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1. 发明申请

WO2008121880A2 ADJUSTABLE ANNULOPLASTY RING AND ACTIVATION SYSTEM 审中-公开
标题翻译：可调节的静脉环和活动系统
公开(公告)号：WO2008121880A2
公开(公告)日：2008-10-09
申请号：PCT/US2008/058757
申请日：2008-03-28
申请人： MICARDIA CORPORATION , SHAOLIAN, Samuel, M. , LE, Le , FLORES, Jesus , TRAN, Jason
发明人： SHAOLIAN, Samuel, M. , LE, Le , FLORES, Jesus , TRAN, Jason
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61F2/2448 , A61F2/2466 , A61F2250/0001 , A61F2250/0004
摘要： An adjustable annuloplasty device is described. In some embodiments, the device includes a body member having a surface that conforms at least partially to a cardiac valve annulus. The body member comprises a shape-memory member that transforms from a first configuration to a second configuration in response to an applied energy. In some embodiments, the device further includes a first electrode assembly, coupled to the shape-memory member, that transfers energy to the shape-memory member, and a second electrode assembly, coupled to the shape-memory member, that transfers at least a portion of the energy away from the shape-memory member.
摘要翻译：描述了可调环形成形术装置。在一些实施例中，该装置包括主体构件，其具有至少部分地与心脏瓣膜环相一致的表面。身体构件包括形状记忆构件，其响应于所施加的能量而从第一构型变换到第二构造。在一些实施例中，该装置还包括耦合到形状记忆构件的第一电极组件，其将能量传递到形状记忆构件，以及耦合到形状记忆构件的第二电极组件，其传送至少一个部分能量远离形状记忆部件。

2. 发明申请

WO2007111972A3 ACTIVATION DEVICE FOR DYNAMIC RING MANIPULATION 审中-公开
标题翻译：用于动态环控制的激活装置
公开(公告)号：WO2007111972A3
公开(公告)日：2008-08-07
申请号：PCT/US2007007194
申请日：2007-03-23
申请人： MICARDIA CORP , SHAOLIAN SAMUEL , TRAN JASON , MOADDEB SHAHRAM , BUCHBINDER MAURICE , ZARBATANY DAVID
发明人： SHAOLIAN SAMUEL , TRAN JASON , MOADDEB SHAHRAM , BUCHBINDER MAURICE , ZARBATANY DAVID
IPC分类号： A61N1/00
CPC分类号： A61F2/2445 , A61F2/2466 , A61F2250/0001
摘要： An activation device for applying energy to an implanted annuloplasty ring is described. The activation device includes an outer elongate member having an outer elongate member distal end and an outer elongate member proximal end, and a lumen therebetween, wherein the inner elongate member is slidably insertable through the lumen of the outer member. The activation device further includes at least one adjustable spline having spline proximal and spline distal ends, the spline distal end connected to the inner tubular member distal end and the spline proximal end connected to the outer tubular member distal end, wherein the adjustable spline is configured to flex as the inner tubular member distal end is drawn proximally toward the outer tubular member distal end while the inner elongate member resides in the lumen of the outer elongate member. The activation device further includes at least one energy-transfer element coupled to the adjustable spline.
摘要翻译：描述了一种用于向植入的瓣膜成形术环施加能量的激活装置。激活装置包括具有外部细长构件远端和外部细长构件近端的外部细长构件和其间的内腔，其中内部细长构件可滑动地插入通过外部构件的内腔。激活装置还包括具有花键近端和花键远端的至少一个可调节花键，所述花键远端连接到内管状构件远端，花键近端连接到外管状构件远端，其中可调节花键配置当内部细长构件位于外部细长构件的内腔中时，内部管状构件远端朝向外侧管状构件远端被拉近。激活装置还包括耦合到可调节花键的至少一个能量传递元件。

3. 发明申请

WO2009023590A1 ADJUSTABLE ANNULOPLASTY RING AND ACTIVATION SYSTEM 审中-公开
标题翻译：可调节的静脉环和活动系统
公开(公告)号：WO2009023590A1
公开(公告)日：2009-02-19
申请号：PCT/US2008/072688
申请日：2008-08-08
申请人： MICARDIA CORPORATION , LE, Le , TRAN, Jason , FLORES, Jesus , MAC, Kelly
发明人： LE, Le , TRAN, Jason , FLORES, Jesus , MAC, Kelly
IPC分类号： A61F2/24
CPC分类号： A61F2/2448 , A61B18/1492 , A61B18/18 , A61B18/20 , A61B2017/00867 , A61B2018/00821 , A61B2218/002 , A61F2/2445 , A61F2210/0038 , A61F2250/0001 , A61F2250/0004 , C08L2201/12
摘要： An adjustable implantable medical device and adjustment device are described. In some embodiments, the adjustment device includes a lead with a distal end modified to permit better engagement and securement to the described implantable devices. In some embodiments, the contact of the lead is bent. Some embodiments include a coil that engages and secures the lead to the implantable device. Some embodiments include a suture line to aid in securing the lead to the implantable device.
摘要翻译：描述了一种可调式可植入医疗装置和调节装置。在一些实施例中，调节装置包括具有被修改以允许更好地接合和固定到所描述的可植入装置的远端的引线。在一些实施例中，引线的接触是弯曲的。一些实施例包括将引线接合并固定到可植入装置的线圈。一些实施例包括有助于将引线固定到可植入装置的缝合线。

