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1. 发明申请

WO2011141475A1 AEROSOL GENERATOR ASSEMBLY 审中-公开
标题翻译：航空发电机总成
公开(公告)号：WO2011141475A1
公开(公告)日：2011-11-17
申请号：PCT/EP2011/057547
申请日：2011-05-10
申请人： NORTEV LIMITED , MORAN, Declan , O'SULLIVAN, Gavan
发明人： MORAN, Declan , O'SULLIVAN, Gavan
IPC分类号： A61M11/00 , B05B17/06
CPC分类号： B05B17/0676 , A61M11/005 , A61M15/0085 , A61M15/025 , A61M2202/0468 , B05B17/0646
摘要： An aerosol generator assembly comprising a vibratable piezo ceramic body (2) having first and second opposing sides, an aperture (o) defined in the vibratable body and extending through the body from the first side to the second side and having a layer of electrical contact material on each side of the vibratable body, the vibratable body being vibratable by application of an electrical signal thereto; a vibratable member (1) with pores defined therein, the vibratable member mounted across the aperture; and an electrical contact material free-zone (4) is provided on at least one side of the body about the aperture, characterised in that the electrical contact material free-zone and the vibratable member are dimensioned so that the vibratable member is mountable directly onto the vibratable body on top thereof within the electrical contact material free- zone such that a gap area free of electrode contact material is formed between the terminating edge of the electrical contact material and the periphery of the vibratable member.
摘要翻译：一种气溶胶发生器组件，包括具有第一和第二相对侧面的可振动压电陶瓷体（2），限定在所述可振动体中的孔（o），并且从所述第一侧延伸到所述第二侧并且具有一层电接触材料在可振动主体的每一侧上，可振动的主体可通过向其施加电信号而振动; 具有限定在其中的孔的可振动构件（1），所述可振动构件穿过所述孔安装; 并且在所述主体的至少一侧围绕所述孔提供电接触材料自由区（4），其特征在于，所述电接触材料自由区和所述可振动构件的尺寸被设计成使得所述可振动构件可直接安装到该电触点材料自由区内的可振动体在其顶部上，使得在电接触材料的终止边缘和可振动构件的周边之间形成没有电极接触材料的间隙区域。

2. 发明申请

WO2006102345A2 METHODS AND SYSTEMS FOR OPERATING AN AEROSOL GENERATOR 审中-公开
标题翻译：用于操作气溶胶发生器的方法和系统
公开(公告)号：WO2006102345A2
公开(公告)日：2006-09-28
申请号：PCT/US2006/010278
申请日：2006-03-22
申请人： AEROGEN, INC. , FINK, James, B. , POWER, John , IVRI, Ehud , SMITH, Niall , DUNNE, Paul , O'SULLIVAN, Gavan , MORAN, Declan
发明人： FINK, James, B. , POWER, John , IVRI, Ehud , SMITH, Niall , DUNNE, Paul , O'SULLIVAN, Gavan , MORAN, Declan
IPC分类号： A61K9/12 , A61K9/72 , A61K47/02 , A61K31/7036 , A61M15/00 , A61M16/00
CPC分类号： A61M16/20 , A61K9/0078 , A61K31/7036 , A61M11/00 , A61M11/005 , A61M16/0833 , A61M16/0858 , A61M16/1065 , A61M16/208 , A61M2016/0021 , A61M2016/0027 , A61M2205/3561 , A61M2205/3569
摘要： A method of treating a patient with a pulmonary disease, where the method includes delivering a dose of aerosolized medicament intermittently to a ventilator circuit coupled to the respiratory system of the patient. Also, a method of treating a patient with a pulmonary disease, where the method includes taking the patient off a ventilator, and administering to the patient, a nebulized aerosol comprising from about 100 μg to about 500 mg of a medicament. Additionally, an aerosolized medicament for the treatment of a pulmonary disease, where the medicament includes amikacin mixed with an aqueous solution having an adjusted pH from about 5.5 to about 6.3. The pH is adjusted by adding hydrochloric acid and sodium hydroxide to the aqueous solution.
摘要翻译：一种治疗患有肺部疾病的患者的方法，其中所述方法包括将一定剂量的雾化药物间歇地递送至与患者呼吸系统相连的通气机回路。另外，一种治疗患有肺部疾病的患者的方法，其中所述方法包括使患者脱离呼吸机，并向患者施用包含约100μg至约500mg药物的雾化气雾剂。另外，一种用于治疗肺部疾病的雾化药物，其中药物包含与调节pH约5.5至约6.3的水溶液混合的阿米卡星。通过向水溶液中加入盐酸和氢氧化钠来调节pH。

