专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20090076136A1 THERAPEUTIC AGENT 审中-公开
标题翻译：治疗剂
公开(公告)号：US20090076136A1
公开(公告)日：2009-03-19
申请号：US12263809
申请日：2008-11-03
申请人： Tatsuji ENOKI , Eiji Kobayashi , Kinuko Ogawa , Yoko Kudo , Masashige Tanabe , Hiromu Ohnogi , Hiroaki Sagawa , Ikunoshin Kato
发明人： Tatsuji ENOKI , Eiji Kobayashi , Kinuko Ogawa , Yoko Kudo , Masashige Tanabe , Hiromu Ohnogi , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号： A61K31/343 , A61K31/225 , A61K31/19 , A61K31/192 , A61K31/11 , A61P3/04 , A61P3/10
CPC分类号： A61K31/11 , A23K20/00 , A23L33/10
摘要： The present invention relates to a therapeutic agent or prophylactic agent for a disease accompanying an abnormality in an amount of insulin or insulin response, an insulin-mimetic action agent, a food, beverage, or feed, an agent for enhancement of glucose uptake into a cell, and an agent for inducing differentiation into an adipocyte, each comprising as an effective ingredient at least one compound selected from the group consisting of specified compounds having an insulin-mimetic action, derivatives thereof, and pharmacologically acceptable salts thereof.
摘要翻译：本发明涉及一种伴随胰岛素或胰岛素反应量异常的疾病的治疗剂或预防剂，胰岛素模拟作用剂，食物，饮料或饲料，用于增强葡萄糖摄入细胞和用于诱导分化成脂肪细胞的药剂，其各自包含至少一种选自具有胰岛素模拟作用的特定化合物，其衍生物和其药理学上可接受的盐的至少一种化合物作为有效成分。

2. 发明授权

US07498357B2 Chalcone compounds 失效
标题翻译：查耳酮化合物
公开(公告)号：US07498357B2
公开(公告)日：2009-03-03
申请号：US10581034
申请日：2004-12-01
申请人： Hiromu Ohnogi , Katsumi Sugiyama , Tatsuji Enoki , Eiji Kobayashi , Hiroaki Sagawa , Ikunoshin Kato
发明人： Hiromu Ohnogi , Katsumi Sugiyama , Tatsuji Enoki , Eiji Kobayashi , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号： A61K31/343 , C07D307/80
CPC分类号： C07D493/08 , A23K20/121 , A23L33/10 , C07C49/835 , C07C49/84 , C07C409/08 , C07D307/80
摘要： The present invention provides a novel chalcone compound, its derivative or a salt thereof, each having a suppressive action of NO production or an inhibitory action of aldose reductase. In addition, the present invention provides a medicament, a food, a beverage or a feed having a therapeutic or prophylactic effect for a disease showing sensitivity to the compound, by utilizing the physiological actions of the compound.
摘要翻译：本发明提供了具有NO产生抑制作用或醛糖还原酶抑制作用的新型查耳酮化合物及其衍生物或其盐。此外，本发明通过利用化合物的生理作用，提供对化合物显示敏感性的疾病具有治疗或预防作用的药物，食品，饮料或饲料。

3. 发明申请

US20070092587A1 Extract from plant of japanese parsley family and process for producing the same 审中-公开
标题翻译：从日本欧芹系列植物提取物及其生产方法
公开(公告)号：US20070092587A1
公开(公告)日：2007-04-26
申请号：US10561431
申请日：2004-06-18
申请人： Hiromu Ohnogi , Katsumi Sugiyama , Nobuko Muraki , Tatsuji Enoki , Hiroaki Sagawa , Ikunoshin Kato
发明人： Hiromu Ohnogi , Katsumi Sugiyama , Nobuko Muraki , Tatsuji Enoki , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号： A61K36/232
CPC分类号： A61K36/232 , A23L2/02 , A23V2002/00 , A23V2250/21 , A23V2200/328
摘要： The present invention provides an extract obtainable by extracting a plant belonging to Umbelliferae, or a processed product thereof, with a water-containing alcohol; a process for preparing the extract; a therapeutic agent or prophylactic agent for a disease accompanying an abnormality in an amount of insulin or insulin response and/or diabetic complications, characterized in that the therapeutic agent or prophylactic agent comprises as an effective ingredient the extract as defined above; an agent for an insulin-mimetic action, characterized in that the agent comprises as an effective ingredient the extract as defined above; a food, beverage or feed, comprising the extract as defined above; an agent for enhancing glucose uptake into a cell, characterized in that the agent comprises as an effective ingredient the extract as defined above; to an agent for inducing differentiation into an adipocyte, characterized in that the agent comprises as an effective ingredient the extract as defined above; and an inhibitory agent for aldose reductase, characterized in that the agent comprises as an effective ingredient the extract as define above.
摘要翻译：本发明提供通过用含水醇提取属于伞形赤霉属的植物或其加工产物而获得的提取物; 一种制备提取物的方法; 用于伴随胰岛素或胰岛素反应量和/或糖尿病并发症的异常的疾病的治疗剂或预防剂，其特征在于所述治疗剂或预防剂包含作为有效成分的上述提取物; 用于胰岛素模拟作用的药剂，其特征在于所述药剂包含如上所定义的提取物作为有效成分; 包含上述提取物的食品，饮料或饲料; 用于增强葡萄糖摄入细胞的药剂，其特征在于所述药剂包含如上所定义的提取物作为有效成分; 涉及诱导分化为脂肪细胞的药剂，其特征在于所述药剂包含如上所定义的提取物作为有效成分; 以及醛糖还原酶抑制剂，其特征在于，所述药剂含有作为有效成分的上述定义的提取物。

