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1. 发明授权

US06451559B1 Expression vector for improved production of polypeptides in yeast 失效
标题翻译：用于改善酵母中多肽生成的表达载体
公开(公告)号：US06451559B1
公开(公告)日：2002-09-17
申请号：US09518658
申请日：2000-03-03
申请人： Thomas Schreier , Rainer Voegeli
发明人： Thomas Schreier , Rainer Voegeli
IPC分类号： C12P2102
CPC分类号： C12N9/0089 , C12N15/81
摘要： A new expression vector for the production of a polypeptide in yeast. The vector includes a sequence coding for the polypeptide and other sequences allowing expression of the polypeptide only in yeast. The other sequences lack any non-yeast sequences. Other embodiments include a yeast strain comprising such a vector, a method for the production of the vector, a method for the production of the yeast strain by transformation of a yeast strain with the new vector, and a method for the production of a polypeptide in the transformed yeast strain by fermentation thereof followed by isolation of the polypeptide.
摘要翻译：用于在酵母中产生多肽的新表达载体。载体包括编码多肽的序列和允许仅在酵母中表达多肽的其它序列。其他序列缺少任何非酵母序列。其它实施方案包括含有这种载体的酵母菌株，用于生产载体的方法，通过用新载体转化酵母菌株来生产酵母菌株的方法，以及用于产生多肽的方法通过发酵转化酵母菌株，然后分离多肽。

2. 发明授权

US06451293B1 Combination of erythrulose and a reducing sugar with self-tanning properties 有权
标题翻译：赤藓糖与还原糖的结合具有自鞣性能
公开(公告)号：US06451293B1
公开(公告)日：2002-09-17
申请号：US09380651
申请日：2000-01-05
申请人： Thomas Schreier , Roland Jermann
发明人： Thomas Schreier , Roland Jermann
IPC分类号： A61K742
CPC分类号： A61Q19/04 , A61K8/35 , A61K8/60 , A61K2800/592 , Y10S514/937 , Y10S514/938
摘要： The invention relates to an active ingredient combination containing erythrulose and a further reducing sugar with self-tanning properties, for example, dihydroxyacetone, which combination is used for artificially tanning the skin. Compared with compounds containing, for example, only dihydroxyacetone, said active ingredient combination and cosmetic compounds based thereon result in an even and longer-lasting colouring of the skin and prevent skin dehydration and uneven flaking.
摘要翻译：本发明涉及含有红酵母和具有自晒黑性能的另外还原糖的活性成分组合，例如二羟基丙酮，该组合用于人造鞣皮肤。与含有例如仅二羟基丙酮的化合物相比，所述活性成分组合和基于其的化妆品化合物导致皮肤均匀且持久的着色，并防止皮肤脱水和不均匀剥落。

3. 发明申请

US20120144839A1 METHOD FOR STARTING A COMBINED CYCLE POWER PLANT 有权
标题翻译：组合循环发电厂的启动方法
公开(公告)号：US20120144839A1
公开(公告)日：2012-06-14
申请号：US12964982
申请日：2010-12-10
申请人： Andreas Ehrsam , Thomas Schreier
发明人： Andreas Ehrsam , Thomas Schreier
IPC分类号： F02C7/26
CPC分类号： F01D19/02 , F02C7/26 , F05D2270/303
摘要： A method for starting a combined cycle power plant (1) includes loading the gas turbine unit (2), providing a starting temperature (Tsrart) for the steam supplied to the steam turbine (5), while the control valve (7) is regulated controlling the temperature of the steam at a temperature substantially equal to the starting temperature (Tstart) at a position (P2) downstream of the control valve (7) and upstream of the rotor (8), when the control valve (7) is substantially fully open, supplying steam to the steam turbine (5) at the starting temperature (Tstart). The steam temperature is controlled by controlling the steam temperature upstream of the control valve (7) in accordance with the temperature drop caused by the control valve (7) when the steam passes through it.
摘要翻译：一种启动联合循环发电厂（1）的方法包括：在控制阀（7）被调节的情况下装载燃气轮机单元（2），为供应给蒸汽轮机（5）的蒸汽提供启动温度（Tsrart）当控制阀（7）基本上等于控制阀（7）下游的位置（P2）和转子（8）的上游时，基本上等于起动温度（Tstart）的温度控制蒸汽的温度完全打开，在起动温度（Tstart）下向蒸汽轮机（5）供应蒸汽。通过根据由蒸汽通过其的控制阀（7）引起的温度下降来控制控制阀（7）上游的蒸汽温度来控制蒸汽温度。