3. 发明申请

WO2005009323A2 A NEBULISER FOR THE PRODUCTION OF AEROSOLIZED MEDICATION 审中-公开
标题翻译：一种用于生产气溶胶药物的嗅觉器
公开(公告)号：WO2005009323A2
公开(公告)日：2005-02-03
申请号：PCT/US2004/021628
申请日：2004-07-06
申请人： AEROGEN, INC. , POWER, John , MORAN, Declan , DEVERY, Donal , O'SULLIVAN, Gavan , FINK, James , SMITH, Niall
发明人： POWER, John , MORAN, Declan , DEVERY, Donal , O'SULLIVAN, Gavan , FINK, James , SMITH, Niall
IPC分类号： A61J
CPC分类号： A61M15/0085 , A61M2205/8206 , A61M2205/8237 , B05B17/0607
摘要： A nebuliser to deliver a medicament that includes a housing having a reservoir for the medicament, an aerosol generator that can be supplied the medicament from the reservoir, where the generator aerosolizes at least a portion of the medicament into an aerosol, a gas venting inlet to permit a gas to enter the nebuliser and form a mixture with the aerosol, and a passage through which the mixture of the aerosol and the gas is delivered to an outlet port of the nebuliser.
摘要翻译：输送药物的雾化器，其包括具有用于药物的储存器的壳体，可从储存器供应药物的气雾剂发生器，其中发生器将药物的至少一部分雾化成气雾剂，允许气体进入雾化器并与气雾剂形成混合物的气体通气入口，以及气雾剂和气体的混合物通过该通道递送到雾化器的出口端口。

4. 发明申请

WO2007024812A1 SELF-SEALING T-PIECE AND VALVED T-PIECE 审中-公开
标题翻译：自密封T型和阀门T型
公开(公告)号：WO2007024812A1
公开(公告)日：2007-03-01
申请号：PCT/US2006/032677
申请日：2006-08-21
申请人： AEROGEN, INC. , FINK, James, B. , O'SULLIVAN, Gavan , DUNNE, Paul , MORAN, Declan , POWER, John , SMITH, Niall
发明人： FINK, James, B. , O'SULLIVAN, Gavan , DUNNE, Paul , MORAN, Declan , POWER, John , SMITH, Niall
IPC分类号： A61M16/08
CPC分类号： A61M16/0833 , A61M11/00 , A61M15/009 , A61M16/0057 , A61M16/08 , A61M16/0875 , A61M16/14 , A61M16/20
摘要： Apparatus (500) and components for coupling fluid or gas conducting elements, such as apparatus and components for connecting a nebulizer (501) with a gas flow system. In particular, the apparatus (500) and components are useful for connecting, in a gas-tight and quick release manner, a nebulizer (501) to a pressure-assisted breathing system, such as a mechanical ventilator or a continuous positive airway pressure ("CPAP") system.
摘要翻译：用于耦合流体或气体传导元件的装置（500）和用于将雾化器（501）与气体流动系统连接的装置和部件。特别地，装置（500）和部件可用于以气密和快速释放的方式将雾化器（501）连接到诸如机械呼吸机或持续正压通气压力（例如， “CPAP”）系统。

5. 发明授权

EP2569033B1 AEROSOL GENERATOR ASSEMBLY 有权
标题翻译：气雾剂发电机组件
公开(公告)号：EP2569033B1
公开(公告)日：2017-11-15
申请号：EP11718125.5
申请日：2011-05-10
申请人： Nortev Limited
发明人： MORAN, Declan , O'SULLIVAN, Gavan
IPC分类号： A61M11/00 , B05B17/06
CPC分类号： B05B17/0676 , A61M11/005 , A61M15/0085 , A61M15/025 , A61M2202/0468 , B05B17/0646

6. 发明公开

EP2569033A1 AEROSOL GENERATOR ASSEMBLY 有权
标题翻译： AEROSOLGENERATORANORDNUNG
公开(公告)号：EP2569033A1
公开(公告)日：2013-03-20
申请号：EP11718125.5
申请日：2011-05-10
申请人： Nortev Limited
发明人： MORAN, Declan , O'SULLIVAN, Gavan
IPC分类号： A61M11/00 , B05B17/06
CPC分类号： B05B17/0676 , A61M11/005 , A61M15/0085 , A61M15/025 , A61M2202/0468 , B05B17/0646
摘要： An aerosol generator assembly comprising a vibratable piezo ceramic body (2) having first and second opposing sides, an aperture (o) defined in the vibratable body and extending through the body from the first side to the second side and having a layer of electrical contact material on each side of the vibratable body, the vibratable body being vibratable by application of an electrical signal thereto; a vibratable member (1) with pores defined therein, the vibratable member mounted across the aperture; and an electrical contact material free-zone (4) is provided on at least one side of the body about the aperture, characterised in that the electrical contact material free-zone and the vibratable member are dimensioned so that the vibratable member is mountable directly onto the vibratable body on top thereof within the electrical contact material free- zone such that a gap area free of electrode contact material is formed between the terminating edge of the electrical contact material and the periphery of the vibratable member.
摘要翻译：一种气溶胶发生器组件，包括具有第一和第二相对侧的可振动压电陶瓷体（2），限定在可振动体中的孔（o），并且从第一侧延伸到第二侧并具有电接触层材料在可振动体的每一侧上，可振动体通过施加电信号而可振动; 具有限定在其中的孔的可振动构件（1），所述可振动构件横跨所述孔安装; 并且在所述本体的至少一侧围绕所述孔设置电接触材料自由区（4），其特征在于，所述电接触材料自由区和所述可振动构件的尺寸设定成使得所述可振动构件可直接安装在在电接触材料自由区的顶部上的可振动体，使得在电接触材料的终止边缘和可振动构件的周边之间形成没有电极接触材料的间隙区域。

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