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1. 发明授权

US06675033B1 Magnetic resonance imaging guidewire probe 有权
标题翻译：磁共振成像导丝探针
公开(公告)号：US06675033B1
公开(公告)日：2004-01-06
申请号：US09536090
申请日：2000-03-24
申请人： Albert C. Lardo , Xiaoming Yang , Ergin Atalar , Parag Karmarkar , Elliott R. McVeigh , Henry R. Halperin , Christine Enger McNamara , Paul A. Bottomley
发明人： Albert C. Lardo , Xiaoming Yang , Ergin Atalar , Parag Karmarkar , Elliott R. McVeigh , Henry R. Halperin , Christine Enger McNamara , Paul A. Bottomley
IPC分类号： A61B5055
CPC分类号： G01R33/287 , G01R33/34084
摘要： The invention describes a system, method, and means for an MRI guidewire that can be visible on an MRI, can act as an antenna and receive MRI signals from surrounding subject matter, and can allow the use of multiple interventional tools without removal of the guidewire from a subject.
摘要翻译：本发明描述了可以在MRI上可见的用于MRI导丝的系统，方法和装置，可用作天线并从周围主题接收MRI信号，并且可以允许使用多个介入工具而不去除导丝从一个主题。

2. 发明授权

US07848788B2 Magnetic resonance imaging probe 有权
标题翻译：磁共振成像探头
公开(公告)号：US07848788B2
公开(公告)日：2010-12-07
申请号：US10123065
申请日：2002-04-11
申请人： Steve Tulley , Albert C. Lardo , Parag Karmarkar , Elliot McVeigh , Henry R. Halperin , Christine Enger McNamara , Paul A. Bottomley , Ergin Atalar , Xiaoming Yang
发明人： Steve Tulley , Albert C. Lardo , Parag Karmarkar , Elliot McVeigh , Henry R. Halperin , Christine Enger McNamara , Paul A. Bottomley , Ergin Atalar , Xiaoming Yang
IPC分类号： A61B5/055
CPC分类号： G01R33/34084 , A61M25/09 , G01R33/287 , G01R33/34053 , G01R33/3657 , H01Q1/36 , H01Q1/362 , H01Q1/40 , H01Q1/42 , H01Q1/44 , H01Q11/08
摘要： Herein is disclosed a magnetic resonance imaging probe, having a probe shaft including a magnetic resonance antenna, and a spring tip attached to a distal end of the antenna.
摘要翻译：本文公开了一种磁共振成像探头，其具有包括磁共振天线的探针轴以及连接到天线远端的弹簧尖端。

3. 发明授权

US06628980B2 Apparatus, systems, and methods for in vivo magnetic resonance imaging 有权
公开(公告)号：US06628980B2
公开(公告)日：2003-09-30
申请号：US09817893
申请日：2001-03-26
申请人： Ergin Atalar , Paul A. Bottomley , Parag Karmarkar , Albert C. Lardo , Elias Zerhouni
发明人： Ergin Atalar , Paul A. Bottomley , Parag Karmarkar , Albert C. Lardo , Elias Zerhouni
IPC分类号： A61B5055
CPC分类号： A61B1/00154 , A61B5/055 , A61B34/20 , A61B2034/2051 , A61B2090/374 , A61B2090/3958 , G01R33/285 , G01R33/34007 , G01R33/34084
摘要： The apparatus, systems and methods of the present invention provide for MRI sleeves, probes, and combinations thereof adapted for insertion into a subject, in order to internally image regions of the subject.

4. 发明授权

US07599729B2 Evaluating the urethra and the periurethral tissues 有权
标题翻译：评估尿道和尿道周围组织
公开(公告)号：US07599729B2
公开(公告)日：2009-10-06
申请号：US11136329
申请日：2005-05-24
申请人： Ergin Atalar , Harald Hartmut Quick , Parag Karmarkar
发明人： Ergin Atalar , Harald Hartmut Quick , Parag Karmarkar
IPC分类号： A61B5/055
CPC分类号： G01R33/34084 , A61B1/273 , A61B1/303 , A61B1/307 , A61B1/31 , A61B5/055 , A61B5/415 , A61B5/418 , A61B5/4381 , G01R33/285 , G01R33/34007 , G01R33/341 , H01Q1/36 , H01Q1/362 , H01Q1/40 , H01Q1/44 , H01Q11/08
摘要： Systems and methods for the evaluation of the urethra and periurethral tissues may involve an MRI coil adapted for insertion into the male, female or pediatric urethra. The MRI coil may be in electrical communication with an interface circuit made up of a tuning-matching circuit, a decoupling circuit and a balun circuit. The interface circuit may also be in electrical communication with a MRI machine. In certain practices, the present invention provides methods for the diagnosis and treatment of conditions involving the urethra and periurethral tissues, including disorders of the female pelvic floor, conditions of the prostate and anomalies of the pediatric pelvis.
摘要翻译：用于评估尿道和尿道周围组织的系统和方法可以包括适于插入到男性，女性或儿科尿道中的MRI线圈。 MRI线圈可以与由调谐匹配电路，去耦电路和平衡 - 不平衡转换电路组成的接口电路电连通。接口电路也可以与MRI机器电连通。在某些实践中，本发明提供了用于诊断和治疗涉及尿道和尿道周围组织的病症的方法，包括女性骨盆底部疾病，前列腺疾病和儿科骨盆异常。

