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1. 发明申请

WO9810074A2 ADENYLOSUCCINATE SYNTHETASE 审中-公开
标题翻译：腺苷酸合成酶
公开(公告)号：WO9810074A2
公开(公告)日：1998-03-12
申请号：PCT/EP9704812
申请日：1997-09-04
申请人： BASF AG , LERCHL JENS , SCHMIDT RALF MICHAEL , SCHIFFER HELMUT , SONNEWALD UWE , BADUR RALF
发明人： LERCHL JENS , SCHMIDT RALF-MICHAEL , SCHIFFER HELMUT , SONNEWALD UWE , BADUR RALF
IPC分类号： A01H5/00 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/10 , C12N15/09 , C12N15/82 , C12R1/125 , C12N15/52
CPC分类号： C12N9/93 , C12N15/8274
摘要： Expression cartridges are disclosed which confer to plants, plant cells, tissues or parts a resistance against inhibitors of the vegetable adenylosuccinate synthetases. Also disclosed is the use of the expression cartridges in appropriate vectors to transform plants, plant cells, tissues or parts.
摘要翻译：本发明涉及一种表达盒，其介导在植物，植物细胞，组织或抗性的部分植物腺苷酸琥珀酸合成酶的抑制剂，以及用于转化植物，植物细胞，组织或部分中使用的表达盒引入合适的载体。

2. 发明申请

WO0164861A3 PHOSPHORIBOSYL PYROPHOSPHATE SYNTHETASE 1 AS HERBICIDAL TARGET 审中-公开
标题翻译：磷酸核糖焦磷酸合成酶1作为除草TARGET
公开(公告)号：WO0164861A3
公开(公告)日：2002-10-24
申请号：PCT/EP0100971
申请日：2001-01-30
申请人： BASF AG , REINDL ANDREAS , LERCHL JENS , SONNEWALD UWE , BADUR RALF , BOLDT RALF
发明人： REINDL ANDREAS , LERCHL JENS , SONNEWALD UWE , BADUR RALF , BOLDT RALF
IPC分类号： A01H5/00 , C12N9/12 , C12N9/99 , C12N15/09 , C12N15/82 , C12Q1/02 , C12Q1/25 , C12Q1/48 , C12Q1/68
CPC分类号： C12N9/1235 , C12N15/8274 , C12Q1/48 , G01N2333/9124 , G01N2430/20 , G01N2500/20
摘要： The invention relates to the use of DNA sequences of plant origin, coding for a polypeptide with phosphoribosyl pyrophosphate synthetase 1 (E.C. 2.7.6.1) activity, for the discovery of phosphoribosyl pyrophosphate synthetase 1 inhibitors. The demonstration of phosphoribosyl pyrophosphate synthetase 1 as a herbicidal target by means of anti-sense technology is novel.
摘要翻译：本发明涉及使用DNA序列编码植物来源的与磷酸核糖焦磷酸合成酶1的多肽（EC 2.7.6.1），用于产生一个测定系统用于发现磷酸核糖焦磷酸合成酶1的抑制剂的活性的是，第一次与反义的辅助技术表明，磷酸核糖焦磷酸合成酶1表示除草目标。

3. 发明申请

WO0144276A2 MOSS GENES FROM PHYSCOMITRELLA PATENS ENCODING PROTEINS INVOLVED IN THE SYNTHESIS OF TOCOPHEROLS AND CAROTENOIDS 审中-公开
标题翻译：来自PHYSCOMITRELLA PATES的MOSS基因编码参与合成植物油和卡诺菌素的蛋白质
公开(公告)号：WO0144276A2
公开(公告)日：2001-06-21
申请号：PCT/EP0012698
申请日：2000-12-14
申请人： BASF PLANT SCIENCE GMBH , LERCHL JENS , RENZ ANDREAS , EHRHARDT THOMAS , REINDL ANDREAS , CIRPUS PETRA , BISCHOFF FRIEDRICH , FRANK MARKUS , FREUND ANNETTE , DUWENIG ELKE , SCHMIDT RALF MICHAEL , RESKI RALF , BADUR RALF
发明人： LERCHL JENS , RENZ ANDREAS , EHRHARDT THOMAS , REINDL ANDREAS , CIRPUS PETRA , BISCHOFF FRIEDRICH , FRANK MARKUS , FREUND ANNETTE , DUWENIG ELKE , SCHMIDT RALF-MICHAEL , RESKI RALF , BADUR RALF
IPC分类号： C12N9/10 , C12N15/52 , C12N15/82 , C07K14/00
CPC分类号： C12N9/1007 , C12N15/52 , C12N15/8243 , C12N15/825
摘要： Isolated nucleic acid molecules, designated TCMRP nucleic acid molecules, which encode novel TCMRPs from e.g. Physcomitrella patens are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing TCMRP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated TCMRPs, mutated TCMRPs, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from transformed cells, organisms or plants based on genetic engineering of TCMRP genes in these organisms.
摘要翻译：分离的核酸分子，命名为TCMRP核酸分子，其编码来自例如新鲜的TCMRP。描述了小立碗藓。本发明还提供反义核酸分子，含有TCMRP核酸分子的重组表达载体，以及引入了表达载体的宿主细胞。本发明还进一步提供了分离的TCMRP，突变的TCMRP，融合蛋白，抗原肽和基于这些生物体中TCMRP基因的遗传工程改进从转化细胞，生物体或植物生产所需化合物的方法。

