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1. 发明专利

CA2676797C NOVEL MACROMOLECULE TRANSDUCTION DOMAINS AND METHODS FOR IDENTIFICATION AND USES THEREOF 未知
公开(公告)号：CA2676797C
公开(公告)日：2014-04-22
申请号：CA2676797
申请日：2008-01-29
申请人： JO DAE WOONG , KO JAE SUN , KIM JIN SOOK , PARK KYUNG MI , SONG JIN KYUNG , LIM JUNG HEE , DO THI THUY NGA , DO THI LAN PHUONG , DUONG MINH TAM
发明人： JO DAE WOONG , KO JAE SUN , KIM JIN SOOK , PARK KYUNG MI , SONG JIN KYUNG , LIM JUNG HEE , DO THI THUY NGA , DO THI LAN PHUONG , DUONG MINH TAM
IPC分类号： C07K7/04 , C07K7/06 , C07K7/08
摘要： The present invention discloses novel macromolecule transduction domain (MTD) peptides which facilitate the traverse of a biologically active molecule across the cell membrane. Also disclosed are polynucleotides encoding the MTD peptides, methods of identifying the MTD peptides; methods of genetically engineering a biologically active molecule to have cell permeability by using the MTD peptides, methods of importing a biologically active molecule into a cell by using the MTD peptides, and uses thereof.

2. 发明申请

WO2004018426A1 ORGANIC ACID SALT OF AMLODIPINE 审中-公开
标题翻译： AMLODIPINE的有机酸盐
公开(公告)号：WO2004018426A1
公开(公告)日：2004-03-04
申请号：PCT/KR2003/001677
申请日：2003-08-21
申请人： CJ CORP. , YOUN, Yong-Sik , CHO, Seong-Hwan , PARK, Choong-Sil , KIM, Yun-Cheul , LIM, Dong-Kwon , JUNG, Sung-Hak , LEE, Sung-Hak , KANG, Hyun-Suk , PARK, Kyung-Mi , JUNG, Yun-Taek , KIM, Young-Hoon , YEON, Kyu-Jeong , CHAE, Myeong-Yun , JIN, Hae-Tak , SUH, Hea-Ran , LEE, Kwang-Hyeg
发明人： YOUN, Yong-Sik , CHO, Seong-Hwan , PARK, Choong-Sil , KIM, Yun-Cheul , LIM, Dong-Kwon , JUNG, Sung-Hak , LEE, Sung-Hak , KANG, Hyun-Suk , PARK, Kyung-Mi , JUNG, Yun-Taek , KIM, Young-Hoon , YEON, Kyu-Jeong , CHAE, Myeong-Yun , JIN, Hae-Tak , SUH, Hea-Ran , LEE, Kwang-Hyeg
IPC分类号： C07D211/90
CPC分类号： C07D211/90
摘要： Disclosed are a novel organic acid salt of amlodipine, its preparation method, and a pharmaceutical composition containing the same as a therapeutically active ingredient.
摘要翻译：公开了氨氯地平的新型有机酸盐，其制备方法和含有它作为治疗活性成分的药物组合物。

