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1. 发明申请

US20050107723A1 Methods and apparatus for determining work performed by an individual from measured physiological parameters 审中-公开
标题翻译：用于根据测量的生理参数确定个体进行的工作的方法和装置
公开(公告)号：US20050107723A1
公开(公告)日：2005-05-19
申请号：US10779149
申请日：2004-02-12
申请人： Thomas Wehman , Serjan Nikolic
发明人： Thomas Wehman , Serjan Nikolic
IPC分类号： A61B20060101 , A61B5/103 , A61B5/11 , A61B5/117
CPC分类号： A61B5/4866 , A61B5/1118 , A61B2562/0219 , G06F19/3481
摘要： Methods and apparatus for gathering and processing data sensed on an individual from portable heart monitors and accelerometers aligned along three orthogonal axes determine substantially equivalent oxygen consumption information during an individual's physical activities without requiring gas-flow or gas-analysis equipment. Such information promotes calculations of physiological energy expenditures, and analyses of the accelerometer data associated with a specific sensing location on an individual's body provide indication of the particular physical activity for selecting appropriate scaling factors and filtering requirements in analyzing the data to determine various parameters indicative of the individual's expenditure of physiological energy, and other health-oriented factors.
摘要翻译：用于收集和处理在个人身上活动的便携式心脏监测器和加速度计上检测到的数据的方法和装置在个体的身体活动期间确定基本相当的氧消耗信息，而不需要气流或气体分析设备。这样的信息促进生理能量消耗的计算，并且与个人身体上的特定感测位置相关联的加速度计数据的分析提供了用于选择合适的缩放因子的特定身体活动的指示，并且在分析数据中过滤需求以确定指示个人生理能量支出等健康导向因素。

2. 发明申请

US20050054938A1 Method and apparatus including altimeter and accelerometers for determining work performed by an individual 审中-公开
标题翻译：包括用于确定个人执行的工作的高度计和加速度计的方法和装置
公开(公告)号：US20050054938A1
公开(公告)日：2005-03-10
申请号：US10901675
申请日：2004-07-28
申请人： Thomas Wehman , Serjan Nikolic , Milos Backovic , Peter Muller , Jim Lovewell , Katie Peuvrelle
发明人： Thomas Wehman , Serjan Nikolic , Milos Backovic , Peter Muller , Jim Lovewell , Katie Peuvrelle
IPC分类号： A61B20060101 , A61B5/02 , A61B5/024 , A61B5/22 , H01R13/44
CPC分类号： A61B5/222 , A61B5/024 , A61B5/061 , A63B24/0062 , A63B2220/803 , A63B2230/06
摘要： Method and calculations determine an individual's, or several individuals' simultaneous rates of oxygen consumption, maximum rates of oxygen consumption, heart rates, calorie expenditures, and METS (multiples of metabolic resting rate) in order to determine the amounts of work that is performed by the individual's body. A heart monitor measures the heart rate, and an accelerometer measures the acceleration of the body along one or more axes. An altimeter measures change in altitude, a glucose monitor measures glucose in tissue and blood, and thermometers, thermistors, or thermocouples measure body temperature. Data including body fat and blood pressure measurements are stored locally and transferred to a processor for calculation of the rate of physiological energy expenditure. Certain cardiovascular parameters are mathematically determined. Comparison of each axis response to the individual's moment can be used to identify the type of activity performed and the information may be used to accurately calculate total energy expenditure for each physical activity. Energy expenditure may be calculated by assigning a separate proportionality coefficient to each axis and tabulating the resulting filtered dynamic acceleration over time, or by comparison with previously predetermined expenditures for each activity type. A comparison of total energy expenditure from the current activity is compared with expenditure from a previous activity, or with a baseline expenditure rate to assess the level of current expenditure. A measure of the individual's cardio-vascular health may be obtained by monitoring the heart's responses to various types of activity and to total energy expended.
摘要翻译：方法和计算确定个体或几个个体的同时氧消耗率，最大消耗氧量，心率，卡路里支出和METS（代谢静息率的倍数），以确定由个人的身体。心脏监测器测量心率，加速度计测量身体沿着一个或多个轴的加速度。高度计测量高度变化，葡萄糖监测器测量组织和血液中的葡萄糖，温度计，热敏电阻或热电偶测量体温。包括身体脂肪和血压测量的数据在本地存储并转移到处理器以计算生理能量消耗的速率。数学确定某些心血管参数。可以使用每个轴响应与个人时刻的比较来识别所执行的活动的类型，并且可以使用该信息来精确地计算每个身体活动的总能量消耗。能量消耗可以通过为每个轴分配一个比例系数来计算，并且随着时间的推移列出所得到的过滤的动态加速度，或通过与每个活动类型的先前预定的支出进行比较来计算能量消耗。将当前活动的总能源消耗与以前活动的支出进行比较，或与基准支出率进行比较，以评估当前支出水平。通过监测心脏对各种活动的反应和消耗的总能量，可以获得个体心血管健康的量度。

