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1. 发明授权

US07771769B2 Flavouring a foodstuff by incorporating an effective amount of at least one compound of the formula R1-S-R2 in which R1 and R2 represent a specific atom or group 有权
标题翻译：通过加入有效量的至少一种式R1-S-R2的化合物来调味食品，其中R1和R2代表特定的原子或基团
公开(公告)号：US07771769B2
公开(公告)日：2010-08-10
申请号：US10240772
申请日：2001-04-05
申请人： Wolfgang Fitz , Josef Kerler , Harry Renes , Nico Bouter
发明人： Wolfgang Fitz , Josef Kerler , Harry Renes , Nico Bouter
IPC分类号： A23L1/22
CPC分类号： C07D277/34 , A23L27/2022 , A23L27/205 , C07C321/08 , C07C321/14 , C07C321/18 , C07C323/41 , C07C327/22 , C07C327/30
摘要： NEW MATERIAL: A compound of formula I (R is 1˜6C alkyl other than ethyl, 2˜6C alkenyl).EXAMPLE: 2-Methyl 2-mercaptopropionate.USE: A durable flavor and taste imparting agent usable for foods, drinks, cosmetics, healthy and hygienic use, medicines, etc.PROCESS: A 2-mercaptopropionic acid of formula II (R′ is H, 1˜6C alkyl or 2˜6C alkenyl) is esterified with an aliphatic alcohol of the formula R′(OH) in the presence of a catalyst, e.g. an inorganic acid such as sulfuric acid or organic acid such as acetic acid, in an azeotropic solvent, e.g. benzene, at 60˜100° C. to give the compound of formula I easily in high purity and yield. The molar amount of the aliphatic alcohol to be used is 1˜20 times, preferably 2˜5 times, that of the compound of formula II. The amount of the catalyst to be used is 0.1˜10 wt % based on the compound of formula II.
摘要翻译：新材料：式I化合物（R是除乙基以外的1〜6C烷基，2〜6C烯基）。实施例：2-巯基丙酸2-甲酯。用途：可用于食品，饮料，化妆品，健康和卫生用途，药物等的耐用味道和味道赋予剂。方法：式II的2-巯基丙酸（R'是H，1〜6C烷基或2〜6C 烯基）在催化剂存在下用式R'（OH）的脂族醇酯化，例如无机酸如硫酸或有机酸如乙酸，在共沸溶剂例如乙酸中。苯，在60〜100℃下，以高纯度容易地得到式I化合物，产率。所使用的脂族醇的摩尔量为式II化合物的摩尔量的1〜20倍，优选2〜5倍。催化剂的使用量相对于式II化合物为0.1〜10重量％。

2. 发明授权

US07862844B2 Taste improving substances 有权
标题翻译：滋味改善物质
公开(公告)号：US07862844B2
公开(公告)日：2011-01-04
申请号：US11815233
申请日：2005-10-06
申请人： Chris Winkel , Harry Renes , Jan Visser , Nico Bouter , Jan Bakker , Bart Ruisch
发明人： Chris Winkel , Harry Renes , Jan Visser , Nico Bouter , Jan Bakker , Bart Ruisch
IPC分类号： A23L1/226 , A23L1/229
CPC分类号： A23L27/23
摘要： The present invention in a first aspect relates to taste improvement of foodstuffs, beverages, pharmaceutics, tobacco products and oral care products, using extremely small amounts of a substance according to formula (I), or edible salts thereof: R1—CR2(OR3)—CO—X (I). It was found that at very low concentrations, substances represented by formula (I) are capable of modifying and complementing, the sensory impact of taste imparting substances. Thus, the present taste improving substances are advantageously applied in flavour compositions, foodstuffs, pharmaceutics, tobacco products and oral care products. Typical examples of taste improving substances according to the present invention include N-lactoyl GMP, N-lactoyl AMP, N-lactoyl CMP, N-lactoyl IMP, N-gluconyl GMP, N-gluconyl AMP, N-gluconyl CMP, N-gluconyl IMP, O-lactoyl-GMP, O-lactoyl AMP, O-lactoyl CMP, O-lactoyl IMP, O-gluconyl GMP, O-gluconyl AMP, O-gluconyl CMP and O-gluconyl IMP and mixtures thereof.
摘要翻译：本发明的第一方面涉及使用极少量根据式（I）的物质或食用盐的食品，饮料，药物，烟草制品和口腔护理产品的味道改进：R1-CR2（OR3） -CO-X（I）。发现在非常低的浓度下，由式（I）表示的物质能够改变和补充味道赋予物质的感官影响。因此，本发明的味道改善物质有利地用于风味组合物，食品，药物，烟草制品和口腔护理产品中。根据本发明的味道改善物质的典型实例包括N-乳酰基GMP，N-乳酰基AMP，N-乳酰基CMP，N-乳酰基IMP，N-葡萄糖基GMP，N-葡萄糖基AMP，N-葡萄糖基酰基CMP，N-葡萄糖基 IMP，O-乳酰基-GMP，O-乳酰基AMP，O-乳酰基CMP，O-乳酰基IMP，O-葡萄糖基GMP，O-葡萄糖基AMP，O-葡萄糖基酰基CMP和O-葡萄糖基IMP及其混合物。

