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1. 发明申请

WO2006095324A1 IMAGE PROCESSING SYSTEM AND METHOD FOR REGISTRATION OF TWO-DIMENSIONAL WITH THREE-DIMENSIONAL VOLUME DATA DURING INTERVENTIONAL PROCEDURES 审中-公开
标题翻译：图像处理系统和在传统程序期间用三维体积数据注册二维图像的方法
公开(公告)号：WO2006095324A1
公开(公告)日：2006-09-14
申请号：PCT/IB2006/050733
申请日：2006-03-09
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , TIMMER, Jan , HOMAN, Robert, J., F. , MIELEKAMP, Pieter, M.
发明人： TIMMER, Jan , HOMAN, Robert, J., F. , MIELEKAMP, Pieter, M.
IPC分类号： G06T7/00
CPC分类号： A61B6/4441 , G06T7/35 , G06T2207/30004 , Y10S128/922
摘要： Prior to an intervention, a 3D rotational scan is acquired (at block 10) in respect of a body volume and reconstructed. In addition, three-dimensional image data in respect of the body volume is acquired (at block 12) using another modality, such as computerised tomography (CT) or magnetic resonance (MR), reconstructed, and prepared for visualisation. During the actual intervention, live two-dimensional fluoroscopic images are acquired (at block 14), using the imaging system employed to acquire the 3D rotational scan, and processed for visualisation. The 2D image data is registered (at block 16) to the 3D rotational image data acquired and reconstructed in respect of the body volume of interest, and then a 3D-3D registration process is employed (at block 18) to register the 3D image data acquired in respect of the same body volume using, for example, CT or MR imaging systems to the 3D rotational image data, and a display module (20) is used to align the 2D fluoroscopic image and the 3D MR/CT image as a fused or composite image and display the image.
摘要翻译：在干预之前，相对于身体体积获取3D重复扫描（在方框10）并重构。此外，使用诸如计算机断层摄影（CT）或磁共振（MR）之类的另一种模式，获取关于体积的三维图像数据（方框12），并重建并准备用于可视化。在实际干预过程中，使用用于获取3D旋转扫描的成像系统获取活体二维透视图像（在方框14），并进行可视化处理。将2D图像数据（方框16）登记到相对于感兴趣的身体体积获取和重建的3D旋转图像数据，然后采用3D-3D注册处理（在框18处）以登记3D图像数据使用例如CT或MR成像系统相对于3D旋转图像数据获得相同体积的体积，并且显示模块（20）用于将2D透视图像和3D MR / CT图像对准为融合或合成图像并显示图像。

2. 发明申请

WO2005006257A3 AN IMAGING SYSTEM, AN X-RAY IMAGING APPARATUS, A METHOD AND A COMPUTER PROGRAM ARRANGED FOR REDUCING AN ARTIFACT IN A THREE-DIMENSIONAL RECONSTRUCTED VOLUME 审中-公开
标题翻译：一种用于减少三维重建体积中的伪影的成像系统，X射线成像装置，方法和计算机程序
公开(公告)号：WO2005006257A3
公开(公告)日：2005-10-27
申请号：PCT/IB2004051135
申请日：2004-07-06
申请人： KONINKL PHILIPS ELECTRONICS NV , VAN DE HAAR PETER G , TIMMER JAN
发明人： VAN DE HAAR PETER G , TIMMER JAN
IPC分类号： A61B6/00 , A61B6/02 , G06T5/00 , G06T11/00
CPC分类号： A61B6/4225 , A61B6/583 , A61B6/585 , G06T5/009 , G06T5/50 , G06T2200/04 , G06T2207/10116
摘要： The invention relates to an imaging system (15) comprising artifact reduction means (20) arranged to correct for a ring-shaped artifact in the three-dimensional reconstructed volume. The artifact reduction means (20) comprises a first stage correction means (21) arranged to eliminate the structured noise of the output screen of the image intensifier of an X-ray imaging apparatus (10) using a first corrective image. Preferably, the first corrective image (21a) is pre-calculated and is stored in a suitable memory unit of a computer (not shown). A raw image of the patient is first processed with the first corrective image (21a). The thus obtained gain-corrected image is forwarded to an image deformation correction means (23), where a suitable unwarping function (23a) is being pre-stored. The resulting gain-corrected unwarped images are then made available to the second stage gain correction means (25), where a second corrective image (25a) is applied to the images resulting in a final set of images with a substantially reduced ring-shaped artifact. The final set of images is made available to the image reconstruction means (26) arranged for further processing of the final set of images, the result thereof being visualized on a computer monitor (30) for inspection purposes. The invention further relates to an X-ray imaging apparatus, a method for reducing an artifact in a three-dimensional reconstructed volume and a computer program.
摘要翻译：本发明涉及包括伪影减少装置（20）的成像系统（15），所述伪影减少装置（20）被布置成校正三维重建体积中的环形伪影。伪影减少装置（20）包括第一级校正装置（21），其被布置为使用第一校正图像来消除X射线成像设备（10）的图像增强器的输出屏幕的结构化噪声。优选地，第一校正图像（21a）被预先计算并且被存储在计算机（未示出）的合适的存储单元中。首先用第一矫正图像处理患者的原始图像（21a）。如此获得的经增益校正的图像被传送到图像变形校正装置（23），在该图像变形校正装置中预先存储了合适的非扭曲函数（23a）。然后使得到的经增益校正的未变形图像可用于第二级增益校正装置（25），其中第二校正图像（25a）被应用于图像，导致具有显着减小的环形伪影的最终图像组。最后一组图像可用于图像重构装置（26），该图像重建装置（26）被布置用于进一步处理最终图像集合，其结果在计算机监视器（30）上可视化以用于检查目的。本发明还涉及一种X射线成像装置，一种用于减少三维重建体积中的伪影的方法以及一种计算机程序。