4. 发明申请

US20110103970A1 STEAM TURBINE WITH RELIEF GROOVE ON THE ROTOR 有权
标题翻译：蒸汽涡轮机带有转子上的扶梯
公开(公告)号：US20110103970A1
公开(公告)日：2011-05-05
申请号：US12893761
申请日：2010-09-29
申请人： Rabiye BEKYIGIT , Philipp BRUNNER , Jian CHEN , Rolf DÖBLER , Jozo DRMIC , Andreas EHRSAM , Maurus HERZOG , Davor KRIZ , Thomas MOKULYS , Martin REIGL , Luca RIPAMONTI , Thomas SCHREIER , Giorgio ZANAZZI
发明人： Rabiye BEKYIGIT , Philipp BRUNNER , Jian CHEN , Rolf DÖBLER , Jozo DRMIC , Andreas EHRSAM , Maurus HERZOG , Davor KRIZ , Thomas MOKULYS , Martin REIGL , Luca RIPAMONTI , Thomas SCHREIER , Giorgio ZANAZZI
IPC分类号： F01D5/18
CPC分类号： F01D3/04 , F01D5/06 , F01D5/08 , F01D25/14
摘要： A steam turbine is provided having a relief groove which is arranged in the region of the equalizing piston and extends in the circumferential direction of the rotor. The relief groove, with regard to an inlet passage, is arranged in the axial upstream direction so that it is arranged on the rotor outside a region in which the steam flow enters the bladed flow path via the inlet passage. The relief groove, with regard to the first blade row, is arranged in a region in which the greatest thermal stresses can arise in the rotor. As an option, the relief groove has a cover for reducing vortex flows, and also devices for reducing heating of the groove or devices for active cooling. The steam turbine allows an increased number of risk-free running up and running down operations of the steam turbine with minimum detriment to the turbine performance.
摘要翻译：一种蒸汽轮机，其具有设置在均压活塞的区域中并在转子的圆周方向上延伸的释放槽。相对于入口通道的释放槽布置在轴向上游方向上，使得其在转子的外侧经由入口通道进入叶片流动路径的区域外部。相对于第一叶片排，安全槽布置在转子中可能产生最大热应力的区域中。作为一种选择，该释放槽具有用于减少涡流的盖，以及用于减少用于主动冷却的槽或装置的加热的装置。蒸汽轮机允许蒸汽轮机的无风险运行和运行的次数增加，同时对涡轮机性能的影响最小。

5. 发明申请

US20080213091A1 Steam Turbine 审中-公开
标题翻译：汽轮机
公开(公告)号：US20080213091A1
公开(公告)日：2008-09-04
申请号：US12033091
申请日：2008-02-19
申请人： Heinrich Lageder , Lucjan Lukasik , Ralf Greim , Thomas Schreier , Michael Fischer
发明人： Heinrich Lageder , Lucjan Lukasik , Ralf Greim , Thomas Schreier , Michael Fischer
IPC分类号： F01D9/00 , F01D25/24
CPC分类号： F01D25/26 , F01D25/28 , F05B2260/301 , F05D2220/31 , F05D2230/21 , F05D2230/232 , F05D2230/235 , F05D2240/14
摘要： A steam turbine (10), especially in the form of a double-flow low-pressure steam turbine, includes a rotor (11) which is rotatably mounted around an axis (21) and which is concentrically enclosed with a spacing by an inner casing (13), forming annular steam passages (28, 29), and which has a multiplicity of rotor blades (12) which project into the steam passages (28, 29), wherein the inner casing (13) supports a multiplicity of stator blades (12) which project into the steam passages (28, 29) and which, for feeding steam to the steam passages (28, 29), has an inlet duct (15) which is directed around the axis (21) and tapers in the flow cross section. With such a steam turbine, the production is simplified by the inner casing (13) being formed as a welded construction, in which blade carriers (14), which delimit the steam passages (28, 29) and are produced as cast parts, are welded to additional forged or rolled steel elements (20) for fastening the stator blades (12′).
摘要翻译：特别是双流低压汽轮机形式的蒸汽涡轮机（10）包括转子（11），转子（11）围绕轴线（21）可旋转地安装，同轴地由内壳（13），形成环形蒸汽通道（28,29），并且具有多个突出到所述蒸汽通道（28,29）中的转子叶片（12），其中所述内壳体（13）支撑多个定子叶片（12），其突出到所述蒸汽通道（28,29）中，并且用于将蒸汽供给至所述蒸汽通道（28,29）的入口管道（15）具有围绕所述轴线（21）指向并在流动截面。通过这样的蒸汽涡轮机，通过形成为焊接结构的内壳（13）来简化生产，其中限定蒸汽通道（28,29）并被制成铸件的叶片承载件（14）是焊接到用于紧固定子叶片（12'）的另外的锻造或轧制钢元件（20）。

