专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US4362736A Guanidinothiazole compounds, and medical compositions containing them 失效
标题翻译：胍基噻唑化合物和含有它们的医药组合物
公开(公告)号：US4362736A
公开(公告)日：1982-12-07
申请号：US127902
申请日：1980-03-06
申请人： Yasufumi Hirata , Isao Yanagisawa , Yoshio Ishii , Masaaki Takeda
发明人： Yasufumi Hirata , Isao Yanagisawa , Yoshio Ishii , Masaaki Takeda
IPC分类号： C07D277/38 , C07D277/46 , C07D277/48 , C07D277/20 , A61K31/425
CPC分类号： C07D277/48 , C07D277/46
摘要： Novel guanidinothiazole compounds of the general formula ##STR1## wherein R represents a hydrogen atom or a lower alkyl group, Y represents a sulfur atom or a methylene group, m and n each represents an integer of 1-3, A represents the group shown by ##STR2## (wherein R.sub.1 represents a hydrogen atom, a cyano group, a carbamoyl group, a ureido group, a hydroxyl group, a lower alkoxy group, a lower acyl group, an acylamino group, an arylsulfamoyl group, an aralkyl group or a carboxymethyl group, an arylsulfamoyl group, an aralkyl group or a carboxymethyl group, R.sub.2 represents a hydrogen atom, a lower alkyl group, a lower alkenyl group, a lower alkynyl group, a cyano group or a lower acyl group, and R.sub.3 represents a hydrogen atom, a lower alkyl group, a hydroxyl group or a sulfamoyl group), and the pharmacologically acceptable acid addition salts thereof; these compounds are useful as gastric acid secretion inhibitors.
摘要翻译：新颖的通式为“IMAGE”的胍基噻唑化合物，其中R表示氢原子或低级烷基，Y表示硫原子或亚甲基，m和n各自表示1-3的整数，A表示由（其中R 1表示氢原子，氰基，氨基甲酰基，脲基，羟基，低级烷氧基，低级酰基，酰氨基，芳基氨磺酰基，芳烷基或羧甲基，芳基氨磺酰基，芳烷基或羧甲基，R2表示氢原子，低级烷基，低级烯基，低级炔基，氰基或低级酰基，R3表示氢原子，低级烷基，羟基或氨磺酰基）及其药理学上可接受的酸加成盐; 这些化合物可用作胃酸分泌抑制剂。

2. 发明授权

US4321537A Fourier transform nuclear magnetic resonance spectrometer 失效
标题翻译：傅里叶变换核磁共振光谱仪
公开(公告)号：US4321537A
公开(公告)日：1982-03-23
申请号：US58430
申请日：1979-07-18
申请人： Hiroshi Yokokawa , Chutetsu Hattori , Masaaki Takeda
发明人： Hiroshi Yokokawa , Chutetsu Hattori , Masaaki Takeda
IPC分类号： G01R33/32 , G01R33/46 , G01N27/00
CPC分类号： G01R33/46
摘要： In a Fourier transform nuclear magnetic resonance spectrometer, as is known, a pulse modulated radio frequency is applied to a sample placed in a magnetic field, and a free induction decay signal resulting from the above application is Fourier transformed to obtain a nuclear magnetic resonance spectrum. In such a spectrometer, a material having a predetermined resonance peak, for example, tetramethylsilane is used as a reference sample, and the center frequency of the pulse modulated radio frequency is successively varied while maintaining a constant magnetic field intensity. The position of peak of tetramethylsilane in frequency spectra thus obtained is varied with the change of the center frequency. By measuring successively the signal strength of the peak, there can be obtained a frequency characteristic of a receiving system employed in the spectrometer, which is used to obtain correction coefficients of the receiving system. By multiplying a frequency spectrum of a sample to be analyzed by the correction coefficients, the frequency characteristic of the receiving system is corrected, and thus the signal strength of the frequency spectrum can be indicated with high accuracy.
摘要翻译：在已知的傅立叶变换核磁共振光谱仪中，将脉冲调制射频施加到放置在磁场中的样本，并且由上述应用得到的自由感应衰减信号被傅立叶变换以获得核磁共振谱。在这样的光谱仪中，使用具有规定的共振峰的材料，例如四甲基硅烷作为基准样品，脉冲调制射频的中心频率依次变化，同时保持恒定的磁场强度。这样获得的频谱中四甲基硅烷的峰位置随着中心频率的变化而变化。通过依次测量峰值的信号强度，可以获得用于获得接收系统的校正系数的光谱仪中使用的接收系统的频率特性。通过将要分析的样本的频谱乘以校正系数，校正接收系统的频率特性，从而可以高精度地指示频谱的信号强度。