3. 发明申请

WO2009123664A1 NETWORK MANAGEMENT SERVER FOR MANAGING MULTIPLE OPERATING MODES OF A CONFERENCING NETWORK WITH DIFFERENT SETS OF POLICIES 审中-公开
标题翻译：用于管理具有不同策略集团的会议网络的多种操作模式的网络管理服务器
公开(公告)号：WO2009123664A1
公开(公告)日：2009-10-08
申请号：PCT/US2008/082609
申请日：2008-11-06
申请人： FREEPORT TECHNOLOGIES, INC. , TUCKER, Richard W. , MCGREEVY, Gregory J. , SORENSON, Joseph A. , EBBEN, Timothy J. , JOB, Kevin A. , TIMMER, Jan M. , DELHOYO, Sergio Jason , MCGREEVY, John E.
发明人： TUCKER, Richard W. , MCGREEVY, Gregory J. , SORENSON, Joseph A. , EBBEN, Timothy J. , JOB, Kevin A. , TIMMER, Jan M. , DELHOYO, Sergio Jason , MCGREEVY, John E.
IPC分类号： H04L12/28 , H04L12/24 , H04M3/54
CPC分类号： H04N7/152 , H04L12/1827 , H04N7/181
摘要： A method, system, and computer program product are disclosed to manage multiple operating modes in a video conferencing network under which different sets of policies can operate. The system is a network management server, designated herein as the Elastic Gatekeeper, that includes a Conference Management System, which selectively implements one or more different sets of operating policies. The Conference Management System is integrated and linked with a gatekeeper, which is responsible for setting up calls that are using end point alias addresses. The gatekeeper works with the Conference Management System to control access to network resources. Upon receiving a request to access a call, the gatekeeper passes the request to the Conference Management System for its approval. The Conference Management System has access to a robust set of policies, a detailed description of the network resources, and an awareness of the current System Operational Mode upon which to base a decision about the conditions and resources that can be granted to the requested call.
摘要翻译：公开了一种方法，系统和计算机程序产品，用于管理视频会议网络中的多种操作模式，在该视频会议网络中可以操作不同的策略集。该系统是网络管理服务器，在此称为弹性关守，其包括会议管理系统，其选择性地实现一组或多组不同的操作策略。会议管理系统被集成并与一个关守联系，该关守负责设置使用端点别名地址的呼叫。网守与会议管理系统一起控制对网络资源的访问。在接收到访问呼叫的请求时，看门人将请求传递给会议管理系统以供其批准。会议管理系统可以访问一套强大的策略，网络资源的详细描述，以及对当前系统运行模式的认识，根据该系统运行模式，可以对可以授予所请求呼叫的条件和资源做出决定。

