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1. 发明授权

US09596874B2 Bitter taste masking compositions and method of masking bitter taste 有权
公开(公告)号：US09596874B2
公开(公告)日：2017-03-21
申请号：US13989107
申请日：2011-11-30
申请人： Gesa Haseleu , Elisabetta Lubian , Harry Renes , Cornelis Winkel
发明人： Gesa Haseleu , Elisabetta Lubian , Harry Renes , Cornelis Winkel
IPC分类号： A23L1/22
CPC分类号： A23C9/1544 , A23L27/202 , A23L27/2026 , A23L27/40 , A23L27/86 , A23L27/88
摘要： A composition for masking the bitter taste of potassium chloride or other potassium salt used in a consumable product as a substitute, in whole or in part, for common table salt, said composition comprising a sugar alcohol and a compound of formula (I) CH2OH—(CHOH)4—CO—NH—CH2—CH2—X; a compound of the formula (II): R1—CR2(OR3)—CO—Y; or a mixture thereof.

2. 发明授权

US08778437B2 Taste improving substances 有权
标题翻译：滋味改善物质
公开(公告)号：US08778437B2
公开(公告)日：2014-07-15
申请号：US11578846
申请日：2005-04-06
申请人： Harry Renes , Chris Winkel , Caroline De Lamarliere , Thorsten König , Esther Van Ommeren , Sander Tondeur
发明人： Harry Renes , Chris Winkel , Caroline De Lamarliere , Thorsten König , Esther Van Ommeren , Sander Tondeur
IPC分类号： A23L1/226
CPC分类号： A23L27/21 , A23L27/202
摘要： The present invention in a first aspect relates to taste improvement of foodstuffs, beverages, pharmaceutics, tobacco products and oral care products, using a substance according to formula (I) or formula (II), or edible salts thereof: R1—CR7(OR4)—CO—NR2—CR8R3—X—OR5 (I) R6—CR7(OR4)—CO-Az (II) It was found that substances represented by formula (I) and/or formula (II) are capable of modulating and complementing the sensory impact of taste imparting substances. Thus, the present taste improving substances are advantageously applied in flavor compositions, foodstuffs, beverages, pharmaceutics, tobacco products and oral care products. Typical examples of flavor improving substances according to the present invention include N-lactoyl ethanolamine, N-lactoyl ethanolamine phosphate, N-α-hydroxy-butanoyl ethanolamine, N-lactoyl diethanolamine, N-lactoyl-2-amino-1,3-propanediol, N-lactoyl-3-amino-1,2-propanediol, N-lactoyl-3-amino-1-propanol, N-gluconyl-2-amino-1,3-propanediol, N-gluconyl-3-amino-1,2-propanediol, N-mannonyl ethanolamine, N-glycolyl ethanolamine, 2-hydroxyethyl-N-tartaramide, 2-hydroxyethyl-N-malamide, 2-hydroxyethyl-N-citramide and N-gluconyl-Az.
摘要翻译：本发明的第一方面涉及使用根据式（I）或式（II）的物质或其可食用盐的食品，饮料，药物，烟草制品和口腔护理产品的味道改善：R1-CR7（OR4 ）-CO-NR2-CR8R3-X-OR5（I）R6-CR7（OR4）-CO-Az（II）发现由式（I）和/或式（II）表示的物质能够调节和补充味道赋予物质的感官影响。因此，本发明的味道改善物质有利地用于风味组合物，食品，饮料，药物，烟草制品和口腔护理产品中。根据本发明的风味改良物质的典型实例包括N-乳酰乙醇胺，N-乳酰乙醇胺磷酸盐，N-α-羟基丁酰乙醇胺，N-乳酰二乙醇胺，N-乳酰-2-氨基-1,3-丙二醇，N-乳酰基-3-氨基-1,2-丙二醇，N-乳酰-3-氨基-1-丙醇，N-葡糖基-2-氨基-1,3-丙二醇，N-葡糖基-3-氨基-1 2-丙二醇，N-甘露糖醇乙醇胺，N-乙醇酰乙醇胺，2-羟乙基-N-苯甲酰胺，2-羟乙基-N-异丙酰胺，2-羟乙基-N-乙酰丙酰胺和N-葡萄糖基-Za。

