专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08260439B2 Nerve stimulation patches and methods for stimulating selected nerves 有权
标题翻译：神经刺激斑块和刺激选择神经的方法
公开(公告)号：US08260439B2
公开(公告)日：2012-09-04
申请号：US11941508
申请日：2007-11-16
申请人： Anthony DiUbaldi , Michael Tracey , Rex O. Bare , Bradley Sargent , Stephen B. Wahlgren
发明人： Anthony DiUbaldi , Michael Tracey , Rex O. Bare , Bradley Sargent , Stephen B. Wahlgren
IPC分类号： A61N1/18
CPC分类号： A61N1/0456 , A61N1/0452 , A61N1/0492 , A61N1/0496 , A61N1/36007 , A61N1/36014 , A61N1/36021 , A61N1/375 , A61N1/3756 , A61N1/3758 , H05K3/281 , H05K2201/2018
摘要： A selective nerve stimulation patch includes a substrate having a top surface and a bottom surface, integrated components overlying the top surface of the substrate and being electrically interconnected with one another for generating at least one nerve stimulating signal, electrodes integrated into the substrate and exposed at the bottom surface thereof for applying the at least one nerve stimulating signal to a target nerve, a waterproof, breathable cover overlying the substrate and the integrated components, and a support flange surrounding the substrate and coupling the cover and the substrate together. The support flange has a top surface that slopes downwardly toward an outer perimeter thereof, and at least a portion of the cover conforms to the sloping top surface of the support flange. In one embodiment, the patch generates a high frequency waveform with properties such as amplitude, frequency and the like chosen so as to overcome tissue impedance and the stimulation threshold of the target nerve. The modulated waveform is the waveform obtained by modulating the carrier waveform by a pulse envelope.
摘要翻译：选择性神经刺激贴片包括具有顶表面和底表面的基底，整合的元件覆盖在基底的顶表面上并且彼此电互连以产生至少一种神经刺激信号，集成到基底中并暴露于其底表面用于将至少一个神经刺激信号施加到目标神经，覆盖在基底和集成部件上的防水透气盖，以及围绕基底并将盖和基底连接在一起的支撑凸缘。支撑凸缘具有朝向其外周向下倾斜的顶表面，并且盖的至少一部分符合支撑凸缘的倾斜顶表面。在一个实施例中，贴片产生具有所选择的诸如振幅，频率等特性的高频波形，以便克服组织阻抗和目标神经的刺激阈值。调制波形是通过用脉冲包络调制载波波形而获得的波形。

2. 发明申请

US20090132018A1 Nerve Stimulation Patches And Methods For Stimulating Selected Nerves 有权
标题翻译：神经刺激补丁和刺激所选神经的方法
公开(公告)号：US20090132018A1
公开(公告)日：2009-05-21
申请号：US11941508
申请日：2007-11-16
申请人： Anthony DiUbaldi , Michael Tracey , Rex O. Bare , Bradley Sargent , Stephen B. Wahlgren
发明人： Anthony DiUbaldi , Michael Tracey , Rex O. Bare , Bradley Sargent , Stephen B. Wahlgren
IPC分类号： A61N1/04
CPC分类号： A61N1/0456 , A61N1/0452 , A61N1/0492 , A61N1/0496 , A61N1/36007 , A61N1/36014 , A61N1/36021 , A61N1/375 , A61N1/3756 , A61N1/3758 , H05K3/281 , H05K2201/2018
摘要： A selective nerve stimulation patch includes a substrate having a top surface and a bottom surface, integrated components overlying the top surface of the substrate and being electrically interconnected with one another for generating at least one nerve stimulating signal, electrodes integrated into the substrate and exposed at the bottom surface thereof for applying the at least one nerve stimulating signal to a target nerve, a waterproof, breathable cover overlying the substrate and the integrated components, and a support flange surrounding the substrate and coupling the cover and the substrate together. The support flange has a top surface that slopes downwardly toward an outer perimeter thereof, and at least a portion of the cover conforms to the sloping top surface of the support flange. In one embodiment, the patch generates a high frequency waveform with properties such as amplitude, frequency and the like chosen so as to overcome tissue impedance and the stimulation threshold of the target nerve. The modulated waveform is the waveform obtained by modulating the carrier waveform by a pulse envelope.
摘要翻译：选择性神经刺激贴片包括具有顶表面和底表面的基底，整合的元件覆盖在基底的顶表面上并且彼此电互连以产生至少一种神经刺激信号，集成到基底中并暴露于其底表面用于将至少一个神经刺激信号施加到目标神经，覆盖在基底和集成部件上的防水透气盖，以及围绕基底并将盖和基底连接在一起的支撑凸缘。支撑凸缘具有朝向其外周向下倾斜的顶表面，并且盖的至少一部分符合支撑凸缘的倾斜顶表面。在一个实施例中，贴片产生具有所选择的诸如振幅，频率等特性的高频波形，以便克服组织阻抗和目标神经的刺激阈值。调制波形是通过用脉冲包络调制载波波形而获得的波形。

