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1. 发明专利

FR2896491A1 DEVIDOIR SEMIAUTOMATIQUE DE FEUILLES, EN PARTICULIER DE PAPIER A CIGARETTES 未知
公开(公告)号：FR2896491A1
公开(公告)日：2007-07-27
申请号：FR0650233
申请日：2006-01-23
申请人： CASTANHEIRA MARQUES GIL RUI MA
发明人： CASTANHEIRA MARQUES GIL RUI M
IPC分类号： B65H1/04 , A24F17/00 , B65H3/20
摘要： La mise en place de moyens adhésifs (38, 38') sur un étui (30) de feuilles de papier à cigarettes permet une extraction semi-automatique feuille à feuille, et une solidarisation temporaire de la feuille extraite avec le rabat de l'étui (30). Outre la simplicité d'utilisation et la facilité de prélèvement en cas de vent ou de handicap, le système selon l'invention offre une hygiène accrue.Un tel système peut par ailleurs s'appliquer à d'autres étuis de feuilles, en particulier dans le domaine médical.

2. 发明申请

WO2008037732A1 PLANT CELL LINES ESTABLISHED FROM THE MEDICINAL PLANT VERATRUM CALIFORNICUM 审中-公开
标题翻译：植物细胞系建立在药用植物加热器中
公开(公告)号：WO2008037732A1
公开(公告)日：2008-04-03
申请号：PCT/EP2007/060201
申请日：2007-09-26
申请人： VIB VZW , UNIVERSITEIT GENT , VALTION TEKNILLINEN TUTKIMUSKESKUS , RITALA-NURMI, Anneli , RISCHER, Heiko , OKSMAN-CALDENTEY, Kirsi-Marja , RUI, Ma
发明人： RITALA-NURMI, Anneli , RISCHER, Heiko , OKSMAN-CALDENTEY, Kirsi-Marja , RUI, Ma
IPC分类号： C12N15/04 , A61K36/896 , A01H4/00
CPC分类号： A61K36/896 , A01H4/00
摘要： The present invention relates to the field of plant secondary metabolites. More particularly plant cell lines are established from the medicinal plant Veratrum californicum. Said plant cell lines can be used for the production of cyclopamine and related steroid alkaloids and their precursors.
摘要翻译：本发明涉及植物次生代谢物领域。更特别地，从药用植物藜苜蓿中建立植物细胞系。所述植物细胞系可用于生产环巴胺及相关类固醇生物碱及其前体。

3. 发明申请

US20220290813A1 SYSTEM AND METHOD FOR CRYOGENIC VAPORIZATION WITH PARALLEL VAPORIZER ARRANGEMENTS 有权
公开(公告)号：US20220290813A1
公开(公告)日：2022-09-15
申请号：US17517031
申请日：2021-11-02
申请人： Chao Liang , Seth A. Potratz , Lee J. Rosen , Hanfei Tuo , Rui Ma
发明人： Chao Liang , Seth A. Potratz , Lee J. Rosen , Hanfei Tuo , Rui Ma
IPC分类号： F17C7/04 , F17C13/02
摘要： A cryogenic vaporization system and a method for controlling the system are provided. The system includes a first vaporizer arrangement and a second vaporizer arrangement configured for receiving a liquid cryogen and outputting a superheated vapor. The second vaporizer arrangement is connected in parallel with the first vaporizer arrangement, and includes one or more banks of ambient air vaporizer (AAV) units or loose fill media with a high heat capacity. The second vaporizer arrangement has a different configuration than that of the first vaporizer arrangement. The system further includes at least one control valve controlling provision of the liquid cryogen to at least one of the first vaporizer arrangement and the second vaporizer arrangement.