3. 发明授权

US08293215B2 Flavour modulating derivative of a carboxylic acid and a purine, pyrimidine, nucleoside, or nucleotide 有权
标题翻译：调节羧酸和嘌呤，嘧啶，核苷或核苷酸的调味衍生物
公开(公告)号：US08293215B2
公开(公告)日：2012-10-23
申请号：US12517335
申请日：2007-12-13
申请人： Adri De Klerk , Marieke Baalbergen , Harry Renes , Chris Winkel
发明人： Adri De Klerk , Marieke Baalbergen , Harry Renes , Chris Winkel
IPC分类号： A61K8/18 , A61K8/00 , A23L1/22 , A23L2/56 , C07H19/167 , C07H19/04
CPC分类号： C07H19/04 , A23L27/202 , A23L27/23 , C07H19/16
摘要： The present invention relates to the field of improving the flavor of foodstuffs, beverages, tobacco products, pharmaceutics and oral care products. More particularly, the present invention provides flavor modulating substances selected from the group represented by formula (I): and edible salts thereof and edible esters thereof, which can advantageously be used for modulating the flavor of foodstuffs, beverages, tobacco products, pharmaceutics and oral care products. These flavor modulating substances can be used to impart desirable taste attributes in a wide variety of applications and products. In addition, the present flavor modulating substances are capable of modulating the taste and/or aroma impact of other, flavor imparting, substances contained within these same products, thereby improving the overall flavor quality of these products.
摘要翻译：本发明涉及改善食品，饮料，烟草制品，药物和口腔护理产品的风味的领域。更具体地，本发明提供了选自由式（I）表示的基团的风味调节物质及其食用盐和其食用酯，其可有利地用于调节食品，饮料，烟草制品，药物和口服的风味护理产品。这些风味调节物质可用于在各种应用和产品中赋予理想的味道特性。此外，本发明的风味调节物质能够调节这些相同产品中所含的其它赋香味物质的味道和/或香气的影响，从而提高这些产品的整体风味品质。

4. 发明申请

US20100056636A1 N-Substituted-P-Menthane-3-Carboxamide and Uses Thereof 审中-公开
标题翻译： N-取代的P-甲烷-3-羧酰胺及其用途
公开(公告)号：US20100056636A1
公开(公告)日：2010-03-04
申请号：US12519801
申请日：2007-11-30
申请人： Stefan Michael Furrer , Sander Tondeur , Chris Winkel , Harry Renes , Adri De klerk
发明人： Stefan Michael Furrer , Sander Tondeur , Chris Winkel , Harry Renes , Adri De klerk
IPC分类号： A61K31/166 , C07C233/57 , A61P25/00
CPC分类号： A23G4/06 , A23L27/20 , A23L27/204 , A24B15/301 , A61K8/42 , A61K2800/244 , A61Q5/02 , A61Q11/00 , A61Q15/00 , A61Q19/00 , C07C233/58 , C07C233/60 , C07C2601/02 , C07C2601/14
摘要： The present invention relates to substances and compositions having a physiological cooling effect on the skin and the mucosa of the body, especially of the oral cavity, throat and nose. More in particular, the present invention relates to N-substituted-p-menthane-3-carboxamides represented by the following formula (I): and esters thereof. These substances are capable of imparting and/or enhancing a physiological cooling effect in a product in which they are incorporated, much more effectively than the heretofore known N-substituted-p-menthane-3-carboxamides.
摘要翻译：本发明涉及具有对身体，特别是口腔，喉咙和鼻子的皮肤和粘膜的生理冷却作用的物质和组合物。更具体地，本发明涉及由下式（I）表示的N-取代对 - 薄荷烷-3-甲酰胺及其酯。这些物质能够赋予和/或增强其所掺入的产品中的生理冷却效果，比迄今为止已知的N-取代对薄荷烷-3-甲酰胺更有效。

