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1. 发明授权

US08518884B2 Methods for treating atrial or ventricular arrhythmias by administering a G-protein alpha inhibitor 有权
标题翻译：通过施用G蛋白α抑制剂治疗心房或室性心律失常的方法
公开(公告)号：US08518884B2
公开(公告)日：2013-08-27
申请号：US13476412
申请日：2012-05-21
申请人： Rishi Arora , Gary L. Aistrup
发明人： Rishi Arora , Gary L. Aistrup
IPC分类号： A61K38/00 , A61P9/12 , C07K14/575 , A61K48/00
CPC分类号： A61K38/08 , A61K31/713 , A61K38/1709
摘要： The present invention provides compositions and methods for treating heart conditions. In particular, the present invention provides compositions and methods that block G protein coupled receptor mediated signaling for treating atrial fibrillation.
摘要翻译：本发明提供了治疗心脏病症的组合物和方法。特别地，本发明提供阻断G蛋白偶联受体介导的信号传导治疗心房颤动的组合物和方法。

2. 发明授权

US08326864B2 Method, system, and computer program product for implementing automated worklists 失效
标题翻译：用于实现自动化工作列表的方法，系统和计算机程序产品
公开(公告)号：US08326864B2
公开(公告)日：2012-12-04
申请号：US12254968
申请日：2008-10-21
申请人： Prateek Agrawal , Rishi Arora , Walter C. Dietrich , Regina L. Haecker , Robert Hazeu , Saurabh Singh
发明人： Prateek Agrawal , Rishi Arora , Walter C. Dietrich , Regina L. Haecker , Robert Hazeu , Saurabh Singh
IPC分类号： G06F17/30
CPC分类号： G06Q10/06
摘要： A method, system, and computer program product for implementing automated worklists are provided. The method includes generating a worklist, which further includes retrieving a worklist template corresponding to the worklist and, via a first query, selecting a listing of members and attributes to be populated in the worklist, the attributes include a status indicator of an action item specified for each of the members of the worklist. The worklist generation also includes building a worklist member table with results of the first query and, via a second query, and using attributes of the worklist member table, identifying up-to-date values of one or more worklist member attributes, and outputting results of the second query to the worklist. The method also includes presenting the worklist to a corresponding assignee. For each of the members in the worklist, the status indicator is editable to update a status of the member.
摘要翻译：提供了一种用于实现自动化工作列表的方法，系统和计算机程序产品。该方法包括生成工作列表，其还包括检索与工作列表相对应的工作列表模板，并且经由第一查询选择要在工作列表中填充的成员和属性的列表，所述属性包括指定的操作项的状态指示符为工作清单的每个成员。工作列表生成还包括构建具有第一查询的结果的工作列表成员表，以及通过第二查询，并使用工作列表成员表的属性，识别一个或多个工作列表成员属性的最新值，并输出结果的第二个查询到工作列表。该方法还包括将工作列表呈现给相应的受让人。对于工作列表中的每个成员，状态指示器是可编辑的，以更新成员的状态。

3. 发明授权

US08193151B2 Methods for treating atrial or ventricular arrhythmias 有权
标题翻译：治疗心房或室性心律失常的方法
公开(公告)号：US08193151B2
公开(公告)日：2012-06-05
申请号：US12430595
申请日：2009-04-27
申请人： Rishi Arora , Alan Kadish , Annette Gilchrist
发明人： Rishi Arora , Alan Kadish , Annette Gilchrist
IPC分类号： A61K38/00 , A61K31/00 , A61K48/00 , A61P9/00 , A01N61/00
CPC分类号： A61K31/713 , A61K38/1709
摘要： The present invention provides compositions and methods for treating heart conditions. In particular, the present invention provides compositions and methods that block G protein coupled receptor mediated signaling for treating atrial fibrillation.
摘要翻译：本发明提供了治疗心脏病症的组合物和方法。特别地，本发明提供阻断G蛋白偶联受体介导的信号传导治疗心房颤动的组合物和方法。

