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1. 发明申请

US20120134666A1 OPTICAL FIBER-BASED DISTRIBUTED ANTENNA SYSTEMS, COMPONENTS, AND RELATED METHODS FOR MONITORING AND CONFIGURING THEREOF 有权
标题翻译：基于光纤的分布式天线系统，组件及其相关方法用于监视和配置
公开(公告)号：US20120134666A1
公开(公告)日：2012-05-31
申请号：US13194429
申请日：2011-07-29
申请人： Raymond A. Casterline , Gary L. Coakley , Vladimir M. Cotfas , Eric M. Sadowski , Michael Sauer , Dale A. Webb , Steven C. Kapp , Rajeshkannan Palanisamy , David R. Peters , Michael B. Webb
发明人： Raymond A. Casterline , Gary L. Coakley , Vladimir M. Cotfas , Eric M. Sadowski , Michael Sauer , Dale A. Webb , Steven C. Kapp , Rajeshkannan Palanisamy , David R. Peters , Michael B. Webb
IPC分类号： H04B10/08 , H04B10/12
CPC分类号： H04B10/25753 , H04B10/0795 , H04B10/25754 , H04B10/25756
摘要： Optical fiber-based wireless systems and related components and methods are disclosed. The systems support radio frequency (RF) communications with clients over optical fiber, including Radio-over-Fiber (RoF) communications. The systems may be provided as part of an indoor distributed antenna system (IDAS) to provide wireless communication services to clients inside a building or other facility. The communications can be distributed between a head end unit (HEU) that receives carrier signals from one or more service or carrier providers and converts the signals to RoF signals for distribution over optical fibers to end points, which may be remote antenna units (RAUs). A microprocessor-based control system or systems may also be employed. The control systems may include one or more microprocessors or microcontrollers in one or more of the components of the system that execute software instructions to control the various components and provide various features for the optical fiber-based distributed antenna systems.
摘要翻译：公开了基于光纤的无线系统及相关组件和方法。该系统通过光纤支持与客户端的射频（RF）通信，包括无线光纤（RoF）通信。该系统可以作为室内分布式天线系统（IDAS）的一部分提供，以向建筑物或其他设施内的客户提供无线通信服务。通信可以分配在从一个或多个服务或运营商提供商接收载波信号的头端单元（HEU）之间，并将信号转换成RoF信号，以通过光纤分配到端点，终端可以是远程天线单元（RAU）。还可以采用基于微处理器的控制系统或系统。控制系统可以包括系统的一个或多个组件中的一个或多个微处理器或微控制器，其执行软件指令以控制各种组件并为基于光纤的分布式天线系统提供各种特征。

2. 发明授权

US08049883B2 Wavelength tracker for swept wavelength sensor interrogation system 失效
标题翻译：扫描波长传感器询问系统的波长跟踪器
公开(公告)号：US08049883B2
公开(公告)日：2011-11-01
申请号：US12394109
申请日：2009-02-27
申请人： Michael B. Webb , Qi Wu
发明人： Michael B. Webb , Qi Wu
IPC分类号： G01J3/28
CPC分类号： G01J3/2803 , G01J3/02 , G01J3/0208 , G01J3/4338 , G01N21/7743
摘要： A swept wavelength interrogation system includes a tunable light source for outputting a light beam that is tunable over a range of wavelengths and an optical reader head for distributing the light beam among a plurality of sensors and for measuring response spectra from the sensors. A wavelength-tracking device measures centroid wavelengths of the light beam. A processor calculates a centroid wavelength of the response spectra from the sensors based on the measured centroid wavelengths of the light beam.
摘要翻译：扫频波长询问系统包括用于输出可在波长范围内调节的光束的可调谐光源和用于在多个传感器之间分配光束并用于测量来自传感器的响应光谱的光学读取头。波长跟踪装置测量光束的质心波长。处理器基于所测量的光束的质心波长来计算来自传感器的响应谱的质心波长。