4. 发明申请

WO2008121880A3 ADJUSTABLE ANNULOPLASTY RING AND ACTIVATION SYSTEM 审中-公开
标题翻译：可调整的分批戒指和激活系统
公开(公告)号：WO2008121880A3
公开(公告)日：2008-12-18
申请号：PCT/US2008058757
申请日：2008-03-28
申请人： MICARDIA CORP , SHAOLIAN SAMUEL M , LE LE , FLORES JESUS , TRAN JASON
发明人： SHAOLIAN SAMUEL M , LE LE , FLORES JESUS , TRAN JASON
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61F2/2448 , A61F2/2466 , A61F2250/0001 , A61F2250/0004
摘要： An adjustable annuloplasty device is described. In some embodiments, the device includes a body member having a surface that conforms at least partially to a cardiac valve annulus. The body member comprises a shape-memory member that transforms from a first configuration to a second configuration in response to an applied energy. In some embodiments, the device further includes a first electrode assembly, coupled to the shape-memory member, that transfers energy to the shape-memory member, and a second electrode assembly, coupled to the shape-memory member, that transfers at least a portion of the energy away from the shape-memory member.
摘要翻译：描述了可调整的瓣环成形术装置。在一些实施例中，该装置包括具有至少部分地符合心脏瓣膜瓣环的表面的主体构件。主体构件包括形状记忆构件，所述形状记忆构件响应于所施加的能量而从第一构型转变为第二构型。在一些实施例中，该装置还包括耦合到形状记忆构件的第一电极组件和耦合到形状记忆构件的第二电极组件，第二电极组件耦合到形状记忆构件，第二电极组件传递至少一个部分能量远离形状记忆构件。

5. 发明申请

WO2007111972A2 ACTIVATION DEVICE FOR DYNAMIC RING MANIPULATION 审中-公开
标题翻译：用于动态环控制的激活装置
公开(公告)号：WO2007111972A2
公开(公告)日：2007-10-04
申请号：PCT/US2007/007194
申请日：2007-03-23
申请人： MICARDIA CORPORATION , SHAOLIAN, Samuel , TRAN, Jason , MOADDEB, Shahram , BUCHBINDER, Maurice , ZARBATANY, David
发明人： SHAOLIAN, Samuel , TRAN, Jason , MOADDEB, Shahram , BUCHBINDER, Maurice , ZARBATANY, David
IPC分类号： A61F2/24 , A61B18/18
CPC分类号： A61F2/2445 , A61F2/2466 , A61F2250/0001
摘要： An activation device for applying energy to an implanted annuloplasty ring is described. In some embodiments, the activation device includes an outer elongate member having an outer elongate member distal end and an outer elongate member proximal end, and a lumen therebetween. In some embodiments, the activation device further includes an inner elongate member having a inner elongate member distal end and a inner elongate member proximal end, and a lumen therebetween, wherein the inner elongate member is slidably insertable through the lumen of the outer elongate member. In some embodiments, the activation device further includes at least one adjustable spline having spline proximal and spline distal ends, the spline distal end connected to the inner tubular member distal end and the spline proximal end connected to the outer tubular member distal end, wherein the adjustable spline is configured to flex as the inner tubular member distal end is drawn proximally toward the outer tubular member distal end while the inner elongate member resides in the lumen of the outer elongate member. In some embodiments, the activation device further includes at least one energy-transfer element coupled to the adjustable spline.
摘要翻译：描述了一种用于向植入的瓣膜成形术环施加能量的激活装置。在一些实施例中，激活装置包括具有外部细长构件远端和外部细长构件近端的外部细长构件和其间的内腔。在一些实施例中，激活装置还包括具有内部细长构件远端和内部细长构件近端的内部细长构件和其间的内腔，其中内部细长构件可滑动地插入穿过外部细长构件的内腔。在一些实施例中，激活装置还包括具有花键近端和花键远端的至少一个可调节花键，花键远端连接到内部管状构件远端，花键近端连接到外部管状构件远端，其中，当内部细长构件驻留在外部细长构件的内腔中时，可调节花键构造成随着内部管状构件远端朝向外部管状构件远端被拉近而弯曲。在一些实施例中，激活装置还包括耦合到可调节花键的至少一个能量传递元件。

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