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1. 发明申请

WO2005009323A3 A NEBULISER FOR THE PRODUCTION OF AEROSOLIZED MEDICATION 审中-公开
标题翻译：用于生产气溶胶药物的基础
公开(公告)号：WO2005009323A3
公开(公告)日：2005-05-06
申请号：PCT/US2004021628
申请日：2004-07-06
申请人： AEROGEN INC , POWER JOHN , MORAN DECLAN , DEVERY DONAL , O'SULLIVAN GAVAN , FINK JAMES , SMITH NIALL
发明人： POWER JOHN , MORAN DECLAN , DEVERY DONAL , O'SULLIVAN GAVAN , FINK JAMES , SMITH NIALL
IPC分类号： A61M15/00 , A01G23/10 , A61M11/00 , A61M11/06 , B05B1/08 , B05B17/04
CPC分类号： A61M15/0085 , A61M2205/8206 , A61M2205/8237 , B05B17/0607
摘要： A nebuliser to deliver a medicament that includes a housing having a reservoir for the medicament, an aerosol generator that can be supplied the medicament from the reservoir, where the generator aerosolizes at least a portion of the medicament into an aerosol, a gas venting inlet to permit a gas to enter the nebuliser and form a mixture with the aerosol, and a passage through which the mixture of the aerosol and the gas is delivered to an outlet port of the nebuliser.
摘要翻译：一种用于递送药物的雾化器，其包括具有用于药物的储存器的壳体，可从储存器供应药物的气溶胶发生器，其中发生器将至少一部分药物雾化成气溶胶，气体通气入口允许气体进入雾化器并与气溶胶形成混合物，以及将气溶胶和气体的混合物输送到雾化器的出口的通道。

2. 发明申请

WO2011141475A1 AEROSOL GENERATOR ASSEMBLY 审中-公开
标题翻译：航空发电机总成
公开(公告)号：WO2011141475A1
公开(公告)日：2011-11-17
申请号：PCT/EP2011/057547
申请日：2011-05-10
申请人： NORTEV LIMITED , MORAN, Declan , O'SULLIVAN, Gavan
发明人： MORAN, Declan , O'SULLIVAN, Gavan
IPC分类号： A61M11/00 , B05B17/06
CPC分类号： B05B17/0676 , A61M11/005 , A61M15/0085 , A61M15/025 , A61M2202/0468 , B05B17/0646
摘要： An aerosol generator assembly comprising a vibratable piezo ceramic body (2) having first and second opposing sides, an aperture (o) defined in the vibratable body and extending through the body from the first side to the second side and having a layer of electrical contact material on each side of the vibratable body, the vibratable body being vibratable by application of an electrical signal thereto; a vibratable member (1) with pores defined therein, the vibratable member mounted across the aperture; and an electrical contact material free-zone (4) is provided on at least one side of the body about the aperture, characterised in that the electrical contact material free-zone and the vibratable member are dimensioned so that the vibratable member is mountable directly onto the vibratable body on top thereof within the electrical contact material free- zone such that a gap area free of electrode contact material is formed between the terminating edge of the electrical contact material and the periphery of the vibratable member.
摘要翻译：一种气溶胶发生器组件，包括具有第一和第二相对侧面的可振动压电陶瓷体（2），限定在所述可振动体中的孔（o），并且从所述第一侧延伸到所述第二侧并且具有一层电接触材料在可振动主体的每一侧上，可振动的主体可通过向其施加电信号而振动; 具有限定在其中的孔的可振动构件（1），所述可振动构件穿过所述孔安装; 并且在所述主体的至少一侧围绕所述孔提供电接触材料自由区（4），其特征在于，所述电接触材料自由区和所述可振动构件的尺寸被设计成使得所述可振动构件可直接安装到该电触点材料自由区内的可振动体在其顶部上，使得在电接触材料的终止边缘和可振动构件的周边之间形成没有电极接触材料的间隙区域。