4. 发明申请

WO0131025A2 FORMYLGLYCINAMIDINRIBOTIDE SYNTHASE FROM PLANTS 审中-公开
标题翻译：植物中的FORMYLGLYCINAMIDINRIBOTIDE合成酶
公开(公告)号：WO0131025A2
公开(公告)日：2001-05-03
申请号：PCT/EP0010204
申请日：2000-10-17
申请人： BASF AG , LERCHL JENS , EHRHARDT THOMAS , SONNEWALD UWE , BOLDT RALF , KUNZE GOTTHARD
发明人： LERCHL JENS , EHRHARDT THOMAS , SONNEWALD UWE , BOLDT RALF , KUNZE GOTTHARD
IPC分类号： C12N9/00 , C12N15/82 , C12N15/52 , C12Q1/25
CPC分类号： C12N9/93 , C12N15/8242 , C12N15/8274 , G01N2333/9015
摘要： The invention relates to DNA sequences coding for a polypeptide with formylglycinamidinribotide synthase (E.C.6.3.5.3) activity. The invention further relates to the use of said nucleic acids for the production of a test system.
摘要翻译：本发明涉及编码具有甲酰甘氨酰脒核苷酸合酶（E.C.6.3.5.3）活性的多肽的DNA序列。此外，本发明涉及这些核酸用于生产测试系统的用途。

5. 发明申请

WO0127248A8 PRPP-AMIDOTRANSFERASE FROM NICOTIANA TABACUM 审中-公开
标题翻译：来自NICOTIANA TABACUM的PRPP AMIDOTRANSFERASE
公开(公告)号：WO0127248A8
公开(公告)日：2001-08-09
申请号：PCT/EP0009839
申请日：2000-10-07
申请人： BASF AG , LERCHL JENS , EHRHARDT THOMAS , SONNEWALD UWE , BOLDT RALF
发明人： LERCHL JENS , EHRHARDT THOMAS , SONNEWALD UWE , BOLDT RALF
IPC分类号： C12N9/10 , C12N15/54 , C12N15/82 , C12Q1/48
CPC分类号： C12N15/8243 , C12N9/1077 , C12N15/8242 , C12N15/8274 , G01N2430/20 , G01N2500/00
摘要： The invention relates to DNA sequences coding for a polypeptide sequence with PRPP-amidotransferase (EC 2.4.2.14) activity. The invention relates furthermore to the use of said nucleic acids for production of a test system.
摘要翻译：本发明涉及编码具有PRPP转酰胺酶（EC 2.4.2.14）活性的多肽的DNA序列。此外，本发明涉及这些核酸用于生产测试系统的用途。

6. 发明申请

WO0125457A3 GMP SYNTHETASE DERIVED FROM PLANTS 审中-公开
标题翻译：来自植物的GMP-合成酶
公开(公告)号：WO0125457A3
公开(公告)日：2001-12-20
申请号：PCT/EP0009245
申请日：2000-09-21
申请人： BASF AG , LERCHL JENS , EHRHARDT THOMAS , SONNEWALD UWE , BOLDT RALF
发明人： LERCHL JENS , EHRHARDT THOMAS , SONNEWALD UWE , BOLDT RALF
IPC分类号： A01H5/00 , C12N9/00 , C12N9/99 , C12N15/09 , C12N15/82 , C12Q1/25 , C12Q1/68 , G01N33/15 , G01N33/50 , C12N15/52 , G01N33/53
CPC分类号： C12N9/93 , C12N15/8243 , C12N15/8274
摘要： The invention relates to a DNA that encodes a polypeptide that has GMP synthetase (EC 6.3.5.2) activity. The invention further relates to the use of said nucleic acid in the production of a test system.
摘要翻译：本发明涉及编码具有GMP合成酶（EC 6.3.5.2）活性的多肽的DNA。另外，本发明涉及该核酸在生产测试系统中的用途。