3. 发明申请

US20100143563A1 FLAVOURING A FOODSTUFF BY INCORPORATING AN EFFECTIVE AMOUNT OF AT LEAST ONE COMPOUND OF THE FORMULA R1-S-R2 IN WHICH R1 AND R2 REPRESENT A SPECIFIC ATOM OR GROUP 审中-公开
标题翻译：通过加入至少一种R1-R2的化合物的有效量来表达食品，其中R1和R2表示特定的原子或基团
公开(公告)号：US20100143563A1
公开(公告)日：2010-06-10
申请号：US12608347
申请日：2009-10-29
申请人： Wolfgang FITZ , Josef Kerler , Harry Renes , Nico Bouter
发明人： Wolfgang FITZ , Josef Kerler , Harry Renes , Nico Bouter
IPC分类号： A23L1/226
CPC分类号： C07D277/34 , A23L27/2022 , A23L27/205 , C07C321/08 , C07C321/14 , C07C321/18 , C07C323/41 , C07C327/22 , C07C327/30
摘要： A process for flavouring foodstuffs includes incorporating therein a flavoring effective amount of at least one compound represented by R1-S-R2 wherein R1 and R2 represent (a) a hydrogen atom and a 1-(1-methoxycarbonyl)ethyl group or represent (b) a hydrogen atom and a 1-(1-propyloxycarbonyl)ethyl group. Foodstuffs and concentrates containing at least one of the R1-S-R2 compounds are provided.
摘要翻译：调味食品的方法包括在其中加入调味有效量的至少一种由R 1 -S-R 2表示的化合物，其中R 1和R 2表示（a）氢原子和1-（1-甲氧基羰基）乙基或代表（b ）氢原子和1-（1-丙氧基羰基）乙基。提供含有至少一种R1-S-R2化合物的食品和浓缩物。

4. 发明申请

US20080131573A1 Taste Improving Substances 有权
标题翻译：味道改善物质
公开(公告)号：US20080131573A1
公开(公告)日：2008-06-05
申请号：US11815233
申请日：2005-10-06
申请人： Chris Winkel , Harry Renes , Jan Visser , Nico Bouter , Jan Bakker , Bart Ruisch
发明人： Chris Winkel , Harry Renes , Jan Visser , Nico Bouter , Jan Bakker , Bart Ruisch
IPC分类号： A23L1/226 , A23L1/229
CPC分类号： A23L27/23
摘要： The present invention in a first aspect relates to taste improvement of foodstuffs, beverages, pharmaceutics, tobacco products and oral care products, using extremely small amounts of a substance according to formula (I), or edible salts thereof: R1—CR2(OR3)—CO—X (I). It was found that at very low concentrations, substances represented by formula (I) are capable of modifying and complementing, the sensory impact of taste imparting substances. Thus, the present taste improving substances are advantageously applied in flavour compositions, foodstuffs, pharmaceutics, tobacco products and oral care products. Typical examples of taste improving substances according to the present invention include N-lactoyl GMP, N-lactoyl AMP, N-lactoyl CMP, N-lactoyl IMP, N-gluconyl GMP, N-gluconyl AMP, N-gluconyl CMP, N-gluconyl IMP, O-lactoyl-GMP, O-lactoyl AMP, O-lactoyl CMP, O-lactoyl IMP, O-gluconyl GMP, O-gluconyl AMP, O-gluconyl CMP and O-gluconyl IMP and mixtures thereof.
摘要翻译：本发明的第一方面涉及使用极少量根据式（I）的物质或其可食用盐的食品，饮料，药物，烟草制品和口腔护理产品的味道改进：R 1，（OR 3）-OC-X（I）。发现在非常低的浓度下，由式（I）表示的物质能够改变和补充味道赋予物质的感官影响。因此，本发明的味道改善物质有利地用于风味组合物，食品，药物，烟草制品和口腔护理产品中。根据本发明的味道改善物质的典型实例包括N-乳酰基GMP，N-乳酰基AMP，N-乳酰基CMP，N-乳酰基IMP，N-葡萄糖基GMP，N-葡萄糖基AMP，N-葡萄糖基酰基CMP，N-葡萄糖基 IMP，O-乳酰基-GMP，O-乳酰基AMP，O-乳酰基CMP，O-乳酰基IMP，O-葡萄糖基GMP，O-葡萄糖基AMP，O-葡萄糖基酰基CMP和O-葡萄糖基IMP及其混合物。

