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1. 发明授权

US09468755B2 Medical lead with preformed bias 有权
标题翻译：医用铅带有预制偏差
公开(公告)号：US09468755B2
公开(公告)日：2016-10-18
申请号：US12571103
申请日：2009-09-30
申请人： Randy W. Westlund , Mark C. Lynn
发明人： Randy W. Westlund , Mark C. Lynn
IPC分类号： A61N1/05
CPC分类号： A61N1/0558 , A61N1/056 , A61N1/057
摘要： A medical electrical lead and methods of implanting medical electrical leads in lumens. Leads in accordance with the invention employ preformed biases to stabilize the lead within a lumen and to orient electrodes in a preferred orientation.
摘要翻译：一种医用电导线，以及以流明植入医用电线的方法。根据本发明的引线采用预先形成的偏压，以使引线在管腔内稳定并且以优选取向定向电极。

2. 发明授权

US07966076B2 Lead and apparatus for stimulation of the cardiac plexus 失效
标题翻译：用于刺激心脏丛的铅和器械
公开(公告)号：US07966076B2
公开(公告)日：2011-06-21
申请号：US11685511
申请日：2007-03-13
申请人： Randy W. Westlund , Anthony V. Caparso
发明人： Randy W. Westlund , Anthony V. Caparso
IPC分类号： A61N1/05
CPC分类号： A61N1/0553 , A61N1/0558
摘要： A medical electrical lead adapted to stimulate a patient's cardiac plexus includes a flexible distal portion having a surface adapted to conform to an outer surface of an aortic region generally associated with the cardiac plexus. The distal portion can have one or more elongate members. Alternatively, the distal portion can have a generally planar portion. The distal portion is flexible such that it can be furled or otherwise compacted such that it can be delivered to a target stimulation site using a guide catheter or other delivery tool, such as a cannula.
摘要翻译：适于刺激患者心脏丛的医用电线包括柔性远端部分，其具有适于与通常与心脏神经丛相关的主动脉瓣区域的外表面的表面。远端部分可以具有一个或多个细长构件。或者，远端部分可以具有大致平坦的部分。远侧部分是柔性的，使得其可以被卷曲或以其他方式压实，使得其可以使用导管或其它输送工具（例如套管）被输送到目标刺激部位。

3. 发明授权

US07949409B2 Dual spiral lead configurations 有权
标题翻译：双螺旋引线配置
公开(公告)号：US07949409B2
公开(公告)日：2011-05-24
申请号：US11668887
申请日：2007-01-30
申请人： Mark J. Bly , Anthony V. Caparso , Randy W. Westlund , Ronald W. Heil, Jr. , Brendan E. Koop
发明人： Mark J. Bly , Anthony V. Caparso , Randy W. Westlund , Ronald W. Heil, Jr. , Brendan E. Koop
IPC分类号： A61N1/00 , A61B18/04
CPC分类号： A61N1/057 , A61N1/0558 , A61N1/36114
摘要： A medical electrical lead for transvascularly stimulating a nerve, muscle or other tissue from an adjacent vessel is described. The lead includes a bifurcated distal portion including a first elongate member forming a first spiral and a second elongate member forming a second spiral. The spirals can be in parallel or serial alignment with one another.
摘要翻译：描述了用于从相邻容器中经血管刺激神经，肌肉或其他组织的医用电引线。引线包括分叉的远端部分，其包括形成第一螺旋的第一细长构件和形成第二螺旋的第二细长构件。螺旋可以彼此平行或串联对准。