7. 发明申请

WO9737028A2 RIBOSE-5-PHOSPHATE ISOMERASE (D-RIBOSE-5-PHOSPHATE KETOL ISOMERASE, EC 5.3.1.6) 审中-公开
标题翻译：核糖-5-磷酸异构酶（D-核糖-5-磷酸酮醇异构酶，EC 5.3.1.6）
公开(公告)号：WO9737028A2
公开(公告)日：1997-10-09
申请号：PCT/EP9701539
申请日：1997-03-26
申请人： BASF AG , SCHMIDT RALF MICHAEL , LERCHL JENS , WILLIAM MARTIN , SCHNARRENBERGER CLAUS , KELLERMANN JOSEF
发明人： SCHMIDT RALF-MICHAEL , LERCHL JENS , WILLIAM MARTIN , SCHNARRENBERGER CLAUS , KELLERMANN JOSEF
IPC分类号： C12N9/90 , C12Q1/533 , C12N15/62 , A01N61/00
CPC分类号： C12Q1/533 , C12N9/90
摘要： A protein with ribose-5-phosphate isomerase activity, containing an amino acid sequence representing a partial sequence of at least 100 amino acids from SEQ ID N DEG 2, and nucleic acids coding said protein and its use for identifying herbicidal active agents.
摘要翻译：蛋白与核糖-5-磷酸异构酶活性，其包含氨基酸序列，其选自SEQ ID NO 2的至少100个氨基酸的部分序列，以及编码此蛋白质的核酸和其用于识别除草活性化合物的用途。

8. 发明申请

WO0144476A3 Moss genes from physcomitrella patens encoding proteins involved in the synthesis of carbohydrates 审中-公开
标题翻译：编码参与碳水化合物合成的蛋白质的小麦藓的苔藓基因
公开(公告)号：WO0144476A3
公开(公告)日：2002-04-25
申请号：PCT/EP0012697
申请日：2000-12-14
申请人： LERCHL JENS , RENZ ANDREAS , EHRHARDT THOMAS , REINDL ANDREAS , CIRPUS PETRA , BISCHOFF FRIEDRICH , FRANK MARKUS , FREUND ANNETTE , DUWENIG ELKE , SCHMIDT RALF-MICHAEL , RESKI RALF , BASF PLANT SCIENCE GMBH
发明人： LERCHL JENS , RENZ ANDREAS , EHRHARDT THOMAS , REINDL ANDREAS , CIRPUS PETRA , BISCHOFF FRIEDRICH , FRANK MARKUS , FREUND ANNETTE , DUWENIG ELKE , SCHMIDT RALF-MICHAEL , RESKI RALF
IPC分类号： C07K14/415 , C12N9/00 , C12N15/29 , C07K16/16 , C07K16/40 , C12P19/00 , G01N33/573 , G01N33/68
CPC分类号： C12N9/00 , C07K14/415
摘要： Isolated nucleic acid molecules, designated CMRP nucleic acid molecules, which encode novel CMRPs from Physcomitrella patens are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing CMRP nucleic acid molecules, and host cells and organisms into which the expression vectors have been introduced. The invention still further provides isolated CMRPs, mutated CMRPs, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from transformed cells based on genetic engineering of CMRP genes in this organism.
摘要翻译：描述了编码来自小立碗藓的新型CMRP的分离的核酸分子，命名为CMRP核酸分子。本发明还提供反义核酸分子，含有CMRP核酸分子的重组表达载体，以及引入表达载体的宿主细胞和生物体。本发明还进一步提供了基于该生物体中CMRP基因的遗传工程的分离的CMRP，突变CMRPs，融合蛋白，抗原肽和用于从转化细胞产生所需化合物的方法。