5. 发明授权

US07981457B2 Taste improving substances 有权
标题翻译：滋味改善物质
公开(公告)号：US07981457B2
公开(公告)日：2011-07-19
申请号：US11578443
申请日：2005-04-06
申请人： Jan Visser , Harry Renes , Chris Winkel , Nico Bouter
发明人： Jan Visser , Harry Renes , Chris Winkel , Nico Bouter
IPC分类号： A23L1/226 , A23L1/229
CPC分类号： A23L27/23 , A23L27/2054
摘要： The present invention in a first aspect relates to taste improvement of foodstuffs, beverages, pharmaceutics, tobacco products and oral care products, using a substance according to formula (I), or edible salts thereof: formula (I): R1—CR2(OR3)—CO—X. It was found that substances represented by formula (I) are capable of modifying and complementing, the sensory impact of taste imparting substances. Thus, the present taste improving substances are advantageously applied in flavour compositions, foodstuffs, pharmaceuticals, tobacco products and oral care products. Typical examples of taste improving substances according to the present invention include N-lactoyl GMP, N-lactoyl AMP, N-lactoyl CMP, N-lactoyl IMP, N-gluconyl GMP, N-gluconyl AMP, N-gluconyl CMP, N-gluconyl IMP, O-lactoyl-GMP, O-lactoyl AMP, O-lactoyl CMP, O-lactoyl IMP, O-gluconyl GMP, N-gluconyl AMP, O-gluconyl CMP and O-gluconyl IMP and the mixtures thereof.
摘要翻译：本发明的第一方面涉及使用根据式（I）的物质的食品，饮料，药物，烟草制品和口腔护理产品的味道改善或其食用盐：式（I）：R1-CR2（OR3 ）-CO-X。发现由式（I）表示的物质能够改变和补充味道赋予物质的感官影响。因此，本发明的味道改善物质有利地应用于风味组合物，食品，药物，烟草制品和口腔护理产品中。根据本发明的味道改善物质的典型实例包括N-乳酰基GMP，N-乳酰基AMP，N-乳酰基CMP，N-乳酰基IMP，N-葡萄糖基GMP，N-葡萄糖基AMP，N-葡萄糖基酰基CMP，N-葡萄糖基 IMP，O-乳酰基-GMP，O-乳酰基AMP，O-乳酰基CMP，O-乳酰基IMP，O-葡萄糖基GMP，N-葡萄糖基AMP，O-葡萄糖基酰基CMP和O-葡萄糖酸基IMP及其混合物。

6. 发明申请

US20080038430A1 Taste Improving Substances 有权
标题翻译：味道改善物质
公开(公告)号：US20080038430A1
公开(公告)日：2008-02-14
申请号：US11578443
申请日：2005-04-06
申请人： Jan Visser , Harry Renes , Chris Winkel , Nico Bouter
发明人： Jan Visser , Harry Renes , Chris Winkel , Nico Bouter
IPC分类号： A23L1/226 , A23L1/229
CPC分类号： A23L27/23 , A23L27/2054
摘要： The present invention in a first aspect relates to taste improvement of foodstuffs, beverages, pharmaceutics and oral care products, using a compound according to formula (I), or edible salts thereof: R1—CR2(OR3)—CO—X (I). It was found that compounds represented by formula (I) are capable of modifying, especially enhancing, the sensory impact of taste imparting substances. Thus, the present taste modifying compounds are advantageously applied in flavour compositions, foodstuffs and oral care products. Typical examples of flavour modifying compounds according to the present invention include N-lactoyl guano sine monophosphate (GMP), N-lactoyl adenosine monophosphate (AMP), N-lactoyl cytosine monophosphate (CMP), N-lactoyl inosine monophosphate (IMP), N-gluconyl GMP, N-gluconyl AMP, N-gluconyl CMP and N-gluconyl IMP.
摘要翻译：本发明的第一方面涉及使用根据式（I）的化合物或其食用盐的食品，饮料，药物和口腔护理产品的味道改善：<？在线配方描述=“在线公式“end =”lead“？> R 1 -CR 2（或3）-CO-X（I）。发现由式（I）表示的化合物能够改变，特别是增强味觉赋予物质的感官影响。因此，本发明的调味化合物有利地应用于风味组合物，食品和口腔护理产品中。根据本发明的风味改良化合物的典型实例包括N-乳酰基鸟苷一磷酸（GMP），N-乳酰基腺苷一磷酸（AMP），N-乳酰基胞嘧啶一磷酸（CMP），N-乳酰肌苷一磷酸（IMP），N - 葡萄糖基GMP，N-葡萄糖基AMP，N-葡萄糖基酰基CMP和N-葡萄糖基IMP。

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