4. 发明申请

US20060216362A1 Remedy 审中-公开
标题翻译：补救
公开(公告)号：US20060216362A1
公开(公告)日：2006-09-28
申请号：US10557184
申请日：2004-05-14
申请人： Tatsuji Enoki , Kinuko Ogawa , Hiromu Ohnogi , Nobuko Muraki , Yoko Kudo , Hiroaki Sagawa , Ikunoshin Kato
发明人： Tatsuji Enoki , Kinuko Ogawa , Hiromu Ohnogi , Nobuko Muraki , Yoko Kudo , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号： A61K36/9066 , A61K36/886 , A61K36/282 , A61K36/28 , A61K36/704 , A61K36/185
CPC分类号： A61K36/896 , A23K20/10 , A23L33/105 , A61K36/185 , A61K36/28 , A61K36/282 , A61K36/287 , A61K36/70 , A61K36/704 , A61K36/886 , A61K36/906 , A61K36/9066
摘要： The present invention relates to a therapeutic agent and prophylactic agent for a disease accompanying an abnormality in an amount of insulin or insulin response, an agent for an insulin-mimetic action, a food, beverage and feed for treating a preventing a disease accompanying an abnormality in an amount of insulin or insulin response, an agent for enhancing glucose uptake into a cell, and an agent for inducing differentiation into an adipocyte, characterized in that each comprises as an effective ingredient a processed product derived from at least one plant selected from the group consisting of (a) a plant belonging to Tiliaceae, (b) a plant belonging to Zingiberaceae, (c) a plant belonging to Compositae, (d) a plant belonging to Liliaceae, and (e) a plant belonging to Polygonaceae.
摘要翻译：本发明涉及一种伴随胰岛素或胰岛素反应量异常的疾病的治疗剂和预防剂，用于胰岛素模拟作用的药物，用于治疗预防伴随异常的疾病的食品，饮料和饲料一定量的胰岛素或胰岛素反应，用于增强葡萄糖摄入细胞的药剂和用于诱导分化成脂肪细胞的药剂，其特征在于每种药物包含作为有效成分的来自至少一种选自以下的植物的加工产品：（a）属于尖嘴科的植物，（b）属于姜科的植物，（c）属于菊科的植物，（d）属于百合科的植物，和（e）属于Poly科的植物。

5. 发明授权

US06911432B2 Drugs, foods or drinks with the use of algae-derived physiologically active substances 失效
标题翻译：使用藻类来源的生理活性物质的药物，食品或饮料
公开(公告)号：US06911432B2
公开(公告)日：2005-06-28
申请号：US10228195
申请日：2002-08-27
申请人： Tatsuji Enoki , Hiroaki Sagawa , Takanari Tominaga , Eiji Nishiyama , Nobuto Koyama , Takeshi Sakai , Fu-Gong Yu , Katsushige Ikai , Ikunoshin Kato
发明人： Tatsuji Enoki , Hiroaki Sagawa , Takanari Tominaga , Eiji Nishiyama , Nobuto Koyama , Takeshi Sakai , Fu-Gong Yu , Katsushige Ikai , Ikunoshin Kato
IPC分类号： A23L1/30 , A23L3/3472 , A23L3/3544 , A23L3/3562 , A61K31/341 , C07G99/00 , A01N43/04
CPC分类号： A01N43/04 , A23L3/3472 , A23L3/3544 , A23L3/3562 , A23L33/105 , A61K31/341 , A61K31/7048
摘要： Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose are represented by formula (I): These compositions include foods, drinks, cosmetics, etc. containing as the active ingredient at least one such compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. These compounds show an apoptosis-inducing activity, carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes them useful also as the active ingredient of antioxidants and preservatives.
摘要翻译：用于治疗，改善或预防对3,6-脱水吡喃半乳糖敏感的疾病的药物组合物由式（I）表示：这些组合物包括含有至少一种这样的化合物，其醛，其水合物和2-O-甲基化衍生物和含有上述化合物的可溶性糖化合物。这些化合物对活性氧，脂质过氧化物自由基和NO的生成表现出细胞凋亡诱导活性，制癌活性和抑制活性，这使得它们也可用作抗氧化剂和防腐剂的活性成分。