4. 发明申请

US20080183265A1 TRANSVASCULAR LEAD WITH PROXIMAL FORCE RELIEF 审中-公开
标题翻译：具有临时强制救助的横向导弹
公开(公告)号：US20080183265A1
公开(公告)日：2008-07-31
申请号：US11669039
申请日：2007-01-30
申请人： Mark J. Bly , Randy W. Westlund
发明人： Mark J. Bly , Randy W. Westlund
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N1/0573
摘要： A medical electrical lead for implantation in a patient's internal jugular vein at a target location and adjacent a vagus nerve. The lead comprises a proximal region having a proximal stiffness and a distal region. The distal region has a distal stiffness and a first spiral configured to retain the distal region in the internal jugular vein. A transition region is interposed between the proximal and distal regions and has a transitional stiffness. An electrode is coupled to the distal region. The proximal stiffness is less than the distal stiffness so as to reduce an amount of force transferred from the proximal region to the distal region. The transitional stiffness is less than the distal stiffness and greater than the proximal stiffness.
摘要翻译：一种用于在目标位置处植入患者颈内静脉并邻近迷走神经的医用电线。引线包括具有近端刚度和远侧区域的近端区域。远端区域具有远端刚度，第一螺旋构造成将远侧区域保持在颈内静脉内。过渡区域介于近端区域和远端区域之间，具有过渡刚度。电极连接到远端区域。近端刚度小于远端刚度，以便减少从近端区域传递到远端区域的力的量。过渡刚度小于远端刚度，大于近端刚度。

5. 发明申请

US20080183186A1 METHOD AND APPARATUS FOR DELIVERING A TRANSVASCULAR LEAD 审中-公开
标题翻译：用于输送透明导线的方法和装置
公开(公告)号：US20080183186A1
公开(公告)日：2008-07-31
申请号：US11669042
申请日：2007-01-30
申请人： Mark J. Bly , Randy W. Westlund
发明人： Mark J. Bly , Randy W. Westlund
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/36114 , A61N1/372
摘要： A lead delivery system for delivering a medical electrical lead to an internal jugular vein (IJV) through a subclavian vein. An inner catheter extends from a proximal end to a distal end. The inner catheter includes an inner catheter curve configured to direct the distal end to the IJV when positioned in the subclavian vein. The stiffness of the inner catheter decreases in an inner catheter transition region in a direction from the proximal end to the distal end. An outer catheter extends from a proximal end to a distal end and is sized to slide over the inner catheter. The outer catheter includes an outer catheter curve. The stiffness of the outer catheter decreases in an outer catheter transition region in a direction from the proximal end to the distal end. The system further comprises a guidewire having a distal end and a proximal end. The guidewire is sized to slide through the inner catheter to a desired location in the IJV and the guidewire stiffness decreases in a guidewire transition region in a direction from the guidewire proximal end to the guidewire distal end. A method of delivering a medical electrical lead to a target location within an IJV.
摘要翻译：一种用于通过锁骨下静脉将医用电导线输送到颈内静脉（IJV）的引导系统。内导管从近端延伸到远端。内导管包括内导管曲线，其构造成当定位在锁骨下静脉中时将远端引导至IJV。内导管的刚度在从近端到远端的方向上在内导管过渡区域中减小。外导管从近端延伸到远端，并且其尺寸设计成在内导管上滑动。外导管包括外导管曲线。外导管的刚度在从近端到远端的方向上在外导管过渡区域中减小。该系统还包括具有远端和近端的导丝。导丝的尺寸设计成能够通过内导管滑动到IJV中的所需位置，并且导丝刚度在从导丝线近端到导丝线远端的方向上在导丝过渡区域中减小。将医用电导线传送到IJV内的目标位置的方法。

