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1. 发明申请

US20060166335A1 Glucuronofucan sulfate 审中-公开
公开(公告)号：US20060166335A1
公开(公告)日：2006-07-27
申请号：US11373989
申请日：2006-03-14
申请人： Takeshi Sakai , Kumiko Ishizuka , Kaoru Kojima , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
发明人： Takeshi Sakai , Kumiko Ishizuka , Kaoru Kojima , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
IPC分类号： C12P19/04 , C12N9/24
CPC分类号： C12Y302/01139 , C08B37/00 , C08B37/006 , C12N9/2402 , C12P19/14 , C12R1/01 , C12Y302/01044
摘要： Three enzymes degrading sulfated glucuronofucan; processes for producing these enzymes; activators for these enzymes; glucuronofucan sulfate and degradation products thereof; and a novel microorganism.

2. 发明授权

US06593311B2 Apoptosis inducers 失效
标题翻译：凋亡诱导剂
公开(公告)号：US06593311B2
公开(公告)日：2003-07-15
申请号：US09770504
申请日：2001-01-29
申请人： Takeshi Sakai , Hideo Kitano , Fu-Gong Yu , Shinji Nakayama , Kaoru Kojima , Hitomi Kimura , Yoshikuni Nakanishi , Kaoru Katayama , Takanari Tominaga , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
发明人： Takeshi Sakai , Hideo Kitano , Fu-Gong Yu , Shinji Nakayama , Kaoru Kojima , Hitomi Kimura , Yoshikuni Nakanishi , Kaoru Katayama , Takanari Tominaga , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
IPC分类号： A61K31715
CPC分类号： C12Y302/01078 , A61K31/737 , C12N9/2494 , C12P19/14 , C12Y302/01044
摘要： Apoptosis inducers, anticancer drugs and carcinostatic drugs containing sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof, and a method for inducing apoptosis by using sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof as the active ingredient. A degrading enzyme which is useful in the production of the degradation products of sulfated-fucose-containing polysaccharides.
摘要翻译：含有硫酸化岩藻糖的多糖和/或其降解产物的细胞凋亡诱导剂，抗癌药和抗癌药以及使用含有硫酸化岩藻糖的多糖和/或降解产物诱导细胞凋亡的方法作为活性成分。一种可用于生产含硫酸化岩藻糖多糖的降解产物的降解酶。

3. 发明授权

US06379947B2 Biologically pure culture of Fucoidanobacter marinus SI-0098 (FERM BP-5403) 失效
标题翻译：岩藻多糖杆菌SI-0098（FERM BP-5403）的生物纯培养物
公开(公告)号：US06379947B2
公开(公告)日：2002-04-30
申请号：US09893620
申请日：2001-06-29
申请人： Takeshi Sakai , Hitomi Kimura , Kaoru Kojima , Katsushige Ikai , Sumiko Akiyoshi , Yoshikuni Nakanishi , Ikunoshin Kato
发明人： Takeshi Sakai , Hitomi Kimura , Kaoru Kojima , Katsushige Ikai , Sumiko Akiyoshi , Yoshikuni Nakanishi , Ikunoshin Kato
IPC分类号： C12N112
CPC分类号： C12Y302/01044 , C07H1/00 , C07H3/06 , C07H5/10 , C12N9/2402 , C12N9/88 , C12P19/44 , C12R1/01 , Y10S435/822
摘要： A novel endo-fucoidan-lyase and a novel microorganism, Fucoidanobacter marinus SI-0098 (FERM BP-5403) useful in the production of sugar compounds are disclosed Sugar compounds represented by the following general formula (1), wherein at least one of alcoholic hydroxyl group has been sulfated, or salts thereof: wherein Y represents hydrogen or a group represented by the following formula (2).
摘要翻译：公开了一种可用于生产糖化合物的新型内切 - 岩藻依聚糖裂解酶和新型微生物，岩藻多糖杆菌SI-0098（FERM BP-5403），由以下通式（1）表示，其中至少一种醇羟基已被硫酸化，或其盐：其中Y表示氢或由下式（2）表示的基团。

4. 发明授权

US06720419B2 Sulfated fucan oligosaccharide 失效
标题翻译：硫酸化的fucan寡糖
公开(公告)号：US06720419B2
公开(公告)日：2004-04-13
申请号：US10278942
申请日：2002-10-24
申请人： Takeshi Sakai , Hitomi Amarume , Takashi Kawai , Kaoru Kojima , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
发明人： Takeshi Sakai , Hitomi Amarume , Takashi Kawai , Kaoru Kojima , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
IPC分类号： C08B3700
CPC分类号： C08B37/006
摘要： A smaller molecule obtainable by allowing a sulfated fucan-digesting enzyme which digests a novel sulfated polysaccharide derived from an alga belonging to Laminariales to act on a sulfated fucan, and a method for producing the same.
摘要翻译：通过使来自属于层状藻酸盐的藻类的新型硫酸化多糖消化的硫酸化的岩藻糖消化酶作用于硫酸化的岩藻石上的小分子及其制造方法。