3. 发明申请

WO2007024812A1 SELF-SEALING T-PIECE AND VALVED T-PIECE 审中-公开
标题翻译：自密封T型和阀门T型
公开(公告)号：WO2007024812A1
公开(公告)日：2007-03-01
申请号：PCT/US2006/032677
申请日：2006-08-21
申请人： AEROGEN, INC. , FINK, James, B. , O'SULLIVAN, Gavan , DUNNE, Paul , MORAN, Declan , POWER, John , SMITH, Niall
发明人： FINK, James, B. , O'SULLIVAN, Gavan , DUNNE, Paul , MORAN, Declan , POWER, John , SMITH, Niall
IPC分类号： A61M16/08
CPC分类号： A61M16/0833 , A61M11/00 , A61M15/009 , A61M16/0057 , A61M16/08 , A61M16/0875 , A61M16/14 , A61M16/20
摘要： Apparatus (500) and components for coupling fluid or gas conducting elements, such as apparatus and components for connecting a nebulizer (501) with a gas flow system. In particular, the apparatus (500) and components are useful for connecting, in a gas-tight and quick release manner, a nebulizer (501) to a pressure-assisted breathing system, such as a mechanical ventilator or a continuous positive airway pressure ("CPAP") system.
摘要翻译：用于耦合流体或气体传导元件的装置（500）和用于将雾化器（501）与气体流动系统连接的装置和部件。特别地，装置（500）和部件可用于以气密和快速释放的方式将雾化器（501）连接到诸如机械呼吸机或持续正压通气压力（例如， “CPAP”）系统。

4. 发明申请

WO2006102345A3 METHODS AND SYSTEMS FOR OPERATING AN AEROSOL GENERATOR 审中-公开
标题翻译：用于操作气溶胶发生器的方法和系统
公开(公告)号：WO2006102345A3
公开(公告)日：2007-01-25
申请号：PCT/US2006010278
申请日：2006-03-22
申请人： AEROGEN INC , FINK JAMES B , POWER JOHN , IVRI EHUD , SMITH NIALL , DUNNE PAUL , O'SULLIVAN GAVAN , MORAN DECLAN
发明人： FINK JAMES B , POWER JOHN , IVRI EHUD , SMITH NIALL , DUNNE PAUL , O'SULLIVAN GAVAN , MORAN DECLAN
IPC分类号： A61K9/12 , A61K9/72 , A61K31/7036 , A61K47/02 , A61M11/00 , A61M15/00 , A61M16/00 , A61M16/20
CPC分类号： A61M16/20 , A61K9/0078 , A61K31/7036 , A61M11/00 , A61M11/005 , A61M16/0833 , A61M16/0858 , A61M16/1065 , A61M16/208 , A61M2016/0021 , A61M2016/0027 , A61M2205/3561 , A61M2205/3569
摘要： A method of treating a patient with a pulmonary disease, where the method includes delivering a dose of aerosolized medicament intermittently to a ventilator circuit coupled to the respiratory system of the patient. Also, a method of treating a patient with a pulmonary disease, where the method includes taking the patient off a ventilator, and administering to the patient, a nebulized aerosol comprising from about 100 µg to about 500 mg of a medicament. Additionally, an aerosolized medicament for the treatment of a pulmonary disease, where the medicament includes amikacin mixed with an aqueous solution having an adjusted pH from about 5.5 to about 6.3. The pH is adjusted by adding hydrochloric acid and sodium hydroxide to the aqueous solution.
摘要翻译：一种治疗患有肺部疾病的患者的方法，其中所述方法包括将一定剂量的雾化药物间歇地递送至与患者呼吸系统相连的通气机回路。另外，一种治疗患有肺部疾病的患者的方法，其中所述方法包括使患者脱离呼吸机，并向患者施用包含约100μg至约500mg药物的雾化气雾剂。另外，一种用于治疗肺部疾病的雾化药物，其中药物包含与调节pH约5.5至约6.3的水溶液混合的阿米卡星。通过向水溶液中加入盐酸和氢氧化钠来调节pH。