3. 发明授权

US08128576B2 System and method for urodynamic evaluation utilizing micro electro-mechanical system technology 有权
标题翻译：使用微机电系统技术进行尿动力学评估的系统和方法
公开(公告)号：US08128576B2
公开(公告)日：2012-03-06
申请号：US11635403
申请日：2006-12-07
申请人： Michael R. Tracey , Anthony DiUbaldi , Stephen Wahlgren , Rex O. Bare , Bradley J. Sargent
发明人： Michael R. Tracey , Anthony DiUbaldi , Stephen Wahlgren , Rex O. Bare , Bradley J. Sargent
IPC分类号： A61B5/00 , A61B1/307
CPC分类号： A61B5/14507 , A61B5/0031 , A61B5/205 , A61B5/208 , A61B5/6874 , A61B2562/028
摘要： An implantable urodynamic system includes an implantable first device deployable in a patient's bladder, an implantable second device deployable in a patient's vaginal canal, and a data acquisition and analysis module or processing unit external to the body of the patient. The first device includes a magnet and an inductive coil, and the second device includes a magnet, an inductive coil and a battery. When deployed in the patient's body, attraction between the magnets maintains the two devices in close proximity to one another to effect an inductive coupling between the coils so that the first device may be powered by the battery of the second device. The urodynamic system is intended to facilitate measurement, collection, and wireless transmission of real-time, or near real-time, data (bladder pressure, abdominal pressure, and temperature) from an ambulatory patient. This data is of value in diagnosing a number of abnormal bladder conditions, such as infection, overactive bladder, bladder spasms, and the like.
摘要翻译：可植入尿动力系统包括可部署在患者膀胱中的可植入第一装置，可植入患者阴道内的可植入第二装置，以及在患者身体外部的数据采集和分析模块或处理单元。第一装置包括磁体和感应线圈，并且第二装置包括磁体，感应线圈和电池。当部署在患者体内时，磁体之间的吸引力将两个装置彼此紧密地保持在彼此附近以实现线圈之间的感应耦合，使得第一装置可以由第二装置的电池供电。尿动力系统旨在便于来自流动患者的实时或近实时数据（膀胱压力，腹压和温度）的测量，收集和无线传输。该数据在诊断膀胱膀胱状况异常，例如感染，膀胱过度活动症，膀胱痉挛等中是有价值的。

