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    • 1. 发明专利
    • Improvements relating to wall construction
    • GB346490A
    • 1931-04-16
    • GB284430
    • 1930-01-28
    • MATTHEW HUNTER THOMPSON
    • E04B2/86
    • 346,490. Walls. THOMPSON, M. H., Garnett Bridge, near Kendal, Westmorland. Jan. 28, 1930, No. 2844. [Class 20 (iv).] Concrete walls are cast in situ between a permanent outer shell of slates 15 and a temporary shuttering 13. The slates are suspended on wires 9 stretched between metal uprights 10, and are backed with cement or plaster 16 to form the outer shell. The metal uprights consist of two pairs of angle-irons 10 spaced by wooden blocks 11 and bolts, and each pair encloses wooden laths 12. At a corner of a wall, a triangular concrete post is cast in situ by erecting wooden strips 5, 6, 7, and rods 8, and enclosing these in temporary shuttering secured to the strips 5, 6, 7. After removal of the shuttering, lead flashing is secured to the corner strip 7, the wires 9 are fastened to the laths 12, and the wall is completed as described above. Internal fittings may be secured to the inner laths 12. Where more than one storey occurs, the ground floor walls are made double, as shown in Fig. 9.
    • 3. 发明申请
    • THERAPEUTIC AND SCREENING METHODS EMPLOYING PARTIAL AGONISM OF THE ∝-2A ADRENERGIC RECEPTOR SUBTYPE
    • 使用α-2A ADRENERGIC受体亚型的部分激动剂的治疗和筛选方法
    • WO2004009090A1
    • 2004-01-29
    • PCT/US2003/022209
    • 2003-07-17
    • VANDERBILT UNIVERSITYLIMBIRD, Lee, EberhardtTAN, Christopher, MichaelWILSON, Matthew, Hunter
    • LIMBIRD, Lee, EberhardtTAN, Christopher, MichaelWILSON, Matthew, Hunter
    • A61K31/506
    • A61K31/506
    • Methods employing partial agonism of the alpha-2A adrenergic receptor ((α 2A -AR) subtype in the treatment of attention deficit disorder (ADD), cognition enhancement, suppression of epilepsy, and protection against depression. The methods include the steps of administering a therapeutically effective amount of a weak partial agonist of the alpha 2A-adrenergic receptor subtype to the subject, wherein the weak partial agonist is selective for the alpha 2A-adrenergic receptor subtype; and treating the condition in the subject through the administering, wherein the treating occurs without evoking sedation in the subject. A method for identifying a selective, weak partial agonist for the alpha 2A-adrenergic receptor subtype is also disclosed. The method includes the steps of contacting the alpha 2A-adrenergic receptor subtype with a candidate compound; measuring a binding specificity, an activity level, or combination thereof of the alpha 2A adrenergic receptor subtype after the contacting; and determining that the candidate compound is a selective, weak partial agonist for the alpha 2A-adrenergic receptor subtype based on the measured binding specificity, activity level, or combination thereof.