3. 发明申请

US20110238382A1 OPTIMIZED METHOD FOR LID BIOSENSOR RESONANCE DETECTION 失效
标题翻译：用于生物传感器谐振检测的优化方法
公开(公告)号：US20110238382A1
公开(公告)日：2011-09-29
申请号：US13151605
申请日：2011-06-02
申请人： Jacques Gollier , Garrett A. Piech , Michael B. Webb , Qi Wu
发明人： Jacques Gollier , Garrett A. Piech , Michael B. Webb , Qi Wu
IPC分类号： G06F15/00 , G01J3/28
CPC分类号： G01J3/28 , G01J3/02 , G01J3/0218 , G01J3/1895 , G01J3/2803 , G01N21/7743
摘要： An optical interrogation system is described herein that can interrogate a label-independent-detection (LID) biosensor and monitor a biological event on top of the biosensor without suffering from problematical parasitic reflections and/or problematical pixelation effects.
摘要翻译：本文描述了一种光询问系统，其可以询问标签无关检测（LID）生物传感器并在生物传感器顶部监测生物事件，而不会遇到有问题的寄生反射和/或有问题的像素化效应。

4. 发明申请

US20110043828A1 OPTICAL READER SYSTEM AND METHOD FOR MONITORING AND CORRECTING LATERAL AND ANGULAR MISALIGNMENTS OF LABEL INDEPENDENT BIOSENSORS 审中-公开
标题翻译：用于监测和校正标签独立生物传感器的横向和角度误差的光学读取器系统和方法
公开(公告)号：US20110043828A1
公开(公告)日：2011-02-24
申请号：US12938740
申请日：2010-11-03
申请人： Anthony G. Frutos , Jacques Gollier , Jinlin Peng , Garrett A. Piech , Michael B. Webb
发明人： Anthony G. Frutos , Jacques Gollier , Jinlin Peng , Garrett A. Piech , Michael B. Webb
IPC分类号： G01N21/01 , G01B11/14
CPC分类号： G01N21/553 , G01N21/7743
摘要： An optical reader system and method are described herein that can detect a lateral and/or angular misalignment of one or more biosensors so that the biosensors can be properly re-located after being removed from and then reinserted into the optical reader system. In one embodiment, the biosensors are incorporated within the wells of a microplate.
摘要翻译：本文描述了可以检测一个或多个生物传感器的侧向和/或角度偏移的光学读取器系统和方法，使得生物传感器可以在从光学读取器系统中移除并重新插入到光学读取器系统之后被适当地重新定位。在一个实施方案中，将生物传感器并入微板的孔内。

5. 发明授权

US07851208B2 Optical reader system and method for monitoring and correcting lateral and angular misaligments of label independent biosensors 有权
标题翻译：用于监测和校正标签独立生物传感器的侧向和角度偏移的光学读取器系统和方法
公开(公告)号：US07851208B2
公开(公告)日：2010-12-14
申请号：US11789900
申请日：2007-04-26
申请人： Jacques Gollier , Garrett A. Piech , Michael B. Webb
发明人： Jacques Gollier , Garrett A. Piech , Michael B. Webb
IPC分类号： C12M3/0025
CPC分类号： G01N21/553 , G01N21/7743
摘要： An optical reader system and method are described herein that can detect a lateral and/or angular misalignment of one or more biosensors so that the biosensors can be properly re-located after being removed from and then reinserted into the optical reader system. In one embodiment, the biosensors are incorporated within the wells of a microplate.
摘要翻译：本文描述了可以检测一个或多个生物传感器的侧向和/或角度偏移的光学读取器系统和方法，使得生物传感器可以在从光学读取器系统中移除并重新插入到光学读取器系统之后被适当地重新定位。在一个实施方案中，将生物传感器并入微板的孔内。

6. 发明授权

US5598639A Tool for high temperature roll nip measurements 失效
标题翻译：用于高温辊隙测量的工具
公开(公告)号：US5598639A
公开(公告)日：1997-02-04
申请号：US477686
申请日：1995-06-07
申请人： Michael B. Webb
发明人： Michael B. Webb
IPC分类号： G01B7/14 , G01B21/06 , G01L5/00 , G03G15/20
CPC分类号： G01B7/14 , G01L5/0085 , G03G15/2064
摘要： Disclosed is a roll nip tool for making nip width measurements within a high temperature roll nip. The tool includes a first thin section for inserting into the high temperature roll nip. The first thin section includes a first surface that has a first portion of an electrical circuit formed thereon. The first thin section also includes a second thin member that has a second surface and a second portion of the electrical circuit formed thereon. The first thin member and the second thin member are attached together to form a pocket, and are arranged together such that the first and the second portions of the electrical circuit can be brought together into circuit closing contact within the pocket. The first thin section of the tool further includes a mechanism or suitable means such as pressurized air within the pocket for normally keeping the electrical circuit open by controllably separating the first and the second portions of the electrical circuit. The tool then includes a second section connected to the first thin section for indicating the achievement of closing contact between the first and the second portions of the electrical circuit.
摘要翻译：公开了一种用于在高温辊压区内进行压区宽度测量的辊压工具。该工具包括用于插入高温辊压区的第一薄部分。第一薄部分包括具有形成在其上的电路的第一部分的第一表面。第一薄部分还包括具有形成在其上的电路的第二表面和第二部分的第二薄部件。第一薄构件和第二薄构件附接在一起以形成凹穴，并且被布置在一起，使得电路的第一和第二部分可以一起进入袋内的电路闭合接触。该工具的第一薄部分还包括机构或适当的装置，例如袋内的加压空气，用于通过可控地分离电路的第一和第二部分来正常地保持电路断开。然后，该工具包括连接到第一薄部分的第二部分，用于指示实现电路的第一和第二部分之间的闭合接触。