5. 发明申请

WO2003041774A1 APPARATUS AND METHOD FOR DELIVERY OF MEDICAMENTS TO THE RESPIRATORY SYSTEM 审中-公开
标题翻译：用于向呼吸系统递送药物的装置和方法
公开(公告)号：WO2003041774A1
公开(公告)日：2003-05-22
申请号：PCT/IE2002/000154
申请日：2002-10-31
申请人： AEROGEN (IRELAND) LIMITED , POWER, John, Sylvester , REGAN, Desmond, John , MORAN, Declan
发明人： POWER, John, Sylvester , REGAN, Desmond, John , MORAN, Declan
IPC分类号： A61M11/00
CPC分类号： A61M16/14 , A61M15/0085 , A61M16/08 , A61M2205/8206 , A61M2205/8262 , A61M2209/082
摘要： An apparatus for delivery of a medicament to a respiratory system comprises a reservoir (2), an aerosol generator (3) for aerosolising liquid medicament and a connector (6) for entraining the aerosolised medicament from the aerosol generator (3) with a gas. The reservoir (2) has an upper inlet port (11) defined by a cap (10) and a lower outlet (16). The liquid medicament flows by gravitational action from the reservoir (2) to the aerosol generator (3). The cap (10) has a plug (12) which is opened for introduction of a volume of liquid medicament into the reservoir.
摘要翻译：用于将药物递送到呼吸系统的装置包括储存器（2），用于使液体药物气雾化的气溶胶发生器（3）和用气体从气溶胶发生器（3）夹带雾化的药物的连接器（6）。储存器（2）具有由盖（10）和下出口（16）限定的上入口（11）。液体药物通过重力作用从贮存器（2）流向气溶胶发生器（3）。盖（10）具有用于将一定体积的液体药物引入储存器的塞子（12）。

6. 发明申请

WO2011033092A1 INHALATION MASK FOR ANIMALS 审中-公开
标题翻译：动物吸入面膜
公开(公告)号：WO2011033092A1
公开(公告)日：2011-03-24
申请号：PCT/EP2010/063747
申请日：2010-09-17
申请人： NORTEV LIMITED , MORAN, Declan
发明人： MORAN, Declan
IPC分类号： A61D7/04
CPC分类号： A61D7/04
摘要： An inhalation mask (1) for fitting to a snout of an equine animal or an animal having an equine shaped snout is provided and comprise: a unitary mask body (6) defining a housing with an open end (11) which is adapted to overfit and accommodate the snout of the animal. The open end (11) of the housing being an integral part of the housing and forming a deformable seal about the open end (11) for sealing about the snout of the animal, wherein the open end (11) of the housing comprises a deformable lip (10) which forms the deformable seal, the lip (10) being formed by a continuation of a side wall (7) forming the mask body (6), which when the mask (1) is fitted, turns back inward upon itself, into the open end (11) of the mask (1), so that the lip (10) engages with the animal's snout to support the mask body (6) on the snout.
摘要翻译：提供一种用于装配到马动物或具有马形鼻孔的动物的鼻子的吸入口罩（1），其包括：整体式面罩主体（6），其限定具有开口端（11）的壳体，其适于过度并容纳动物的鼻子。壳体的开口端（11）是壳体的一体部分，并围绕开口端（11）形成可变形的密封，用于围绕动物的鼻孔密封，其中壳体的开口端（11）包括可变形的形成可变形密封件的唇缘（10），所述唇缘（10）由形成所述面罩主体（6）的侧壁（7）的延续形成，当所述面罩（1）被装配时，所述唇部（10）向内折回，进入面罩（1）的开口端（11），使得唇部（10）与动物的鼻子接合以将口罩主体（6）支撑在鼻孔上。

