的FORMYLGLYCINAMIDINRIBOTIDE合成酶
公开(公告)号：WO0131025A2
公开(公告)日：2001-05-03
申请号：PCT/EP0010204
申请日：2000-10-17
申请人： BASF AG , LERCHL JENS , EHRHARDT THOMAS , SONNEWALD UWE , BOLDT RALF , KUNZE GOTTHARD
发明人： LERCHL JENS , EHRHARDT THOMAS , SONNEWALD UWE , BOLDT RALF , KUNZE GOTTHARD
IPC分类号： C12N9/00 , C12N15/82 , C12N15/52 , C12Q1/25
CPC分类号： C12N9/93 , C12N15/8242 , C12N15/8274 , G01N2333/9015
摘要： The invention relates to DNA sequences coding for a polypeptide with formylglycinamidinribotide synthase (E.C.6.3.5.3) activity. The invention further relates to the use of said nucleic acids for the production of a test system.
摘要翻译：本发明涉及编码具有甲酰甘氨酰脒核苷酸合酶（E.C.6.3.5.3）活性的多肽的DNA序列。此外，本发明涉及这些核酸用于生产测试系统的用途。

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