5. 发明申请

US20060106303A1 Interventional devices for chronic total occlusion recanalization under MRI guidance 审中-公开
标题翻译： MRI指导下慢性全闭塞再通的介入装置
公开(公告)号：US20060106303A1
公开(公告)日：2006-05-18
申请号：US11131304
申请日：2005-05-18
申请人： Parag Karmarkar , Ergin Atalar , Robert Lederman , Amish Raval
发明人： Parag Karmarkar , Ergin Atalar , Robert Lederman , Amish Raval
IPC分类号： A61B5/05
CPC分类号： G01R33/286 , A61B90/39 , A61B2090/3958 , A61M25/00 , A61M2025/1079 , G01R33/287 , G01R33/34084
摘要： Disclosed is a guide catheter that includes one or more RF antennas to enhance the visibility of the guide catheter in MR imagery. One embodiment of the guide catheter includes a loop coil at the distal end of the guide catheter and a loopless antenna between the distal end and the proximal end. By combining a loop coil and a loopless antenna on the catheter, the shaft of the catheter may be visible in MR imagery while the distal end may appear in the MR imagery more brightly than the shaft.
摘要翻译：公开了一种引导导管，其包括一个或多个RF天线，以增强导引导管在MR图像中的可视性。引导导管的一个实施例包括在引导导管的远端处的环形线圈和在远端和近端之间的无凹凸天线。通过在导管上组合环形线圈和无孔天线，导管的轴可以在MR图像中可见，而远端可能比轴更明亮地出现在MR图像中。

6. 发明申请

US20060122493A1 Evaluating the urethra and the periurethral Tissues 有权
标题翻译：评估尿道和尿道周围组织
公开(公告)号：US20060122493A1
公开(公告)日：2006-06-08
申请号：US11136329
申请日：2005-05-24
申请人： Ergin Atalar , Harald Quick , Parag Karmarkar
发明人： Ergin Atalar , Harald Quick , Parag Karmarkar
IPC分类号： A61B5/05
CPC分类号： G01R33/34084 , A61B1/273 , A61B1/303 , A61B1/307 , A61B1/31 , A61B5/055 , A61B5/415 , A61B5/418 , A61B5/4381 , G01R33/285 , G01R33/34007 , G01R33/341 , H01Q1/36 , H01Q1/362 , H01Q1/40 , H01Q1/44 , H01Q11/08
摘要： Systems and methods for the evaluation of the urethra and periurethral tissues may involve an MRI coil adapted for insertion into the male, female or pediatric urethra. The MRI coil may be in electrical communication with an interface circuit made up of a tuning-matching circuit, a decoupling circuit and a balun circuit. The interface circuit may also be in electrical communication with a MRI machine. In certain practices, the present invention provides methods for the diagnosis and treatment of conditions involving the urethra and periurethral tissues, including disorders of the female pelvic floor, conditions of the prostate and anomalies of the pediatric pelvis.
摘要翻译：用于评估尿道和尿道周围组织的系统和方法可以包括适于插入到男性，女性或儿科尿道中的MRI线圈。 MRI线圈可以与由调谐匹配电路，去耦电路和平衡 - 不平衡转换电路组成的接口电路电连通。接口电路也可以与MRI机器电连通。在某些实践中，本发明提供了用于诊断和治疗涉及尿道和尿道周围组织的病症的方法，包括女性骨盆底部疾病，前列腺疾病和儿科骨盆异常。

7. 发明授权

US06898454B2 Systems and methods for evaluating the urethra and the periurethral tissues 有权
标题翻译：用于评估尿道和尿道周围组织的系统和方法
公开(公告)号：US06898454B2
公开(公告)日：2005-05-24
申请号：US09824536
申请日：2001-04-02
申请人： Ergin Atalar , Harald Hartmann Quick , Parag Karmarkar
发明人： Ergin Atalar , Harald Hartmann Quick , Parag Karmarkar
IPC分类号： A61B1/273 , A61B1/303 , A61B1/307 , A61B1/31 , A61B5/055 , G01R33/28 , G01R33/34 , H01Q1/36 , H01Q1/40 , H01Q1/44 , H01Q11/08 , A01B5/05
CPC分类号： G01R33/34084 , A61B1/273 , A61B1/303 , A61B1/307 , A61B1/31 , A61B5/055 , A61B5/415 , A61B5/418 , A61B5/4381 , G01R33/285 , G01R33/34007 , G01R33/341 , H01Q1/36 , H01Q1/362 , H01Q1/40 , H01Q1/44 , H01Q11/08
摘要： The present invention provides systems and methods for the evaluation of the urethra and periurethral tissues using an MRI coil adapted for insertion into the male, female or pediatric urethra. The MRI coil may be in electrical communication with an interface circuit made up of a tuning-matching circuit, a decoupling circuit and a balun circuit. The interface circuit may also be in electrical communication with a MRI machine. In certain practices, the present invention provides methods for the diagnosis and treatment of conditions involving the urethra and periurethral tissues, including disorders of the female pelvic floor, conditions of the prostate and anomalies of the pediatric pelvis.
摘要翻译：本发明提供了使用适于插入到男性，女性或儿科尿道中的MRI线圈来评估尿道和尿道周围组织的系统和方法。 MRI线圈可以与由调谐匹配电路，去耦电路和平衡 - 不平衡转换电路组成的接口电路电连通。接口电路也可以与MRI机器电连通。在某些实践中，本发明提供了用于诊断和治疗涉及尿道和尿道周围组织的病症的方法，包括女性骨盆底部疾病，前列腺疾病和儿科骨盆异常。