4. 发明申请

US20220095968A1 SYSTEMS, DEVICES, AND METHODS TO COMPENSATE FOR TEMPERATURE EFFECTS ON SENSORS 有权
公开(公告)号：US20220095968A1
公开(公告)日：2022-03-31
申请号：US17545711
申请日：2021-12-08
申请人： Liang Wang , Shwetha Edla , Ghazaleh R. Esmaili , Hossein Mohammadiarani , Sebastian Bohm , Rui Ma , Minglian Shi , Anna Harley-Trochimczyk
发明人： Liang Wang , Shwetha Edla , Ghazaleh R. Esmaili , Hossein Mohammadiarani , Sebastian Bohm , Rui Ma , Minglian Shi , Anna Harley-Trochimczyk
IPC分类号： A61B5/145 , A61B5/01 , A61B5/1468
摘要： Various examples are directed to systems and methods for generating an estimated analyte value. An analyte sensor system may access a first sensor signal from an in vivo analyte sensor and a first temperature signal from the ex vivo temperature sensor. The analyte sensor system may generate a first analyte sensor temperature based at least in part on the first temperature signal and generate a first estimated analyte value based at least in part on the first sensor signal and the first temperature-compensated sensitivity.

5. 发明申请

US20140004557A1 MICROFLUIDIC DEVICE AND ITS USE FOR POSITIONING OF CELLS OR ORGANISMS 有权
标题翻译：微流体装置及其用于定位细胞或有机物的用途
公开(公告)号：US20140004557A1
公开(公告)日：2014-01-02
申请号：US13991848
申请日：2012-01-13
申请人： Rui Ma , Lan Xie , Tian Qiu , Lei Wang , Wanli Xing
发明人： Rui Ma , Lan Xie , Tian Qiu , Lei Wang , Wanli Xing
IPC分类号： B01L3/00
CPC分类号： B01L3/5027 , C12M21/06 , C12M23/12 , C12M23/16
摘要： A micro fluidic device comprises one microstructure layer (5) and one cover layer (1), wherein the cover layer (1) is connected to the microstructure layer (5). The microstructure layer (5) comprises one bottom layer and a plurality of microstructures on it to position samples. The cover layer (1) comprises one top layer, one positioning well (6) and at least one inlet pool (4). The positioning well (6) is right above the microstructures and connected with each other. The inlet pools (4) and the positioning well (6) are connected by microchannels (3) which are formed between the microstructure layer (5) and the cover layer (1). The micro fluidic device can be applied in vitro fertilization, in determining how glial cells affect neurons, in constructing neural network and in detecting cell growth conditions.
摘要翻译：微流体装置包括一个微结构层（5）和一个覆盖层（1），其中覆盖层（1）连接到微结构层（5）。微结构层（5）包括一个底层和多个微结构，用于定位样品。覆盖层（1）包括一个顶层，一个定位孔（6）和至少一个入口池（4）。定位井（6）位于微结构的正上方并相互连接。入口池（4）和定位井（6）通过形成在微结构层（5）和覆盖层（1）之间的微通道（3）连接。微流体装置可以应用于体外受精，确定神经胶质细胞如何影响神经元，构建神经网络和检测细胞生长条件。

6. 发明授权

US08377889B2 Adiponectin receptor fragments and methods of use 有权
标题翻译：脂联素受体片段和使用方法
公开(公告)号：US08377889B2
公开(公告)日：2013-02-19
申请号：US13211558
申请日：2011-08-17
申请人： Michael Pugia , Rui Ma
发明人： Michael Pugia , Rui Ma
IPC分类号： A61K38/17
CPC分类号： C07K14/72 , A61K38/00
摘要： Methods are disclosed of treating diabetes, abnormal adipocyte activity, and insulin resistance using C-terminal fragments of adiponectin receptor R1. Methods of causing the secretion of insulin in healthy and diabetic patients using C-terminal fragments of adiponectin receptor R1 are also disclosed. In addition, methods are disclosed of increasing the insulin levels in healthy patients using C-terminal fragments of adiponectin receptor R1. In addition, methods of treating abnormal adipocyte activity, treating metabolic syndrome, causing insulin secretion, increasing insulin levels, inhibiting insulin degradation enzyme, treating Alzheimer's disease, treating cardiovascular disease associated with adiponectin levels, inhibiting ADAM-17 enzyme, treating a condition associated with TNF-alpha, and treating a condition associated with HER2-neu are disclosed. Compositions, dosage forms, and kits are also disclosed.
摘要翻译：公开了使用脂联素受体R1的C末端片段治疗糖尿病，异常脂肪细胞活性和胰岛素抵抗的方法。还公开了使用脂联素受体R1的C末端片段在健康和糖尿病患者中分泌胰岛素的方法。此外，公开了使用脂联素受体R1的C末端片段增加健康患者的胰岛素水平的方法。另外，处理异常脂肪细胞活性，治疗代谢综合征，引起胰岛素分泌，增加胰岛素水平，抑制胰岛素降解酶，治疗阿尔茨海默氏病，治疗与脂联素水平相关的心血管疾病，抑制ADAM-17酶，治疗与公开了TNF-α和治疗与HER2-neu相关的病症。还公开了组合物，剂型和试剂盒。

