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1. 发明授权

US08790156B2 Tooth-profile management system for shaving-cutter grinding machine 有权
标题翻译：剃须刀磨床牙齿管理系统
公开(公告)号：US08790156B2
公开(公告)日：2014-07-29
申请号：US13502752
申请日：2010-10-06
申请人： Yoshikoto Yanase , Ryuzo Hayashi
发明人： Yoshikoto Yanase , Ryuzo Hayashi
IPC分类号： B24B49/18
CPC分类号： B23F19/06 , B23F21/28 , B24B49/02 , B24B53/085
摘要： A personal computer has correction coefficients (α) for tooth-profile error correction and correction coefficients (β) for meshing position correction which are set for each number of times a shaving cutter is sharpened, and for each cutter feature of the shaving cutter. Target tooth-profile data (Do), tooth-profile error data (ΔD) which is the difference between the target tooth-profile data (Do) and measured tooth-profile data (Dm), and the correction coefficient (α) and the correction coefficient (β) captured in correspondence with the number of times sharpening is performed, and the cutter features are applied to an equation Dcc=Do+α·ΔD+β to find aimed tooth-profile data (Dcc). Shaving-cutter tooth-profile data (ds) is found from the aimed tooth-profile data (Dcc). Thus, the shaving cutter can be sharpened appropriately even when the outer diameter and tooth thickness of the shaving cutter are reduced by sharpening the shaving cutter.
摘要翻译：个人计算机具有用于齿廓修正的校正系数（α）和针对剃须刀被削尖的每个次数设定的啮合位置校正的校正系数（＆bgr），以及剃须刀的每个切割器特征。目标齿廓数据（Do），作为目标齿廓数据（Do）与测量齿廓数据（Dm）之间的差异的齿廓误差数据（＆Dgr; D）和校正系数（α）并且与执行锐化次数相对应地捕获的校正系数（＆bgr），并且切割器特征被应用于等式Dcc = Do +α·＆Dgr; D +＆bgr; 找到目标牙齿轮廓数据（Dcc）。从目标牙齿轮廓数据（Dcc）中可以看到剃刀齿廓数据（ds）。因此，即使通过磨削剃须刀来减少剃须刀的外径和齿厚度，也可以适当地削尖剃须刀。

2. 发明授权

US5320939A Measuring apparatus of two components using enzyme electrodes and the measuring method thereof 失效
标题翻译：使用酶电极的两个组分的测量装置及其测量方法
公开(公告)号：US5320939A
公开(公告)日：1994-06-14
申请号：US953294
申请日：1992-09-30
申请人： Yoshio Hashizume , Ryuzo Hayashi , Akio Kariyone
发明人： Yoshio Hashizume , Ryuzo Hayashi , Akio Kariyone
IPC分类号： G01N27/26 , C12Q1/00 , G01N27/27 , G01N27/403 , G01N27/416
CPC分类号： C12Q1/001 , Y10S435/817
摘要： In a two-substrate measuring apparatus employing a first enzyme electrode for responding only to a first substrate to be measured and a second enzyme electrode for responding to both first and second substrates to be measured, in which the same enzymatic reactions are used for forming detectable substances and the substances to be finally detected by the electrodes are identical, when calculating the calibration curve for the second substrate to be measured, the output portion due to traces of the first substrate contained in the second substrate to be measured is removed, so that the second substrate is measured at a high sensitivity and high accuracy.
摘要翻译：在使用第一酶电极仅响应待测量的第一基底的第二酶电极和用于响应于待测量的第一和第二基底的第二酶电极的双基底测量装置中，其中使用相同的酶反应形成可检测的物质和由电极最终检测到的物质在计算待测量的第二基板的校准曲线时是相同的，除去由于包含在待测量的第二基板中的第一基板的痕迹引起的输出部分，从而以高灵敏度和高精度测量第二基板。

3. 发明授权

US4971901A Process for preparing enzyme electrodes 失效
标题翻译：制备酶电极的方法
公开(公告)号：US4971901A
公开(公告)日：1990-11-20
申请号：US146202
申请日：1988-01-20
申请人： Ryuzo Hayashi , Akio Kariyone
发明人： Ryuzo Hayashi , Akio Kariyone
IPC分类号： G01N27/327 , C12Q1/00
CPC分类号： C12Q1/005 , Y10S435/817
摘要： An enzyme electrode is prepared by a process wherein an albumin solution containing 0.05 to 0.5% by weight of a multifunctional aldehyde is applied onto the surface of an electroconductive substrate while maintaining the atmospheric temperature at 0.degree. to 20.degree. C. to thereby form a crosslinked albumin layer on the surface of the electroconductive substrate. Thereafter a solution containing 0.5% by weight or less of a multifunctional aldehyde and a predetermined amount of an oxidase capable of producing hydrogen peroxide (H.sub.2 O.sub.2) is applied on the surface of the previously formed crosslinked albumin layer to form a H.sub.2 O.sub.2 productive oxidase containing layer.