3. 发明申请

WO2004011435A1 ORGANIC ACID SALT OF AMLODIPINE 审中-公开
标题翻译：有机酸亚麻酸盐
公开(公告)号：WO2004011435A1
公开(公告)日：2004-02-05
申请号：PCT/KR2003/001524
申请日：2003-07-30
申请人： CJ CORP. , CHO, Seong-Hwan , YOUN, Yong-Sik , JUNG, Yun-Taek , PARK, Choong-Sil , LEE, Hyuk-Koo , LEE, Kwang-Hyeg , JEONG, Eun-Ju , KIM, Young-Hoon , JIN, Hae-Tak , CHEON, Jun-Hee , LEE, Sung-Hak , JUNG, Sung-Hak , LIM, Dong-Kwon , YEON, Kyu-Jeong , KIM, Yun-Cheul , PARK, Kyung-Mi , KANG, Hyun-Suk
发明人： CHO, Seong-Hwan , YOUN, Yong-Sik , JUNG, Yun-Taek , PARK, Choong-Sil , LEE, Hyuk-Koo , LEE, Kwang-Hyeg , JEONG, Eun-Ju , KIM, Young-Hoon , JIN, Hae-Tak , CHEON, Jun-Hee , LEE, Sung-Hak , JUNG, Sung-Hak , LIM, Dong-Kwon , YEON, Kyu-Jeong , KIM, Yun-Cheul , PARK, Kyung-Mi , KANG, Hyun-Suk
IPC分类号： C07D211/90
CPC分类号： C07D211/90
摘要： Disclosed are a novel organic salt of amlodipine, its preparation method, and a pharmaceutical composition containing as a therapeutically active ingredient the same.
摘要翻译：公开了一种新的氨氯地平有机盐，其制备方法和含有作为治疗活性成分的药物组合物。

4. 发明申请

WO2004011434A1 ORGANIC ACID SALT OF AMLODIPINE 审中-公开
标题翻译：有机酸亚麻酸盐
公开(公告)号：WO2004011434A1
公开(公告)日：2004-02-05
申请号：PCT/KR2003/001525
申请日：2003-07-30
申请人： CJ CORP. , CHO, Seong-Hwan , YOUN, Yong-Sik , JUNG, Yun-Taek , PARK, Choong-Sil , LEE, Hyuk-Koo , LEE, Kwang-Hyeg , JEONG, Eun-Ju , KIM, Young-Hoon , JIN, Hae-Tak , CHEON, Jun-Hee , LEE, Sung-Hak , JUNG, Sung-Hak , LIM, Dong-Kwon , YEON, Kyu-Jeong , KIM, Yun-Cheul , PARK, Kyung-Mi , KANG, Hyun-Suk
发明人： CHO, Seong-Hwan , YOUN, Yong-Sik , JUNG, Yun-Taek , PARK, Choong-Sil , LEE, Hyuk-Koo , LEE, Kwang-Hyeg , JEONG, Eun-Ju , KIM, Young-Hoon , JIN, Hae-Tak , CHEON, Jun-Hee , LEE, Sung-Hak , JUNG, Sung-Hak , LIM, Dong-Kwon , YEON, Kyu-Jeong , KIM, Yun-Cheul , PARK, Kyung-Mi , KANG, Hyun-Suk
IPC分类号： C07D211/86
CPC分类号： C07D211/90
摘要： Disclosed are a novel organic acid salt of amlodipine with superb physicochemical properties, its preparation method, and a pharmaceutical composition containing the same as a therapeutically active ingredient.
摘要翻译：公开了具有极好物理化学性质的氨氯地平的新型有机酸盐及其制备方法以及含有其作为治疗活性成分的药物组合物。

5. 发明申请

WO2004011433A1 ORGANIC ACID SALT OF AMLODIPINE 审中-公开
标题翻译：有机酸亚麻酸盐
公开(公告)号：WO2004011433A1
公开(公告)日：2004-02-05
申请号：PCT/KR2003/001523
申请日：2003-07-30
申请人： CJ CORP. , CHO, Seong-Hwan , YOUN, Yong-Sik , JUNG, Yun-Taek , PARK, Choong-Sil , LEE, Hyuk-Koo , LEE, Kwang-Hyeg , JEONG, Eun-Ju , KIM, Young-Hoon , JIN, Hae-Tak , CHEON, Jun-Hee , LEE, Sung-Hak , JUNG, Sung-Hak , LIM, Dong-Kwon , YEON, Kyo-Jeong , KIM, Yun-Cheul , PARK, Kyung-Mi , KANG, Hyun-Suk
发明人： CHO, Seong-Hwan , YOUN, Yong-Sik , JUNG, Yun-Taek , PARK, Choong-Sil , LEE, Hyuk-Koo , LEE, Kwang-Hyeg , JEONG, Eun-Ju , KIM, Young-Hoon , JIN, Hae-Tak , CHEON, Jun-Hee , LEE, Sung-Hak , JUNG, Sung-Hak , LIM, Dong-Kwon , YEON, Kyo-Jeong , KIM, Yun-Cheul , PARK, Kyung-Mi , KANG, Hyun-Suk
IPC分类号： C07D211/86
CPC分类号： C07D211/90
摘要： Disclosed are a novel organic salt of amlodipine, its preparation method, and a pharmaceutical composition containing the same as a therapeutically active ingredient.
摘要翻译：公开了一种新的氨氯地平有机盐，其制备方法和含有其作为治疗活性成分的药物组合物。