9. 发明申请

WO0136606A3 PROTOPORPHYRINOGEN IX OXIDASE AND THE USE THEREOF 审中-公开
标题翻译：原卟啉原Ⅸ氧化酶及其用途
公开(公告)号：WO0136606A3
公开(公告)日：2001-11-15
申请号：PCT/EP0011100
申请日：2000-11-10
申请人： BASF PLANT SCIENCE GMBH , SCHIFFER HELMUT , LERCHL JENS , GRIMM BERNHARD , LERMONTOVA INNA , VORONETSKAJA VALERIA
发明人： SCHIFFER HELMUT , LERCHL JENS , GRIMM BERNHARD , LERMONTOVA INNA , VORONETSKAJA VALERIA
IPC分类号： C12N9/02 , C12N15/82 , A01H1/00 , C07K14/415
CPC分类号： C12N9/001 , C12N15/8209 , C12N15/8243 , C12N15/8274
摘要： The present invention relates to DNA sequences coding for a polypeptide that is resistant against peroxidising inhibitors of the protoporphyrinogen IX oxidase.
摘要翻译：本发明涉及编码用于要在过氧化Protoporphrinogen-IX氧化酶抑制剂抗性的多肽的DNA序列。

10. 发明申请

WO0159128A2 NOVEL ELONGASE GENE AND METHOD FOR PRODUCING MULTIPLE-UNSATURATED FATTY ACIDS 审中-公开
标题翻译：新的长链脂肪酸和生产多种不饱和脂肪酸的方法
公开(公告)号：WO0159128A2
公开(公告)日：2001-08-16
申请号：PCT/EP0101346
申请日：2001-02-08
申请人： BASF AG , HEINZ ERNST , ZANK THORSTEN , ZAEHRINGER ULRICH , LERCHL JENS , RENZ ANDREAS
发明人： HEINZ ERNST , ZANK THORSTEN , ZAEHRINGER ULRICH , LERCHL JENS , RENZ ANDREAS
IPC分类号： A01H5/00 , A01K67/027 , A23K1/16 , A23L1/30 , A61K8/30 , A61K8/36 , A61K8/92 , A61K31/201 , A61K31/202 , A61P3/02 , A61P3/06 , A61P9/10 , A61P29/00 , C07K16/40 , C11C3/00 , C12N9/00 , C12N9/10 , C12N15/09 , C12N15/54 , C12N15/82 , C12P7/64 , C12Q1/02 , A61K38/45 , C11B1/00 , C11C1/00 , C12Q1/48 , G01N33/573
CPC分类号： C12N9/1029 , C12N15/8247 , C12P7/6427 , C12P7/6472
摘要： The invention relates to a novel elongase gene comprising the sequences cited in sequence SEQ ID NO:1, SEQ ID NO:3, SEQ ID NO:5 and SEQ ID NO:7 or to homologues, derivatives or analogues thereof. The invention also relates to a gene construct containing these genes or homologues, derivatives or analogues thereof, and to its use. The invention additionally relates to the vectors or transgenic organisms containing an elongase gene comprising the sequence SEQ ID NO:1, SEQ ID NO:3, SEQ ID NO:5 and SEQ ID NO:7 or containing homologues, derivatives or analogues thereof. The invention relates to the use of the elongase sequences alone or in combination with additional elongases and/or with additional fatty acid biosynthesis genes. The invention relates to a novel elongase gene comprising the sequence SEQ ID NO:1 or to homologues, derivatives or analogues thereof. The invention also relates to a method for producing multiple-unsaturated fatty acids and to a method for introducing DNA into organisms which produce large quantities of oils and, in particular, oils having a high content of unsaturated fatty acids. The invention further relates to an oil and/or to a fatty acid preparation having a high content of multiple-unsaturated fatty acids that contain at least two double bonds and/or to a triacylglycerin preparation having a high content of multiple-unsaturated fatty acids that contain at least two double bonds.
摘要翻译：本发明涉及一种在序列SEQ ID NO与一个NEUS延长酶基因：1，SEQ ID NO：3，SEQ ID NO：5和SEQ ID NO：序列或7-称他们的同系物，衍生物或类似物，涉及一种基因构建体，这些基因或他们的同系物，衍生物或类似物，以及它的用途。本发明还涉及到与序列SEQ ID NO载体或转基因生物的延长酶基因：含有7或它的同系物，衍生物或类似物：1，SEQ ID NO：3，SEQ ID NO：5和SEQ ID NO。此外，本发明涉及单独或与其他延伸酶和/或其他脂肪酸生物合成基因组合使用延长分支酶。本发明涉及具有序列SEQ ID NO：1或其同系物，衍生物或类似物的新型延伸酶基因。此外，本发明涉及生产多不饱和脂肪酸的方法，以及将DNA引入生产大量油类，特别是具有高含量不饱和脂肪酸的油类的生物中的方法。此外，本发明提供了油和/或与多不饱和脂肪酸具有至少两个双键和/或三酰甘油制剂用的多不饱和脂肪酸含量较高具有至少两个双键的涉及高含量的脂肪酸制备。

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