6. 发明授权

US06482806B1 Product of heat treatment of uronic acid, food, drink, or drug including the product 失效
标题翻译：糖醛酸，食品，饮料或药品的热处理产品，包括产品
公开(公告)号：US06482806B1
公开(公告)日：2002-11-19
申请号：US09125397
申请日：1998-08-18
申请人： Nobuto Koyama , Hiroaki Sagawa , Eiji Kobayashi , Tatsuji Enoki , Hua-Kang Wu , Eiji Nishiyama , Suzu Deguchi , Katsushige Ikai , Hiromu Ohnogi , Motoko Ueda , Akihiro Kondo , Ikunoshin Kato
发明人： Nobuto Koyama , Hiroaki Sagawa , Eiji Kobayashi , Tatsuji Enoki , Hua-Kang Wu , Eiji Nishiyama , Suzu Deguchi , Katsushige Ikai , Hiromu Ohnogi , Motoko Ueda , Akihiro Kondo , Ikunoshin Kato
IPC分类号： A61K31727
CPC分类号： C07H7/033 , A61K8/60 , A61Q11/00 , Y10S977/928 , Y10S977/929 , Y10S977/93
摘要： A product obtained by heating at least one substance selected from the following (a), (b) and (c). (a) uronic acid or uronic acid derivative; (b) a saccharide compound containing uronic acid or a saccharide compound containing uronic acid derivative; and (c) a substance containing a saccharide compound containing uronic acid or a substance containing a saccharide compound containing uronic acid derivative; and food, beverage or a pharmaceutical agent which is characterized in containing the above-mentioned heat-treated product.
摘要翻译：通过加热选自以下（a），（b）和（c）中的至少一种物质获得的产物：（a）糖醛酸或糖醛酸衍生物;（b）含有糖醛酸或含有糖醛酸的糖类化合物的糖类化合物酸衍生物; 和（c）含有糖醛酸的糖类化合物或含有糖醛酸衍生物的糖类化合物的物质的物质;以及含有上述热处理物的食品，饮料或药剂。

7. 发明授权

US06475990B1 Drugs, foods or drinks with the use of algae-derived physiologically active substances 失效
标题翻译：使用藻类来源的生理活性物质的药物，食品或饮料
公开(公告)号：US06475990B1
公开(公告)日：2002-11-05
申请号：US09554235
申请日：2000-05-11
申请人： Tatsuji Enoki , Hiroaki Sagawa , Takanari Tominaga , Eiji Nishiyama , Nobuto Koyama , Takeshi Sakai , Fu-Gong Yu , Katsushige Ikai , Ikunoshin Kato
发明人： Tatsuji Enoki , Hiroaki Sagawa , Takanari Tominaga , Eiji Nishiyama , Nobuto Koyama , Takeshi Sakai , Fu-Gong Yu , Katsushige Ikai , Ikunoshin Kato
IPC分类号： A01N4304
CPC分类号： A01N43/04 , A23L3/3472 , A23L3/3544 , A23L3/3562 , A23L33/105 , A61K31/341 , A61K31/7048
摘要： Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.
摘要翻译：用于治疗，改善或预防对由式（1）表示的3,6-脱水吡喃半乳糖敏感的疾病的药物组合物：含有作为活性成分的至少一种选自上述组分的组分的食品，饮料，化妆品等，所述化合物，其醛，其水合物和2-O-甲基化衍生物以及含有上述化合物的可溶性糖化合物。该化合物还显示例如细胞凋亡诱导活性，制癌活性和对活性氧，脂质过氧化物自由基和NO的产生的抑制活性，这使得它也可用作抗氧化剂和防腐剂的活性成分。