4. 发明申请

WO2007113703A3 TARGETING METHOD, TARGETING DEVICE, COMPUTER READABLE MEDIUM AND PROGRAM ELEMENT 审中-公开
标题翻译：目标方法，目标设备，计算机可读介质和程序元素
公开(公告)号：WO2007113703A3
公开(公告)日：2008-07-10
申请号：PCT/IB2007050890
申请日：2007-03-15
申请人： KONINKL PHILIPS ELECTRONICS NV , HOMAN ROBERT JOHANNES FREDERIK , BABIC DRAZENKO , MIELEKAMP PIETER MARIA , TIMMER JAN
发明人： HOMAN ROBERT JOHANNES FREDERIK , BABIC DRAZENKO , MIELEKAMP PIETER MARIA , TIMMER JAN
IPC分类号： A61B17/34
CPC分类号： A61B90/36 , A61B6/4441 , A61B34/10 , A61B2018/2025 , A61B2034/107 , A61B2090/364 , A61B2090/366
摘要： According to an exemplary embodiment a targeting method for targeting a first object from an entry point to a target point in an object (110) under examination is provided, wherein the method comprises selecting a two-dimensional image (301) of the object under examination depicting the entry point (305) and the target point (303) and determining a planned path (304) from the entry point to the target point, wherein the planned path has a first direction. Furthermore, the method comprises recording data representing a fluoroscopic image of the object under examination, wherein the fluoroscopic image is recorded under a second direction so that a normal of the image coincide with the first direction and determining whether the first object is on the determined planned path based on shape and/or position of the projection of the first object in the fluoroscopic image.
摘要翻译：根据示例性实施例，提供了一种用于将第一对象从检查对象（110）中的入口点定位到目标点的目标方法，其中所述方法包括选择被检查对象的二维图像（301）描绘入口点（305）和目标点（303），并从入口点到目标点确定计划路径（304），其中计划路径具有第一方向。此外，该方法包括记录表示所检查对象的透视图像的数据，其中在第二方向上记录荧光镜图像，使得图像的法线与第一方向一致并且确定第一对象是否在确定的计划基于第一对象在透视图像中的投影的形状和/或位置的路径。

5. 发明申请

WO2012031299A3 SYSTEM AND METHOD FOR AUTOMATIC CYCLOTRON PROCEDURES 审中-公开
标题翻译：用于自动循环程序的系统和方法
公开(公告)号：WO2012031299A3
公开(公告)日：2012-08-16
申请号：PCT/US2011050561
申请日：2011-09-06
申请人： VARIAN MEDICAL SYSTEMS PARTICLE THERAPY GMBH , STEPHANI THOMAS , BEHRENS UWE , ROECKEN HEINRICH , BAUMGARTEN CHRISTIAN , TIMMER JAN , HAO JAMES P
发明人： STEPHANI THOMAS , BEHRENS UWE , ROECKEN HEINRICH , BAUMGARTEN CHRISTIAN , TIMMER JAN
IPC分类号： A61N5/10 , H05H13/00
CPC分类号： H05H7/02 , A61N5/10 , A61N5/1077 , A61N2005/1087 , H01J3/14 , H05H13/005 , H05H2007/122 , H05H2277/11
摘要： Systems and methods are provided to perform efficient, automatic adjustment of cyclotron beam currents within a wide range for multiple treatment layers within the same patient and treatment session; and to perform efficient, automatic cyclotron initialization, and calibration. In an embodiment, efficient adjustment is achieved by using beam current attenuation by an electrostatic vertical deflector installed in the inner center of the cyclotron. The beam current may, for example, be adjusted by the high voltage applied to the electrostatic vertical deflector, in front of each treatment the attenuation curve of the vertical deflector is recorded. Based on this attenuation curve, the vertical deflector voltage for the needed beam current of each irradiation layer is interpolated. In another embodiment, a process is provided that allows the automation of the initialization of a cyclotron after overnight or maintenance imposed shutdown. In one embodiment, five independent cyclotron system states are defined and the transition between one state to another may be automated, e.g., by the control system of the cyclotron.
摘要翻译：提供系统和方法以在相同的患者和治疗期内对多个治疗层在宽范围内执行高效的自动调节回旋束电流; 并执行高效的自动回旋加速器初始化和校准。在一个实施例中，通过使用安装在回旋加速器内部中心的静电垂直偏转器的束电流衰减来实现有效调节。束流例如可以通过施加到静电垂直偏转器的高电压来调节，在每次处理之前记录垂直偏转器的衰减曲线。基于该衰减曲线，内插每个照射层所需射束电流的垂直偏转器电压。在另一个实施例中，提供了一种过程，该过程允许在隔夜或维护强制关机后自动化回旋加速器的初始化。在一个实施例中，定义了五个独立的回旋加速器系统状态，并且一个状态到另一个状态之间的转换可以例如通过回旋加速器的控制系统自动化。