4. 发明申请

US20080139875A1 System and method for urodynamic evaluation utilizing micro electro-mechanical system technology 有权
标题翻译：使用微机电系统技术进行尿动力学评估的系统和方法
公开(公告)号：US20080139875A1
公开(公告)日：2008-06-12
申请号：US11635403
申请日：2006-12-07
申请人： Michael R. Tracey , Anthony DiUbaldi , Stephen Wahlgren , Rex O. Bare , Bradley J. Sargent
发明人： Michael R. Tracey , Anthony DiUbaldi , Stephen Wahlgren , Rex O. Bare , Bradley J. Sargent
IPC分类号： A61B5/00
CPC分类号： A61B5/14507 , A61B5/0031 , A61B5/205 , A61B5/208 , A61B5/6874 , A61B2562/028
摘要： An implantable urodynamic system includes an implantable first device deployable in a patient's bladder, an implantable second device deployable in a patient's vaginal canal, and a data acquisition and analysis module or processing unit external to the body of the patient. The first device includes a magnet and an inductive coil, and the second device includes a magnet, an inductive coil and a battery. When deployed in the patient's body, attraction between the magnets maintains the two devices in close proximity to one another to effect an inductive coupling between the coils so that the first device may be powered by the battery of the second device. The urodynamic system is intended to facilitate measurement, collection, and wireless transmission of real-time, or near real-time, data (bladder pressure, abdominal pressure, and temperature) from an ambulatory patient. This data is of value in diagnosing a number of abnormal bladder conditions, such as infection, overactive bladder, bladder spasms, and the like.
摘要翻译：可植入尿动力系统包括可部署在患者膀胱中的可植入第一装置，可植入患者阴道内的可植入第二装置，以及在患者身体外部的数据采集和分析模块或处理单元。第一装置包括磁体和感应线圈，并且第二装置包括磁体，感应线圈和电池。当部署在患者体内时，磁体之间的吸引力将两个装置彼此紧密地保持在彼此附近以实现线圈之间的感应耦合，使得第一装置可以由第二装置的电池供电。尿动力系统旨在便于来自流动患者的实时或近实时数据（膀胱压力，腹压和温度）的测量，收集和无线传输。该数据在诊断膀胱膀胱状况异常，例如感染，膀胱过度活动症，膀胱痉挛等中是有价值的。

5. 发明授权

US09402999B2 Transdermal medical patch 有权
标题翻译：透皮贴片
公开(公告)号：US09402999B2
公开(公告)日：2016-08-02
申请号：US13464634
申请日：2012-05-04
申请人： Stephen Wahlgren , Martin J. Nohilly , Anthony R. DiUbaldi , Rex O. Bare , Bradley Sargent , Michael W. Ammerman , Jeffrey C. Smith , Kathryn M. Kukulka
发明人： Stephen Wahlgren , Martin J. Nohilly , Anthony R. DiUbaldi , Rex O. Bare , Bradley Sargent , Michael W. Ammerman , Jeffrey C. Smith , Kathryn M. Kukulka
IPC分类号： A61N1/04 , A61N1/30 , A61N1/36
CPC分类号： A61N1/303 , A61N1/0428 , A61N1/0456 , A61N1/0492 , A61N1/36014
摘要： A medical patch having a multi-piece bottom liner including a central liner sequentially removable independently of two outer perimeter liners. The multi-piece liner covering two adhesives of different peel force. Removal of the central liner exposes a first temporary/repositionable adhesive. Once properly positioned, the outer perimeter liners are removed to expose a second stronger adhesive. A foam cushioning layer is disposed beneath and extends beyond a footprint of every printed circuit board to prevent skin irritation. The medical patch may be designed specifically for stimulation of the sacral (S3 foramen) spinal nerve without the use of a separate mechanical placement tool or assistance by another.
摘要翻译：一种具有多片底部衬垫的医疗贴片，其包括独立于两个外周边衬垫顺序地移除的中心衬垫。多片衬里覆盖两种不同剥离力的粘合剂。去除中心衬垫露出第一个临时/可重新定位的粘合剂。一旦正确定位，移除外周衬里以露出第二较强的粘合剂。泡沫缓冲层设置在每个印刷电路板的下方并延伸超过每个印刷电路板的印迹，以防止皮肤刺激。医疗补片可以专门设计用于刺激骶骨（S3孔）脊神经，而不使用单独的机械放置工具或由另一机械辅助。