6. 发明授权

US06671560B2 Modified guidewire for left ventricular access lead 失效
标题翻译：修改左心室导线导丝
公开(公告)号：US06671560B2
公开(公告)日：2003-12-30
申请号：US10081436
申请日：2002-02-20
申请人： Randy W. Westlund , Bruce A. Tockman , Randall M. Peterfeso , John S. Greenland , Mary N. Hinders
发明人： Randy W. Westlund , Bruce A. Tockman , Randall M. Peterfeso , John S. Greenland , Mary N. Hinders
IPC分类号： A61N105
CPC分类号： A61N1/057 , A61B2017/22035 , A61M25/09 , A61M2025/09175 , A61N2001/0578
摘要： An improved guidewire for assisting in implantation of a cardiac lead includes three sections. The most distal zone is sufficiently floppy to prevent trauma to the vessel walls through which the guidewire and lead are inserted. An intermediate zone is generally stiffer and has a cross-section less than or equal to the cross-section of the distal zone. The third zone is stiffer yet and is joined to the intermediate zone by a shoulder. The shoulder cooperates with protrusions on the lead to transfer forces between the guidewire and lead. A removal wire having temporary locking device to lock the removal wire to the lead is employed to remove the guide catheter without moving the lead from its desired location. Lubricious coatings are also provided to reduce friction between the lead and guidewire.
摘要翻译：用于辅助植入心脏引线的改进的导线包括三个部分。最远端的区域是足够的软盘，以防止对引导线和引线插入的血管壁的创伤。中间区通常较硬，横截面小于或等于远端区的横截面。第三区域较硬，并通过肩部连接到中间区域。肩部与导线上的突起配合，以在导丝和导线之间传递力。使用具有临时锁定装置以将去除线锁定到引线的去除线去除引导导管而不将引线从其期望位置移动。还提供润滑涂层以减少引线和导丝之间的摩擦。

7. 发明授权

US06356791B1 Modified guidewire for left ventricular access lead 有权
标题翻译：修改左心室导线导丝
公开(公告)号：US06356791B1
公开(公告)日：2002-03-12
申请号：US09466266
申请日：1999-12-17
申请人： Randy W. Westlund , Randall M. Peterfeso , Mary N. Hinders , Bruce A. Tockman , John S. Greenland
发明人： Randy W. Westlund , Randall M. Peterfeso , Mary N. Hinders , Bruce A. Tockman , John S. Greenland
IPC分类号： A61N105
CPC分类号： A61N1/057 , A61B2017/22035 , A61M25/09 , A61M2025/09175 , A61N2001/0578
摘要： An improved guidewire for assisting in implantation of a cardiac lead includes three sections. The most distal zone is sufficiently floppy to prevent trauma to the vessel walls through which the guidewire and lead are inserted. An intermediate zone is generally stiffer and has a cross-section less than or equal to the cross-section of the distal zone. The third zone is stiffer yet and is joined to the intermediate zone by a shoulder. The shoulder cooperates with protrusions on the lead to transfer forces between the guidewire and lead. A removal wire having temporary locking means to lock the removal wire to the lead is employed to remove the guide catheter without moving the lead from its desired location. Lubricious coatings are also provided to reduce friction between the lead and guidewire.
摘要翻译：用于辅助植入心脏引线的改进的导线包括三个部分。最远端的区域是足够的软盘，以防止对引导线和引线插入的血管壁的创伤。中间区通常较硬，横截面小于或等于远端区的横截面。第三区域较硬，并通过肩部连接到中间区域。肩部与导线上的突起配合，以在导丝和导线之间传递力。采用具有将去除线锁定到引线上的临时锁定装置的移除线去除引导导管，而不将引线从其期望的位置移动。还提供润滑涂层以减少引线和导丝之间的摩擦。

8. 发明授权

US06178356B1 Coronary venous lead having fixation mechanism 有权
标题翻译：冠状静脉导管具有固定机制
公开(公告)号：US06178356B1
公开(公告)日：2001-01-23
申请号：US09280128
申请日：1999-03-26
申请人： Stuart A. Chastain , Bruce A. Tockman , Randy W. Westlund , Lili Liu
发明人： Stuart A. Chastain , Bruce A. Tockman , Randy W. Westlund , Lili Liu
IPC分类号： A61N105
CPC分类号： A61N1/057 , A61N2001/0585
摘要： A body implantable lead for placement in a selected coronary vein includes a resilient retention structure for inhibiting displacement of the lead because of heart beat action, breathing or other body movement. The retention structure includes a plurality of resilient projections that are attached to the lead body and which are adapted to project at a predetermined acute angle to the axis of the lead body when unconstrained. Prior to being routed through the vascular system, the projections can be bonded to the lead body to provide a low profile with a biodegradable adhesive. Following exposure to body fluids, the adhesive dissolves, releasing the projections so that they can engage the walls of the vein in which the lead is disposed.
摘要翻译：用于放置在所选择的冠状静脉中的身体可植入引线包括弹性保持结构，用于抑制由于心跳动作，呼吸或其他身体运动引起的位移。保持结构包括多个弹性突起，其附接到引线主体并且适于在不受约束时以与引线主体的轴线成预定的锐角突出。在被引导通过血管系统之前，突起可以结合到引线主体以通过可生物降解的粘合剂提供低轮廓。在暴露于体液后，粘合剂溶解，释放突起使得它们可以与引导物置于其中的静脉的壁接合。