6. 发明申请

WO2012031299A2 SYSTEM AND METHOD FOR AUTOMATIC CYCLOTRON PROCEDURES 审中-公开
标题翻译：自动循环程序的系统和方法
公开(公告)号：WO2012031299A2
公开(公告)日：2012-03-08
申请号：PCT/US2011/050561
申请日：2011-09-06
申请人： VARIAN MEDICAL SYSTEMS PARTICLE THERAPY GMBH , STEPHANI, Thomas , BEHRENS, Uwe , ROECKEN, Heinrich , BAUMGARTEN, Christian , TIMMER, Jan , HAO, James, P.
发明人： STEPHANI, Thomas , BEHRENS, Uwe , ROECKEN, Heinrich , BAUMGARTEN, Christian , TIMMER, Jan
IPC分类号： A61N5/10 , H05H13/00
CPC分类号： H05H7/02 , A61N5/10 , A61N5/1077 , A61N2005/1087 , H01J3/14 , H05H13/005 , H05H2007/122 , H05H2277/11
摘要： Systems and methods are provided to perform efficient, automatic adjustment of cyclotron beam currents within a wide range for multiple treatment layers within the same patient and treatment session; and to perform efficient, automatic cyclotron initialization, and calibration. In an embodiment, efficient adjustment is achieved by using beam current attenuation by an electrostatic vertical deflector installed in the inner center of the cyclotron. The beam current may, for example, be adjusted by the high voltage applied to the electrostatic vertical deflector, in front of each treatment the attenuation curve of the vertical deflector is recorded. Based on this attenuation curve, the vertical deflector voltage for the needed beam current of each irradiation layer is interpolated. In another embodiment, a process is provided that allows the automation of the initialization of a cyclotron after overnight or maintenance imposed shutdown. In one embodiment, five independent cyclotron system states are defined and the transition between one state to another may be automated, e.g., by the control system of the cyclotron.
摘要翻译：提供系统和方法以在相同的患者和治疗期间内的多个治疗层的范围内对回旋加速器束电流进行有效的自动调节; 并执行有效的自动回旋加速器初始化和校准。在一个实施例中，通过使用安装在回旋加速器的内部中心的静电垂直偏转器来使用束流衰减来实现有效的调节。例如，通过施加到静电垂直偏转器的高电压来调节束电流，在每个处理前面记录垂直偏转器的衰减曲线。基于该衰减曲线，对每个照射层所需的束电流的垂直偏转器电压进行插值。在另一个实施例中，提供了一种过程，其允许在过夜或维护强制停机之后对回旋加速器的初始化进行自动化。在一个实施例中，定义了五个独立的回旋加速器系统状态，并且一个状态与另一个状态之间的转换可以例如由回旋加速器的控制系统自动化。

7. 发明申请

WO2008083721A1 BESTRAHLUNGSVORRICHTUNG 审中-公开
标题翻译：辐射装置
公开(公告)号：WO2008083721A1
公开(公告)日：2008-07-17
申请号：PCT/EP2007/003116
申请日：2007-04-05
申请人： ACCEL INSTRUMENTS GMBH , TIMMER, Jan, Hein , GÖBEL, Holger , SCHMIDT, Stefan , HEESE, Jürgen , SCHILLO, Michael
发明人： TIMMER, Jan, Hein , GÖBEL, Holger , SCHMIDT, Stefan , HEESE, Jürgen , SCHILLO, Michael
IPC分类号： A61N5/10 , G21K5/10
CPC分类号： A61N5/10 , A61N5/1081 , A61N2005/1087
摘要： Die vorliegende Erfindung betrifft eine Bestrahlungsvorrichtung zur Bestrahlung eines Bestrahlungsobjekts mit schweren geladenen Teilchen an einem Bestrahlungsplatz, mit einem Teilchenbeschleuniger zur Bereitstellung eines Teilchenstrahls und einer Schwenkvorrichtung zum Schwenken des auf das Bestrahlungsobjekt treffenden Teilchenstrahls, wobei die Schwenkvorrichtung einen um eine Achse schwenkbaren Träger umfaßt. Erfindungsgemäß zeichnet sich die Bestrahlungsvorrichtung dadurch aus, daß der Teilchenbeschleuniger auf dem schwenkbaren Träger montiert ist.
摘要翻译：本发明涉及一种照射装置，用于在辐照台照射重带电粒子的照射对象，具有用于提供一个粒子束的粒子加速器和用于枢转枢转装置，所述撞击照射对象粒子束，其中所述枢转装置包括围绕轴线的载体的枢转。根据本发明，所述照射装置的特征在于，所述粒子加速器安装在可枢转的载体上。