4. 发明申请

US20080223733A1 Analysis Apparatus and Analysis Method for Glycosylated Hemoglobin 有权
标题翻译：糖基化血红蛋白的分析仪器及分析方法
公开(公告)号：US20080223733A1
公开(公告)日：2008-09-18
申请号：US11913367
申请日：2006-05-02
申请人： Yoko Nanjo , Ryuzo Hayashi
发明人： Yoko Nanjo , Ryuzo Hayashi
IPC分类号： C12M1/00 , C12Q1/00
CPC分类号： C12Q1/005 , G01N33/723
摘要： Disclosed is a method for calculating a ratio of glycosylated hemoglobin with high accuracy by electrochemically detecting the concentration of fructosyl valine or fructosyl valyl-histidine in a sample. Also disclosed is an apparatus for assaying glucose and glycosylated hemoglobin simultaneously. Further disclosed are a method and an apparatus for removing hydrogen peroxide in a sample.
摘要翻译：公开了通过电化学检测样品中果糖基缬氨酸或果糖基缬氨酰基 - 组氨酸的浓度来计算糖基化血红蛋白的比例高的方法。还公开了同时测定葡萄糖和糖基化血红蛋白的装置。还公开了一种用于去除样品中的过氧化氢的方法和装置。

5. 发明授权

US5992221A Concentration measuring apparatus 失效
标题翻译：浓度测定仪
公开(公告)号：US5992221A
公开(公告)日：1999-11-30
申请号：US703700
申请日：1996-08-27
申请人： Akio Kariyone , Yoshio Hashizume , Ryuzo Hayashi
发明人： Akio Kariyone , Yoshio Hashizume , Ryuzo Hayashi
IPC分类号： G01N1/00 , G01N1/38 , G01N1/16 , G01N15/06
CPC分类号： G01N1/38 , G01N35/1095
摘要： Pipes provided with each switching valve in intermediate portions thereof for feeding sample solutions to a separation mechanism are joined by a multi-way joint, to reach the separation mechanism through a pump. When all valves are closed while driving the pump and thereafter one valve is opened, all bubbles etc. downstream the opened valve are swept and eliminated due to abrupt flow of a liquid since a portion downstream the valve has been decompressed. In switching of a sample in sample measurement, a valve of a pipe for a completely measured sample is left open while a valve of a pipe for a next sample is opened, and then the valve of the pipe for the previously completely measured sample is closed after a while. Thus, pressure fluctuation following sample switching is avoided.
摘要翻译：在其中间部分设置有用于将样品溶液供给到分离机构的每个切换阀的管道通过多向接头连接，以通过泵到达分离机构。当所有阀在驱动泵时关闭，此后一个阀打开，所以打开的阀下游的所有气泡等均由于液体的急剧流动被扫除并消除，因为阀下游的部分已被减压。在样品测量中切换样品时，用于完全测量样品的管道的阀门打开，而用于下一个样品的管道的阀门打开，然后用于先前完全测量的样品的管道阀门关闭过了一会儿。因此，避免了样品切换后的压力波动。

6. 发明授权

US5510244A Apparatus and method for assaying optical isomers 失效
标题翻译：用于测定光学异构体的装置和方法
公开(公告)号：US5510244A
公开(公告)日：1996-04-23
申请号：US67960
申请日：1993-05-27
申请人： Yukie Inoue , Ryuzo Hayashi , Naoka Matsuya
发明人： Yukie Inoue , Ryuzo Hayashi , Naoka Matsuya
IPC分类号： C12N11/14 , C12Q1/00 , C12Q1/26 , C12Q1/32 , G01N21/00
CPC分类号： C12Q1/005 , C12N11/14 , C12Q1/26 , C12Q1/32 , Y10S435/81 , Y10S435/973 , Y10S435/975
摘要： A method, apparatus and kit for assaying the L- and D-optical isomers and optionally the oxidation product derived from a L- (or D-) optical isomer.
摘要翻译：用于测定L-和D-光学异构体的方法，装置和试剂盒，以及任选的衍生自L-（或D-）旋光异构体的氧化产物。