7. 发明申请

US20120069788A1 RANDOM ACCESS METHOD AND BASE STATION 审中-公开
标题翻译：随机访问方法和基站
公开(公告)号：US20120069788A1
公开(公告)日：2012-03-22
申请号：US13256920
申请日：2009-07-27
申请人： Xiaoqin Shen , Rui Ma , Zhongda Du
发明人： Xiaoqin Shen , Rui Ma , Zhongda Du
IPC分类号： H04W74/08
CPC分类号： H04W74/006 , H04B7/2606 , H04W74/0833 , H04W74/0875 , H04W84/047
摘要： A random access method and a base station are provided, wherein the method comprises: a base station assigning a relay-dedicated random access preamble to a relay, wherein the relay-dedicated random access preamble indicates an access priority of the relay to be higher than that of an ordinary UE (S502); the base station receiving the relay-dedicated random access preamble sent from the relay and a random access preamble sent from the ordinary UE (S504); and the base station performing, when determining the relay-dedicated random access preamble is received, a non-contention-based random access preferentially for the relay (S506). Through the above processes, the time taken by random access of the relay to the network can be saved, and the success ratio of random access of the relay to the network is increased.
摘要翻译：提供随机接入方法和基站，其中所述方法包括：向中继分配中继专用随机接入前导码的基站，其中所述中继专用随机接入前导码指示所述中继的接入优先级高于普通UE的（S502）; 接收从中继发送的中继专用随机接入前导码的基站和从普通UE发送的随机接入前导码（S504）; 并且当确定接收到中继专用随机接入前同步码时，基站优先执行用于中继的非基于竞争的随机接入（S506）。通过上述处理，可以节省继电器随机接入网络所需的时间，增加继电器随机接入成功率。

8. 发明申请

US20110301089A1 ADIPONECTIN RECEPTOR FRAGMENTS AND METHODS OF USE 有权
标题翻译： ADIPONECTIN受体片段和使用方法
公开(公告)号：US20110301089A1
公开(公告)日：2011-12-08
申请号：US13211558
申请日：2011-08-17
申请人： Michael J. Pugia , Rui Ma
发明人： Michael J. Pugia , Rui Ma
IPC分类号： A61K38/17 , A61P9/00
CPC分类号： C07K14/72 , A61K38/00
摘要： Methods are disclosed of treating diabetes, abnormal adipocyte activity, and insulin resistance using C-terminal fragments of adiponectin receptor R1. Methods of causing the secretion of insulin in healthy and diabetic patients using C-terminal fragments of adiponectin receptor R1 are also disclosed. In addition, methods are disclosed of increasing the insulin levels in healthy patients using C-terminal fragments of adiponectin receptor R1. In addition, methods of treating abnormal adipocyte activity, treating metabolic syndrome, causing insulin secretion, increasing insulin levels, inhibiting insulin degradation enzyme, treating Alzheimer's disease, treating cardiovascular disease associated with adiponectin levels, inhibiting ADAM-17 enzyme, treating a condition associated with TNF-alpha, and treating a condition associated with HER2-neu are disclosed. Compositions, dosage forms, and kits are also disclosed.
摘要翻译：公开了使用脂联素受体R1的C末端片段治疗糖尿病，异常脂肪细胞活性和胰岛素抵抗的方法。还公开了使用脂联素受体R1的C末端片段在健康和糖尿病患者中分泌胰岛素的方法。此外，公开了使用脂联素受体R1的C末端片段增加健康患者的胰岛素水平的方法。另外，处理异常脂肪细胞活性，治疗代谢综合征，引起胰岛素分泌，增加胰岛素水平，抑制胰岛素降解酶，治疗阿尔茨海默氏病，治疗与脂联素水平相关的心血管疾病，抑制ADAM-17酶，治疗与公开了TNF-α和治疗与HER2-neu相关的病症。还公开了组合物，剂型和试剂盒。