3. 发明申请

US20080077179A1 Pretreatment method for enhancing tissue adhesion 审中-公开
标题翻译：增强组织粘连的预处理方法
公开(公告)号：US20080077179A1
公开(公告)日：2008-03-27
申请号：US11986470
申请日：2007-11-21
申请人： Stuart Edwards , Thomas Wehman , Theodore Parker , Eugene Skalnyi , Theodore Kucklick , John Evans
发明人： Stuart Edwards , Thomas Wehman , Theodore Parker , Eugene Skalnyi , Theodore Kucklick , John Evans
IPC分类号： A61B17/04
CPC分类号： A61B17/00491 , A61B17/0057 , A61B17/3415 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1487 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61B2017/00022 , A61B2017/00084 , A61B2017/00106 , A61B2017/003 , A61B2017/00495 , A61B2017/005 , A61B2017/00637 , A61B2017/0065 , A61B2017/00672 , A61B2017/22067 , A61B2017/3492 , A61B2017/4216 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00065 , A61B2018/00077 , A61B2018/00083 , A61B2018/00113 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00494 , A61B2018/00559 , A61B2018/00577 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00755 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00827 , A61B2018/00869 , A61B2018/00875 , A61B2018/00886 , A61B2018/00892 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/00982 , A61B2018/046 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/1467 , A61B2018/1472 , A61B2090/064 , A61B2090/3614 , A61B2090/3782 , A61B2218/002 , A61M3/0279 , A61M16/0858 , A61M25/0662 , A61M25/1002 , A61M2016/0027 , A61M2025/1052 , A61M2025/1086
摘要： A closure device is provided for sealing a puncture in a body vessel. The closure device includes an energy delivery device for delivering energy to tissue adjacent the vessel puncture which enhances an adhesiveness of the tissue to a closure composition precursor. The closure device includes a sealer/dilator for dilating tissue adjacent a vessel puncture, at least one closure composition precursor lumen within the sealer/dilator having an entrance port adjacent the proximal end of the sealer/dilator through which one or more fluent closure composition precursors can be delivered into the closure composition precursor lumen and an exit port adjacent the distal end of the sealer/dilator through which the one or more fluent closure composition precursors can be delivered outside the vessel adjacent the vessel puncture, and a plugging catheter for positioning within the vessel puncture, the plugging catheter extending distally from the sealer/dilator and including at least one position sensing mechanism such that the exit port of the closure composition precursor lumen is outside the vessel when the at least one position sensing mechanism is detected outside the vessel.
摘要翻译：提供封闭装置用于密封身体容器中的穿刺。闭合装置包括能量递送装置，用于将能量递送到邻近容器穿刺的组织，这提高了组织与封闭组合物前体的粘附性。闭合装置包括用于扩张邻近容器穿刺的组织的封闭器/扩张器，密封器/扩张器内的至少一个闭合组合物前体管腔具有邻近密封器/扩张器的近端的入口端口，通过该封闭器/扩张器的一个或多个流体封闭组合物前体可以将其输送到闭合组合物前体管腔和邻近密封剂/扩张器远端的出口，一个或多个流体封闭组合物前体可通过该出口端口被输送到与血管穿刺相邻的血管外部，容器穿刺，插塞导管从密封剂/扩张器向远端延伸并且包括至少一个位置感测机构，使得当在容器外部检测到至少一个位置感测机构时，闭合组合物前体腔的出口在容器外部。