8. 发明授权

US06904307B2 Magnetic resonance probes 有权
标题翻译：磁共振探针
公开(公告)号：US06904307B2
公开(公告)日：2005-06-07
申请号：US10448736
申请日：2003-05-29
申请人： Parag Karmarkar , Ingmar Viohl
发明人： Parag Karmarkar , Ingmar Viohl
IPC分类号： G01R33/28 , A61B5/05 , G01V3/00
CPC分类号： G01R33/287
摘要： A magnetic resonance probe may include a plurality of center conductors, at least some center conductors including a conductive core and an insulator disposed at least partially about the core along at least a portion of the core, a first dielectric layer disposed at least partially about the plurality of center conductors in a proximal portion of the probe, an outer conductive layer at least partially disposed about the first dielectric layer, and a plurality of electrodes, at least one electrode being coupled to one of the center conductors and disposed at least partly on a probe surface.
摘要翻译：磁共振探针可以包括多个中心导体，至少一些中心导体包括导电芯和至少部分地沿着芯的至少一部分围绕芯设置的绝缘体，第一介电层至少部分地围绕芯在探针的近端部分中的多个中心导体，至少部分地布置在第一介电层周围的外部导电层，以及多个电极，至少一个电极耦合到一个中心导体并且至少部分地设置在探针表面。

9. 发明授权

US07918819B2 Variable curve catheter 有权
标题翻译：可变曲线导管
公开(公告)号：US07918819B2
公开(公告)日：2011-04-05
申请号：US10534362
申请日：2003-11-14
申请人： Parag Karmarkar , Robert J. Lederman
发明人： Parag Karmarkar , Robert J. Lederman
IPC分类号： A61M31/00
CPC分类号： A61M25/0147 , A61M25/0138 , A61M25/0144
摘要： Disclosed is a deflectable tip guiding device, such as a catheter, that enables a physician, or other health care personnel, to vary the radius of curvature of the tip of the device. In one embodiment, a guiding device includes an elongate body and a deflectable distal tip. An elongate stiffener tube is coupled to the body for longitudinal movement relative thereto and has a distal end spaced a variable distance from the distal end of the tip, thereby serving as a fulcrum for the tip. Longitudinal movement of the stiffener tube relative to the body varies the distance between the distal ends of the tip and tube, which in turn causes a corresponding increase or decrease in the radius of curvature of the tip.
摘要翻译：公开了一种可偏转的末梢引导装置，例如导管，其使得医师或其他保健人员能够改变装置的尖端的曲率半径。在一个实施例中，引导装置包括细长主体和可偏转的远侧末端。细长的加强管耦合到主体，用于相对于其纵向移动，并且具有与尖端的远端间隔开可变距离的远端，从而用作尖端的支点。加强管相对于主体的纵向运动改变了尖端和管的远端之间的距离，这又导致尖端的曲率半径的相应增加或减小。

10. 再颁专利

USRE42856E1 Magnetic resonance probes 有权
标题翻译：磁共振探针
公开(公告)号：USRE42856E1
公开(公告)日：2011-10-18
申请号：US11810679
申请日：2007-06-06
申请人： Parag Karmarkar , Ingmar Viohl
发明人： Parag Karmarkar , Ingmar Viohl
IPC分类号： A61B5/05 , G01V3/00
CPC分类号： G01R33/287
摘要： A magnetic resonance probe may include a plurality of center conductors, at least some center conductors including a conductive core and an insulator disposed at least partially about the core along at least a portion of the core, a first dielectric layer disposed at least partially about the plurality of center conductors in a proximal portion of the probe, an outer conductive layer at least partially disposed about the first dielectric layer, and a plurality of electrodes, at least one electrode being coupled to one of the center conductors and disposed at least partly on a probe surface.
摘要翻译：磁共振探针可以包括多个中心导体，至少一些中心导体包括导电芯和至少部分地沿着芯的至少一部分围绕芯设置的绝缘体，第一介电层至少部分地围绕芯在探针的近端部分中的多个中心导体，至少部分地布置在第一介电层周围的外部导电层，以及多个电极，至少一个电极耦合到一个中心导体并且至少部分地设置在探针表面。

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