9. 发明申请

US20110231448A1 DEVICE AND METHOD FOR GENERATING OPINION PAIRS HAVING SENTIMENT ORIENTATION BASED IMPACT RELATIONS 有权
标题翻译：用于产生具有基于方向定位的冲击关系的意见对的装置和方法
公开(公告)号：US20110231448A1
公开(公告)日：2011-09-22
申请号：US13053360
申请日：2011-03-22
申请人： Keke Cai , Rui Ma , Zhong Su , Xiao Xun Zhang , Hui Jia Zhu
发明人： Keke Cai , Rui Ma , Zhong Su , Xiao Xun Zhang , Hui Jia Zhu
IPC分类号： G06F17/30
CPC分类号： G06F17/30864 , G06Q30/02
摘要： A device for generating opinion pairs having sentiment orientation based impact relations, having: a reception unit which receives a plurality of object-oriented opinions; an extraction unit which extracts opinions having impact relations among the plurality of object-oriented opinions; an analysis unit which analyzes sentiment orientations of the extracted respective opinions; and a generation unit which establishes correlations between the opinions having sentiment orientation based impact relations to generate the opinion pairs having the sentiment orientation based impact relations. The present device can search and locate more implicit opinions as supplementary opinions by detecting impact relations from a plurality of opinions, and help users interested in different objects obtain more comprehensive comments and summaries.
摘要翻译：一种用于产生具有基于情绪取向的影响关系的意见对的装置，具有：接收多个面向对象意见的接收单元; 提取单元，提取多个面向对象意见之间具有影响关系的意见; 分析单位，分析提取的意见的情绪取向; 并建立了基于情绪导向的影响关系的观点之间的相关性的生成单位，以产生具有基于情绪取向的影响关系的意见对。本设备可以通过检测多个意见的影响关系来搜索和定位更隐含的意见作为补充意见，并帮助对不同对象感兴趣的用户获得更全面的评论和摘要。

10. 发明授权

US08017573B2 Adiponectin receptor fragments and methods of use 有权
标题翻译：脂联素受体片段和使用方法
公开(公告)号：US08017573B2
公开(公告)日：2011-09-13
申请号：US12169983
申请日：2008-07-09
申请人： Michael J. Pugia , Rui Ma
发明人： Michael J. Pugia , Rui Ma
IPC分类号： A61K38/17
CPC分类号： C07K14/72 , A61K38/00
摘要： Methods are disclosed of treating diabetes, abnormal adipocyte activity, and insulin resistance using C-terminal fragments of adiponectin receptor R1. Methods of causing the secretion of insulin in healthy and diabetic patients using C-terminal fragments of adiponectin receptor R1 are also disclosed. In addition, methods are disclosed of increasing the insulin levels in healthy patients using C-terminal fragments of adiponectin receptor R1. In addition, methods of treating abnormal adipocyte activity, treating metabolic syndrome, causing insulin secretion, increasing insulin levels, inhibiting insulin degradation enzyme, treating Alzheimer's disease, treating cardiovascular disease associated with adiponectin levels, inhibiting ADAM-17 enzyme, treating a condition associated with TNF-alpha, and treating a condition associated with HER2-neu are disclosed. Compositions, dosage forms, and kits are also disclosed.
摘要翻译：公开了使用脂联素受体R1的C末端片段治疗糖尿病，异常脂肪细胞活性和胰岛素抵抗的方法。还公开了使用脂联素受体R1的C末端片段在健康和糖尿病患者中分泌胰岛素的方法。此外，公开了使用脂联素受体R1的C末端片段增加健康患者的胰岛素水平的方法。另外，处理异常脂肪细胞活性，治疗代谢综合征，引起胰岛素分泌，增加胰岛素水平，抑制胰岛素降解酶，治疗阿尔茨海默氏病，治疗与脂联素水平相关的心血管疾病，抑制ADAM-17酶，治疗与公开了TNF-α和治疗与HER2-neu相关的病症。还公开了组合物，剂型和试剂盒。

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