5. 发明申请

US20080268122A1 Flavour Modulating Substances 有权
标题翻译：调味物质
公开(公告)号：US20080268122A1
公开(公告)日：2008-10-30
申请号：US12089043
申请日：2006-10-05
申请人： Harry Renes , Chris Winkel , Eric Kohlen , Jan Visser , Emelie Verhoek
发明人： Harry Renes , Chris Winkel , Eric Kohlen , Jan Visser , Emelie Verhoek
IPC分类号： A23L1/229 , A23L1/226 , A23L1/227
CPC分类号： C07C235/08 , A23L27/2028 , A23L27/21 , A23L27/23 , A23L33/145 , C12P13/04 , C12P13/12
摘要： The present invention in a first aspect relates to flavour modulation in foodstuffs, beverages, orally administered pharmaceuticals, tobacco products and oral care products, using a flavour modulating substance selected from the group of substances represented by formula, edible salts thereof and edible esters thereof: formula wherein R1 and/or R2 represent the residue of primary amines, more particularly the residues of primary amines selected from amino acids, peptides, purines and pyrimidines, aralkylamines and certain branched or straight chain, hydrophilically substituted alkylamines. It has been found that these substances are capable imparting highly desirable taste attributes in the products they are incorporated in. In addition said flavour modulating substances are advantageously applied in flavour compositions, foodstuffs, orally administered pharmaceuticals, tobacco products and oral care products.
摘要翻译：本发明的第一方面涉及使用选自由式表示的物质的组中的风味调节物质，食用盐和其食用酯的食品，饮料，口服药物，烟草制品和口腔护理产品中的调味剂，其中R 1和/或R 2代表伯胺的残基，更特别是选自氨基酸，肽，嘌呤和嘧啶的伯胺残基，芳烷基胺和某些支链或直链的亲水取代的烷基胺。已经发现，这些物质能够赋予其所掺入的产品中非常理想的味道特性。此外，所述风味调节物质有利地应用于风味组合物，食品，口服药物，烟草制品和口腔护理产品中。

6. 发明申请

US20080131573A1 Taste Improving Substances 有权
标题翻译：味道改善物质
公开(公告)号：US20080131573A1
公开(公告)日：2008-06-05
申请号：US11815233
申请日：2005-10-06
申请人： Chris Winkel , Harry Renes , Jan Visser , Nico Bouter , Jan Bakker , Bart Ruisch
发明人： Chris Winkel , Harry Renes , Jan Visser , Nico Bouter , Jan Bakker , Bart Ruisch
IPC分类号： A23L1/226 , A23L1/229
CPC分类号： A23L27/23
摘要： The present invention in a first aspect relates to taste improvement of foodstuffs, beverages, pharmaceutics, tobacco products and oral care products, using extremely small amounts of a substance according to formula (I), or edible salts thereof: R1—CR2(OR3)—CO—X (I). It was found that at very low concentrations, substances represented by formula (I) are capable of modifying and complementing, the sensory impact of taste imparting substances. Thus, the present taste improving substances are advantageously applied in flavour compositions, foodstuffs, pharmaceutics, tobacco products and oral care products. Typical examples of taste improving substances according to the present invention include N-lactoyl GMP, N-lactoyl AMP, N-lactoyl CMP, N-lactoyl IMP, N-gluconyl GMP, N-gluconyl AMP, N-gluconyl CMP, N-gluconyl IMP, O-lactoyl-GMP, O-lactoyl AMP, O-lactoyl CMP, O-lactoyl IMP, O-gluconyl GMP, O-gluconyl AMP, O-gluconyl CMP and O-gluconyl IMP and mixtures thereof.
摘要翻译：本发明的第一方面涉及使用极少量根据式（I）的物质或其可食用盐的食品，饮料，药物，烟草制品和口腔护理产品的味道改进：R 1，（OR 3）-OC-X（I）。发现在非常低的浓度下，由式（I）表示的物质能够改变和补充味道赋予物质的感官影响。因此，本发明的味道改善物质有利地用于风味组合物，食品，药物，烟草制品和口腔护理产品中。根据本发明的味道改善物质的典型实例包括N-乳酰基GMP，N-乳酰基AMP，N-乳酰基CMP，N-乳酰基IMP，N-葡萄糖基GMP，N-葡萄糖基AMP，N-葡萄糖基酰基CMP，N-葡萄糖基 IMP，O-乳酰基-GMP，O-乳酰基AMP，O-乳酰基CMP，O-乳酰基IMP，O-葡萄糖基GMP，O-葡萄糖基AMP，O-葡萄糖基酰基CMP和O-葡萄糖基IMP及其混合物。