8. 发明授权

US06177592B1 Compounds 失效
标题翻译：化合物
公开(公告)号：US06177592B1
公开(公告)日：2001-01-23
申请号：US09341768
申请日：1999-07-16
申请人： Nobuto Koyama , Tatsuji Enoki , Katsushige Ikai , Hua-Kang Wu , Hiromu Ohnogi , Takanari Tominaga , Eiji Nishiyama , Michio Hagiya , Hiroaki Sagawa , Hideto Chono , Ikunoshin Kato
发明人： Nobuto Koyama , Tatsuji Enoki , Katsushige Ikai , Hua-Kang Wu , Hiromu Ohnogi , Takanari Tominaga , Eiji Nishiyama , Michio Hagiya , Hiroaki Sagawa , Hideto Chono , Ikunoshin Kato
IPC分类号： C07C6106
CPC分类号： C07C323/59 , A23K20/105 , A23L2/52 , A23L33/10 , A23V2002/00 , A61K31/122 , C07C45/60 , C07C45/78 , C07C49/707 , C07C323/58 , C07C2601/08 , Y02A50/478 , A23V2200/224 , A23V2250/5026 , A23V2250/5024 , A23V2250/70 , A23V2250/204 , A23V2250/06 , A23V2250/21
摘要： A compound represented by the following formula [I] or an optically active substance or a salt thereof. (In the formula, a bond shown by a dotted line in the five-membered ring means that said five-membered ring may be any of a cyclopentene ring having a double bond and a cyclopentane ring where said bond is saturated and, in the case of a cyclopentene ring, X is OH, Y is ═O and Z is H while, in the case of a cyclopentane ring, X is ═O, Y is OH and Z is OH. R is a residue after removal of an SH group from the SH-containing compound.)
摘要翻译：由下式[I]表示的化合物或光学活性物质或其盐（在该式中，五元环中虚线所示的键表示所述五元环可以是具有双键的环戊烯环和所述键饱和的环戊烷环，在环戊烯环的情况下，X为OH，Y为= O且Z为H，而在环戊烷环的情况下，X为= O，Y是OH，Z是OH，R是从含SH的化合物除去SH基团后的残基。

9. 发明授权

US6166091A 2,3,4-trihydroxycyclopentanone 失效
标题翻译： 2,3,4-三羟基环戊酮
公开(公告)号：US6166091A
公开(公告)日：2000-12-26
申请号：US402086
申请日：1999-09-29
申请人： Kaoru Kojima , Katsushige Ikai , Tatsuji Enoki , Nobuto Koyama , Ikunoshin Kato
发明人： Kaoru Kojima , Katsushige Ikai , Tatsuji Enoki , Nobuto Koyama , Ikunoshin Kato
IPC分类号： C07C45/48 , C07C45/59 , C07C45/64 , C07C49/493 , A61K31/122 , C07C49/297
CPC分类号： C07C49/493 , C07C45/48 , C07C45/59 , C07C45/64
摘要： 2,3,4-trihydroxycyclopentanone represented by the following formula [I], its optically active substance or salt thereof. ##STR1##
摘要翻译： PCT No.PCT / JP98 / 02425 Sec。 371 1999年9月29日第 102（e）1999年9月29日PCT PCT 1998年6月1日PCT公布。第WO98 / 56745号公报日本12月17日，19982,3,4三羟基环戊酮由下式[I]表示，其光学活性物质或其盐。

10. 发明授权

US6087401A Cyclopentenones, process for preparing the same, and the use thereof 失效
标题翻译：环戊烯酮，其制备方法及其用途
公开(公告)号：US6087401A
公开(公告)日：2000-07-11
申请号：US230868
申请日：1999-02-02
申请人： Nobuto Koyama , Hiroaki Sagawa , Eiji Kobayashi , Tatsuji Enoki , Hua-Kang Wu , Eiji Nishiyama , Katsushige Ikai , Ikunoshin Kato
发明人： Nobuto Koyama , Hiroaki Sagawa , Eiji Kobayashi , Tatsuji Enoki , Hua-Kang Wu , Eiji Nishiyama , Katsushige Ikai , Ikunoshin Kato
IPC分类号： A23L1/30 , A61K8/35 , A61K8/60 , A61K31/12 , A61Q5/00 , A61Q11/00 , A61Q19/00 , C07C45/67 , C07C49/707 , C07H7/033
CPC分类号： C07H7/033 , A61K8/35 , A61K8/60 , A61Q17/005 , A61Q19/00 , A61Q11/00 , A61Q19/10 , A61Q5/00
摘要： There is disclosed a method of manufacturing 4,5-dihydroxy-2-cyclopenten-1-one represented by the following formula [1] which is characterized in that at least one substance selected from the following (a), (b) and (c) is heated.(a): uronic acid or uronic acid derivative(s);(b): a saccharide compound which contains uronic acid and/or uronic acid derivative(s); and(c): a substance containing a saccharide compound which contains uronic acid and/or uronic acid derivative(s). ##STR1##
摘要翻译： PCT No.PCT / JP97 / 03052 Sec。 371日期1999年2月2日 102（e）1999年2月2日PCT 1997年9月1日PCT PCT。公开号WO98 / 13328 日期：1998年4月2日公开了由下式[1]表示的4,5-二羟基-2-环戊烯-1-酮的制造方法，其特征在于，选自下述（a），（b）和（c）被加热。（a）：糖醛酸或糖醛酸衍生物; （b）：含有糖醛酸和/或糖醛酸衍生物的糖类化合物; 和（c）：含有糖醛酸和/或糖醛酸衍生物的糖类化合物的物质。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式