6. 发明申请

WO2004011432A1 ORGANIC ACID SALT OF AMLODIPINE 审中-公开
标题翻译：有机酸亚麻酸盐
公开(公告)号：WO2004011432A1
公开(公告)日：2004-02-05
申请号：PCT/KR2003/001522
申请日：2003-07-30
申请人： CJ CORP. , CHO, Seong-Hwan , YOUN, Yong-Sik , JUNG, Yun-Taek , PARK, Choong-Sil , LEE, Hyuk-Koo , LEE, Kwang-Hyeg , JEONG, Eun-Ju , KIM, Young-Hoon , CHEON, Jun-Hee , JIN, Hae-Tak , LEE, Sung-Hak , JUNG, Sung-Hak , LIM, Dong-Kwon , YEON, Kyu-Jeong , KIM, Yun-Cheul , PARK, Kyung-Mi , KANG, Hyun-Suk
发明人： CHO, Seong-Hwan , YOUN, Yong-Sik , JUNG, Yun-Taek , PARK, Choong-Sil , LEE, Hyuk-Koo , LEE, Kwang-Hyeg , JEONG, Eun-Ju , KIM, Young-Hoon , CHEON, Jun-Hee , JIN, Hae-Tak , LEE, Sung-Hak , JUNG, Sung-Hak , LIM, Dong-Kwon , YEON, Kyu-Jeong , KIM, Yun-Cheul , PARK, Kyung-Mi , KANG, Hyun-Suk
IPC分类号： C07D211/86
CPC分类号： C07D211/90
摘要： Disclosed are a novel organic acid salt of amlodipine, its preparation method, and a pharmaceutical composition containing the same as a therapeutically active ingredient.
摘要翻译：公开了一种新型的氨氯地平有机酸盐及其制备方法和含有其作为治疗活性成分的药物组合物。