7. 发明申请

WO2005009323A2 A NEBULISER FOR THE PRODUCTION OF AEROSOLIZED MEDICATION 审中-公开
标题翻译：一种用于生产气溶胶药物的嗅觉器
公开(公告)号：WO2005009323A2
公开(公告)日：2005-02-03
申请号：PCT/US2004/021628
申请日：2004-07-06
申请人： AEROGEN, INC. , POWER, John , MORAN, Declan , DEVERY, Donal , O'SULLIVAN, Gavan , FINK, James , SMITH, Niall
发明人： POWER, John , MORAN, Declan , DEVERY, Donal , O'SULLIVAN, Gavan , FINK, James , SMITH, Niall
IPC分类号： A61J
CPC分类号： A61M15/0085 , A61M2205/8206 , A61M2205/8237 , B05B17/0607
摘要： A nebuliser to deliver a medicament that includes a housing having a reservoir for the medicament, an aerosol generator that can be supplied the medicament from the reservoir, where the generator aerosolizes at least a portion of the medicament into an aerosol, a gas venting inlet to permit a gas to enter the nebuliser and form a mixture with the aerosol, and a passage through which the mixture of the aerosol and the gas is delivered to an outlet port of the nebuliser.
摘要翻译：输送药物的雾化器，其包括具有用于药物的储存器的壳体，可从储存器供应药物的气雾剂发生器，其中发生器将药物的至少一部分雾化成气雾剂，允许气体进入雾化器并与气雾剂形成混合物的气体通气入口，以及气雾剂和气体的混合物通过该通道递送到雾化器的出口端口。

8. 发明申请

WO2006102345A2 METHODS AND SYSTEMS FOR OPERATING AN AEROSOL GENERATOR 审中-公开
标题翻译：用于操作气溶胶发生器的方法和系统
公开(公告)号：WO2006102345A2
公开(公告)日：2006-09-28
申请号：PCT/US2006/010278
申请日：2006-03-22
申请人： AEROGEN, INC. , FINK, James, B. , POWER, John , IVRI, Ehud , SMITH, Niall , DUNNE, Paul , O'SULLIVAN, Gavan , MORAN, Declan
发明人： FINK, James, B. , POWER, John , IVRI, Ehud , SMITH, Niall , DUNNE, Paul , O'SULLIVAN, Gavan , MORAN, Declan
IPC分类号： A61K9/12 , A61K9/72 , A61K47/02 , A61K31/7036 , A61M15/00 , A61M16/00
CPC分类号： A61M16/20 , A61K9/0078 , A61K31/7036 , A61M11/00 , A61M11/005 , A61M16/0833 , A61M16/0858 , A61M16/1065 , A61M16/208 , A61M2016/0021 , A61M2016/0027 , A61M2205/3561 , A61M2205/3569
摘要： A method of treating a patient with a pulmonary disease, where the method includes delivering a dose of aerosolized medicament intermittently to a ventilator circuit coupled to the respiratory system of the patient. Also, a method of treating a patient with a pulmonary disease, where the method includes taking the patient off a ventilator, and administering to the patient, a nebulized aerosol comprising from about 100 μg to about 500 mg of a medicament. Additionally, an aerosolized medicament for the treatment of a pulmonary disease, where the medicament includes amikacin mixed with an aqueous solution having an adjusted pH from about 5.5 to about 6.3. The pH is adjusted by adding hydrochloric acid and sodium hydroxide to the aqueous solution.
摘要翻译：一种治疗患有肺部疾病的患者的方法，其中所述方法包括将一定剂量的雾化药物间歇地递送至与患者呼吸系统相连的通气机回路。另外，一种治疗患有肺部疾病的患者的方法，其中所述方法包括使患者脱离呼吸机，并向患者施用包含约100μg至约500mg药物的雾化气雾剂。另外，一种用于治疗肺部疾病的雾化药物，其中药物包含与调节pH约5.5至约6.3的水溶液混合的阿米卡星。通过向水溶液中加入盐酸和氢氧化钠来调节pH。

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