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1. 发明申请

WO0062837A2 CATHETER WITH MULTIPLE HEATING/COOLING FIBERS EMPLOYING FIBER SPREADING FEATURES 审中-公开
标题翻译：带多个加热/冷却纤维的导管采用纤维扩展功能
公开(公告)号：WO0062837A2
公开(公告)日：2000-10-26
申请号：PCT/US0010494
申请日：2000-04-19
申请人： ALSIUS CORP , WALKER BLAIR D , EVANS SCOTT M , BALDING DAVID P , HALLAM GREGG , SHIMADA LYNN M
发明人： WALKER BLAIR D , EVANS SCOTT M , BALDING DAVID P , HALLAM GREGG , SHIMADA LYNN M
IPC分类号： A61M25/00 , A61B18/00 , A61F7/00 , A61F7/12 , A61M1/36 , A61M5/44 , A61M
CPC分类号： A61F7/123 , A61B2018/00011 , A61F7/12 , A61F2007/0054 , A61F2007/126 , A61M1/369 , A61M5/44 , A61M25/00 , A61M25/0009 , A61M2205/36
摘要： This invention is a catheter (110) using multiple hollow fibers to carry a heating/cooling fluid employs fiber (108) spreading features to improve heat transfer, and prevent clotting of body fluids within which the catheter is immersed. The catheter includes an outer tube (102) surrounding an inner tube (104). The inner tube conveys fluids in one direction, a passageway between inner, and outer tubes conveying fluids in the opposite direction. The catheter's distal end is closed, but the proximal end is open to permit introduction of a heating or cooling fluid into the inner tube, and withdrawal of the fluid from the passageway between the inner, and outer tubes. At the tubes' distal end resides a proximal fluid transfer housing (106) coupled to multiple hollow heat exchange fibers. The distal ends of these fibers may be commonly connected to a distal fluid transfer housing (110), and optional reservoir (112). Actuating structure(s) may be included to spread the fibers.
摘要翻译：本发明是使用多个中空纤维承载加热/冷却流体的导管（110），该加热/冷却流体采用纤维（108）扩散特征以改善热传递，并且防止导管浸入其中的体液的凝结。导管包括围绕内管（104）的外管（102）。内管在一个方向上输送流体，内管和外管之间的通道沿相反方向输送流体。导管的远端是封闭的，但是近端是敞开的，以允许将加热或冷却流体引入内管，并且将流体从内管和外管之间的通道中取出。在管的远端存在耦合到多个中空热交换纤维的近端流体转移壳体（106）。这些纤维的远端可以共同连接到远端流体转移壳体（110）和任选的储存器（112）。可以包括致动结构以展开纤维。

2. 发明申请

WO0062837A9 CATHETER WITH MULTIPLE HEATING/COOLING FIBERS EMPLOYING FIBER SPREADING FEATURES 审中-公开
标题翻译：带多个加热/冷却纤维的导管采用纤维扩展功能
公开(公告)号：WO0062837A9
公开(公告)日：2002-03-14
申请号：PCT/US0010494
申请日：2000-04-19
申请人： ALSIUS CORP , WALKER BLAIR D , EVANS SCOTT M , BALDING DAVID P , HALLAM GREGG , SHIMADA LYNN M
发明人： WALKER BLAIR D , EVANS SCOTT M , BALDING DAVID P , HALLAM GREGG , SHIMADA LYNN M
IPC分类号： A61M25/00 , A61B18/00 , A61F7/00 , A61F7/12 , A61M1/36 , A61M5/44 , A61B18/04 , F28F1/00 , H05B7/12
CPC分类号： A61F7/123 , A61B2018/00011 , A61F7/12 , A61F2007/0054 , A61F2007/126 , A61M1/369 , A61M5/44 , A61M25/00 , A61M25/0009 , A61M2205/36
摘要： This invention is a catheter (110) using multiple hollow fibers to carry a heating/cooling fluid employs fiber (108) spreading features to improve heat transfer, and prevent clotting of body fluids within which the catheter is immersed. The catheter includes an outer tube (102) surrounding an inner tube (104). The inner tube conveys fluids in one direction, a passageway between inner, and outer tubes conveying fluids in the opposite direction. The catheter's distal end is closed, but the proximal end is open to permit introduction of a heating or cooling fluid into the inner tube, and withdrawal of the fluid from the passageway between the inner, and outer tubes. At the tubes' distal end resides a proximal fluid transfer housing (106) coupled to multiple hollow heat exchange fibers. The distal ends of these fibers may be commonly connected to a distal fluid transfer housing (110), and optional reservoir (112). Actuating structure(s) may be included to spread the fibers.
摘要翻译：本发明是使用多个中空纤维承载加热/冷却流体的导管（110），该加热/冷却流体采用纤维（108）扩散特征以改善热传递，并且防止导管浸入其中的体液的凝结。导管包括围绕内管（104）的外管（102）。内管在一个方向上输送流体，内管和外管之间的通道沿相反方向输送流体。导管的远端是封闭的，但是近端是敞开的，以允许将加热或冷却流体引入内管，并且将流体从内管和外管之间的通道中取出。在管的远端存在耦合到多个中空热交换纤维的近端流体转移壳体（106）。这些纤维的远端可以共同连接到远端流体转移壳体（110）和任选的储存器（112）。可以包括致动结构以展开纤维。