9. 发明授权

US5951597A Coronary sinus lead having expandable matrix anchor 失效
标题翻译：冠状窦导线具有可扩张的基质锚
公开(公告)号：US5951597A
公开(公告)日：1999-09-14
申请号：US59786
申请日：1998-04-14
申请人： Randy W. Westlund , Bruce A. Tockman , Ronald W. Heil, Jr.
发明人： Randy W. Westlund , Bruce A. Tockman , Ronald W. Heil, Jr.
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/0585
摘要： An intravenous lead for use with a cardiac device for implantation in the coronary venous system of the heart includes a lead body that is adapted to be routed through the vascular system into the coronary sinus with the distal end portion of the lead placed in the great cardiac vein or branch vein. The lead body includes a fixation member disposed just proximal of its tip. The fixation member comprises a radially expandable polymeric matrix that incorporates an osmotic agent so that when placed in a aqueous medium it will swell. Thus, when placed in a cardiac vein, the swelling of the fixation member will anchor the lead against longitudinal displacement due to body motion, blood flow and the beating action of the heart.
摘要翻译：用于心脏装置用于植入心脏冠状静脉系统的静脉导管包括引线体，其适于通过血管系统引导到冠状窦中，将引线的远端部分放置在大心脏中静脉或分支静脉。引线体包括设置在其尖端附近的固定部件。固定构件包括可渗透的聚合物基质，其包含渗透剂，使得当放置在水性介质中时，其将溶胀。因此，当放置在心静脉中时，固定构件的肿胀将由于身体运动，血液流动和心脏的打动作用而使引线抵抗纵向移位。

10. 发明授权

US5935154A Implantable tissue stimulator incorporating deposited multilayer capacitor 失效
标题翻译：包含沉积的多层电容器的植入式组织刺激器
公开(公告)号：US5935154A
公开(公告)日：1999-08-10
申请号：US986342
申请日：1997-12-08
申请人： Randy W. Westlund
发明人： Randy W. Westlund
IPC分类号： A61N1/375 , A61N1/39
CPC分类号： A61N1/3956 , A61N1/375
摘要： An implantable tissue stimulator includes a polymer film capacitor adhered to an inside wall surface of the stimulator's case or housing in a way that minimizes the size and weight of the stimulator device. The energy storage capacitor for the tissue stimulator comprises a monolithic, multi-layer device and where the polymer is a suitable acrylate of a known formulation, over 1500 parallel plate capacitor electrodes can be built it with the height dimension of the resulting capacitor being less than about 3 mms. Instead of forming the capacitor on the inner surface of the stimulator's case in situ, such a capacitor can be formed on a mold member corresponding in shape to the inner surface of the stimulator's case and inserted into the stimulator's case following removal from the mold.
摘要翻译：可植入组织刺激器包括以最小化刺激器装置的尺寸和重量的方式粘附到刺激器壳体或壳体的内壁表面的聚合物膜电容器。用于组织刺激器的储能电容器包括单片多层器件，并且其中聚合物是已知配方的合适的丙烯酸酯，其中可以构建超过1500个平行平板电容器电极，其中所得电容器的高度尺寸小于约3公里。代替在现场的刺激器壳体的内表面上形成电容器，这样的电容器可以形成在与激发器壳体的内表面相对应的模具构件上，并且在从模具中移除之后插入刺激器的壳体中。

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