7. 发明授权

US5571819A Imidazopyridines as muscarinic agents 失效
标题翻译：咪唑并吡啶类作为毒蕈碱药
公开(公告)号：US5571819A
公开(公告)日：1996-11-05
申请号：US343399
申请日：1994-11-22
申请人： Annmarie L. Sabb , Michael B. Webb
发明人： Annmarie L. Sabb , Michael B. Webb
IPC分类号： C07D471/04 , C07D519/00 , A61K31/435
CPC分类号： C07D471/04
摘要： The compound of the formula: ##STR1## where R.sub.1 is H, alkyl, perhaloalkyl, arylalkyl, alkenyl or alkynyl; R.sub.2 is H when R.sub.4 is other than H, and, when R.sub.4 is H, R.sub.2 is ##STR2## in which R.sub.5 is hydrogen or alkyl; R.sub.3 is hydrogen or halogen; R.sub.4 is H or ##STR3## X, Y and Z are, independently, nitrogen or carbon, at least one of X, Y or Z being nitrogen; n is 1 or 2; n.sub.1 is 0, 1, 2, 3, 4, or 5; or a pharmaceutically acceptable salt thereof are centrally active muscarinic agents.
摘要翻译：下式的化合物：其中R 1是H，烷基，全卤代烷基，芳基烷基，烯基或炔基; 当R4不为H时，R2为H，当R4为H时，R2为R5，其中R5为氢或烷基; R3是氢或卤素; R4是H或X，Y和Z独立地是氮或碳，X，Y或Z中的至少一个是氮; n为1或2; n1为0,1,2,3,4或5; 或其药学上可接受的盐是中枢活性毒蕈碱剂。

8. 发明申请

US20090138205A1 OPTIMIZED METHOD FOR LID BIOSENSOR RESONANCE DETECTION 有权
标题翻译：用于生物传感器谐振检测的优化方法
公开(公告)号：US20090138205A1
公开(公告)日：2009-05-28
申请号：US12266060
申请日：2008-11-06
申请人： Jacques Gollier , Garrett A. Piech , Michael B. Webb , Qi Wu
发明人： Jacques Gollier , Garrett A. Piech , Michael B. Webb , Qi Wu
IPC分类号： G06F19/00 , G06F15/00
CPC分类号： G01J3/28 , G01J3/02 , G01J3/0218 , G01J3/1895 , G01J3/2803 , G01N21/7743
摘要： An optical interrogation system is described herein that can interrogate a label-independent-detection (LID) biosensor and monitor a biological event on top of the biosensor without suffering from problematical parasitic reflections and/or problematical pixelation effects. In one embodiment, the optical interrogation system is capable of interrogating a biosensor and using a low pass filter algorithm to digitally remove problematic parasitic reflections contained in the spectrum of an optical resonance which makes it easier to determine whether or not a biological event occurred on the biosensor. In another embodiment, the optical interrogation system is capable of interrogating a biosensor and using an oversampling/smoothing algorithm to reduce oscillations in the estimated location of an optical resonance caused by the problematical pixelation effect which makes it easier to determine whether or not a biological event occurred on the biosensor.
摘要翻译：本文描述了一种光询问系统，其可以询问标签无关检测（LID）生物传感器并在生物传感器顶部监测生物事件，而不会遇到有问题的寄生反射和/或有问题的像素化效应。在一个实施例中，光询问系统能够询问生物传感器并使用低通滤波器算法来数字地去除包含在光学共振的光谱中的有问题的寄生反射，这使得更容易确定生物事件是否发生在生物传感器在另一个实施例中，光询问系统能够询问生物传感器并使用过采样/平滑算法来减少由问题像素化效应引起的光学共振的估计位置中的振荡，这使得更容易确定生物事件发生在生物传感器上。