3. 发明申请

WO0130413A9 DUAL BALLOON CENTRAL VENOUS LINE CATHETER TEMPERATURE CONTROL SYSTEM 审中-公开
标题翻译：双壁中央通风管路温度控制系统
公开(公告)号：WO0130413A9
公开(公告)日：2002-08-08
申请号：PCT/US0041524
申请日：2000-10-24
申请人： ALSIUS CORP , PHAM NORA TRAN , SHIMADA LYNN M , EVANS SCOTT M , WALKER BLAIR D
发明人： PHAM NORA TRAN , SHIMADA LYNN M , EVANS SCOTT M , WALKER BLAIR D
IPC分类号： A61B17/00 , A61B18/00 , A61F7/12 , A61M1/36 , A61M5/44 , A61M29/00
CPC分类号： A61F7/123 , A61B2018/00011 , A61F2007/126 , A61M1/369 , A61M5/44
摘要： A system for controlling a patient temperature uses a central venous line catheter (100) having axially spaced distal and proximal heat exchange balloons (102/104). The central venous line catheter (100) is provided with one or more lumens (128) for providing access to the central blood supply of the patient, and with additional lumens (106/108) for communicating heat exchange fluid to the balloons (102/104). Heat exchange fluid temperature is controlled through a feed back loop in which patient temperature is sensed and used to control a temperature control unit (50) comprising a heating device and/or a cooling device in heat exchange relationship with the heat exchange fluid. A tubing set (120/122) transports the heat exchange fluid between the central venous line (100) and the temperature control unit (50), with a pump serving to circulate the fluid in a closed fluid circuit in the system.
摘要翻译：用于控制患者温度的系统使用具有轴向间隔开的远端和近端热交换球囊（102/104）的中心静脉导管（100）。中心静脉导管（100）设置有一个或多个腔（128），用于提供对患者的中心血液供应的通路，以及用于将热交换流体传送到气囊（102 / 104）。热交换流体温度通过反馈回路来控制，其中感测患者温度并用于控制包括与热交换流体热交换关系的加热装置和/或冷却装置的温度控制单元（50）。管道组（120/122）在中心静脉管线（100）和温度控制单元（50）之间输送热交换流体，其中泵用于将流体循环在系统中的封闭流体回路中。

4. 发明申请

WO0130413A2 DUAL BALLOON CENTRAL VENOUS LINE CATHETER TEMPERATURE CONTROL SYSTEM 审中-公开
标题翻译：双壁中央静电线路导管温度控制系统
公开(公告)号：WO0130413A2
公开(公告)日：2001-05-03
申请号：PCT/US0041524
申请日：2000-10-24
申请人： ALSIUS CORP , PHAM NORA TRAN , SHIMADA LYNN M , EVANS SCOTT M , WALKER BLAIR D
发明人： PHAM NORA TRAN , SHIMADA LYNN M , EVANS SCOTT M , WALKER BLAIR D
IPC分类号： A61B17/00 , A61B18/00 , A61F7/12 , A61M1/36 , A61M5/44 , A61M
CPC分类号： A61F7/123 , A61B2018/00011 , A61F2007/126 , A61M1/369 , A61M5/44
摘要： A system for controlling a patient temperature uses a central venous line catheter (100) having axially spaced distal and proximal heat exchange balloons (102/104). The central venous line catheter (100) is provided with one or more lumens (128) for providing access to the central blood supply of the patient, and with additional lumens (106/108) for communicating heat exchange fluid to the balloons (102/104). Heat exchange fluid temperature is controlled through a feed back loop in which patient temperature is sensed and used to control a temperature control unit (50) comprising a heating device and/or a cooling device in heat exchange relationship with the heat exchange fluid. A tubing set (120/122) transports the heat exchange fluid between the central venous line (100) and the temperature control unit (50), with a pump serving to circulate the fluid in a closed fluid circuit in the system.
摘要翻译：用于控制患者体温的系统使用具有轴向间隔开的远端和近端热交换球囊（102/104）的中心静脉导管（100）。中心静脉导管（100）设置有一个或多个腔（128），用于提供对患者的中央血液供应的通路，以及用于将热交换流体传送到气囊（102/108）的附加腔（106/108） 104）。热交换流体温度通过反馈回路来控制，其中感测患者温度并用于控制包括与热交换流体热交换关系的加热装置和/或冷却装置的温度控制单元（50）。管组（120/122）在中央静脉管路（100）和温度控制单元（50）之间输送热交换流体，其中泵用于使流体循环在系统中的封闭流体回路中。

5. 发明专利

AU7880900A Central venous catheter with heat exchange properties 未知
公开(公告)号：AU7880900A
公开(公告)日：2001-03-13
申请号：AU7880900
申请日：2000-08-16
申请人： ALSIUS CORP
发明人： SHIMADA LYNN M , WORTHEN WILLIAM J , EVANS SCOTT M , LUO XIA , PECOR ROBERT , WALKER BLAIR
IPC分类号： A61B17/00 , A61B17/34 , A61B18/00 , A61F2/958 , A61F7/10 , A61F7/12 , A61M1/36 , A61M5/44 , A61M25/00 , A61M25/06 , A61M25/14 , A61B5/00
摘要： An introducer sheath (42) for a central venous catheter (54) includes a sheath body (56) and a temperature sensor (80) mounted distally on the body (56). Also a jugular vein catheter system is disclosed having a heat exchange region and an oxygen sensor connected to an optical fiber.