4. 发明申请

US20060254603A1 Universal introducer 审中-公开
标题翻译：通用导引器
公开(公告)号：US20060254603A1
公开(公告)日：2006-11-16
申请号：US11491763
申请日：2006-07-24
申请人： Stuart Edwards , Ronald Lax , Theodore Parker , Thomas Wehman , Theodore Kucklick
发明人： Stuart Edwards , Ronald Lax , Theodore Parker , Thomas Wehman , Theodore Kucklick
IPC分类号： A61B18/18
CPC分类号： A61B17/00491 , A61B17/0057 , A61B17/3415 , A61B18/14 , A61B18/1482 , A61B18/1487 , A61B2017/00084 , A61B2017/00495 , A61B2017/005 , A61B2017/00637 , A61B2017/0065 , A61B2017/00672 , A61B2017/3441 , A61B2017/3492 , A61B2018/0063 , A61B2090/064 , A61M25/0662
摘要： A device for introducing a catheter into a vessel through a puncture in a vessel and for sealing the puncture. The device includes an elongated body having a proximal end and a distal end sized to be positioned within a tissue site which includes the puncture. The elongated body includes a utility lumen sized to allow a catheter to be delivered through the utility lumen. The utility lumen is positioned within the elongated body so positioning the elongated body within the tissue site allows a catheter delivered through the utility lumen to enter the vessel. The elongated body also includes a closure lumen having an entrance port. A closure composition can be delivered through the entrance port into the closure lumen. The closure lumen also includes an exit port adjacent the distal end of the elongated body. The closure composition delivered into the closure lumen can be delivered through the exit port to the tissue site adjacent the puncture.
摘要翻译：一种用于通过穿孔在容器中将导管引入容器并用于密封穿刺的装置。该装置包括细长体，其具有近端和远端，其尺寸设置成包括穿刺的组织部位内。细长主体包括大小适于允许导管通过效用管腔输送的应用腔。实用管腔定位在细长体内，从而将细长体定位在组织部位内，允许通过效用腔输送的导管进入血管。细长体还包括具有入口的封闭腔。封闭组合物可通过入口端口输送到封闭腔。闭合腔还包括邻近细长体的远端的出口。输送到闭合腔内的封闭组合物可以通过出口传送到穿刺附近的组织部位。

5. 发明授权

US06743248B2 Pretreatment method for enhancing tissue adhesion 有权
标题翻译：增强组织粘连的预处理方法
公开(公告)号：US06743248B2
公开(公告)日：2004-06-01
申请号：US09548145
申请日：2000-04-13
申请人： Stuart D. Edwards , Thomas Wehman , Theodore L. Parker , Eugene V. Skalnyi , Theodore Kucklick , John Evans
发明人： Stuart D. Edwards , Thomas Wehman , Theodore L. Parker , Eugene V. Skalnyi , Theodore Kucklick , John Evans
IPC分类号： A61B1704
CPC分类号： A61B17/00491 , A61B17/0057 , A61B17/3415 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1487 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61B2017/00022 , A61B2017/00084 , A61B2017/00106 , A61B2017/003 , A61B2017/00495 , A61B2017/005 , A61B2017/00637 , A61B2017/0065 , A61B2017/00672 , A61B2017/22067 , A61B2017/3492 , A61B2017/4216 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00065 , A61B2018/00077 , A61B2018/00083 , A61B2018/00113 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00494 , A61B2018/00559 , A61B2018/00577 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00755 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00827 , A61B2018/00869 , A61B2018/00875 , A61B2018/00886 , A61B2018/00892 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/00982 , A61B2018/046 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/1467 , A61B2018/1472 , A61B2090/064 , A61B2090/3614 , A61B2090/3782 , A61B2218/002 , A61M3/0279 , A61M16/0833 , A61M16/0858 , A61M25/0662 , A61M25/1002 , A61M2016/0027 , A61M2025/1052 , A61M2025/1086
摘要： A closure device is provided for sealing a puncture in a body vessel. The closure device includes an energy delivery device for delivering energy to tissue adjacent the vessel puncture which enhances an adhesiveness of the tissue to a closure composition precursor. The closure device includes a sealer/dilator for dilating tissue adjacent a vessel puncture, at least one closure composition precursor lumen within The sealer/dilator having an entrance part adjacent the proximal end of the sealer/dilator through which one or more fluent closure composition precursors can be delivered into the closure composition precursor lumen and an exit port adjacent the distal end of the sealer/dilator through which the one or more fluent closure composition precursors can be delivered outside the vessel adjacent the vessel puncture, and a plugging catheter for positioning within the vessel puncture, the plugging catheter extending distally from the sealer/dilator and including at least one position sensing mechanism such that the exit port of the closure composition precursor lumen is outside the vessel when the at least one position sensing mechanism is detected outside the vessel.
摘要翻译：提供封闭装置用于密封身体容器中的穿刺。闭合装置包括能量递送装置，用于将能量递送到邻近容器穿刺的组织，这提高了组织与封闭组合物前体的粘附性。闭合装置包括用于扩张邻近容器穿刺的组织的封闭器/扩张器，所述封闭器/扩张器内的至少一个闭合组合物前体管腔具有邻近密封器/扩张器的近端的入口部分，通过所述入口部分，一个或多个流体封闭组合物前体可以将其输送到闭合组合物前体管腔和邻近密封剂/扩张器远端的出口，一个或多个流体封闭组合物前体可通过该出口端口被输送到与血管穿刺相邻的血管外部，容器穿刺，插塞导管从密封剂/扩张器向远端延伸并且包括至少一个位置感测机构，使得当在容器外部检测到至少一个位置感测机构时，闭合组合物前体腔的出口在容器外部。