7. 发明申请

WO2009066806A1 PURIFICATION METHOD OF HUMAN ERYTHROPOIETIN 审中-公开
标题翻译：人类精神病药物的纯化方法
公开(公告)号：WO2009066806A1
公开(公告)日：2009-05-28
申请号：PCT/KR2007/005898
申请日：2007-11-22
申请人： KOREA RESEARCH INSTITUTE OF BIOSCIENCE & BIOTECHNOLOGY , RURAL DEVELOPMENT ADMINISTRATION , CHUNG, Bong Hyun , LEE, Eun Gyo , JUNG, Joon Ki , PARK, Kyung Mi , LEE, Seung Hui , BAEK, Jung Eun , CHANG, Won Kyong , PARK, Jin Ki
发明人： CHUNG, Bong Hyun , LEE, Eun Gyo , JUNG, Joon Ki , PARK, Kyung Mi , LEE, Seung Hui , BAEK, Jung Eun , CHANG, Won Kyong , PARK, Jin Ki
IPC分类号： C07K14/775 , C07K1/14
CPC分类号： C07K14/505
摘要： The present invention discloses the a method of purifying human erythropoietin, the method of the present invention comprises the steps of (1) purifying a cell culture or pretreated milk of a transgenic animal by heparin chromatography, (2) purifying a fraction containing human erythropoietin obtained from the step (1) by re versed-phase chromatography, and (3) purifying a fraction containing human erythropoietin obtained from the step (2) by gel filtration chromatography. When human erythropoietin is purified from milk of a transgenic animal, the milk of the transgenic animal is pretreated before performing the step (1), and this pretreatment process comprises the steps of (a) recovering a supernatant from the milk of the transgenic animal by centrifugation, (b) adding a first precipitating agent to the supernatant for first precipitation of impurities, (c) adding a transition metal ion for second precipitation of impurities, and (d) ultrafiltering the supernatant recovered from the step (c).
摘要翻译：本发明公开了一种纯化人促红细胞生成素的方法，本发明的方法包括以下步骤：（1）通过肝素色谱纯化转基因动物的细胞培养物或预处理乳，（2）纯化得到的含有促红细胞生成素的级分通过反相层析从步骤（1）中，和（3）通过凝胶过滤色谱纯化由步骤（2）获得的含有促红细胞生成素的级分。当人类促红细胞生成素从转基因动物的乳中纯化时，在进行步骤（1）之前，对转基因动物的乳进行预处理，该预处理过程包括以下步骤：（a）通过以下步骤：（a）从转基因动物的乳中回收上清液，离心，（b）将第一沉淀剂加入到上清液中用于首先沉淀杂质，（c）加入过渡金属离子用于第二次沉淀杂质，和（d）超滤从步骤（c）中回收的上清液。

8. 发明申请

WO2008093982A1 NOVEL MACROMOLECULE TRANSDUCTION DOMAINS AND METHODS FOR IDENTIFICATION AND USES THEREOF 审中-公开
标题翻译：新型MACROMOLECULE传输域及其识别方法及其应用
公开(公告)号：WO2008093982A1
公开(公告)日：2008-08-07
申请号：PCT/KR2008/000525
申请日：2008-01-29
申请人： INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY , JO, Dae Woong , KO, Jae Sun , KIM, Jin Sook , PARK, Kyung Mi , SONG, Jin Kyung , LIM, Jung Hee , DO, Thi Thuy Nga , DO, Thi Lan Phuong , DUONG, Minh Tam
发明人： JO, Dae Woong , KO, Jae Sun , KIM, Jin Sook , PARK, Kyung Mi , SONG, Jin Kyung , LIM, Jung Hee , DO, Thi Thuy Nga , DO, Thi Lan Phuong , DUONG, Minh Tam
IPC分类号： C07K7/04 , C07K7/06 , C07K7/08
CPC分类号： A61K47/48246 , A61K39/39 , A61K48/0041 , C07K7/06 , C07K7/08 , C07K14/195 , C07K14/47
摘要： The present invention discloses novel macromolecule transduction domain (MTD) peptides which facilitate the traverse of a biologically active molecule across the cell membrane. Also disclosed are polynucleotides encoding the MTD peptides, methods of identifying the MTD peptides; methods of genetically engineering a biologically active molecule to have cell permeability by using the MTD peptides, methods of importing a biologically active molecule into a cell by using the MTD peptides, and uses thereof.
摘要翻译：本发明公开了促进细胞膜上生物活性分子穿越的新型大分子转导结构域（MTD）肽。还公开了编码MTD肽的多核苷酸，鉴定MTD肽的方法; 通过使用MTD肽将生物活性分子遗传工程化以具有细胞渗透性的方法，通过使用MTD肽将生物活性分子导入细胞的方法及其用途。