6. 发明公开

EP1204368A4 CENTRAL VENOUS CATHETER WITH HEAT EXCHANGE PROPERTIES 有权
标题翻译：有热交换性能中心静脉导管
公开(公告)号：EP1204368A4
公开(公告)日：2006-06-28
申请号：EP00968972
申请日：2000-08-16
申请人： ALSIUS CORP
发明人： SHIMADA LYNN M , WORTHEN WILLIAM J , EVANS SCOTT M , LUO XIA , PECOR ROBERT , WALKER BLAIR
IPC分类号： A61B17/00 , A61B17/34 , A61B18/00 , A61F2/958 , A61F7/10 , A61F7/12 , A61M1/36 , A61M5/44 , A61M25/00 , A61M25/06 , A61M25/14 , A61B5/00
CPC分类号： A61F7/123 , A61B17/3415 , A61B17/3417 , A61B17/3421 , A61B17/3462 , A61B2017/00084 , A61B2018/00011 , A61B2018/00023 , A61F7/10 , A61F7/12 , A61F2007/126 , A61M1/369 , A61M5/44 , A61M25/00 , A61M25/0028 , A61M25/0032 , A61M25/0662 , A61M25/1011 , A61M2025/0031 , A61M2025/0036 , A61M2025/1013 , A61M2205/36
摘要： An introducer sheath (42) for a central venous catheter (54) includes a sheath body (56) and a temperature sensor (80) mounted distally on the body (56).

7. 发明专利

AU4647400A Catheter with multiple heating/cooling fibers employing fiber spreading features 未知
公开(公告)号：AU4647400A
公开(公告)日：2000-11-02
申请号：AU4647400
申请日：2000-04-19
申请人： ALSIUS CORP
发明人： WALKER BLAIR D , EVANS SCOTT M , BALDING DAVID P , HALLAM GREGG , SHIMADA LYNN M
IPC分类号： A61M25/00 , A61B18/00 , A61F7/00 , A61F7/12 , A61M1/36 , A61M5/44
摘要： A catheter using multiple hollow fibers to carry a heating/cooling fluid employs fiber spreading features to improve heat transfer and help prevent clotting of body fluids within which the catheter is immersed. The catheter includes a length of outer tube surrounding an inner tube. The inner tube conveys fluids in one direction, and the passageway between inner and outer tubes conveys fluids in the opposite direction. The inner and outer tubes have proximal distal ends. The distal end is closed, but the proximal end is open to permit introduction of a heating or cooling fluid into the inner tube, and withdrawal of the fluid from the passageway between the inner and outer tubes. At the tubes' distal end resides a proximal fluid transfer housing coupled to multiple hollow heat exchange fibers. The distal ends of these fibers may be commonly connected to a distal fluid transfer housing and optional reservoir, which cooperatively return fluid to the passageway between inner and outer tubes. In another embodiment, each fiber includes both outflowing and return lumens, enabling the fibers' distal ends to freely move about. In another embodiment, each fiber proceeds outward from the proximal fluid transfer housing, and returns back to form a loop. In each different embodiment, the invention includes one or more actuating structures to spread the fibers. The actuating structure may include, for example, fiber shaping, a retractable spreading member, elastic bias built into the fibers, etc.

8. 发明专利

DE60039888D1 未知
公开(公告)号：DE60039888D1
公开(公告)日：2008-09-25
申请号：DE60039888
申请日：2000-08-16
申请人： ALSIUS CORP
发明人： SHIMADA LYNN M , WORTHEN WILLIAM J , EVANS SCOTT M , LUO XIA , PECOR ROBERT , WALKER BLAIR
IPC分类号： A61B5/00 , A61B17/00 , A61B17/34 , A61B18/00 , A61F2/958 , A61F7/10 , A61F7/12 , A61M1/36 , A61M5/44 , A61M25/00 , A61M25/06 , A61M25/14
摘要： An introducer sheath (42) for a central venous catheter (54) includes a sheath body (56) and a temperature sensor (80) mounted distally on the body (56). Also a jugular vein catheter system is disclosed having a heat exchange region and an oxygen sensor connected to an optical fiber.

9. 发明专利

AU2470601A Dual balloon central venous line catheter temperature control system 未知
公开(公告)号：AU2470601A
公开(公告)日：2001-05-08
申请号：AU2470601
申请日：2000-10-24
申请人： ALSIUS CORP
发明人： PHAM NORA TRAN , SHIMADA LYNN M , EVANS SCOTT M , WALKER BLAIR D
IPC分类号： A61B17/00 , A61B18/00 , A61F7/12 , A61M1/36 , A61M5/44

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