7. 发明授权

US5225321A Measuring apparatus using enzyme electrodes and the method thereof 失效
标题翻译：使用酶电极的测量装置及其方法
公开(公告)号：US5225321A
公开(公告)日：1993-07-06
申请号：US727341
申请日：1991-07-08
申请人： Ryuzo Hayashi , Akio Kariyone , Yoshio Hashizume
发明人： Ryuzo Hayashi , Akio Kariyone , Yoshio Hashizume
IPC分类号： C12Q1/00 , G01N27/403
CPC分类号： C12Q1/001 , C12Q1/005 , C12Q1/006
摘要： In the case of measuring concentration of, for example, glucose as a first substance to be measured, and that of sucrose as a second substance to be measured, using a measuring apparatus, the apparatus is provided with a first enzyme electrode, a dilution pipeline situated at the downstream of the electrode and for diluting the substances, and a second enzyme electrode situated at the downstream of the dilution pipeline. A sample, which contains the first and second substances, is poured intermittently into a constant flow of a buffer solution. The first enzyme electrode detects the first substance. The second enzyme electrode, which comprises an immobilized enzyme catalizing the conversion of the second substance in to the first substance, detects the first substance, which is originally contained in the sample as well as is formed on the second enzyme electrode. The concentration of the second substance in the sample can be determined by calculating about the outputs of the first and second enzyme electrodes.
摘要翻译：在测量作为第一待测物质的葡萄糖的浓度和作为第二待测物质的蔗糖的浓度的情况下，使用测量装置，设置有第一酶电极，稀释管线位于电极的下游并用于稀释物质，以及位于稀释管道下游的第二酶电极。将含有第一和第二物质的样品间歇地倒入缓冲溶液的恒定流中。第一酶电极检测第一物质。第二酶电极，其包含催化第二物质向第一物质转化的固定化酶，检测原样包含在样品中的第一物质，并形成在第二酶电极上。可以通过计算第一和第二酶电极的输出来确定样品中第二物质的浓度。

8. 发明授权

US5037527A Reference electrode and a measuring apparatus using the same 失效
标题翻译：参考电极和使用其的测量装置
公开(公告)号：US5037527A
公开(公告)日：1991-08-06
申请号：US235970
申请日：1988-08-24
申请人： Ryuzo Hayashi , Kariyone Akio , Yoshio Hashizume
发明人： Ryuzo Hayashi , Kariyone Akio , Yoshio Hashizume
IPC分类号： G01N27/30
CPC分类号： G01N27/301 , G03C2001/0471
摘要： A reference electrode for use in a flow type measuring apparatus incorporating an immobilized enzyme working electrode, wherein a hydrophilic gel layer is provided on a silver chloride containing layer in order to prevent flow-out of silver ions that are likely to adversely affect enzyme activity, so that the silver chloride containing layer goes into contact through the hydrophilic gel layer with an electrolytic solution containing a substance to be measured.

9. 发明授权

US5034330A Preparation of a selectively permeable membrane for an enzyme electrode 失效
标题翻译：制备用于酶电极的选择性渗透膜
公开(公告)号：US5034330A
公开(公告)日：1991-07-23
申请号：US301032
申请日：1989-01-24
申请人： Tsunefumi Yamori , Eiji Yuasa , Ryuzo Hayashi
发明人： Tsunefumi Yamori , Eiji Yuasa , Ryuzo Hayashi
IPC分类号： G01N27/327 , C12N11/08 , C12Q1/00 , G01N27/30 , G01N27/416
CPC分类号： C12Q1/002 , Y10S435/817
摘要： A selectively permeable membrane for an enzyme electrode is prepared by forming a mixture of an emulsion of resin containing at least one prepolymer or monomer having ethylenic unsaturation, and a water-soluble polymer material, and subjecting the mixture to irradiation with ionizing or ultraviolet irradiation. The membrane is permeable to substances produced by an enzyme reaction while preventing the permeation of higher molecular weight materials. An immobilized enzyme membrane is formed on an outer surface of the permeable membrane, and the resultant membrane is mounted on an electrically conductive base to form an enzyme electrode. In another embodiment, the selectively permeable membrane is formed on the electrically conductive base, and then the immobilized enzyme membrane is formed. The selectively permeable membrane is situated between the immobilized enzyme membrane, which is in contact with a sample solution, and the electrically conductive base.

10. 发明授权

US08128802B2 Analysis apparatus and analysis method for glycosylated hemoglobin 有权
标题翻译：糖化血红蛋白的分析仪器及分析方法
公开(公告)号：US08128802B2
公开(公告)日：2012-03-06
申请号：US11913367
申请日：2006-05-02
申请人： Yoko Nanjo , Ryuzo Hayashi
发明人： Yoko Nanjo , Ryuzo Hayashi
IPC分类号： G01N27/327
CPC分类号： C12Q1/005 , G01N33/723
摘要： Disclosed is a method for calculating a ratio of glycosylated hemoglobin with high accuracy by electrochemically detecting the concentration of fructosyl valine or fructosyl valyl-histidine in a sample. Also disclosed is an apparatus for assaying glucose and glycosylated hemoglobin simultaneously. Further disclosed are a method and an apparatus for removing hydrogen peroxide in a sample.
摘要翻译：公开了通过电化学检测样品中果糖基缬氨酸或果糖基缬氨酰基 - 组氨酸的浓度来计算糖基化血红蛋白的比例高的方法。还公开了同时测定葡萄糖和糖基化血红蛋白的装置。还公开了一种用于去除样品中的过氧化氢的方法和装置。

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