3. 发明授权

US4097487A Pyrrolidinyl and piperidinyl benzamide derivatives 失效
标题翻译：吡咯烷基和哌啶基苯甲酰胺衍生物
公开(公告)号：US4097487A
公开(公告)日：1978-06-27
申请号：US671583
申请日：1976-03-29
申请人： Masuo Murakami , Kozo Takahashi , Yasufumi Hirata , Mutsuo Takashima , Sumio Iwanami , Osamu Hasegawa , Yoshihisa Nozaki , Shiro Tachikawa , Masaaki Takeda , Shinji Usuda
发明人： Masuo Murakami , Kozo Takahashi , Yasufumi Hirata , Mutsuo Takashima , Sumio Iwanami , Osamu Hasegawa , Yoshihisa Nozaki , Shiro Tachikawa , Masaaki Takeda , Shinji Usuda
IPC分类号： C07D207/09 , C07D209/14 , C07D211/26 , C07D213/53 , C07D217/14 , C07D307/52 , C07D207/16 , C07D211/60
CPC分类号： C07D213/53 , C07D207/09 , C07D209/14 , C07D211/26 , C07D217/14 , C07D307/52
摘要： The compounds of this invention are strong central nervous system depressants, in particular strong antipsychotics.
摘要翻译：其中R表示氢原子或低级烷基; X表示低级烷氧基; Y表示氢原子，氨基或单 - 或二 - 低级烷基氨基; Z表示卤素原子，低级烷氧基，低级烷硫基，低级烷基亚磺酰基，低级烷基磺酰基，氨磺酰基或低级烷基氨磺酰基; 所述Y和Z可以组合形成-N = N-NH-; W表示由下式表示的基团：其中A表示苯基，环己基，呋喃基或吡啶基; R 1，R 2和R 4可以相同或不同，不同的是，各自表示氢原子，低级烷基或苯基; R 3表示低级烷基，苯基低级烷基或二低级烷基氨基低级烷基; R 5，R 6和R 7可以相同或不同，各自表示氢原子，卤素原子，低级烷氧基，低级烷硫基，低级烷基亚磺酰基，低级烷基磺酰基或三氟甲基; R8表示低级烷基; n表示代表1或2），1-乙基-5-苯基-2-吡咯烷基甲基，1-乙基-2-异吲哚啉基甲基，2-乙基-1,2,3,4-四氢-4-异喹啉基， 2-（2-苯基吡咯烷子基）乙基，2-（2-异二氢吲哚基）乙基或2-（1,2,3,4-四氢-2-异喹啉基） - 乙基和药学上可接受的无毒盐其中。

4. 发明授权

US4041032A Pyrazine derivatives 失效
标题翻译：吡嗪衍生物
公开(公告)号：US4041032A
公开(公告)日：1977-08-09
申请号：US534636
申请日：1974-12-19
申请人： Masuo Murakami , Kozo Takahashi , Yasuhumi Hirata , Mutsuo Takashima , Masaaki Takeda , Hiroyoshi Ino , Sumio Iwanami
发明人： Masuo Murakami , Kozo Takahashi , Yasuhumi Hirata , Mutsuo Takashima , Masaaki Takeda , Hiroyoshi Ino , Sumio Iwanami
IPC分类号： C07D241/24 , C07D241/28
CPC分类号： C07D241/24 , Y10S514/872
摘要： Pyrazine derivatives by the formula ##STR1## are disclosed. In the above formula, R.sup.1 and R.sup.2, which may be the same or different, each represents a hydrogen atom, a halogen atom, a hydroxy group, a lower alkoxy group, a phenyl lower alkoxy group, a phenoxy group, a mercapto group, a lower alkylthio group, a phenyl lower alkylthio group, a phenylthio group, an amino group, a substituted amino group, a lower alkyl group, a carbamoyl group or a sulfamoyl group; R.sup.3 represents a lower alkoxy group; R.sup.4, R.sup.5, and R.sup.6, which may be the same or different, each represents a hydrogen atom, a lower alkyl group, a cycloalkyl group, a phenyl lower alkyl group, or a phenyl group; and A represents a lower alkylene group; said R.sup.4 and A, said R.sup.5 and A, said R.sup.4 and R.sup.5, or said R.sup.5 and R.sup.6 may form a 5-membered or 6-membered nitrogen-containing heterocyclic ring which may further contain a hetero-atom together with nitrogen atom, and the pharmacologically acceptable non-toxic salts thereof. The compounds of this invention have a strong and selective antiematic activity and an effect of stimulating the gastric motility.
摘要翻译：披露了通过式“IMAGE”的吡嗪衍生物。在上式中，R 1和R 2可以相同或不同，表示氢原子，卤素原子，羟基，低级烷氧基，苯基低级烷氧基，苯氧基，巯基，低级烷硫基，苯基低级烷硫基，苯硫基，氨基，取代氨基，低级烷基，氨基甲酰基或氨磺酰基; R3表示低级烷氧基; R 4，R 5和R 6可以相同或不同，分别表示氢原子，低级烷基，环烷基，苯基低级烷基或苯基。 A表示低级亚烷基; 所述R4和A表示R5和A表示R4和R5，或所述R5和R6可以形成还可以与氮原子一起含有杂原子的5元或6元含氮杂环，并且其药理学上可接受的无毒盐。本发明的化合物具有强的选择性的抗活性和刺激胃动力的作用。

