会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 6. 发明授权
    • High production method of prenyl alcohol using saccharomyces cells
    • 使用酵母细胞制备异戊醇的高生产方法
    • US06974685B2
    • 2005-12-13
    • US10022434
    • 2001-12-20
    • Masayoshi MuramatsuShusei ObataSakayu Shimizu
    • Masayoshi MuramatsuShusei ObataSakayu Shimizu
    • C12N1/38C12P7/04C12R1/645C12P7/02
    • C12N1/38C12P7/04
    • The present invention provides a high production method of prenyl alcohol, which comprises culturing prenyl alcohol-producing cells in a medium with an increased sugar content in the presence of at least one member selected from the group consisting of a surfactant, a fat or oil, and a terpene to produce and accumulate prenyl alcohol in the cells; allowing the accumulated prenyl alcohol to be secreted from the cells; and then collecting prenyl alcohol. The present invention enables prenyl alcohol to be highly produced in and effectively secreted from prenyl alcohol-producing cells by culturing the cells in a medium with an increased sugar content in the presence of at least one member selected from the group consisting of a surfactant, a fat or oil, and a terpene.
    • 本发明提供了高产的异戊醇的制备方法,其包括在选自表面活性剂,脂肪或油中的至少一种的存在下,在具有增加的糖含量的培养基中培养异戊醇产生细胞, 和萜烯在细胞中产生和积累异戊醇; 允许从细胞中分泌积累的异戊醇; 然后收集异戊醇。 本发明通过在选自表面活性剂,表面活性剂,表面活性剂的至少一种的存在下,在具有增加的糖含量的介质中培养细胞,使异戊烯醇高产生并由异戊烯醇产生细胞有效分泌 脂肪或油,和萜烯。
    • 7. 发明授权
    • Method for production of geranylgeraniol and analogous compounds thereof by microorganisms
    • 通过微生物生产香叶基香叶醇及其类似物的方法
    • US06972191B2
    • 2005-12-06
    • US10022695
    • 2001-12-20
    • Masayoshi MuramatsuShusei ObataSakayu Shimizu
    • Masayoshi MuramatsuShusei ObataSakayu Shimizu
    • C07C33/02C12P7/04C12R1/85C12P7/02
    • C12P7/04
    • The present invention provides a method for producing geranylgeraniol and analogous compounds thereof, which comprises culturing yeast cells (ascomycetes and deuteromycetes), bacterial cells, actinomycete cells or filamentous fungus cells, all of which are capable of producing geranylgeraniol and analogous compounds thereof, in a medium to produce and accumulate geranylgeraniol and analogous compounds thereof in the cells and/or in the extracellular environment; and then collecting these compounds. The present invention enables inexpensive mass production of geranylgeraniol and analogous compounds thereof by using microorganisms capable of producing geranylgeraniol, farnesol and/or nerolidol useful as biosynthetic intermediates of terpenes, carotenoids and/or steroids.
    • 本发明提供了一种生产香叶基香叶醇及其类似化合物的方法,其包括培养酵母细胞(子囊菌和氘核菌素),细菌细胞,放线菌细胞或丝状真菌细胞,所有这些能够产生香叶基香叶醇及其类似物 培养基以在细胞和/或细胞外环境中产生和积累香叶基香叶醇及其类似物; 然后收集这些化合物。 本发明可以通过使用能够产生香叶基香叶醇,法呢醇和/或橙花叔醇作为萜烯,类胡萝卜素和/或类固醇的生物合成中间体的微生物,从而廉价地批量生产香叶基香叶醇及其类似物。
    • 10. 发明授权
    • Method for production of polylactate using recombinant microorganism
    • 使用重组微生物生产聚乳酸的方法
    • US08748137B2
    • 2014-06-10
    • US13126157
    • 2009-10-27
    • Shusei ObataHiromi KambeMasakazu ItoTakashi ShimamuraKatsunori KohdaSeiichi Taguchi
    • Shusei ObataHiromi KambeMasakazu ItoTakashi ShimamuraKatsunori KohdaSeiichi Taguchi
    • C12P7/62C12N9/00C12N9/10C12N1/20C12N15/00C07H21/04
    • C12P7/62C12N9/1029
    • It is an object of the present invention to provide a method for efficiently producing a polylactate via microbial fermentation with the use of a sugar as a starting material.The method is a method for producing a polylactate, which comprises the steps of: (1) culturing a recombinant microorganism having a protein capable of catalyzing a reaction of transferring CoA to propionic acid and/or lactate and a protein capable of catalyzing a reaction of polyhydroxyalkanoate synthesis consisting of the following amino acid sequence (a) or (b) in a medium containing a carbon source: (a) an amino acid sequence derived from the amino acid sequence shown in SEQ ID NO: 2 by substitution of at least one of the amino acids at positions 130, 325, 477, and 481 with different amino acid(s); or (b) an amino acid sequence derived from the protein specified in (a) by additional deletion or substitution of one or several amino acid(s) other than the amino acids at positions 130, 325, 477, and 481 or by insertion of one or several amino acid residue(s); and (2) collecting the polylactate from the culture product obtained in step (1).
    • 本发明的目的是提供一种利用糖作为起始原料通过微生物发酵有效生产聚乳酸的方法。 该方法是制备聚乳酸的方法,其包括以下步骤:(1)培养具有能够催化将CoA转移到丙酸和/或乳酸的反应的蛋白质的蛋白质和能够催化反应的蛋白质的重组微生物 在含有碳源的培养基中由以下氨基酸序列(a)或(b)组成的聚羟基链烷酸酯合成物:(a)通过至少一个取代至少一个氨基酸序列的氨基酸序列,所述氨基酸序列来自SEQ ID NO:2所示的氨基酸序列 的具有不同氨基酸的位置130,325,477和481处的氨基酸; 或(b)衍生自(a)中规定的蛋白质的氨基酸序列,通过除了位置130,325,477和481之外的氨基酸以外的一个或几个氨基酸的另外缺失或取代,或通过插入 一个或几个氨基酸残基; 和(2)从步骤(1)获得的培养产物中收集聚乳酸。