8. 发明申请

WO2008012710A1 X-RAY DETECTOR GAIN CALIBRATION DEPENDING ON THE FRACTION OF SCATTERED RADIATION 审中-公开
标题翻译：依赖于散射辐射的X射线探测器增益校准
公开(公告)号：WO2008012710A1
公开(公告)日：2008-01-31
申请号：PCT/IB2007/052723
申请日：2007-07-10
申请人： KONINKLIJKE PHILIPS ELECTRONICS N. V. , TIMMER, Jan , VAN DE HAAR, Peter George
发明人： TIMMER, Jan , VAN DE HAAR, Peter George
IPC分类号： A61B6/03
CPC分类号： G01D18/00 , A61B6/032 , A61B6/4085 , A61B6/4291 , A61B6/5258 , A61B6/5282 , A61B6/583 , A61B6/585
摘要： It is described a gain calibration for a two-dimensional X-ray detector (315), in which the gain coefficients for scattered radiation (307b) and direct radiation (307a) are measured or estimated separately. A weighed average may be applied on the appropriate scatter fraction. The scatter fraction depending gain calibration method produces less ring artifacts in X-ray images as compared to known gain calibration methods, which do not take into account the fraction of scattered radiation reaching the X-ray detector (315).
摘要翻译：描述了用于二维X射线检测器（315）的增益校准，其中散射辐射（307b）和直接辐射（307a）的增益系数被分别测量或估计。加权平均值可以应用于适当的分散分数。与已知的增益校准方法相比，散射分数依赖增益校准方法在X射线图像中产生较少的环形伪影，其不考虑到到达X射线检测器的散射辐射的分数（315）。

9. 发明申请

WO2007148263A1 METHOD AND SYSTEM FOR ERROR COMPENSATION 审中-公开
标题翻译：错误补偿的方法和系统
公开(公告)号：WO2007148263A1
公开(公告)日：2007-12-27
申请号：PCT/IB2007/052243
申请日：2007-06-13
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , BERTRAM, Matthias , WIEGERT, Jens , TIMMER, Jan , NOORDHOEK, Nicolaas Jan
发明人： BERTRAM, Matthias , WIEGERT, Jens , TIMMER, Jan , NOORDHOEK, Nicolaas Jan
IPC分类号： G06T5/00 , G06T11/00
CPC分类号： G06T11/005 , G06T5/003 , G06T2207/10081 , G06T2207/30004
摘要： A method for generating a set of kernels for convolution error compensation of a projection image of a physical object recorded by an imaging system comprises calculating the set of kernels in such a way that for each pixel of the projection image an asymmetric scatter distribution for error compensation is calculated representing a X-ray scatter originating along a ray from an X-ray source to the pixel.
摘要翻译：用于生成用于由成像系统记录的物理物体的投影图像的卷积误差补偿的一组内核的方法包括以对投影图像的每个像素进行误差补偿的不对称散布分布的方式来计算该组内核表示沿着从X射线源到像素的射线发生的X射线散射。

10. 发明申请

WO2005008586A3 METAL ARTIFACT CORRECTION IN COMPUTED TOMOGRAPHY 审中-公开
公开(公告)号：WO2005008586A3
公开(公告)日：2005-01-27
申请号：PCT/IB2004/002325
申请日：2004-07-16
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , U.S. PHILIPS CORPORATION , TIMMER, Jan
发明人： TIMMER, Jan
IPC分类号： A61B6/03
摘要： An artifact correcting image reconstruction apparatus includes a reconstruction processor (70) that reconstructs acquired projection data (60) into an uncorrected reconstructed image (74). A classifying processor (78) classifies pixels of the uncorrected reconstructed image (74) at least into high, medium, and low density pixel classes. A pixel replacement processor (88) replaces pixels of the uncorrected reconstructed image (74) that are of the high density and low density classes with pixel values of the low density pixel class to generate a synthetic image (90). A forward projecting processor (94) forward projects the synthetic image (90) to generate synthetic projection data (96). A projection replacement processor (100, 110) replaces acquired projection data (60) contributing to the pixels of the high density class with corresponding synthetic projection data (96) to generate corrected projection data (112). The reconstruction processor (70) reconstructs the corrected projection data (112) into a corrected reconstructed image (120).

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