4. 发明申请

US20110281853A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING ATRIAL FIBRILLATION 审中-公开
标题翻译：用于治疗或预防ATRIAL FIBRILLATION的组合物和方法
公开(公告)号：US20110281853A1
公开(公告)日：2011-11-17
申请号：US13106618
申请日：2011-05-12
申请人： Rishi Arora , David E. Zembower
发明人： Rishi Arora , David E. Zembower
IPC分类号： A61K31/551 , A61K31/135 , A61K31/404 , A61K31/22 , A61K31/5377 , A61K31/18 , A61K31/24 , A61K31/16 , A61K31/165 , A61K31/352 , A61K31/437 , A61K31/44 , A61K31/522 , A61K31/215 , A61K31/445 , A61K31/4725 , A61K31/4025 , A61K31/4545 , A61P9/06 , A61K31/47
CPC分类号： A61K31/46 , A61K31/132 , A61K31/135 , A61K31/137 , A61K31/138 , A61K31/165 , A61K31/18 , A61K31/215 , A61K31/22 , A61K31/24 , A61K31/352 , A61K31/4025 , A61K31/404 , A61K31/437 , A61K31/44 , A61K31/445 , A61K31/4545 , A61K31/47 , A61K31/4725 , A61K31/522 , A61K31/5377 , A61K31/551 , A61K2300/00
摘要： The present invention provides compositions and methods for treating or preventing atrial fibrillation (AF). In particular, the present invention provides administration of muscarinic receptor antagonists (e.g., M2-selective muscarinic receptor blockers), administered alone or in combination with other therapeutic agents (e.g., beta-adrenergic receptor blockers) to treat and/or prevent atrial fibrillation.
摘要翻译：本发明提供了治疗或预防房颤（AF）的组合物和方法。特别地，本发明提供了单独施用或与其它治疗剂（例如β-肾上腺素能受体阻断剂）组合施用毒蕈碱受体拮抗剂（例如，M2选择性毒蕈碱受体阻断剂）以治疗和/或预防心房颤动。

5. 发明申请

US20110245756A1 DEVICES FOR MATERIAL DELIVERY, ELECTROPORATION, SONOPORATION, AND/OR MONITORING ELECTROPHYSIOLOGICAL ACTIVITY 审中-公开
标题翻译：用于材料交付，电气，电子和/或监测电生理活动的装置
公开(公告)号：US20110245756A1
公开(公告)日：2011-10-06
申请号：US13080755
申请日：2011-04-06
申请人： Rishi Arora , Alan Kadish , Jason Ng
发明人： Rishi Arora , Alan Kadish , Jason Ng
IPC分类号： A61M37/00
CPC分类号： A61N1/327 , A61N1/0412 , A61N1/20
摘要： The invention relates generally to systems and devices for material delivery, energy delivery, and/or monitoring electrophysiological activity, and method of use thereof. In particular, the present invention provides devices and systems, and methods of use thereof, configured to deliver therapeutic compositions, to provide electroporation and/or sonoporation to increase therapeutic efficiency, and to monitor electrophysiological activity, for example, before and after treatment.
摘要翻译：本发明一般涉及用于材料输送，能量输送和/或监测电生理活性的系统和装置及其使用方法。特别地，本发明提供了设备和系统及其使用方法，其被配置为递送治疗组合物，以提供电穿孔和/或超声波以提高治疗效率，以及监测例如治疗前后的电生理活性。

6. 发明申请

US20120329718A1 COMPOSITIONS AND METHODS FOR TREATING ATRIAL FIBRILLATION 有权
标题翻译：用于治疗急性心肌梗塞的组合物和方法
公开(公告)号：US20120329718A1
公开(公告)日：2012-12-27
申请号：US13476412
申请日：2012-05-21
申请人： Rishi Arora , Gary L. Aistrup
发明人： Rishi Arora , Gary L. Aistrup
IPC分类号： A61K38/02 , A61K31/7088 , A61P9/00
CPC分类号： A61K38/08 , A61K31/713 , A61K38/1709
摘要： The present invention provides compositions and methods for treating heart conditions. In particular, the present invention provides compositions and methods that block G protein coupled receptor mediated signaling for treating atrial fibrillation.
摘要翻译：本发明提供了治疗心脏病症的组合物和方法。特别地，本发明提供阻断G蛋白偶联受体介导的信号传导治疗心房颤动的组合物和方法。