9. 发明申请

WO2008069583A1 APPARATUS AND METHOD OF TRANSMITTING/RECEIVING SIGNALS USING SIGNALING POINT ROTATION AT MUTUAL COOPERATION TRANSMISSION 审中-公开
标题翻译：在相互合作传输中使用信号点旋转的发送/接收信号的装置和方法
公开(公告)号：WO2008069583A1
公开(公告)日：2008-06-12
申请号：PCT/KR2007/006294
申请日：2007-12-06
申请人： ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE , LEE, Hyojin , CHUNG, Hyun-Kyu , RYU, Hyun-Seok , KANG, Chung-Gu , LEE, Heesoo , PARK, Kyung-Mi
发明人： LEE, Hyojin , CHUNG, Hyun-Kyu , RYU, Hyun-Seok , KANG, Chung-Gu , LEE, Heesoo , PARK, Kyung-Mi
IPC分类号： H04L27/36
CPC分类号： H04L27/34 , H04B7/02 , H04B7/026 , H04B7/15592 , H04L27/36 , H04L27/38
摘要： An apparatus for and method of transmitting and/or receiving a signal by using signaling point rotation in mutually cooperative relaying are provided. The apparatus for transmitting a signal includes: a rotated I-channel generation unit rotating a symbol containing data of a first user, by a predetermined angle, and then, obtaining the I-channel (in-phase) component of the rotated symbol; a rotated Q-channel generation unit receiving a symbol rotated by a predetermined angle, of a previous time slot from a node of a second user performing mutually cooperative relaying with the node of the first user, detecting the I-channel component, and obtaining the Q-channel (quadrature-phase) component of a symbol containing data of the second user from the detected I-channel component; and a combining unit combining the I-channel component of the first user generated in the rotated I-channel generation unit and the Q-channel component of the second user generated in the rotated Q-channel generation unit, thereby generating one symbol.
摘要翻译：提供了一种通过在相互协作的中继中使用信令点旋转来发送和/或接收信号的装置和方法。用于发送信号的装置包括：旋转的I信道生成单元，使包含第一用户的数据的符号旋转预定角度，然后获得旋转符号的I信道（同相）分量; 旋转的Q信道生成单元接收从与第一用户的节点进行相互协作中继的第二用户的节点的先前时隙旋转预定角度的符号，检测I信道分量，并获得从检测到的I信道分量的包含第二用户的数据的符号的Q信道（正交相位）分量; 以及组合单元，组合在旋转的I信道生成单元中生成的第一用户的I信道分量和在旋转的Q信道生成单元中生成的第二用户的Q信道分量，从而生成一个符号。

10. 发明公开

KR20120076012A A apparatus for manufacturing sole of shoes and manufacturing method using thereof 有权
标题翻译：用于制造鞋子及其制造方法的装置
公开(公告)号：KR20120076012A
公开(公告)日：2012-07-09
申请号：KR20100137968
申请日：2010-12-29
申请人： PARK KYUNG MI
发明人： PARK KYUNG MI
IPC分类号： A43B13/12 , B29C45/16
CPC分类号： B29D35/128 , A43B13/12 , B29C45/16 , B29C45/26 , B29D35/122
摘要： PURPOSE: A device for manufacturing an outsole and a method for manufacturing an outsole using the same are provided to manufacture the center and edge of the outsole using different materials. CONSTITUTION: A device for manufacturing an outsole comprises a lower mold(20), a first upper mold(30), a second upper mold(40), a secondary upper mold(50). The lower mold forms a central shaping hole and a circumference shaping hole in order to shape the center and circumference of the outsole. The first upper mold is combined with the central shaping hole and forms the center of the outsole. The second upper mold is combined with the circumference shaping hole and forms the circumference of the outsole.
摘要翻译：目的：提供一种用于制造外底的装置和使用该外底的外底制造方法，以使用不同的材料制造外底的中心和边缘。构成：用于制造外底的装置包括下模具（20），第一上模具（30），第二上模具（40）和次上模具（50）。下模具形成中心成形孔和圆周成形孔，以形成外底的中心和周长。第一上模具与中心成形孔结合形成外底的中心。第二上模与圆周成形孔结合，形成外底的圆周。

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