6. 发明授权

US06302898B1 Devices for sealing punctures in body vessels 失效
标题翻译：用于密封体内穿刺的装置
公开(公告)号：US06302898B1
公开(公告)日：2001-10-16
申请号：US09021708
申请日：1998-02-10
申请人： Stuart D. Edwards , Thomas Wehman , Theodore L. Parker , Eugene V. Skalnyi , Theodore Kucklick , John Evans
发明人： Stuart D. Edwards , Thomas Wehman , Theodore L. Parker , Eugene V. Skalnyi , Theodore Kucklick , John Evans
IPC分类号： A61B1708
CPC分类号： A61B17/0057 , A61B17/00491 , A61B17/3415 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1487 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61B2017/00084 , A61B2017/00106 , A61B2017/003 , A61B2017/00495 , A61B2017/005 , A61B2017/00637 , A61B2017/0065 , A61B2017/3492 , A61B2017/4216 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00065 , A61B2018/00077 , A61B2018/00083 , A61B2018/00113 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00494 , A61B2018/00559 , A61B2018/00577 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00755 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00827 , A61B2018/00869 , A61B2018/00875 , A61B2018/00886 , A61B2018/00892 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/00982 , A61B2018/046 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/1467 , A61B2018/1472 , A61B2090/064 , A61B2090/3614 , A61B2090/3782 , A61B2218/002 , A61M3/0279 , A61M16/0841 , A61M16/0858 , A61M25/0662 , A61M25/1002 , A61M2016/0027 , A61M2025/1052 , A61M2025/1086 , A61N1/056 , A61N1/06 , A61N1/08 , A61N1/40
摘要： A closure device is provided for sealing a puncture in a body vessel. The closure device includes an energy delivery device for delivering energy to tissue adjacent the vessel puncture which enhances an adhesiveness of the tissue to a closure composition precursor. The closure device includes a sealer/dilator for dilating tissue adjacent a vessel puncture, at least one closure composition precursor lumen within the sealer/dilator having an entrance port adjacent the proximal end of the sealer/dilator through which one or more fluent closure composition precursors can be delivered into the closure composition precursor lumen and an exit port adjacent the distal end of the sealer/dilator through which the one or more fluent closure composition precursors can be delivered outside the vessel adjacent the vessel puncture, and a plugging catheter for positioning within the vessel puncture, the plugging catheter extending distally from the sealer/dilator and including at least one position sensing mechanism such that the exit port of the closure composition precursor lumen is outside the vessel when the at least one position sensing mechanism is detected to be outside the vessel.
摘要翻译：提供封闭装置用于密封身体容器中的穿刺。闭合装置包括能量递送装置，用于将能量递送到邻近容器穿刺的组织，这提高了组织与封闭组合物前体的粘附性。闭合装置包括用于扩张邻近容器穿刺的组织的封闭器/扩张器，密封器/扩张器内的至少一个闭合组合物前体管腔具有邻近密封器/扩张器的近端的入口端口，通过该封闭器/扩张器的一个或多个流体封闭组合物前体可以将其输送到闭合组合物前体管腔和邻近密封剂/扩张器远端的出口，一个或多个流体封闭组合物前体可通过该出口端口被输送到与血管穿刺相邻的血管外部，容器穿刺，插塞导管从密封剂/扩张器向远端延伸并且包括至少一个位置感测机构，使得当检测到至少一个位置感测机构处于外部时，封闭组合物前体腔的出口在容器外部船只。

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