6. 发明授权

US09333333B2 Offset electrode 有权
标题翻译：胶印电极
公开(公告)号：US09333333B2
公开(公告)日：2016-05-10
申请号：US13402081
申请日：2012-02-22
申请人： Rex O. Bare , Bradley Sargent
发明人： Rex O. Bare , Bradley Sargent
IPC分类号： A61N1/00 , A61N1/04 , A61B5/0408 , A61N1/36
CPC分类号： A61N1/0456 , A61B5/04087 , A61B2562/125 , A61N1/0492 , A61N1/0496 , A61N1/36021
摘要： An electrode including a non-conductive substrate having a top surface and at least one channel extending therethrough, an electrically conductive trace material positioned adjacent a portion of the top surface of the non-conductive substrate and extending through the channel, and adapted for electrically coupling to a power source, and a second electrically conductive material that is inert or more corrosion resistant than the trace material. The second material is positioned adjacent to and entirely covering a top surface of the trace material. The electrode further includes a conductive hydrogel laterally offset from the trace material, the hydrogel may be positioned adjacent to a portion of a top surface of the second electrically conductive material.
摘要翻译：一种电极，包括具有顶表面和延伸穿过其中的至少一个通道的非导电衬底，导电迹线材料定位成邻近非导电衬底的顶表面的一部分并且延伸穿过沟道，并适于电耦合电源，以及比微量材料更惰性或更耐腐蚀的第二导电材料。第二材料定位成邻近并完全覆盖痕量材料的顶表面。电极还包括横向偏离痕量材料的导电水凝胶，水凝胶可以邻近第二导电材料的顶表面的一部分定位。

7. 发明授权

US08126530B2 Offset electrode 有权
标题翻译：胶印电极
公开(公告)号：US08126530B2
公开(公告)日：2012-02-28
申请号：US12605409
申请日：2009-10-26
申请人： Rex O. Bare , Bradley Sargent
发明人： Rex O. Bare , Bradley Sargent
IPC分类号： A61B5/04 , A61N1/00
CPC分类号： A61N1/0456 , A61B5/04087 , A61B2562/125 , A61N1/0492 , A61N1/0496 , A61N1/36021
摘要： An electrode including a non-conductive substrate having a top surface and at least one channel extending therethrough, an electrically conductive trace material positioned adjacent a portion of the top surface of the non-conductive substrate and extending through the channel, and adapted for electrically coupling to a power source, and second and third electrically conductive materials that are inert or more corrosion resistant than the trace material. The second material is positioned adjacent to and entirely covering a top surface of the trace material, and the third material is positioned adjacent to and entirely covering a top surface of the second electrically conductive material, and covers a portion of a top surface of the non-conductive substrate surrounding the second electrically conductive material. The electrode further includes a conductive hydrogel positioned adjacent to a portion of a top surface of the third electrically conductive material, but laterally offset from the trace material.
摘要翻译：一种电极，包括具有顶表面和延伸穿过其中的至少一个通道的非导电衬底，导电迹线材料定位成邻近非导电衬底的顶表面的一部分并且延伸穿过沟道，并适于电耦合电源，以及比痕量材料更惰性或更耐腐蚀的第二和第三导电材料。第二材料定位成邻近并完全覆盖迹线材料的顶表面，并且第三材料定位成邻近并完全覆盖第二导电材料的顶表面，并且覆盖非金属材料的顶表面的一部分导电基体包围第二导电材料。电极还包括邻近第三导电材料的顶表面的一部分定位的导电水凝胶，但是与痕量材料横向偏移。

8. 发明申请

US20110094773A1 OFFSET ELECTRODE 有权
标题翻译：偏移电极
公开(公告)号：US20110094773A1
公开(公告)日：2011-04-28
申请号：US12605409
申请日：2009-10-26
申请人： Rex O. Bare , Bradley Sargent
发明人： Rex O. Bare , Bradley Sargent
IPC分类号： H05K1/11 , H05K1/09
CPC分类号： A61N1/0456 , A61B5/04087 , A61B2562/125 , A61N1/0492 , A61N1/0496 , A61N1/36021
摘要： An electrode including a non-conductive substrate having a top surface and at least one channel extending therethrough, an electrically conductive trace material positioned adjacent a portion of the top surface of the non-conductive substrate and extending through the channel, and adapted for electrically coupling to a power source, and second and third electrically conductive materials that are inert or more corrosion resistant than the trace material. The second material is positioned adjacent to and entirely covering a top surface of the trace material, and the third material is positioned adjacent to and entirely covering a top surface of the second electrically conductive material, and covers a portion of a top surface of the non-conductive substrate surrounding the second electrically conductive material. The electrode further includes a conductive hydrogel positioned adjacent to a portion of a top surface of the third electrically conductive material, but laterally offset from the trace material.
摘要翻译：一种电极，包括具有顶表面和延伸穿过其中的至少一个通道的非导电衬底，导电迹线材料定位成邻近非导电衬底的顶表面的一部分并且延伸穿过沟道，并且适于电耦合电源，以及比痕量材料更惰性或更耐腐蚀的第二和第三导电材料。第二材料定位成邻近并完全覆盖迹线材料的顶表面，并且第三材料被定位成与第二导电材料的顶表面相邻并且完全覆盖第二导电材料的顶表面，并且覆盖非金属材料的顶表面的一部分导电基体包围第二导电材料。电极还包括邻近第三导电材料的顶表面的一部分定位的导电水凝胶，但是与痕量材料横向偏移。