6. 发明授权

US09140192B2 Startup method for large steam turbines 有权
标题翻译：大型蒸汽轮机的启动方法
公开(公告)号：US09140192B2
公开(公告)日：2015-09-22
申请号：US13347745
申请日：2012-01-11
申请人： Andreas Ehrsam , Thomas Schreier , Martin Schoenenberger
发明人： Andreas Ehrsam , Thomas Schreier , Martin Schoenenberger
IPC分类号： F01D19/00 , F02C7/26 , F01K13/02
CPC分类号： F02C7/26 , F01D19/00 , F01K13/02
摘要： A method of controlling a steam turbine, having a controller controlling at least the position of a steam inlet valve located in a steam conduit between a steam generator and the turbine to control mass flow into the turbine, includes selecting, before beginning startup, a predefined set of startup sequences of setpoints based on a turbine status at the beginning of startup and/or a startup mode chosen by the operator, the set of startup sequences of setpoints includes parameters controlled and not controlled by the controller; using the controller to control the parameters controlled by the controller so as to progress the turbine from setpoint to setpoint in accordance with predefined set of startup sequences until reaching a release point; and at the release point, delaying moving to the next setpoint until actual setpoint values agree with predefined release point setpoint values for parameters not controlled by the controller.
摘要翻译：一种控制蒸汽涡轮机的方法，具有控制器至少控制位于蒸汽发生器和涡轮机之间的蒸汽导管中的蒸汽入口阀的位置，以控制进入涡轮机的质量流量，包括在开始启动之前选择预定义的基于启动开始时的涡轮机状态和/或由操作者选择的启动模式的设定点的启动顺序集合，设定点的启动序列的集合包括由控制器控制和不控制的参数; 使用所述控制器来控制由所述控制器控制的参数，以便根据预定义的启动序列集合将所述涡轮机从设定点进给到设定点，直到达到释放点; 并且在释放点，延迟移动到下一个设定值，直到实际设定值与预定义的释放点设定值一致为参数未被控制器控制。

7. 发明授权

US08684663B2 Steam turbine with relief groove on the rotor 有权
标题翻译：蒸汽轮机带转子上的浮雕槽
公开(公告)号：US08684663B2
公开(公告)日：2014-04-01
申请号：US12893761
申请日：2010-09-29
申请人： Rabiye Bekyigit , Philipp Brunner , Jian Chen , Rolf Dobler , Jozo Drmic , Andreas Ehrsam , Maurus Herzog , Davor Kriz , Thomas Mokulys , Martin Reigl , Luca Ripamonti , Thomas Schreier , Giorgio Zanazzi
发明人： Rabiye Bekyigit , Philipp Brunner , Jian Chen , Rolf Dobler , Jozo Drmic , Andreas Ehrsam , Maurus Herzog , Davor Kriz , Thomas Mokulys , Martin Reigl , Luca Ripamonti , Thomas Schreier , Giorgio Zanazzi
IPC分类号： F01D25/12
CPC分类号： F01D3/04 , F01D5/06 , F01D5/08 , F01D25/14
摘要： A steam turbine is provided having a relief groove which is arranged in the region of the equalizing piston and extends in the circumferential direction of the rotor. The relief groove, with regard to an inlet passage, is arranged in the axial upstream direction so that it is arranged on the rotor outside a region in which the steam flow enters the bladed flow path via the inlet passage. The relief groove, with regard to the first blade row, is arranged in a region in which the greatest thermal stresses can arise in the rotor. As an option, the relief groove has a cover for reducing vortex flows, and also devices for reducing heating of the groove or devices for active cooling. The steam turbine allows an increased number of risk-free running up and running down operations of the steam turbine with minimum detriment to the turbine performance.
摘要翻译：一种蒸汽轮机，其具有设置在均压活塞的区域中并在转子的圆周方向上延伸的释放槽。相对于入口通道的释放槽布置在轴向上游方向上，使得其在转子的外侧经由入口通道进入叶片流动路径的区域外部。相对于第一叶片排，安全槽布置在转子中可能产生最大热应力的区域中。作为一种选择，该释放槽具有用于减少涡流的盖，以及用于减少用于主动冷却的槽或装置的加热的装置。蒸汽轮机允许蒸汽轮机的无风险运行和运行的次数增加，同时对涡轮机性能的影响最小。