5. 发明授权

US06590097B1 Sulfated fucogalactan 失效
标题翻译：硫酸岩藻糖
公开(公告)号：US06590097B1
公开(公告)日：2003-07-08
申请号：US09913599
申请日：2001-08-16
申请人： Takeshi Sakai , Hitomi Kimura , Kaoru Kojima , Kaoru Katayama , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
发明人： Takeshi Sakai , Hitomi Kimura , Kaoru Kojima , Kaoru Katayama , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
IPC分类号： C08B3700
CPC分类号： C08B37/006 , C12N9/2402 , C12P19/04
摘要： Sulfated fucogalactan or its salt useful as a reagent for sugar chain engineering or an HGF-production inducer; a degraded product or its salt obtained by treating the sulfated fucogalactan with a sulfated fucogalactan digesting enzyme; the sulfated fucogalactan digesting enzyme useful in sugar chain engineering; a process for producing the degraded product by treating sulfated fucogalactan or its salt with the above enzyme; and a process for producing the sulfated fucogalactan digesting enzyme.
摘要翻译：硫酸化的赖卡半乳糖或其盐可用作糖链工程或HGF生产诱导剂的试剂; 通过用硫酸化的福卡美凝乳消化酶处理硫酸化的核糖乳聚糖获得的降解产物或其盐; 用于糖链工程的硫酸岩藻糖半乳糖消化酶; 通过用上述酶处理硫酸化的赖氨酰半乳糖或其盐来生产降解产物的方法; 以及生产硫酸化的赖卡半乳聚糖消化酶的方法。

6. 发明授权

US6054577A Oligosaccharides from enzymatic cleavage of fucoidan 失效
标题翻译：寡核糖从岩藻多糖的酶切割
公开(公告)号：US6054577A
公开(公告)日：2000-04-25
申请号：US930002
申请日：1997-09-26
申请人： Takeshi Sakai , Hitomi Kimura , Kaoru Kojima , Katsushige Ikai , Sumiko Akiyoshi , Yoshikuni Nakanishi , Ikunoshin Kato
发明人： Takeshi Sakai , Hitomi Kimura , Kaoru Kojima , Katsushige Ikai , Sumiko Akiyoshi , Yoshikuni Nakanishi , Ikunoshin Kato
IPC分类号： C07H11/00 , C07H1/00 , C07H3/06 , C07H5/10 , C08B37/00 , C12N1/20 , C12N9/24 , C12N9/88 , C12P19/14 , C12P19/44 , C07H13/02 , C12P19/04
CPC分类号： C12Y302/01044 , C07H1/00 , C07H3/06 , C07H5/10 , C12N9/2402 , C12N9/88 , C12P19/44 , C12R1/01 , Y10S435/822
摘要： A novel endo-fucoidan-lyase and a novel microorganism useful in the production of sugar compounds. Sugar compounds represented by the following general formula (1), wherein at least one of alcoholic hydroxyl group has been sulfated, or salts thereof: ##STR1## wherein Y represents hydrogen or a group represented by the following formula (2). ##STR2##
摘要翻译： PCT No.PCT / JP96 / 01080 Sec。 371日期：1997年9月26日 102（e）1997年9月26日PCT PCT 1996年4月22日PCT公布。公开号WO96 / 34004 日期1996年10月31日一种新型内切 - 岩藻依聚糖裂解酶和用于生产糖化合物的新型微生物。由以下通式（1）表示的糖化合物，其中醇羟基中的至少一个已被硫酸化，或其盐：其中Y表示氢或由下式（2）表示的基团。

7. 发明授权

US07517555B2 Copper plating solution and method for copper plating 有权
标题翻译：镀铜液及镀铜方法
公开(公告)号：US07517555B2
公开(公告)日：2009-04-14
申请号：US10474210
申请日：2002-04-26
申请人： Fumiaki Kikui , Kaoru Kojima , Yoriyoshi Oooka , Kohshi Yoshimura
发明人： Fumiaki Kikui , Kaoru Kojima , Yoriyoshi Oooka , Kohshi Yoshimura
IPC分类号： B05D7/00 , B05D1/18 , C23C18/38 , C23C18/40
CPC分类号： C25D5/34 , C23C18/38 , C25D3/38 , H01F41/026
摘要： A copper plating solution according to the present invention is characterized by that it comprising 0.03 mol/L to 0.5 mol/L of copper sulfate, 0.05 mol/L to 0.7 mol/L of ethylenediaminetetraacetic acid and 0.02 mol/L to 0.3 mol/L of sulfite, and has a pH adjusted to 5.0 to 8.5. A method for copper plating according to the present invention is characterized by that it comprises using the copper plating solution above. The copper plating solution and the method for copper plating according to the present invention stably provide a uniform copper plating film excellent in adhesion on the surface of an article to be plated, such as rare earth metal-based permanent magnet.
摘要翻译：本发明的镀铜液的特征在于，其中含有0.03mol / L〜0.5mol / L的硫酸铜，0.05mol / L〜0.7mol / L的乙二胺四乙酸和0.02mol / L〜0.3mol / L 的亚硫酸盐，并且将pH调节至5.0至8.5。根据本发明的镀铜方法的特征在于其包括使用上述镀铜溶液。根据本发明的镀铜溶液和镀铜方法稳定地提供了在诸如稀土金属基永磁体的待镀制品表面上的粘合性优异的均匀的镀铜膜。