9. 发明授权

US07509239B2 Optimized method for LID biosensor resonance detection 失效
标题翻译： LID生物传感器共振检测的优化方法
公开(公告)号：US07509239B2
公开(公告)日：2009-03-24
申请号：US11716425
申请日：2007-03-09
申请人： Jacques Gollier , Garrett A. Piech , Michael B. Webb , Qi Wu
发明人： Jacques Gollier , Garrett A. Piech , Michael B. Webb , Qi Wu
IPC分类号： G03F1/26
CPC分类号： G01J3/28 , G01J3/02 , G01J3/0218 , G01J3/1895 , G01J3/2803 , G01N21/7743
摘要： An optical interrogation system is described herein that can interrogate a label-independent-detection (LID) biosensor and monitor a biological event on top of the biosensor without suffering from problematical parasitic reflections and/or problematical pixelation effects. In one embodiment, the optical interrogation system is capable of interrogating a biosensor and using a low pass filter algorithm to digitally remove problematic parasitic reflections contained in the spectrum of an optical resonance which makes it easier to determine whether or not a biological event occurred on the biosensor. In another embodiment, the optical interrogation system is capable of interrogating a biosensor and using an oversampling/smoothing algorithm to reduce oscillations in the estimated location of an optical resonance caused by the problematical pixelation effect which makes it easier to determine whether or not a biological event occurred on the biosensor.
摘要翻译：本文描述了一种光询问系统，其可以询问标签无关检测（LID）生物传感器并在生物传感器顶部监测生物事件，而不会遇到有问题的寄生反射和/或有问题的像素化效应。在一个实施例中，光询问系统能够询问生物传感器并使用低通滤波器算法来数字地去除包含在光学共振的光谱中的有问题的寄生反射，这使得更容易确定生物事件是否发生在生物传感器在另一个实施例中，光询问系统能够询问生物传感器并使用过采样/平滑算法来减少由问题像素化效应引起的光学共振的估计位置中的振荡，这使得更容易确定生物事件发生在生物传感器上。

10. 发明申请

US20100105148A1 MULTI-CHANNEL SWEPT WAVELENGTH OPTICAL INTERROGATION SYSTEM AND METHOD FOR USING SAME 失效
标题翻译：多信道切换波长光学系统及其使用方法
公开(公告)号：US20100105148A1
公开(公告)日：2010-04-29
申请号：US12256852
申请日：2008-10-23
申请人： Stephen J. Caracci , Michael J. Dailey, JR. , William J. Miller , Robert A. Modavis , Deepti J. Mudaliar , David A. Pastel , Michael B. Webb , Qi Wu
发明人： Stephen J. Caracci , Michael J. Dailey, JR. , William J. Miller , Robert A. Modavis , Deepti J. Mudaliar , David A. Pastel , Michael B. Webb , Qi Wu
IPC分类号： G01N21/00 , G01N21/45 , G01N21/41
CPC分类号： G01N21/253 , G01N21/39 , G01N21/45
摘要： A multi-channel swept wavelength optical interrogation system and a method are described herein that enable the interrogation of one or more biosensors which for example could be located within the wells of a microplate. In one embodiment, the optical interrogation system comprises: (a) a tunable laser that emits an optical beam which has a predetermined sequence of distinct wavelengths over a predetermined time period; (b) a distribution unit that splits the optical beam into a plurality of interrogation beams; (c) an array of optical interrogation units that receive and direct the interrogation beams towards an array of biosensors; (d) the array of optical interrogation units receive a plurality of reflected interrogation beams from the array of biosensors; (e) a data processing device that receives and processes information associated with the reflected interrogation beams to determine for example whether or not there was a biochemical interaction on anyone of the biosensors.
摘要翻译：本文描述了多通道扫频波长光询问系统和方法，其能够询问一个或多个生物传感器，例如其可位于微板的孔内。在一个实施例中，光学询问系统包括：（a）可调激光器，其在预定时间段内发射具有预定的不同波长序列的光束; （b）分配单元，其将光束分成多个询问光束; （c）光学询问单元的阵列，其接收并将询问光束定向到生物传感器的阵列; （d）光学询问单元的阵列从生物传感器阵列接收多个反射询问光束; （e）数据处理装置，其接收和处理与所反映的询问光束相关联的信息，以确定例如生物传感器中任何一个生化交互是否存在。

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