8. 发明申请

US20130177388A1 STARTUP METHOD FOR LARGE STEAM TURBINES 有权
标题翻译：大型蒸汽涡轮机的启动方法
公开(公告)号：US20130177388A1
公开(公告)日：2013-07-11
申请号：US13347745
申请日：2012-01-11
申请人： Andreas EHRSAM , Thomas SCHREIER , Martin SCHOENENBERGER
发明人： Andreas EHRSAM , Thomas SCHREIER , Martin SCHOENENBERGER
IPC分类号： F01D19/00
CPC分类号： F02C7/26 , F01D19/00 , F01K13/02
摘要： A method of controlling a steam turbine, having a controller controlling at least the position of a steam inlet valve located in a steam conduit between a steam generator and the turbine to control mass flow into the turbine, includes selecting, before beginning startup, a predefined set of startup sequences of setpoints based on a turbine status at the beginning of startup and/or a startup mode chosen by the operator, the set of startup sequences of setpoints includes parameters controlled and not controlled by the controller; using the controller to control the parameters controlled by the controller so as to progress the turbine from setpoint to setpoint in accordance with predefined set of startup sequences until reaching a release point; and at the release point, delaying moving to the next setpoint until actual setpoint values agree with predefined release point setpoint values for parameters not controlled by the controller.
摘要翻译：一种控制蒸汽涡轮机的方法，具有控制器至少控制位于蒸汽发生器和涡轮机之间的蒸汽导管中的蒸汽入口阀的位置，以控制进入涡轮机的质量流量，包括在开始启动之前选择预定义的基于启动开始时的涡轮机状态和/或由操作者选择的启动模式的设定点的启动顺序集合，设定点的启动序列的集合包括由控制器控制和不控制的参数; 使用所述控制器来控制由所述控制器控制的参数，以便根据预定义的启动序列集合将所述涡轮机从设定点进给到设定点，直到达到释放点; 并且在释放点，延迟移动到下一个设定值，直到实际设定值与预定义的释放点设定值一致为参数未被控制器控制。

9. 外观设计

USD512664S1 Bicycle frame 失效
公开(公告)号：USD512664S1
公开(公告)日：2005-12-13
申请号：US29206657
申请日：2004-06-02
申请人： Thomas Schreier
设计人： Thomas Schreier

10. 发明授权

US08887481B2 Method for starting a combined cycle power plant 有权
标题翻译：启动联合循环发电厂的方法
公开(公告)号：US08887481B2
公开(公告)日：2014-11-18
申请号：US12964982
申请日：2010-12-10
申请人： Andreas Ehrsam , Thomas Schreier
发明人： Andreas Ehrsam , Thomas Schreier
IPC分类号： F02C6/00 , F02G1/00 , F02G3/00 , F01D19/02 , F02C7/26
CPC分类号： F01D19/02 , F02C7/26 , F05D2270/303
摘要： A method for starting a combined cycle power plant (1) includes loading the gas turbine unit (2), providing a starting temperature (Tstart) for the steam supplied to the steam turbine (5), while the control valve (7) is regulated controlling the temperature of the steam at a temperature substantially equal to the starting temperature (Tstart) at a position (P2) downstream of the control valve (7) and upstream of the rotor (8), when the control valve (7) is substantially fully open, supplying steam to the steam turbine (5) at the starting temperature (Tstart). The steam temperature is controlled by controlling the steam temperature upstream of the control valve (7) in accordance with the temperature drop caused by the control valve (7) when the steam passes through it.
摘要翻译：一种启动联合循环发电厂（1）的方法包括加载燃气轮机单元（2），为供给蒸汽轮机（5）的蒸汽提供启动温度（Tstart），同时控制阀（7）被调节当控制阀（7）基本上等于控制阀（7）下游的位置（P2）和转子（8）的上游时，基本上等于起动温度（Tstart）的温度控制蒸汽的温度完全打开，在起动温度（Tstart）下向蒸汽轮机（5）供应蒸汽。通过根据由蒸汽通过其的控制阀（7）引起的温度下降来控制控制阀（7）上游的蒸汽温度来控制蒸汽温度。

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