8. 发明授权

US06987081B2 Painted metal sheet for printing with a sublimation dye 有权
标题翻译：用升华染料印刷的金属板
公开(公告)号：US06987081B2
公开(公告)日：2006-01-17
申请号：US10748417
申请日：2003-12-30
申请人： Masaki Sato , Kaoru Kojima , Seiju Suzuki , Kazuhiko Takahashi , Hiroshi Entani
发明人： Masaki Sato , Kaoru Kojima , Seiju Suzuki , Kazuhiko Takahashi , Hiroshi Entani
IPC分类号： B41M5/035 , B41M5/38
CPC分类号： B41M5/0355 , B41M5/41 , B41M5/42 , B41M5/52 , B41M5/5227 , B41M5/5272 , Y10T428/24917 , Y10T428/259
摘要： A colored metal sheet useful as a decorative member, a multi-colored signboard, etc. is provided by transfer-printing a topcoat or clear paint layer 4 formed on a substrate metal sheet 1 with a sublimation dye. A basecoat paint layer 2 and a primer paint layer 3 may be formed between the substrate metal sheet 1 and the paint layer 4. A sublimation dye penetrates into the paint layer 4 to form colored parts 5 extending along thickness direction of the paint layer 4. Glass flakes 6 (of 8 μm or less in thickness and 10-70 μm in length) and calcium silicate (of 1-8 μm in primary particle size) may be dispersed in the paint layer 4, to improve slippage-proof property and wear-resistance. Powdery silica (of 0.5-8 μm in particle size) may be dispersed in the paint layer 4, to improve anti-scratching property and wear-resistance. Light-resistance of the paint layer 4 is improved by using a topcoat or clear paint mainly composed of a melamine-containing thermosetting polyester resin having number average molecular weight of 1000-10000 and a glass transition temperature (Tg) of 20-60° C.
摘要翻译：通过转印印刷形成在基板金属片1上的顶涂层或透明涂料层4，可以用升华染料提供用作装饰件，多色招牌等的有色金属片。可以在基材金属片1和涂料层4之间形成底涂层2和底漆涂料层3。升华染料渗透到涂料层4中，形成沿涂料层4的厚度方向延伸的着色部分5。玻璃片6（厚度为8μm或更小，长度为10-70μm）和硅酸钙（一次粒径为1-8μm）可以分散在涂料层4中，以提高防滑性和耐磨性 -抵抗性。粉末二氧化硅（粒径为0.5-8μm）可以分散在涂料层4中，以提高抗划伤性和耐磨性。通过使用主要由数均分子量为1000〜10000，玻璃化转变温度（Tg）为20〜60℃的含三聚氰胺的热固性聚酯树脂构成的面漆或透明涂料，改善了涂料层4的耐光性。

9. 发明授权

US06207652B1 Apoptosis inducers 失效
公开(公告)号：US06207652B1
公开(公告)日：2001-03-27
申请号：US09051284
申请日：1998-04-09
申请人： Takeshi Sakai , Hideo Kitano , Fu-Gong Yu , Shinji Nakayama , Kaoru Kojima , Hitomi Kimura , Yoshikuni Nakanishi , Kaoru Katayama , Takanari Tominaga , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
发明人： Takeshi Sakai , Hideo Kitano , Fu-Gong Yu , Shinji Nakayama , Kaoru Kojima , Hitomi Kimura , Yoshikuni Nakanishi , Kaoru Katayama , Takanari Tominaga , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
IPC分类号： A61K31715
CPC分类号： C12Y302/01078 , A61K31/737 , C12N9/2494 , C12P19/14 , C12Y302/01044
摘要： Apoptosis inducers, anticancer drugs and carcinostatic drugs containing sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof, and a method for inducing apoptosis by using sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof as the active ingredient. A degrading enzyme which is useful in the production of the degradation products of sulfated-fucose-containing polysaccharides.

10. 发明授权

US07125984B2 Glucuronofucan sulfate 失效
公开(公告)号：US07125984B2
公开(公告)日：2006-10-24
申请号：US10258133
申请日：2001-04-19
申请人： Takeshi Sakai , Kumiko Ishizuka , Kaoru Kojima , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
发明人： Takeshi Sakai , Kumiko Ishizuka , Kaoru Kojima , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
IPC分类号： C08B37/00 , C12P19/04
CPC分类号： C12Y302/01139 , C08B37/00 , C08B37/006 , C12N9/2402 , C12P19/14 , C12R1/01 , C12Y302/01044
摘要： Three enzymes degrading sulfated glucuronofucan; processes for producing these enzymes; activators for these enzymes; glucuronofucan sulfate and degradation products thereof; and a novel microorganism.

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