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1. 发明申请

WO2012031299A2 SYSTEM AND METHOD FOR AUTOMATIC CYCLOTRON PROCEDURES 审中-公开
标题翻译：自动循环程序的系统和方法
公开(公告)号：WO2012031299A2
公开(公告)日：2012-03-08
申请号：PCT/US2011/050561
申请日：2011-09-06
申请人： VARIAN MEDICAL SYSTEMS PARTICLE THERAPY GMBH , STEPHANI, Thomas , BEHRENS, Uwe , ROECKEN, Heinrich , BAUMGARTEN, Christian , TIMMER, Jan , HAO, James, P.
发明人： STEPHANI, Thomas , BEHRENS, Uwe , ROECKEN, Heinrich , BAUMGARTEN, Christian , TIMMER, Jan
IPC分类号： A61N5/10 , H05H13/00
CPC分类号： H05H7/02 , A61N5/10 , A61N5/1077 , A61N2005/1087 , H01J3/14 , H05H13/005 , H05H2007/122 , H05H2277/11
摘要： Systems and methods are provided to perform efficient, automatic adjustment of cyclotron beam currents within a wide range for multiple treatment layers within the same patient and treatment session; and to perform efficient, automatic cyclotron initialization, and calibration. In an embodiment, efficient adjustment is achieved by using beam current attenuation by an electrostatic vertical deflector installed in the inner center of the cyclotron. The beam current may, for example, be adjusted by the high voltage applied to the electrostatic vertical deflector, in front of each treatment the attenuation curve of the vertical deflector is recorded. Based on this attenuation curve, the vertical deflector voltage for the needed beam current of each irradiation layer is interpolated. In another embodiment, a process is provided that allows the automation of the initialization of a cyclotron after overnight or maintenance imposed shutdown. In one embodiment, five independent cyclotron system states are defined and the transition between one state to another may be automated, e.g., by the control system of the cyclotron.
摘要翻译：提供系统和方法以在相同的患者和治疗期间内的多个治疗层的范围内对回旋加速器束电流进行有效的自动调节; 并执行有效的自动回旋加速器初始化和校准。在一个实施例中，通过使用安装在回旋加速器的内部中心的静电垂直偏转器来使用束流衰减来实现有效的调节。例如，通过施加到静电垂直偏转器的高电压来调节束电流，在每个处理前面记录垂直偏转器的衰减曲线。基于该衰减曲线，对每个照射层所需的束电流的垂直偏转器电压进行插值。在另一个实施例中，提供了一种过程，其允许在过夜或维护强制停机之后对回旋加速器的初始化进行自动化。在一个实施例中，定义了五个独立的回旋加速器系统状态，并且一个状态与另一个状态之间的转换可以例如由回旋加速器的控制系统自动化。

2. 发明申请

WO2014108334A1 BEAM CURRENT VARIATION SYSTEM FOR A CYCLOTRON 审中-公开
标题翻译：用于循环的光束电流变化系统
公开(公告)号：WO2014108334A1
公开(公告)日：2014-07-17
申请号：PCT/EP2014/000027
申请日：2014-01-09
申请人： VARIAN MEDICAL SYSTEMS PARTICLE THERAPY GMBH
发明人： STEPHANI, Thomas , ROCKEN, Heinrich
IPC分类号： H05H7/00 , H05H13/00
CPC分类号： H05H7/08 , H05H7/00 , H05H13/005 , H05H2007/085
摘要： Beam current variation system for a cyclotron, arranged in the inner centre of the cyclotron, downstream from the ion source generating the charged particle beam, the system comprising a deflector system powered by a voltage and a collimator. The beam is dumped in the collimator, if the deflector system (10; 20, 21) is not powered, and the beam is switched on by powering the deflector system with a voltage.
摘要翻译：用于回旋加速器的光束电流变化系统，布置在回旋加速器的内部中心，离子源的下游产生带电粒子束，该系统包括由电压和准直器供电的偏转器系统。如果偏转器系统（10; 20,21）没有被供电，则光束被倾倒在准直器中，并且通过用电压对偏转器系统供电来使光束被接通。

3. 发明公开

EP2611501A2 SYSTEM AND METHOD FOR AUTOMATIC CYCLOTRON PROCEDURES 有权转让
标题翻译：系统和方法自动ZYKLOTRONVERFAHREN
公开(公告)号：EP2611501A2
公开(公告)日：2013-07-10
申请号：EP11822779.2
申请日：2011-09-06
申请人： Varian Medical Systems Particle Therapy GmbH
发明人： STEPHANI, Thomas , BEHRENS, Uwe , ROECKEN, Heinrich , BAUMGARTEN, Christian , TIMMER, Jan
IPC分类号： A61N5/10 , H05H13/00
CPC分类号： H05H7/02 , A61N5/10 , A61N5/1077 , A61N2005/1087 , H01J3/14 , H05H13/005 , H05H2007/122 , H05H2277/11
摘要： Systems and methods are provided to perform efficient, automatic adjustment of cyclotron beam currents within a wide range for multiple treatment layers within the same patient and treatment session; and to perform efficient, automatic cyclotron initialization, and calibration. In an embodiment, efficient adjustment is achieved by using beam current attenuation by an electrostatic vertical deflector installed in the inner center of the cyclotron. The beam current may, for example, be adjusted by the high voltage applied to the electrostatic vertical deflector, in front of each treatment the attenuation curve of the vertical deflector is recorded. Based on this attenuation curve, the vertical deflector voltage for the needed beam current of each irradiation layer is interpolated. In another embodiment, a process is provided that allows the automation of the initialization of a cyclotron after overnight or maintenance imposed shutdown. In one embodiment, five independent cyclotron system states are defined and the transition between one state to another may be automated, e.g., by the control system of the cyclotron.

4. 发明授权

EP2611501B1 SYSTEM AND METHOD FOR AUTOMATIC CYCLOTRON PROCEDURES 有权转让
公开(公告)号：EP2611501B1
公开(公告)日：2020-10-28
申请号：EP11822779.2
申请日：2011-09-06
申请人： Varian Medical Systems Particle Therapy GmbH
发明人： STEPHANI, Thomas , BEHRENS, Uwe , ROECKEN, Heinrich , BAUMGARTEN, Christian , TIMMER, Jan
IPC分类号： A61N5/10 , H05H13/00 , H05H7/12 , H05H7/02 , H01J3/14

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