7. 发明授权

US5084292A Processing for preparing flavorings and perfumes based on one or more carotenoids as starting material 失效
标题翻译：基于一种或多种作为起始材料的碳酸氢盐制备香料和香料的处理
公开(公告)号：US5084292A
公开(公告)日：1992-01-28
申请号：US528211
申请日：1990-05-25
申请人： Johannes M. Van Dort , Johannes T. De Heij , Harry Renes
发明人： Johannes M. Van Dort , Johannes T. De Heij , Harry Renes
IPC分类号： A23L27/20 , C07C403/16 , C07G99/00 , C11B9/00 , C11B9/02
CPC分类号： C11B9/0003 , A23L27/20
摘要： The invention provides a process for preparing flavouring and perfume complexes by converting one or more carotenoids like carotenes, xanthophylls etc. into a reaction product with organoleptic properties in the presence of a liquid solvent or liquid suspension medium containing an oxygen-containing gas at a temperature in the 20.degree.-250.degree. C. range under a pressure of not more than 400 bar. The obtained products--optionally after a complete or partial removal of the solvent or suspension medium--may be used for the direct or indirect perfuming and flavouring respectively of materials.
摘要翻译：本发明提供了一种通过在含有含氧气体的液体溶剂或液体悬浮介质的存在下，将一种或多种类胡萝卜素，胡萝卜素等转化成具有感官特性的反应产物来制备调味剂和香料复合物的方法，在20°-250℃范围内，压力不超过400巴。获得的产物 - 任选地在完全或部分除去溶剂或悬浮介质之后 - 可以分别用于直接或间接加香和调味料。

8. 发明授权

US07981457B2 Taste improving substances 有权
标题翻译：滋味改善物质
公开(公告)号：US07981457B2
公开(公告)日：2011-07-19
申请号：US11578443
申请日：2005-04-06
申请人： Jan Visser , Harry Renes , Chris Winkel , Nico Bouter
发明人： Jan Visser , Harry Renes , Chris Winkel , Nico Bouter
IPC分类号： A23L1/226 , A23L1/229
CPC分类号： A23L27/23 , A23L27/2054
摘要： The present invention in a first aspect relates to taste improvement of foodstuffs, beverages, pharmaceutics, tobacco products and oral care products, using a substance according to formula (I), or edible salts thereof: formula (I): R1—CR2(OR3)—CO—X. It was found that substances represented by formula (I) are capable of modifying and complementing, the sensory impact of taste imparting substances. Thus, the present taste improving substances are advantageously applied in flavour compositions, foodstuffs, pharmaceuticals, tobacco products and oral care products. Typical examples of taste improving substances according to the present invention include N-lactoyl GMP, N-lactoyl AMP, N-lactoyl CMP, N-lactoyl IMP, N-gluconyl GMP, N-gluconyl AMP, N-gluconyl CMP, N-gluconyl IMP, O-lactoyl-GMP, O-lactoyl AMP, O-lactoyl CMP, O-lactoyl IMP, O-gluconyl GMP, N-gluconyl AMP, O-gluconyl CMP and O-gluconyl IMP and the mixtures thereof.
摘要翻译：本发明的第一方面涉及使用根据式（I）的物质的食品，饮料，药物，烟草制品和口腔护理产品的味道改善或其食用盐：式（I）：R1-CR2（OR3 ）-CO-X。发现由式（I）表示的物质能够改变和补充味道赋予物质的感官影响。因此，本发明的味道改善物质有利地应用于风味组合物，食品，药物，烟草制品和口腔护理产品中。根据本发明的味道改善物质的典型实例包括N-乳酰基GMP，N-乳酰基AMP，N-乳酰基CMP，N-乳酰基IMP，N-葡萄糖基GMP，N-葡萄糖基AMP，N-葡萄糖基酰基CMP，N-葡萄糖基 IMP，O-乳酰基-GMP，O-乳酰基AMP，O-乳酰基CMP，O-乳酰基IMP，O-葡萄糖基GMP，N-葡萄糖基AMP，O-葡萄糖基酰基CMP和O-葡萄糖酸基IMP及其混合物。