7. 发明申请

US20090281019A1 COMPOSITIONS AND METHODS FOR TREATING ATRIAL FIBRILLATION 有权
标题翻译：用于治疗急性心肌梗塞的组合物和方法
公开(公告)号：US20090281019A1
公开(公告)日：2009-11-12
申请号：US12430595
申请日：2009-04-27
申请人： Rishi Arora , Alan Kadish , Annette Gilchrist
发明人： Rishi Arora , Alan Kadish , Annette Gilchrist
IPC分类号： A61K38/16 , A61K31/713 , A61P9/00 , A61P9/06
CPC分类号： A61K31/713 , A61K38/1709
摘要： The present invention provides compositions and methods for treating heart conditions. In particular, the present invention provides compositions and methods that block G protein coupled receptor mediated signaling for treating atrial fibrillation.
摘要翻译：本发明提供了治疗心脏病症的组合物和方法。特别地，本发明提供阻断G蛋白偶联受体介导的信号传导治疗心房颤动的组合物和方法。

8. 发明申请

US20100114926A1 METHOD, SYSTEM, AND COMPUTER PROGRAM PRODUCT FOR IMPLEMENTING AUTOMATED WORKLISTS 失效
标题翻译：实现自动化工作的方法，系统和计算机程序产品
公开(公告)号：US20100114926A1
公开(公告)日：2010-05-06
申请号：US12254968
申请日：2008-10-21
申请人： Prateek Agrawal , Rishi Arora , Walter C. Dietrich , Regina L. Haecker , Robert Hazeu , Saurabh Singh
发明人： Prateek Agrawal , Rishi Arora , Walter C. Dietrich , Regina L. Haecker , Robert Hazeu , Saurabh Singh
IPC分类号： G06F7/00 , G06F7/06 , G06F17/30
CPC分类号： G06Q10/06
摘要： A method, system, and computer program product for implementing automated worklists are provided. The method includes generating a worklist, which further includes retrieving a worklist template corresponding to the worklist and, via a first query, selecting a listing of members and attributes to be populated in the worklist, the attributes include a status indicator of an action item specified for each of the members of the worklist. The worklist generation also includes building a worklist member table with results of the first query and, via a second query, and using attributes of the worklist member table, identifying up-to-date values of one or more worklist member attributes, and outputting results of the second query to the worklist. The method also includes presenting the worklist to a corresponding assignee. For each of the members in the worklist, the status indicator is editable to update a status of the member.
摘要翻译：提供了一种用于实现自动化工作列表的方法，系统和计算机程序产品。该方法包括生成工作列表，其还包括检索与工作列表相对应的工作列表模板，并且经由第一查询选择要在工作列表中填充的成员和属性的列表，所述属性包括指定的操作项的状态指示符为工作清单的每个成员。工作列表生成还包括构建具有第一查询的结果的工作列表成员表，以及通过第二查询，并使用工作列表成员表的属性，识别一个或多个工作列表成员属性的最新值，并输出结果的第二个查询到工作列表。该方法还包括将工作列表呈现给相应的受让人。对于工作列表中的每个成员，状态指示器是可编辑的，以更新成员的状态。

9. 发明申请

US20110137284A1 DEVICES FOR MATERIAL DELIVERY, ELECTROPORATION, AND MONITORING ELECTROPHYSIOLOGICAL ACTIVITY 审中-公开
标题翻译：材料交付，电气和监测电生理活动的设备
公开(公告)号：US20110137284A1
公开(公告)日：2011-06-09
申请号：US12959864
申请日：2010-12-03
申请人： Rishi Arora , Alan Kadish , Jason Ng
发明人： Rishi Arora , Alan Kadish , Jason Ng
IPC分类号： A61N1/30
CPC分类号： A61N1/327
摘要： The invention relates generally to devices for material delivery, electroporation and monitoring electrophysiological activity. In particular, the present invention provides devices and systems configured to deliver therapeutic compositions, to provide electroporation to increase therapeutic efficiency, and to monitor electrophysiological activity, for example, before and after treatment.
摘要翻译：本发明一般涉及用于材料递送，电穿孔和监测电生理活性的装置。特别地，本发明提供了被配置为递送治疗组合物，提供电穿孔以提高治疗效率以及监测电生理活性的装置和系统，例如在治疗之前和之后。

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