    • 使用α-2A肾上腺素能受体((α2A-AR))亚型的部分激动治疗注意力缺陷障碍(ADD),认知增强,抑制癫痫和抑制抑制的方法,所述方法包括以下步骤: 有效量的α2A-肾上腺素能受体亚型的弱部分激动剂对受试者,其中所述弱部分激动剂对α2A-肾上腺素能受体亚型是选择性的;以及通过施用治疗受试者的状况,其中所述治疗发生 还公开了用于鉴定α2A-肾上腺素能受体亚型的选择性弱部分激动剂的方法,所述方法包括以下步骤:使α2A-肾上腺素能受体亚型与候选化合物接触;测量 接头后α2A肾上腺素能受体亚型的结合特异性,活性水平或其组合 G; 并且基于测量的结合特异性,活性水平或其组合,确定候选化合物是α2A-肾上腺素能受体亚型的选择性弱部分激动剂。
    • 5. 发明授权
    • Process and apparatus for molding a filter
    • 用于成型过滤器的方法和装置
    • US08936456B2
    • 2015-01-20
    • US13384472
    • 2010-07-23
    • David Matthew Hunter
    • David Matthew Hunter
    • B29C41/16B01D46/00B01D46/24B29C33/30B29C41/00B29L31/14
    • B01D46/0001B01D46/003B01D46/2403B29C33/302B29C41/003B29C41/16B29L2031/14
    • The invention provides a method for forming a fibrous layer within a tubular support, which comprises the steps of: (a) providing the tubular support; (b) providing forming mesh over the curved surface of the support and closing its ends against escape of fluid; and (c) introducing fibrous slurry (e.g. an aqueous slurry of borosilicate glass microfibers and water dispersible heat curable acrylic resin at a pH of about 3) from a pressurized source into an annular molding space between a rotary molding torpedo and an inner surface of the support, the torpedo having at least one channel for slurry opening along a curved surface thereof, fibers in the slurry collecting within the forming mesh to form the layer. The invention also provides apparatus for forming a fibrous layer within a tubular support, which comprises: (a) a mold having a molding space for the tubular support; (b) forming mesh in the molding space for covering an exterior curved surface of the support, the forming mesh being configured to collect fibers and permit liquid to pass through it; (c) headstock and tailstock end closures for closing headstock and tailstock ends of the support against escape of fluid; (d) a rotary molding torpedo extendible into and retractable from the molding space for defining with an internal curved surface of the support an annular space for formation of the fibrous layer, the torpedo having at least one channel for slurry opening along a curved surface thereof; (e) a drive coupled to the torpedo for rotation thereof during molding; and (f) a supply line for supplying fibrous slurry from a pressurized source to the torpedo for flow into and through the molding space; and (g) suction means for withdrawing fluid from the molding space.
    • 本发明提供一种在管状支撑件内形成纤维层的方法,其包括以下步骤:(a)提供管状支撑件; (b)在支撑件的弯曲表面上提供成形网,并关闭其端部以防止流体逸出; 和(c)将来自加压源的纤维浆料(例如硼硅酸盐玻璃微纤维和水分散性可热固化丙烯酸树脂的水性浆料)从加压源引入到旋转成型鱼雷和旋转成型鱼雷的内表面之间的环形模制空间 支撑件,鱼雷具有至少一个通道,用于沿着曲面的浆料开口,浆料中的纤维收集在成形网内以形成该层。 本发明还提供了一种用于在管状支撑件内形成纤维层的装置,其包括:(a)具有用于管状支撑件的模制空间的模具; (b)在所述模制空间中形成用于覆盖所述支撑件的外部曲面的网,所述成形网被构造成收集纤维并允许液体通过; (c)主轴箱和尾座端盖,用于封闭支架的主轴箱和尾座端,防止流体逸出; (d)旋转模制鱼雷可延伸到模制空间中并从模制空间缩回,用于限定支撑件的内部弯曲表面,用于形成纤维层的环形空间,鱼雷具有至少一个通道,用于沿其弯曲表面开放浆料 ; (e)在模制期间联接到鱼雷以使其旋转的驱动器; 和(f)用于将纤维浆料从加压源供应到鱼雷的供应管线,用于流入并通过模制空间; 和(g)用于从模制空间抽出流体的抽吸装置。
    • 8. 发明申请
    • Method and system for preventing illiteracy in struggling members of a predetermined set of students
    • 预防学生挣扎成员的文盲方法和制度
    • US20050100875A1
    • 2005-05-12
    • US10936386
    • 2004-09-08
    • Emery BestJeri NowakowskiMatthew HunterStephan Black
    • Emery BestJeri NowakowskiMatthew HunterStephan Black
    • G09B7/02G09B11/00G09B17/00G09B19/04
    • G09B7/02G09B11/00G09B17/00G09B19/04
    • A method and system for identifying a set of students who have encountered reading difficulty and are performing below grade level and intervening to prevent illiteracy and achieving grade-level literacy of struggling students. Standardized oral fluency assessments are administered for a predetermined set of at least one student in a database in a computer system. Results from the standardized oral fluency assessments are recorded for each student of the predetermined set in a database in a computer system. A standardized predictive measure of literacy is calculated on the computer system for each student, wherein the standardized predictive measure of literacy is a composite of the results stored in the database for each student. Struggling members of the predetermined set are identified based on each standardized predictive measure of literacy. An individual report for each struggling member is presented on a visual medium in communication with the computer system. Struggling members of the predetermined set are provided with specific individual recommendations of targeted intervention instruction and amount of instructional time whereby grade-level literacy is achieved.