5. 发明授权

US5488874A Liquid aspirating method 失效
标题翻译：液体抽吸法
公开(公告)号：US5488874A
公开(公告)日：1996-02-06
申请号：US211802
申请日：1994-07-05
申请人： Junichi Kawanabe , Masaaki Takeda , Hitomi Katagi , Yuko Kato , Gregory A. Bielarczyk , Rosie L. Magee
发明人： Junichi Kawanabe , Masaaki Takeda , Hitomi Katagi , Yuko Kato , Gregory A. Bielarczyk , Rosie L. Magee
IPC分类号： G01N1/00 , G01N35/10
CPC分类号： G01N35/109 , G01N2035/1025 , G01N2035/1034
摘要： The present invention aims to shorten an aspiration time, when aspirating a red blood cell component of a liquid sample having high viscosity. When aspirating the red blood cell component of a blood sample through a nozzle tip, a piston is pulled at its maximum to produce a maximum aspirating force, and starts aspiration. When a pressure in an aspirating system becomes equal to a predetermined value .alpha., the piston is returned to a position in which only a necessary aspiration volume of the liquid sample can be aspirated. Since the maximum aspirating force of the pump is utilized during the aspiration, the aspirating operation can be carried out more quickly.
摘要翻译： PCT No.PCT / JP92 / 01344 Sec。 371日期：1994年7月5日 102（e）日期1994年7月5日PCT提交1992年10月15日PCT公布。公开号WO93 / 08476 日期：1993年04月29日。本发明旨在缩短吸液时具有高粘度的液体样品的红细胞成分。当通过喷嘴尖吸出血液样本的红细胞成分时，将活塞拉至最大值以产生最大抽吸力，并开始抽吸。当抽吸系统中的压力变得等于预定值α时，活塞返回到只能抽吸液体样本的必要抽吸体积的位置。由于在抽吸期间利用泵的最大抽吸力，所以可以更快地进行抽吸操作。

6. 发明申请

US20090252943A1 ADIABATIC SOUND ABSORBER WITH HIGH THERMOSTABILITY 审中-公开
标题翻译：具有高热稳定性的ADIABATIC SOUND ABSORBER
公开(公告)号：US20090252943A1
公开(公告)日：2009-10-08
申请号：US12310056
申请日：2007-02-23
申请人： Masaaki Takeda , Hideo Nakamura
发明人： Masaaki Takeda , Hideo Nakamura
IPC分类号： B32B27/02
CPC分类号： D04H1/4382 , D04H1/4209
摘要： Provided is a flexible adiabatic sound absorber with high thermal insulation performance and acoustic performance, particularly an adiabatic sound absorbing material that is suitable for a new severe requirement specification regarding aircrafts. The adiabatic sound absorber comprises mixing uniformly 20 to 80% of a high-thermostable inorganic fiber whose high-temperature strength is maintained at 1000° C. or more, 10 to 60% of a flame-retarded organic fiber whose thermal melting or decomposition temperature is 350° C. or more and 10 to 25% of an organic fiber having a low melting point and treating the obtained woolly felt with heating to transform the whole into the mat-form material of 8 to 50 mm in thickness.
摘要翻译：提供了具有高绝热性能和声学性能的柔性绝热吸声器，特别是适用于关于飞机的新的严格要求规格的绝热吸声材料。绝热吸声器包括将高温强度保持在1000℃以上的高温高分子无机纤维20〜80％混合，加热熔融或分解温度为10〜60％的阻燃有机纤维为350℃以上10〜25％的低熔点有机纤维，加热处理得到的羊毛毡，将其整体转换成厚度为8〜50毫米的垫状材料。