9. 发明申请

US20120145440A1 Offset Electrode 有权
标题翻译：偏移电极
公开(公告)号：US20120145440A1
公开(公告)日：2012-06-14
申请号：US13402081
申请日：2012-02-22
申请人： Rex O. Bare , Bradley Sargent
发明人： Rex O. Bare , Bradley Sargent
IPC分类号： H05K1/09
CPC分类号： A61N1/0456 , A61B5/04087 , A61B2562/125 , A61N1/0492 , A61N1/0496 , A61N1/36021
摘要： An electrode including a non-conductive substrate having a top surface and at least one channel extending therethrough, an electrically conductive trace material positioned adjacent a portion of the top surface of the non-conductive substrate and extending through the channel, and adapted for electrically coupling to a power source, and a second electrically conductive material that is inert or more corrosion resistant than the trace material. The second material is positioned adjacent to and entirely covering a top surface of the trace material. The electrode further includes a conductive hydrogel laterally offset from the trace material, the hydrogel may be positioned adjacent to a portion of a top surface of the second electrically conductive material.
摘要翻译：一种电极，包括具有顶表面和延伸穿过其中的至少一个通道的非导电衬底，导电迹线材料定位成邻近非导电衬底的顶表面的一部分并且延伸穿过沟道，并适于电耦合电源，以及比微量材料更惰性或更耐腐蚀的第二导电材料。第二材料定位成邻近并完全覆盖痕量材料的顶表面。电极还包括横向偏离痕量材料的导电水凝胶，水凝胶可以邻近第二导电材料的顶表面的一部分定位。

10. 发明申请

US20130296996A1 Transdermal Medical Patch 有权
标题翻译：透皮医疗贴片
公开(公告)号：US20130296996A1
公开(公告)日：2013-11-07
申请号：US13464634
申请日：2012-05-04
申请人： Stephen Wahlgren , Martin J. Nohilly , Anthony R. DiUbaldi , Rex O. Bare , Bradley Sargent , Michael W. Ammerman , Jeffrey C. Smith , Kathryn M. Kukulka
发明人： Stephen Wahlgren , Martin J. Nohilly , Anthony R. DiUbaldi , Rex O. Bare , Bradley Sargent , Michael W. Ammerman , Jeffrey C. Smith , Kathryn M. Kukulka
IPC分类号： A61N1/04
CPC分类号： A61N1/303 , A61N1/0428 , A61N1/0456 , A61N1/0492 , A61N1/36014
摘要： A medical patch having a multi-piece bottom liner including a central liner sequentially removable independently of two outer perimeter liners. The multi-piece liner covering two adhesives of different peel force. Removal of the central liner exposes a first temporary/repositionable adhesive. Once properly positioned, the outer perimeter liners are removed to expose a second stronger adhesive. A foam cushioning layer is disposed beneath and extends beyond a footprint of every printed circuit board to prevent skin irritation. The medical patch may be designed specifically for stimulation of the sacral (S3 foramen) spinal nerve without the use of a separate mechanical placement tool or assistance by another.
摘要翻译：一种具有多片底部衬垫的医疗贴片，其包括独立于两个外周边衬垫顺序地移除的中心衬垫。多片衬里覆盖两种不同剥离力的粘合剂。去除中心衬垫露出第一个临时/可重新定位的粘合剂。一旦正确定位，移除外周衬里以露出第二较强的粘合剂。泡沫缓冲层设置在每个印刷电路板的下方并延伸超过每个印刷电路板的印迹，以防止皮肤刺激。医疗补片可以专门设计用于刺激骶骨（S3孔）脊神经，而不使用单独的机械放置工具或由另一机械辅助。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式