    • 一种识别遇到阅读困难并在低于年级进行干预的学生的方法和系统,以防止文盲和实现挣扎学生的文化水平。 针对计算机系统中的数据库中的至少一个学生的预定组来管理标准化的口语流畅度评估。 记录在计算机系统中的数据库中的预定集合的每个学生的标准化口语流畅度评估的结果。 在每个学生的计算机系统上计算标准化的识字预测度量,其中标准化的识字预测度量是每个学生存储在数据库中的结果的组合。 基于每个标准化的识字预测度量来确定预定集合的挣扎成员。 每个挣扎成员的个人报告都呈现在与计算机系统通信的视觉媒体上。 具有针对性干预指导的具体个人建议以及实现年级识字率的教学时间的特定个人建议。
    • 9. 发明申请
    • PROCESS AND APPARATUS FOR MOLDING A FILTER
    • 用于成型过滤器的过程和装置
    • US20120267816A1
    • 2012-10-25
    • US13384472
    • 2010-07-23
    • David Matthew Hunter
    • David Matthew Hunter
    • B29C67/08
    • B01D46/0001B01D46/003B01D46/2403B29C33/302B29C41/003B29C41/16B29L2031/14
    • The invention provides a method for forming a fibrous layer within a tubular support, which comprises the steps of: (a) providing the tubular support; (b) providing forming mesh over the curved surface of the support and closing its ends against escape of fluid; and (c) introducing fibrous slurry (e.g. an aqueous slurry of borosilicate glass microfibers and water dispersible heat curable acrylic resin at a pH of about 3) from a pressurized source into an annular molding space between a rotary molding torpedo and an inner surface of the support, the torpedo having at least one channel for slurry opening along a curved surface thereof, fibers in the slurry collecting within the forming mesh to form the layer. The invention also provides apparatus for forming a fibrous layer within a tubular support, which comprises:(a) a mould having a molding space for the tubular support; (b) forming mesh in the molding space for covering an exterior curved surface of the support, the forming mesh being configured to collect fibers and permit liquid to pass through it; (c) headstock and tailstock end closures for closing headstock and tailstock ends of the support against escape of fluid; (d) a rotary molding torpedo extendible into and retractable from the molding space for defining with an internal curved surface of the support an annular space for formation of the fibrous layer, the torpedo having at least one channel for slurry opening along a curved surface thereof; (e) a drive coupled to the torpedo for rotation thereof during molding; and (f) a supply line for supplying fibrous slurry from a pressurized source to the torpedo for flow into and through the molding space; and (g) suction means for withdrawing fluid from the molding space.
    • 本发明提供一种在管状支撑件内形成纤维层的方法,其包括以下步骤:(a)提供管状支撑件; (b)在支撑件的弯曲表面上提供成形网,并关闭其端部以防止流体逸出; 和(c)将来自加压源的纤维浆料(例如硼硅酸盐玻璃微纤维和水分散性可热固化丙烯酸树脂的水性浆料)从加压源引入到旋转成型鱼雷和旋转成型鱼雷的内表面之间的环形模制空间 支撑件,鱼雷具有至少一个通道,用于沿着曲面的浆料开口,浆料中的纤维收集在成形网内以形成该层。 本发明还提供了一种用于在管状支撑件内形成纤维层的装置,其包括:(a)具有用于管状支撑件的模制空间的模具; (b)在所述模制空间中形成用于覆盖所述支撑件的外部曲面的网,所述成形网被构造成收集纤维并允许液体通过; (c)主轴箱和尾座端盖,用于封闭支架的主轴箱和尾座端,防止流体逸出; (d)旋转模制鱼雷可延伸到模制空间中并从模制空间缩回,用于限定支撑件的内部弯曲表面,用于形成纤维层的环形空间,鱼雷具有至少一个通道,用于沿其弯曲表面开放浆料 ; (e)在模制期间联接到鱼雷以使其旋转的驱动器; 和(f)用于将纤维浆料从加压源供应到鱼雷的供应管线,用于流入并通过模制空间; 和(g)用于从模制空间抽出流体的抽吸装置。