7. 发明申请

US20050233161A1 Thermosetting adhesive sheet with electroconductive and thermoconductive properties 审中-公开
标题翻译：具有导电和导热性能的热固性粘合片
公开(公告)号：US20050233161A1
公开(公告)日：2005-10-20
申请号：US10508736
申请日：2003-04-01
申请人： Masaaki Takeda , Akihiko Mitsui , Kohichiro Kawate , Shigeyoshi Ishii
发明人： Masaaki Takeda , Akihiko Mitsui , Kohichiro Kawate , Shigeyoshi Ishii
IPC分类号： B32B27/00
CPC分类号： C09J9/02 , C08L2666/26 , C09J163/00 , Y10T428/31855
摘要： A thermosetting adhesive sheet with electroconductive and thermoconductive properties, which comprises a thermosetting adhesive sheet composed of a thermosetting adhesive composition comprising an ethylene-glycidyl(meth)acrylate copolymer and a carboxyl group-containing rosin, where crosslinking is formed between the ethylene of the copolymer by electron beam radiation, and having at least one through-opening region formed at a prescribed location, and further including a low melting point solder placed within said through-opening region(s) formed at the prescribed location(s).
摘要翻译：一种具有导电和导热特性的热固性粘合片，其包含由包含乙烯 - （甲基）丙烯酸缩水甘油酯共聚物和含羧基的松香的热固性粘合剂组合物组成的热固性粘合片，其中在共聚物的乙烯之间形成交联通过电子束辐射，并且具有形成在规定位置的至少一个通孔区域，并且还包括放置在形成在规定位置的所述通孔区域内的低熔点焊料。

8. 发明授权

US06590070B1 Thermosetting adhesive composition and adhered structure 失效
标题翻译：热固性粘合剂组合物和粘结结构
公开(公告)号：US06590070B1
公开(公告)日：2003-07-08
申请号：US09664686
申请日：2000-09-19
申请人： Naoyuki Toriumi , Koichiro Kawate , Masaaki Takeda , Shigeyoshi Ishii , Koji Itoh
发明人： Naoyuki Toriumi , Koichiro Kawate , Masaaki Takeda , Shigeyoshi Ishii , Koji Itoh
IPC分类号： C09F102
CPC分类号： C09J4/06 , C08F4/06 , C08F8/14 , C08F289/00 , C08L2666/02 , C08L2666/28 , C09J123/08 , Y10T428/31855 , Y10T428/31931 , C08F210/02 , C08F255/02
摘要： This invention provides thermosetting adhesives which have properties advantageous for bonding electronic parts that are capable of being cured using a low dose of radiation such as electron beam. The thermosetting adhesive of the invention comprises (a) ethylene-glycidyl (meth)acrylate copolymer; (b) rosin having a carboxyl group; and (c) (meth)acrylate having a carboxyl group.
摘要翻译：本发明提供热固性粘合剂，其具有有利于使用能够使用低剂量辐射如电子束固化的电子部件的性质。本发明的热固性粘合剂包含（a）乙烯 - （甲基）丙烯酸缩水甘油酯共聚物; （b）具有羧基的松香; 和（c）具有羧基的（甲基）丙烯酸酯。

9. 发明授权

US5537880A Automatic pipetting apparatus with leak detection and method of detecting a leak 失效
标题翻译：具有泄漏检测的自动移液装置和检测泄漏的方法
公开(公告)号：US5537880A
公开(公告)日：1996-07-23
申请号：US481677
申请日：1995-06-07
申请人： Masaaki Takeda , Yuko Kato , Brent A. Pelletier
发明人： Masaaki Takeda , Yuko Kato , Brent A. Pelletier
IPC分类号： G01M3/26 , G01N35/10
CPC分类号： G01N35/1016 , G01M3/26 , G01N2035/102
摘要： Embodiments described herein provide a pipetting apparatus with leak detection and a method for detecting a leak. In one embodiment, an automatic pipetting apparatus comprises a nozzle having a lower end portion through which a fluid sample is aspirated and dispensed by changes in air pressure supplied to the nozzle. A piping system operatively connects the nozzle to a pump for supplying the air pressure to the nozzle. A pressure sensor is operatively connected with the piping system for measuring internal pressure in the piping system. An XYZ robot is operatively connected with the nozzle for three-dimensionally moving the nozzle between an aspirating position of the fluid sample and a dispensing position. A leak detector is operatively connected with the pressure sensor for detecting a leak in the piping system based upon a measured result obtained by measuring the internal pressure in the piping system with the pressure sensor while the nozzle, which has aspirated a predetermined volume of the fluid sample, is being moved between the aspirating position and the dispensing position by the robot.
摘要翻译：本文所述的实施例提供了具有泄漏检测的移液装置和用于检测泄漏的方法。在一个实施例中，自动移液装置包括具有下端部分的喷嘴，通过该下端部抽吸流体样品并通过供给喷嘴的空气压力的变化来分配。管道系统将喷嘴可操作地连接到泵，以将空气压力提供给喷嘴。压力传感器与管道系统可操作地连接，用于测量管道系统中的内部压力。 XYZ机器人与喷嘴可操作地连接，用于在流体样品的抽吸位置和分配位置之间三维地移动喷嘴。泄漏检测器与压力传感器可操作地连接，用于基于通过用压力传感器测量管道系统中的内部压力而获得的测量结果来检测管道系统中的泄漏，同时吸入预定体积的流体样品由机器人在抽吸位置和分配位置之间移动。