9. 发明授权

US07897190B2 Flavour modulating substances 有权
标题翻译：调味物质
公开(公告)号：US07897190B2
公开(公告)日：2011-03-01
申请号：US11718288
申请日：2005-10-06
申请人： Chris Winkel , Harry Renes
发明人： Chris Winkel , Harry Renes
IPC分类号： A23L2/56
CPC分类号： C07C235/10 , A23L27/204
摘要： The present invention in a first aspect relates to novel flavour modulating substances according to formula (I) and/or edible salts thereof: R 1 —CR 2 (OR 3 ) —CO—NR 4 —Y—X (I). It was found that substances represented by formula (I) can advantageously be used to impart desirable flavour, especially taste attributes to foodstuffs, beverages, and pharmaceutics they are incorporated in. In addition said substances are capable of modulating and complementing the sensory impact of other, flavour imparting, substances. Thus, the present flavour modulating substances are advantageously applied in flavour compositions, foodstuffs, beverages and pharmaceutics. Typical examples of flavour modulating substances according to the present invention include N-lactoyl tyramine, Nqgluconyl tyramine, N-lactoyl 4-hydroxyben zylamine, N-lactoyl vanillylamine and N-lactoyl-dopamine.
摘要翻译：本发明的第一方面涉及根据式（I）和/或其食用盐的新颖风味调节物质：R 1 -CR 2（或） 3-CO-NR 4 -Y-X（I）。发现由式（I）表示的物质可以有利地用于赋予其所掺入的食品，饮料和药物所需的风味，特别是味道特性。此外，所述物质能够调节和补充其他物质的感官影响，赋香，物质。因此，本发明的风味调节物质有利地用于风味组合物，食品，饮料和药物中。根据本发明的风味调节物质的典型实例包括N-乳酰酪胺，NqGluconyl酪胺，N-乳酰基-4-羟基苯胺，N-乳酰基香草胺和N-乳酰基多巴胺。

10. 发明申请

US20100074850A1 Flavour Modulating Derivative of a Carboxylic Acid and a Purine, Pyrimidine, Nucleoside, or Nucleotide 有权
标题翻译：羧酸和嘌呤，嘧啶，核苷或核苷酸的调味衍生物
公开(公告)号：US20100074850A1
公开(公告)日：2010-03-25
申请号：US12517335
申请日：2007-12-13
申请人： Adri De Klerk , Marieke Baalbergen , Harry Renes , Chris Winkel
发明人： Adri De Klerk , Marieke Baalbergen , Harry Renes , Chris Winkel
IPC分类号： A61K8/60 , A23L1/226 , C07H19/16 , C07H19/20 , A61K31/708 , A61P43/00 , A61Q11/00 , A24B15/00
CPC分类号： C07H19/04 , A23L27/202 , A23L27/23 , C07H19/16
摘要： The present invention relates to the field of improving the flavour of foodstuffs, beverages, tobacco products, pharmaceutics and oral care products. More particularly, the present invention provides flavour modulating substances selected from the group represented by formula (1): and edible salts thereof and edible esters thereof, which can advantageously be used for modulating the flavour of foodstuffs, beverages, tobacco products, pharmaceutics and oral care products. These flavour modulating substances can be used to impart desirable taste attributes in a wide variety of applications and products. In addition, the present flavour modulating substances are capable of modulating the taste and/or aroma impact of other, flavour imparting, substances contained within these same products, thereby improving the overall flavour quality of these products.
摘要翻译：本发明涉及改善食品，饮料，烟草制品，药物和口腔护理产品的风味的领域。更具体地说，本发明提供了选自式（1）所示基团的风味调节物质及其食用盐及其食用酯，其可有利地用于调节食品，饮料，烟草产品，药物和口服的味道护理产品。这些风味调节物质可用于在各种应用和产品中赋予理想的味道特性。此外，本发明的风味调节物质能够调节这些相同产品中所含的其它赋香味物质的味道和/或香气的影响，从而提高这些产品的整体风味品质。

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