10. 发明授权

US4379158A Antisecretory imidazole amidine compounds, composition and method of use 失效
标题翻译：咪唑咪唑类化合物，组成及使用方法
公开(公告)号：US4379158A
公开(公告)日：1983-04-05
申请号：US193742
申请日：1980-10-03
申请人： Yasufumi Hirata , Isao Yanagisawa , Toshinari Tamura , Masaaki Takeda
发明人： Yasufumi Hirata , Isao Yanagisawa , Toshinari Tamura , Masaaki Takeda
IPC分类号： C07D213/32 , C07D213/68 , C07D213/86 , C07D233/54 , C07D233/64 , C07D277/26 , C07D277/30 , C07D307/52 , A61K31/615 , C07D401/12
CPC分类号： C07D213/86 , C07D213/32 , C07D213/68 , C07D233/64 , C07D277/26 , C07D307/52
摘要： Novel heterocyclic compounds shown by the formula ##STR1## wherein Het represents a 5-membered or 6-membered heterocyclic group which may have substituent(s); Z represents a sulfur atom or oxygen atom; X represents an oxygen atom or the unsubstituted or substituted imino group shown by N--R.sub.1 (wherein R.sub.1 is a hydrogen atom, a lower alkyl group, a cyano group, an unsubstituted or alkyl substituted carbamoyl group, an unsubstituted or lower alkyl substituted thiocarbamoyl group, or a lower alkanoylamino group); Y represents a hydrogen atom, a lower alkyl group which may have substituent(s), a cycloalkyl group of 3-6 carbon atoms, a lower alkenyl group, a lower alkynyl group, an aryl group which may have substituent(s), an aralkyl group which may have substituent(s), a hydroxyl group, a cyano group, a carbamoyl group, an amidino group, an alkanoyl group which may have been substituted by halogen atom(s), an alkanoylamino group, an arylcarbonylamino group, an alkylamino group, an arylamino group, an arylsulfamoyl group, a lower alkoxycarbamoyl group, or an oxamoylamino group; and m and n represent an integer of 1-3; when X is N--R.sub.1, said X and Y may combine with each other to form a 5-membered or 6-membered heterocyclic ring containing 2-3 nitrogen atoms which may have substituent(s), and the pharmacologically acceptable acid addition salts thereof.The compounds of this invention are useful as gastric acid secretion inhibitors.
摘要翻译：式中，Het表示可具有取代基的5元或6元杂环基的新型杂环化合物。 Z表示硫原子或氧原子; X表示氧原子或由N-R 1表示的未取代或取代的亚氨基（其中R 1为氢原子，低级烷基，氰基，未取代或烷基取代的氨基甲酰基，未取代或低级烷基取代的硫代氨基甲酰基，或低级烷酰氨基）; Y表示氢原子，可具有取代基的低级烷基，3-6个碳原子的环烷基，低级烯基，低级炔基，可具有取代基的芳基，可以具有取代基的芳烷基，羟基，氰基，氨基甲酰基，脒基，可被卤素原子取代的烷酰基，烷酰基氨基，芳基羰基氨基，烷基氨基，芳基氨基，芳基氨磺酰基，低级烷氧基氨基甲酰基或氨甲酰基氨基; m和n表示1-3的整数; 当X是N-R1时，所述X和Y可以彼此结合形成含有2-3个可具有取代基的氮原子的5元或6元杂环，其药理学上可接受的酸加成盐。本发明的化合物可用作胃酸分泌抑制剂。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式